Jean-Louis Mege Unité de Recherche sur les Maladies Infectieuses Tropicales et Emergentes (URMITE), CNRS UMR 7278, INSERM U1095 Aix Marseille Université Biography Publications Institution JoVE Articles Jean-Louis Mege has not added a biography. If you are Jean-Louis Mege and would like to personalize this page please email our Author Liaison for assistance. Publications Evaluation of Current and New Biomarkers in Severe Preeclampsia: A Microarray Approach Reveals TheVSIG4 Gene As a Potential Blood Biomarker PloS One. 2013 | Pubmed ID: 24349325 Placental Macrophages Are Impaired in Chorioamnionitis, an Infectious Pathology of the Placenta Journal of Immunology (Baltimore, Md. : 1950). Dec, 2013 | Pubmed ID: 24163411 Whole-cell MALDI-TOF Mass Spectrometry: a Tool for Immune Cell Analysis and Characterization Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23963939 Monocyte Responses in the Context of Q Fever: from a Static Polarized Model to a Kinetic Model of Activation The Journal of Infectious Diseases. Sep, 2013 | Pubmed ID: 23801603 Tobacco Mosaic Virus in the Lungs of Mice Following Intra-tracheal Inoculation PloS One. 2013 | Pubmed ID: 23383021 Pathogenic Brucellae Replicate in Human Trophoblasts The Journal of Infectious Diseases. Apr, 2013 | Pubmed ID: 23303808 Orientia Tsutsugamushi, the Causative Agent of Scrub Typhus, Induces an Inflammatory Program in Human Macrophages Microbial Pathogenesis. Feb, 2013 | Pubmed ID: 23088884 Chronic Hepatitis E Virus Infection is Specifically Associated with an Interferon-related Transcriptional Program The Journal of Infectious Diseases. Jan, 2013 | Pubmed ID: 23072754 Impaired Stimulation of P38α-MAPK/Vps41-HOPS by LPS from Pathogenic Coxiella Burnetii Prevents Trafficking to Microbicidal Phagolysosomes Cell Host & Microbe. Dec, 2012 | Pubmed ID: 23245320 Blood Leukocytes and Macrophages of Various Phenotypes Have Distinct Abilities to Form Podosomes and to Migrate in 3D Environments European Journal of Cell Biology. Nov-Dec, 2012 | Pubmed ID: 22999511 Overexpression of the Per2 Gene in Male Patients with Acute Q Fever The Journal of Infectious Diseases. Dec, 2012 | Pubmed ID: 22984121 Whole-cell MALDI-TOF MS: a New Tool to Assess the Multifaceted Activation of Macrophages Journal of Proteomics. Oct, 2012 | Pubmed ID: 22967923 Cross-protection Among Rickettsia Species and Subspecies in a Guinea Pig Model of Cutaneous Infection Comparative Immunology, Microbiology and Infectious Diseases. Dec, 2012 | Pubmed ID: 22784931 Immune Response and Coxiella Burnetii Invasion Advances in Experimental Medicine and Biology. 2012 | Pubmed ID: 22711638 Role of Innate and Adaptive Immunity in the Control of Q Fever Advances in Experimental Medicine and Biology. 2012 | Pubmed ID: 22711637 Defective Monocyte Dynamics in Q Fever Granuloma Deficiency The Journal of Infectious Diseases. Apr, 2012 | Pubmed ID: 22351939 The Gene Expression Analysis of Blood Reveals S100A11 and AQP9 As Potential Biomarkers of Infective Endocarditis PloS One. 2012 | Pubmed ID: 22319637 Foxp3(+)CD4(+)CD25(+) Regulatory T Cells Are Increased in Patients with Coxiella Burnetii Endocarditis FEMS Immunology and Medical Microbiology. Feb, 2012 | Pubmed ID: 22098165 Effects of Coxiella Burnetii on MAPKinases Phosphorylation FEMS Immunology and Medical Microbiology. Feb, 2012 | Pubmed ID: 22092597 The Ligands of Numb Proteins X1 and X2 Are Specific Markers for Chronic Q Fever FEMS Immunology and Medical Microbiology. Feb, 2012 | Pubmed ID: 22066909 An Evaluation of the Effects of Lactobacillus Ingluviei on Body Weight, the Intestinal Microbiome and Metabolism in Mice Microbial Pathogenesis. Jan, 2012 | Pubmed ID: 22020311 Effect of Rickettsial Toxin VapC on Its Eukaryotic