Jean-Yves Masson Oncology Division Genome Stability Laboratory, CHU de Québec Research Center, HDQ Pavilion Biography Publications Institution JoVE Articles Jean-Yves Masson has not added a biography. If you are Jean-Yves Masson and would like to personalize this page please email our Author Liaison for assistance. Publications Addressing the Dark Matter of Gene Therapy: Technical and Ethical Barriers to Clinical Application Human Genetics. Apr, 2021 | Pubmed ID: 33834266 Animal Models of Fanconi Anemia: A Developmental and Therapeutic Perspective on a Multifaceted Disease Seminars in Cell & Developmental Biology. May, 2021 | Pubmed ID: 33558144 Limiting the DNA Double-Strand Break Resectosome for Genome Protection Trends in Biochemical Sciences. 09, 2020 | Pubmed ID: 32513599 Poly(ADP-ribose) Polymerase-1 Antagonizes DNA Resection at Double-strand Breaks Nature Communications. 07, 2019 | Pubmed ID: 31273204 The Tumor Suppressor PALB2: Inside Out Trends in Biochemical Sciences. 03, 2019 | Pubmed ID: 30638972 Coupling of Homologous Recombination and the Checkpoint by ATR Molecular Cell. Jan, 2017 | Pubmed ID: 28089683 [Functions of PALB2 and BRCA2 Tumor Suppressors in DNA Double-strand Break Repair] Médecine Sciences : M/S. Mar, 2013 | Pubmed ID: 23544385 Fanconi Anemia Group J Helicase and MRE11 Nuclease Interact to Facilitate the DNA Damage Response Molecular and Cellular Biology. Jun, 2013 | Pubmed ID: 23530059 Detection of the HIV-1 Minus-strand-encoded Antisense Protein and Its Association with Autophagy Journal of Virology. May, 2013 | Pubmed ID: 23427159 Reprogramming Cellular Events by Poly(ADP-ribose)-binding Proteins Molecular Aspects of Medicine. Dec, 2013 | Pubmed ID: 23268355 The RAD51 Paralogs Ensure Cellular Protection Against Mitotic Defects and Aneuploidy Journal of Cell Science. Jan, 2013 | Pubmed ID: 23108668 PALB2 Self-interaction Controls Homologous Recombination Nucleic Acids Research. Nov, 2012 | Pubmed ID: 22941656 PARP Activation Regulates the RNA-binding Protein NONO in the DNA Damage Response to DNA Double-strand Breaks Nucleic Acids Research. Nov, 2012 | Pubmed ID: 22941645 Synthesis, Biological Evaluation, and Structure-activity Relationships of Novel Substituted N-phenyl Ureidobenzenesulfonate Derivatives Blocking Cell Cycle Progression in S-phase and Inducing DNA Double-strand Breaks Journal of Medicinal Chemistry. Jul, 2012 | Pubmed ID: 22694057 A Requirement for Polymerized Actin in DNA Double-strand Break Repair Nucleus (Austin, Tex.). Jul, 2012 | Pubmed ID: 22688650 Interactions Between BRCA2 and RAD51 for Promoting Homologous Recombination in Leishmania Infantum Nucleic Acids Research. Aug, 2012 | Pubmed ID: 22505581 CBX4-mediated SUMO Modification Regulates BMI1 Recruitment at Sites of DNA Damage Nucleic Acids Research. Jul, 2012 | Pubmed ID: 22402492 The MicroRNA Pathway Controls Germ Cell Proliferation and Differentiation in C. Elegans Cell Research. Jun, 2012 | Pubmed ID: 22370633 ChAM, a Novel Motif That Mediates PALB2 Intrinsic Chromatin Binding and Facilitates DNA Repair EMBO Reports. Feb, 2012 | Pubmed ID: 