Jean D. Beggs Wellcome Centre for Cell Biology, School of Biological Sciences University of Edinburgh Biography Publications Institution JoVE Articles Jean D. Beggs has not added a biography. If you are Jean D. Beggs and would like to personalize this page please email our Author Liaison for assistance. Publications Spt5 Modulates Co-transcriptional Spliceosome Assembly in RNA (New York, N.Y.). Jul, 2019 | Pubmed ID: 31289129 Mutagenesis of Snu114 Domain IV Identifies a Developmental Role in Meiotic Splicing RNA Biology. 02, 2019 | Pubmed ID: 30672374 A Fast and Tuneable Auxin-inducible Degron for Depletion of Target Proteins in Budding Yeast Yeast (Chichester, England). 01, 2019 | Pubmed ID: 30375036 A Nuclear Export Block Triggers the Decay of Newly Synthesized Polyadenylated RNA Cell Reports. Aug, 2018 | Pubmed ID: 30157437 Transcription Rate Strongly Affects Splicing Fidelity and Cotranscriptionality in Budding Yeast Genome Research. 02, 2018 | Pubmed ID: 29254943 RNA Polymerase II Stalling at Pre-mRNA Splice Sites is Enforced by Ubiquitination of the Catalytic Subunit ELife. 10, 2017 | Pubmed ID: 29027900 Extremely Fast and Incredibly Close: Cotranscriptional Splicing in Budding Yeast RNA (New York, N.Y.). 05, 2017 | Pubmed ID: 28153948 Transcriptome-wide RNA Processing Kinetics Revealed Using Extremely Short 4tU Labeling Genome Biology. Dec, 2015 | Pubmed ID: 26679539 Cwc21p Promotes the Second Step Conformation of the Spliceosome and Modulates 3' Splice Site Selection Nucleic Acids Research. Mar, 2015 | Pubmed ID: 25740649 Brr2p Carboxy-terminal Sec63 Domain Modulates Prp16 Splicing RNA Helicase Nucleic Acids Research. Dec, 2014 | Pubmed ID: 25428373 A Splicing-dependent Transcriptional Checkpoint Associated with Prespliceosome Formation Molecular Cell. Mar, 2014 | Pubmed ID: 24560925 A Rule-based Kinetic Model of RNA Polymerase II C-terminal Domain Phosphorylation Journal of the Royal Society, Interface. Sep, 2013 | Pubmed ID: 23804443 Structural Basis for Dual Roles of Aar2p in U5 SnRNP Assembly Genes & Development. Mar, 2013 | Pubmed ID: 23442228 RNA Helicases in Splicing RNA Biology. Jan, 2013 | Pubmed ID: 23229095 Brr2p-mediated Conformational Rearrangements in the Spliceosome During Activation and Substrate Repositioning Genes & Development. Nov, 2012 | Pubmed ID: 23124065 Kinetic Analysis of Pre-ribosome Structure in Vivo RNA (New York, N.Y.). Dec, 2012 | Pubmed ID: 23093724 Structure, Function and Regulation of Spliceosomal RNA Helicases Current Opinion in Cell Biology. Jun, 2012 | Pubmed ID: 22464735 Modelling Reveals Kinetic Advantages of Co-transcriptional Splicing PLoS Computational Biology. Oct, 2011 | Pubmed ID: 22022255 Mechanism for Aar2p Function As a U5 SnRNP Assembly Factor Genes & Development. Aug, 2011 | Pubmed ID: 21764848 Cross-linking, Ligation, and Sequencing of Hybrids Reveals RNA-RNA Interactions in Yeast Proceedings of the National Academy of Sciences of the United States of America. Jun, 2011 | Pubmed ID: 21610164 Splicing-dependent RNA Polymerase Pausing in Yeast Molecular Cell. Nov, 2010 | Pubmed ID: 21095588 RiboSys, a High-resolution, Quantitative Approach to Measure the in Vivo Kinetics of Pre-mRNA Splicing and 3'-end Processing in Saccharomyces Cerevisiae RNA (New York, N.Y.). Dec, 2010 | Pubmed ID: 20974745 Cross-talk in Transcription, Splicing and Chromatin: Who Makes the First Call? Biochemical Society Transactions. Oct, 2010 | Pubmed ID: 20863294 Brr2p RNA Helicase with a Split Personality: Insights into Structure and Function Biochemical Society Transactions. Aug, 2010 | Pubmed ID: 20659012 Processivity and Coupling in Messenger RNA Transcription PloS One. Jan, 2010 | Pubmed ID: 20126621 Physical and Genetic Interactions of Yeast Cwc21p, an Ortholog of Human SRm300/SRRM2, Suggest a Role at the Catalytic Center of the Spliceosome RNA (New York, N.Y.). Dec, 2009 | Pubmed ID: 19854871 