Host PloS One. 2011 | Pubmed ID: 22046301 An Experimental Mouse Model to Establish Tropheryma Whipplei As a Diarrheal Agent The Journal of Infectious Diseases. Jul, 2011 | Pubmed ID: 21628657 Orientia Tsutsugamushi Stimulates an Original Gene Expression Program in Monocytes: Relationship with Gene Expression in Patients with Scrub Typhus PLoS Neglected Tropical Diseases. May, 2011 | Pubmed ID: 21610853 Circulating Matrix Metalloproteinases in Infective Endocarditis: a Possible Marker of the Embolic Risk PloS One. 2011 | Pubmed ID: 21533198 Macrophage Polarization and Bacterial Infections Current Opinion in Infectious Diseases. Jun, 2011 | Pubmed ID: 21311324 Hijacked Phagosomes and Leukocyte Activation: an Intimate Relationship Journal of Leukocyte Biology. Mar, 2011 | Pubmed ID: 20720162 Coxiella Burnetii, the Agent of Q Fever, Replicates Within Trophoblasts and Induces a Unique Transcriptional Response PloS One. 2010 | Pubmed ID: 21179488 Global Analysis of Circulating Immune Cells by Matrix-assisted Laser Desorption Ionization Time-of-flight Mass Spectrometry PloS One. 2010 | Pubmed ID: 21060873 IL-16 Promotes T. Whipplei Replication by Inhibiting Phagosome Conversion and Modulating Macrophage Activation PloS One. 2010 | Pubmed ID: 21042409 Sex-related Differences in Gene Expression Following Coxiella Burnetii Infection in Mice: Potential Role of Circadian Rhythm PloS One. 2010 | Pubmed ID: 20730052 3D Reconstruction of Granulomas from Transmitted Light Images Implemented for Long-time Microscope Applications Journal of Immunological Methods. Aug, 2010 | Pubmed ID: 20561526 Genomic, Proteomic, and Transcriptomic Analysis of Virulent and Avirulent Rickettsia Prowazekii Reveals Its Adaptive Mutation Capabilities Genome Research. May, 2010 | Pubmed ID: 20368341 [Is Macrophage Polarization the Gordian Knot of Bacterial Infections?] Médecine Sciences : M/S. Jan, 2010 | Pubmed ID: 20132780 The Transcriptional Programme of Human Heart Valves Reveals the Natural History of Infective Endocarditis PloS One. 2010 | Pubmed ID: 20126625 Type I Interferon Induction is Detrimental During Infection with the Whipple's Disease Bacterium, Tropheryma Whipplei PLoS Pathogens. Jan, 2010 | Pubmed ID: 20090833 Adipose Tissue Serves As a Reservoir for Recrudescent Rickettsia Prowazekii Infection in a Mouse Model PloS One. 2010 | Pubmed ID: 20049326 Three-dimensional Migration of Macrophages Requires Hck for Podosome Organization and Extracellular Matrix Proteolysis Blood. Feb, 2010 | Pubmed ID: 19897576 Intracellular Life of Coxiella Burnetii in Macrophages Annals of the New York Academy of Sciences. May, 2009 | Pubmed ID: 19538264 New Microbicidal Functions of Tracheal Glands: Defective Anti-infectious Response to Pseudomonas Aeruginosa in Cystic Fibrosis PloS One. 2009 | Pubmed ID: 19399182 Tropheryma Whipplei Glycosylation in the Pathophysiologic Profile of Whipple's Disease The Journal of Infectious Diseases. Apr, 2009 | Pubmed ID: 19222368 Macrophage Polarization in Bacterial Infections Journal of Immunology (Baltimore, Md. : 1950). Sep, 2008 | Pubmed ID: 18768823 Epidemic Typhus The Lancet Infectious Diseases. Jul, 2008 | Pubmed ID: 18582834 Ameobal Pathogen Mimivirus Infects Macrophages Through Phagocytosis PLoS Pathogens. Jun, 2008 | Pubmed ID: 18551172 The Uptake of Apoptotic Cells Drives Coxiella Burnetii Replication and Macrophage Polarization: a Model for Q Fever Endocarditis PLoS Pathogens. May, 2008 | Pubmed ID: 18483547 Rickettsial Diseases: from Rickettsia-arthropod Relationships to Pathophysiology and Animal Models Future Microbiology. Apr, 2008 | Pubmed ID: 18366341 Coxiella Burnetii, the Agent of Q Fever, Stimulates an Atypical M2 Activation Program in Human Macrophages European Journal of Immunology. Apr, 2008 | Pubmed ID: 18350541 Monocyte Deactivation in Neutropenic Acute Respiratory Distress Syndrome Patients Treated with Granulocyte Colony-stimulating Factor Critical Care (London, England). 