22193777 The MRE11 GAR Motif Regulates DNA Double-strand Break Processing and ATR Activation Cell Research. Feb, 2012 | Pubmed ID: 21826105 Irinotecan and DNA-PKcs Inhibitors Synergize in Killing of Colon Cancer Cells Investigational New Drugs. Jun, 2012 | Pubmed ID: 21221710 Partners Apart: Smc6-independent DNA Binding Activity of Smc5 on Single-strand DNA Cell Cycle (Georgetown, Tex.). Apr, 2011 | Pubmed ID: 21415594 The Effect of a DNA Repair Gene on Cellular Invasiveness: XRCC3 Over-expression in Breast Cancer Cells PloS One. 2011 | Pubmed ID: 21283680 Lactococcal Phage P2 ORF35-Sak3 is an ATPase Involved in DNA Recombination and AbiK Mechanism Molecular Microbiology. Apr, 2011 | Pubmed ID: 21276096 A Key Role for Poly(ADP-ribose) Polymerase 3 in Ectodermal Specification and Neural Crest Development PloS One. 2011 | Pubmed ID: 21264220 Proteome-wide Identification of WRN-interacting Proteins in Untreated and Nuclease-treated Samples Journal of Proteome Research. Mar, 2011 | Pubmed ID: 21210717 乳房がんタンパク質 PALB2 と刺激的な相同組換えでピッコロ BRCA2 の協力。 Nature Structural & Molecular Biology. Oct, 2010 | Pubmed ID: 20871615 Deciphering the Function of Lactococcal Phage Ul36 Sak Domains Journal of Structural Biology. Jun, 2010 | Pubmed ID: 20036743 FANCD2: A DNA Binding Protein Regulated by MRE11-RAD50-NBS1 Cell Cycle (Georgetown, Tex.). Jan, 2010 | Pubmed ID: 20023418 Structure and Function of Phage P2 ORF34(p2), a New Type of Single-stranded DNA Binding Protein Molecular Microbiology. Sep, 2009 | Pubmed ID: 19719513 MRE11-RAD50-NBS1 is a Critical Regulator of FANCD2 Stability and Function During DNA Double-strand Break Repair The EMBO Journal. Aug, 2009 | Pubmed ID: 19609304 The Werner Syndrome Protein Affects the Expression of Genes Involved in Adipogenesis and Inflammation in Addition to Cell Cycle and DNA Damage Responses Cell Cycle (Georgetown, Tex.). Jul, 2009 | Pubmed ID: 19502800 Recovery of Deficient Homologous Recombination in Brca2-depleted Mouse Cells by Wild-type Rad51 Expression DNA Repair. Feb, 2009 | Pubmed ID: 18992372 Functional and Structural Basis for a Bacteriophage Homolog of Human RAD52 Current Biology : CB. Aug, 2008 | Pubmed ID: 18656357 A Glycine-arginine Domain in Control of the Human MRE11 DNA Repair Protein Molecular and Cellular Biology. May, 2008 | Pubmed ID: 18285453 PARP1-dependent Kinetics of Recruitment of MRE11 and NBS1 Proteins to Multiple DNA Damage Sites The Journal of Biological Chemistry. Jan, 2008 | Pubmed ID: 18025084 Stimulation of Fission Yeast and Mouse Hop2-Mnd1 of the Dmc1 and Rad51 Recombinases Nucleic Acids Research. 2007 | Pubmed ID: 17426123 Twists and Turns in the Function of DNA Damage Signaling and Repair Proteins by Post-translational Modifications DNA Repair. May, 2007 | Pubmed ID: 17258515 Interplay Between Human DNA Repair Proteins at a Unique Double-strand Break in Vivo The EMBO Journal. Jan, 2006 | Pubmed ID: 16395335 The Transcriptional Histone Acetyltransferase Cofactor TRRAP Associates with the MRN Repair Complex and Plays a Role in DNA Double-strand Break Repair Molecular and Cellular Biology. Jan, 