Jean-Philippe Julien Program in Molecular Medicine The Hospital for Sick Children Research Institute Biography Publications Institution JoVE Articles Jean-Philippe Julien has not added a biography. If you are Jean-Philippe Julien and would like to personalize this page please email our Author Liaison for assistance. Publications Antihomotypic Affinity Maturation Improves Human B Cell Responses Against a Repetitive Epitope Science (New York, N.Y.). 06, 2018 | Pubmed ID: 29880723 Peek-Peak-Pique: Repeating Motifs of Subtle Variance Are Targets for Potent Malaria Antibodies Immunity. May, 2018 | Pubmed ID: 29768173 Molecular Basis of Unusually High Neutralization Resistance in Tier 3 HIV-1 Strain 253-11 Journal of Virology. 07, 2018 | Pubmed ID: 29618644 Structural Basis of Enhanced Crystallizability Induced by a Molecular Chaperone for Antibody Antigen-Binding Fragments Journal of Molecular Biology. Feb, 2018 | Pubmed ID: 29277294 Rare PfCSP C-terminal Antibodies Induced by Live Sporozoite Vaccination Are Ineffective Against Malaria Infection The Journal of Experimental Medicine. Jan, 2018 | Pubmed ID: 29167197 Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies Immunity. 12, 2017 | Pubmed ID: 29195810 Molecular Definition of Multiple Sites of Antibody Inhibition of Malaria Transmission-blocking Vaccine Antigen Pfs25 Nature Communications. Nov, 2017 | Pubmed ID: 29146922 Molecular Basis of Human CD22 Function and Therapeutic Targeting Nature Communications. 10, 2017 | Pubmed ID: 28970495 Key Residues at Third CDR3β Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs Journal of Immunology (Baltimore, Md. : 1950). 02, 2017 | Pubmed ID: 28003379 Discrete TCR Binding Kinetics Control Invariant NKT Cell Selection and Central Priming Journal of Immunology (Baltimore, Md. : 1950). Nov, 2016 | Pubmed ID: 27798168 Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design PLoS Pathogens. Aug, 2016 | Pubmed ID: 27560183 HIV-1 Broadly Neutralizing Antibody Precursor B Cells Revealed by Germline-targeting Immunogen Science (New York, N.Y.). Mar, 2016 | Pubmed ID: 27013733 EspP, an Extracellular Serine Protease from Enterohemorrhagic E. Coli, Reduces Coagulation Factor Activities, Reduces Clot Strength, and Promotes Clot Lysis PloS One. 2016 | Pubmed ID: 26934472 Design and Structure of Two HIV-1 Clade C SOSIP.664 Trimers That Increase the Arsenal of Native-like Env Immunogens Proceedings of the National Academy of Sciences of the United States of America. Sep, 2015 | Pubmed ID: 26372963 Origins of a Vaccine-Induced, Human Anti-HIV-1 Antibody EBioMedicine. Jul, 2015 | Pubmed ID: 26288832 Comprehensive Antigenic Map of a Cleaved Soluble HIV-1 Envelope Trimer PLoS Pathogens. Mar, 2015 | Pubmed ID: 25807248 Recombinant HIV Envelope Trimer Selects for Quaternary-dependent Antibodies Targeting the Trimer Apex Proceedings of the National Academy of Sciences of the United States of America. Dec, 2014 | Pubmed ID: 25422458 Karakterisering av glykoproteiner med immunglobulin luckan av röntgenkristallografi och biofysiska tekniker June Ereño-Orbea*1, Taylor Sicard*1,2, Hong Cui1, Indira Akula1, Jean-Philippe Julien1,2,3 1Program in Molecular Medicine, The Hospital for Sick Children Research Institute, 2Department of Biochemistry, University of Toronto, 3Department of Immunology, University of Toronto JoVE 57750 Biochemistry
Karakterisering av glykoproteiner med immunglobulin luckan av röntgenkristallografi och biofysiska tekniker June Ereño-Orbea*1, Taylor Sicard*1,2, Hong Cui1, Indira Akula1, Jean-Philippe Julien1,2,3 1Program in Molecular Medicine, The Hospital for Sick Children Research Institute, 2Department of Biochemistry, University of Toronto, 3Department of Immunology, University of Toronto JoVE 57750 Biochemistry