2008 | Pubmed ID: 18282280 Nanobacteria Are Mineralo Fetuin Complexes PLoS Pathogens. Feb, 2008 | Pubmed ID: 18282102 Persistent Coxiella Burnetii Infection in Mice Overexpressing IL-10: an Efficient Model for Chronic Q Fever Pathogenesis PLoS Pathogens. Feb, 2008 | Pubmed ID: 18248094 Infection of Endothelial Cells with Virulent Rickettsia Prowazekii Increases the Transmigration of Leukocytes The Journal of Infectious Diseases. Jan, 2008 | Pubmed ID: 18171297 Preeclampsia: Impaired Inflammatory Response Mediated by Toll-like Receptors Journal of Reproductive Immunology. Jun, 2008 | Pubmed ID: 18023484 Coxiella Burnetii Infection in C57BL/6 Mice Aged 1 or 14 Months FEMS Immunology and Medical Microbiology. Aug, 2007 | Pubmed ID: 17555529 Increased Levels of Circulating IL-16 and Apoptosis Markers Are Related to the Activity of Whipple's Disease PloS One. 2007 | Pubmed ID: 17551575 A Murine Model of Infection with Rickettsia Prowazekii: Implications for Pathogenesis of Epidemic Typhus Microbes and Infection / Institut Pasteur. Jun, 2007 | Pubmed ID: 17537665 Vanin-1 Controls Granuloma Formation and Macrophage Polarization in Coxiella Burnetii Infection European Journal of Immunology. Jan, 2007 | Pubmed ID: 17163446 Coxiella Burnetii Stimulates Production of RANTES and MCP-1 by Mononuclear Cells: Modulation by Adhesion to Endothelial Cells and Its Implication in Q Fever European Cytokine Network. Dec, 2006 | Pubmed ID: 17353158 The Two Faces of Interleukin 10 in Human Infectious Diseases The Lancet Infectious Diseases. Sep, 2006 | Pubmed ID: 16931407 Murine Model of Infection by Tropheryma Whipplei Infection and Immunity. Aug, 2006 | Pubmed ID: 16861681 Deficient Transendothelial Migration of Leukocytes in Q Fever: the Role Played by Interleukin-10 The Journal of Infectious Diseases. Aug, 2006 | Pubmed ID: 16826485 CNF1-induced Ubiquitylation and Proteasome Destruction of Activated RhoA is Impaired in Smurf1-/- Cells Molecular Biology of the Cell. Jun, 2006 | Pubmed ID: 16540523 Role for the CD28 Molecule in the Control of Coxiella Burnetii Infection Infection and Immunity. Mar, 2006 | Pubmed ID: 16495554 Whipple's Disease: a Macrophage Disease Clinical and Vaccine Immunology : CVI. Feb, 2006 | Pubmed ID: 16467322 Antiangiogenic Effect of Erythromycin: an in Vitro Model of Bartonella Quintana Infection The Journal of Infectious Diseases. Feb, 2006 | Pubmed ID: 16388485 TLR2 is Necessary to Inflammatory Response in Coxiella Burnetii Infection Annals of the New York Academy of Sciences. Dec, 2005 | Pubmed ID: 16481508 Whipple Disease: Intestinal Infiltrating Cells Exhibit a Transcriptional Pattern of M2/alternatively Activated Macrophages The Journal of Infectious Diseases. Nov, 2005 | Pubmed ID: 16206080 IL-16 is Critical for Tropheryma Whipplei Replication in Whipple's Disease Journal of Immunology (Baltimore, Md. : 1950). Oct, 2005 | Pubmed ID: 16177102 Lack of Microbicidal Response in Human Macrophages Infected with Parachlamydia Acanthamoebae Microbes and Infection / Institut Pasteur. Apr, 2005 | Pubmed ID: 15826869 Intracellular Trafficking of Parachlamydia Acanthamoebae Cellular Microbiology. Apr, 2005 | Pubmed ID: 15760458 Ectoparasitism and Vector-borne Diseases in 930 Homeless People from Marseilles Medicine. Jan, 2005 | Pubmed ID: 15643300 Link Between Impaired Maturation of Phagosomes and Defective Coxiella Burnetii Killing in Patients with Chronic Q Fever The Journal of Infectious Diseases. Nov, 2004 | Pubmed ID: 15499532 Circulating