2006 | Pubmed ID: 16382133 Targeting Poly(ADP-ribosyl)ation: a Promising Approach in Cancer Therapy Trends in Molecular Medicine. Oct, 2005 | Pubmed ID: 16154385 [A New Role for Arginine Methylation in DNA Repair] Médecine Sciences : M/S. Jun-Jul, 2005 | Pubmed ID: 15985195 Methylation of MRE11 Regulates Its Nuclear Compartmentalization Cell Cycle (Georgetown, Tex.). Jul, 2005 | Pubmed ID: 15970667 Fission Yeast Rad51 and Dmc1, Two Efficient DNA Recombinases Forming Helical Nucleoprotein Filaments Molecular and Cellular Biology. Jun, 2005 | Pubmed ID: 15899844 The Hop2 and Mnd1 Proteins Act in Concert with Rad51 and Dmc1 in Meiotic Recombination Nature Structural & Molecular Biology. May, 2005 | Pubmed ID: 15834424 Arginine Methylation of MRE11 by PRMT1 is Required for DNA Damage Checkpoint Control Genes & Development. Mar, 2005 | Pubmed ID: 15741314 Exploring the Multiple Facets of the Meiotic Recombinase Dmc1 BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Nov, 2004 | Pubmed ID: 15499584 Direct Interaction of FANCD2 with BRCA2 in DNA Damage Response Pathways Human Molecular Genetics. Jun, 2004 | Pubmed ID: 15115758 Conformational Changes Modulate the Activity of Human RAD51 Protein Journal of Molecular Biology. Apr, 2004 | Pubmed ID: 15033353 Chromatin Remodeling and the Maintenance of Genome Integrity Biochimica Et Biophysica Acta. Mar, 2004 | Pubmed ID: 15020056 RAD51C is Required for Holliday Junction Processing in Mammalian Cells Science (New York, N.Y.). Jan, 2004 | Pubmed ID: 14716019 XRCC3 and Rad51 Modulate Replication Fork Progression on Damaged Vertebrate Chromosomes Molecular Cell. Apr, 2003 | Pubmed ID: 12718895 Role of Mammalian RAD51L2 (RAD51C) in Recombination and Genetic Stability The Journal of Biological Chemistry. May, 2002 | Pubmed ID: 11912211 BrdU-DNA標識と細胞周期判別イメージングを用いたグローバルDNA二本鎖末端切除の評価 Julia O'Sullivan*1,2, Sofiane Y. Mersaoui*1,2, Guy Poirier2,3, Jean-Yves Masson1,2 1Oncology Division, Genome Stability Laboratory, CHU de Québec Research Center, HDQ Pavilion, 2Department of Molecular Biology, Medical Biochemistry, and Pathology, Laval University Cancer Research Center, 3Oncology Division, CHU de Québec Research Center, CHUL Pavilion JoVE 62553 Biology GST-Hisの精製：全長精製タンパク質を降伏二段階アフィニティー精製プロトコル Ranjan Maity*1, Joris Pauty*1, Jana Krietsch*1, Rémi Buisson1, Marie-Michelle Genois1, Jean-Yves Masson1 1Genome Stability Laboratory, Oncology Axis, Hôtel-Dieu de Québec JoVE 50320 Biology
BrdU-DNA標識と細胞周期判別イメージングを用いたグローバルDNA二本鎖末端切除の評価 Julia O'Sullivan*1,2, Sofiane Y. Mersaoui*1,2, Guy Poirier2,3, Jean-Yves Masson1,2 1Oncology Division, Genome Stability Laboratory, CHU de Québec Research Center, HDQ Pavilion, 2Department of Molecular Biology, Medical Biochemistry, and Pathology, Laval University Cancer Research Center, 3Oncology Division, CHU de Québec Research Center, CHUL Pavilion JoVE 62553 Biology
GST-Hisの精製：全長精製タンパク質を降伏二段階アフィニティー精製プロトコル Ranjan Maity*1, Joris Pauty*1, Jana Krietsch*1, Rémi Buisson1, Marie-Michelle Genois1, Jean-Yves Masson1 1Genome Stability Laboratory, Oncology Axis, Hôtel-Dieu de Québec JoVE 50320 Biology