Interaction of Yeast EIF4G with Spliceosome Components: Implications in Pre-mRNA Processing Events RNA Biology. Nov-Dec, 2009 | Pubmed ID: 19838078 Analysis of Lsm1p and Lsm8p Domains in the Cellular Localization of Lsm Complexes in Budding Yeast The FEBS Journal. Jul, 2009 | Pubmed ID: 19490016 Mutations in the U5 SnRNA Result in Altered Splicing of Subsets of Pre-mRNAs and Reduced Stability of Prp8 RNA (New York, N.Y.). Jul, 2009 | Pubmed ID: 19447917 A Role for Q/N-rich Aggregation-prone Regions in P-body Localization Journal of Cell Science. Aug, 2008 | Pubmed ID: 18611963 Requirements for Nuclear Localization of the Lsm2-8p Complex and Competition Between Nuclear and Cytoplasmic Lsm Complexes Journal of Cell Science. Dec, 2007 | Pubmed ID: 18029398 Prp8 Mutations That Cause Human Retinitis Pigmentosa Lead to a U5 SnRNP Maturation Defect in Yeast Nature Structural & Molecular Biology. Nov, 2007 | Pubmed ID: 17934474 The Lsm2-8 Complex Determines Nuclear Localization of the Spliceosomal U6 SnRNA Nucleic Acids Research. 2007 | Pubmed ID: 17251193 Yeast Ntr1/spp382 Mediates Prp43 Function in Postspliceosomes Molecular and Cellular Biology. Aug, 2006 | Pubmed ID: 16880513 Prp8p Dissection Reveals Domain Structure and Protein Interaction Sites RNA (New York, N.Y.). Feb, 2006 | Pubmed ID: 16373487 Crosstalk Between RNA Metabolic Pathways: an RNOMICS Approach Nature Reviews. Molecular Cell Biology. May, 2005 | Pubmed ID: 15956981 Prp8 Protein: at the Heart of the Spliceosome RNA (New York, N.Y.). May, 2005 | Pubmed ID: 15840809 Interaction Between a G-patch Protein and a Spliceosomal DEXD/H-box ATPase That is Critical for Splicing Molecular and Cellular Biology. Dec, 2004 | Pubmed ID: 15542821 Nuclear Pre-mRNA Decapping and 5' Degradation in Yeast Require the Lsm2-8p Complex Molecular and Cellular Biology. Nov, 2004 | Pubmed ID: 15485930 Lsm Proteins Promote Regeneration of Pre-mRNA Splicing Activity Current Biology : CB. Aug, 2004 | Pubmed ID: 15324666 Splicing Goes Global Trends in Genetics : TIG. Jun, 2003 | Pubmed ID: 12801718 Identification and Characterization of Prp45p and Prp46p, Essential Pre-mRNA Splicing Factors RNA (New York, N.Y.). Jan, 2003 | Pubmed ID: 12554883 Lsm Proteins Are Required for Normal Processing of Pre-tRNAs and Their Efficient Association with La-homologous Protein Lhp1p Molecular and Cellular Biology. Jul, 2002 | Pubmed ID: 12077351 Dhr1p, a Putative DEAH-box RNA Helicase, is Associated with the Box C+D SnoRNP U3 Molecular and Cellular Biology. Oct, 2000 | Pubmed ID: 10982841 Genome-wide Protein Interaction Screens Reveal Functional Networks Involving Sm-like Proteins Yeast (Chichester, England). Jun, 2000 | Pubmed ID: 10900456 Чрезвычайно быстрая и специфическая метаболическая маркировка РНК in Vivo с 4-Thiouracil (Ers4tU) J. David Barrass1, Jean D. Beggs1 1Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh JoVE 59952 Biochemistry Тюнинг деградации для достижения конкретных и эффективных истощения белка J. David Barrass1, Gonzalo I. Mendoza-Ochoa1,2, Isabella E. Maudlin1,3, Emanuela Sani1, Jean D. Beggs1 1Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, 2Department of Plant Sciences, University of Cambridge, 3Sir William Dunn School of Pathology, University of Oxford JoVE 59874 Immunology and Infection
Чрезвычайно быстрая и специфическая метаболическая маркировка РНК in Vivo с 4-Thiouracil (Ers4tU) J. David Barrass1, Jean D. Beggs1 1Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh JoVE 59952 Biochemistry
Тюнинг деградации для достижения конкретных и эффективных истощения белка J. David Barrass1, Gonzalo I. Mendoza-Ochoa1,2, Isabella E. Maudlin1,3, Emanuela Sani1, Jean D. Beggs1 1Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, 2Department of Plant Sciences, University of Cambridge, 3Sir William Dunn School of Pathology, University of Oxford JoVE 59874 Immunology and Infection