Endothelial Microparticles in Malawian Children with Severe Falciparum Malaria Complicated with Coma JAMA : the Journal of the American Medical Association. Jun, 2004 | Pubmed ID: 15173142 Activation and Proteasomal Degradation of Rho GTPases by Cytotoxic Necrotizing Factor-1 Elicit a Controlled Inflammatory Response The Journal of Biological Chemistry. Aug, 2004 | Pubmed ID: 15152002 Lipopolysaccharide from Coxiella Burnetii is Involved in Bacterial Phagocytosis, Filamentous Actin Reorganization, and Inflammatory Responses Through Toll-like Receptor 4 Journal of Immunology (Baltimore, Md. : 1950). Mar, 2004 | Pubmed ID: 15004173 Effect of Sex on Coxiella Burnetii Infection: Protective Role of 17beta-estradiol The Journal of Infectious Diseases. Jan, 2004 | Pubmed ID: 14722900 Relationship of Relapsing Hip Prosthesis Infection by Staphylococcus Aureus with Gamma Interferon Deficiency Journal of Clinical Microbiology. Nov, 2003 | Pubmed ID: 14605201 Parachlamydia Acanthamoebae Enters and Multiplies Within Human Macrophages and Induces Their Apoptosis [corrected] Infection and Immunity. Oct, 2003 | Pubmed ID: 14500518 Deactivation of Alveolar Macrophages in Septic Neutropenic ARDS Chest. Aug, 2003 | Pubmed ID: 12907555 Interleukin-4 Induces Coxiella Burnetii Replication in Human Monocytes but Not in Macrophages Annals of the New York Academy of Sciences. Jun, 2003 | Pubmed ID: 12860673 Whipple's Disease: Immunospecific and Quantitative Immunohistochemical Study of Intestinal Biopsy Specimens Human Pathology. Jun, 2003 | Pubmed ID: 12827613 Coxiella Burnetii Avoids Macrophage Phagocytosis by Interfering with Spatial Distribution of Complement Receptor 3 Journal of Immunology (Baltimore, Md. : 1950). Apr, 2003 | Pubmed ID: 12682255 Dysregulation of Cytokines in Acute Q Fever: Role of Interleukin-10 and Tumor Necrosis Factor in Chronic Evolution of Q Fever The Journal of Infectious Diseases. Mar, 2003 | Pubmed ID: 12660942 Bartonella Quintana Bacteremia and Overproduction of Interleukin-10: Model of Bacterial Persistence in Homeless People The Journal of Infectious Diseases. Mar, 2003 | Pubmed ID: 12599058 IFN-gamma-induced Apoptosis and Microbicidal Activity in Monocytes Harboring the Intracellular Bacterium Coxiella Burnetii Require Membrane TNF and Homotypic Cell Adherence Journal of Immunology (Baltimore, Md. : 1950). Dec, 2002 | Pubmed ID: 12444137 Coxiella Burnetii Survival in THP-1 Monocytes Involves the Impairment of Phagosome Maturation: IFN-gamma Mediates Its Restoration and Bacterial Killing Journal of Immunology (Baltimore, Md. : 1950). Oct, 2002 | Pubmed ID: 12370385 Systemic Endothelial Activation is Greater in Septic Than in Traumatic-hemorrhagic Shock but Does Not Correlate with Endothelial Activation in Skin Biopsies Critical Care Medicine. Apr, 2002 | Pubmed ID: 11940750 Survival of Tropheryma Whipplei, the Agent of Whipple's Disease, Requires Phagosome Acidification Infection and Immunity. Mar, 2002 | Pubmed ID: 11854238 全细胞MALDI-TOF质谱法是一种准确,快速的方法来分析巨噬细胞活化的不同模式 Richard Ouedraogo1, Aurélie Daumas1,2, Christian Capo1, Jean-Louis Mege1, Julien Textoris1 1Unité de Recherche sur les Maladies Infectieuses Tropicales et Emergentes (URMITE), CNRS UMR 7278, INSERM U1095, Aix Marseille Université, 2Service de médecine interne, post-urgence et thérapeutique, Hôpital de la Timone Immunology and Infection
全细胞MALDI-TOF质谱法是一种准确,快速的方法来分析巨噬细胞活化的不同模式 Richard Ouedraogo1, Aurélie Daumas1,2, Christian Capo1, Jean-Louis Mege1, Julien Textoris1 1Unité de Recherche sur les Maladies Infectieuses Tropicales et Emergentes (URMITE), CNRS UMR 7278, INSERM U1095, Aix Marseille Université, 2Service de médecine interne, post-urgence et thérapeutique, Hôpital de la Timone Immunology and Infection