Jean-Philippe Julien Program in Molecular Medicine The Hospital for Sick Children Research Institute Biography Publications Institution JoVE Articles Jean-Philippe Julien has not added a biography. If you are Jean-Philippe Julien and would like to personalize this page please email our Author Liaison for assistance. Publications Antihomotypic Affinity Maturation Improves Human B Cell Responses Against a Repetitive Epitope Science (New York, N.Y.). 06, 2018 | Pubmed ID: 29880723 Peek-Peak-Pique: Repeating Motifs of Subtle Variance Are Targets for Potent Malaria Antibodies Immunity. May, 2018 | Pubmed ID: 29768173 Molecular Basis of Unusually High Neutralization Resistance in Tier 3 HIV-1 Strain 253-11 Journal of Virology. 07, 2018 | Pubmed ID: 29618644 Structural Basis of Enhanced Crystallizability Induced by a Molecular Chaperone for Antibody Antigen-Binding Fragments Journal of Molecular Biology. Feb, 2018 | Pubmed ID: 29277294 Rare PfCSP C-terminal Antibodies Induced by Live Sporozoite Vaccination Are Ineffective Against Malaria Infection The Journal of Experimental Medicine. Jan, 2018 | Pubmed ID: 29167197 Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies Immunity. 12, 2017 | Pubmed ID: 29195810 Molecular Definition of Multiple Sites of Antibody Inhibition of Malaria Transmission-blocking Vaccine Antigen Pfs25 Nature Communications. Nov, 2017 | Pubmed ID: 29146922 Molecular Basis of Human CD22 Function and Therapeutic Targeting Nature Communications. 10, 2017 | Pubmed ID: 28970495 Key Residues at Third CDR3β Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs Journal of Immunology (Baltimore, Md. : 1950). 02, 2017 | Pubmed ID: 28003379 Discrete TCR Binding Kinetics Control Invariant NKT Cell Selection and Central Priming Journal of Immunology (Baltimore, Md. : 1950). Nov, 2016 | Pubmed ID: 27798168 Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design PLoS Pathogens. Aug, 2016 | Pubmed ID: 27560183 HIV-1 Broadly Neutralizing Antibody Precursor B Cells Revealed by Germline-targeting Immunogen Science (New York, N.Y.). Mar, 2016 | Pubmed ID: 27013733 EspP, an Extracellular Serine Protease from Enterohemorrhagic E. Coli, Reduces Coagulation Factor Activities, Reduces Clot Strength, and Promotes Clot Lysis PloS One. 2016 | Pubmed ID: 26934472 Design and Structure of Two HIV-1 Clade C SOSIP.664 Trimers That Increase the Arsenal of Native-like Env Immunogens Proceedings of the National Academy of Sciences of the United States of America. Sep, 2015 | Pubmed ID: 26372963 Origins of a Vaccine-Induced, Human Anti-HIV-1 Antibody EBioMedicine. Jul, 2015 | Pubmed ID: 26288832 Comprehensive Antigenic Map of a Cleaved Soluble HIV-1 Envelope Trimer PLoS Pathogens. Mar, 2015 | Pubmed ID: 25807248 Recombinant HIV Envelope Trimer Selects for Quaternary-dependent Antibodies Targeting the Trimer Apex Proceedings of the National Academy of Sciences of the United States of America. Dec, 2014 | Pubmed ID: 25422458 X-ışını kristalografisi ve biyofiziksel teknikleri immünglobulin katlanmış glikoproteinlerin karakterizasyonu June Ereño-Orbea*1, Taylor Sicard*1,2, Hong Cui1, Indira Akula1, Jean-Philippe Julien1,2,3 1Program in Molecular Medicine, The Hospital for Sick Children Research Institute, 2Department of Biochemistry, University of Toronto, 3Department of Immunology, University of Toronto JoVE 57750 Biochemistry
X-ışını kristalografisi ve biyofiziksel teknikleri immünglobulin katlanmış glikoproteinlerin karakterizasyonu June Ereño-Orbea*1, Taylor Sicard*1,2, Hong Cui1, Indira Akula1, Jean-Philippe Julien1,2,3 1Program in Molecular Medicine, The Hospital for Sick Children Research Institute, 2Department of Biochemistry, University of Toronto, 3Department of Immunology, University of Toronto JoVE 57750 Biochemistry
