Jean-Marc Taymans Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences KU Leuven and Leuven Institute for Neuroscience and Disease (LIND) Biography Publications Institution JoVE Articles Jean-Marc Taymans has not added a biography. If you are Jean-Marc Taymans and would like to personalize this page please email our Author Liaison for assistance. Publications Identification of Protein Phosphatase 1 As a Regulator of the LRRK2 Phosphorylation Cycle The Biochemical Journal. Aug, 2013 | Pubmed ID: 23937259 MicroRNA-205 Regulates the Expression of Parkinson's Disease-related Leucine-rich Repeat Kinase 2 Protein Human Molecular Genetics. Feb, 2013 | Pubmed ID: 23125283 Phosphorylation of LRRK2: from Kinase to Substrate Biochemical Society Transactions. Oct, 2012 | Pubmed ID: 22988873 The GTPase Function of LRRK2 Biochemical Society Transactions. Oct, 2012 | Pubmed ID: 22988866 Biochemical Characterization of Highly Purified Leucine-rich Repeat Kinases 1 and 2 Demonstrates Formation of Homodimers PloS One. 2012 | Pubmed ID: 22952686 Expression, Purification and Preliminary Biochemical and Structural Characterization of the Leucine Rich Repeat Namesake Domain of Leucine Rich Repeat Kinase 2 Biochimica Et Biophysica Acta. Mar, 2012 | Pubmed ID: 22251894 LRRK2 Kinase Activity is Dependent on LRRK2 GTP Binding Capacity but Independent of LRRK2 GTP Binding PloS One. 2011 | Pubmed ID: 21858031 Kinases As Targets for Parkinson's Disease: from Genetics to Therapy CNS & Neurological Disorders Drug Targets. Sep, 2011 | Pubmed ID: 21838679 Insight into the Mode of Action of the LRRK2 Y1699C Pathogenic Mutant Journal of Neurochemistry. Jan, 2011 | Pubmed ID: 21073465 Automated Quantitative Gait Analysis in Animal Models of Movement Disorders BMC Neuroscience. 2010 | Pubmed ID: 20691122 免疫组织化学检测转基因表达中使用小的抗原表位标记的大脑。 BMC Biotechnology. 2010 | Pubmed ID: 20167102 抑制 FK506 结合蛋白减少了 α-synuclein 聚合和类似帕金森病的病理。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2010 | Pubmed ID: 20164329 Mechanisms in Dominant Parkinsonism: The Toxic Triangle of LRRK2, Alpha-synuclein, and Tau BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Mar, 2010 | Pubmed ID: 20127702 The Parkinson's Disease Associated LRRK2 Exhibits Weaker in Vitro Phosphorylation of 4E-BP Compared to Autophosphorylation PloS One. 2010 | Pubmed ID: 20090955 Phosphorylation of Ezrin/radixin/moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2009 | Pubmed ID: 19890007 The Parkinson's Disease Kinase LRRK2 Autophosphorylates Its GTPase Domain at Multiple Sites Biochemical and Biophysical Research Communications. Nov, 2009 | Pubmed ID: 19733152 帕金森病的相关亮氨酸-富重复激酶 2 (LRRK2) 是二聚体,分子内自磷酸化。 The Journal of Biological Chemistry. Jun, 2008 | Pubmed ID: 18397888 腺相关病毒载体在小鼠脑中的血清型 1、 2、 5、 7 和 8 的比较分析。 Human Gene Therapy. Mar, 2007 | Pubmed ID: 17343566 Distribution of PINK1 and LRRK2 in Rat and Mouse Brain Journal of Neurochemistry. Aug, 2006 | Pubmed ID: 16771836 Neuroscience Letters. Jan, 2006 | Pubmed ID: 16154268 富亮氨酸的代谢标记重复激酶1和2与放射性磷酸盐 Jean-Marc Taymans1, Fangye Gao1, Veerle Baekelandt1 1Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, KU Leuven and Leuven Institute for Neuroscience and Disease (LIND) JoVE 50523 Biology
富亮氨酸的代谢标记重复激酶1和2与放射性磷酸盐 Jean-Marc Taymans1, Fangye Gao1, Veerle Baekelandt1 1Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, KU Leuven and Leuven Institute for Neuroscience and Disease (LIND) JoVE 50523 Biology