In JoVE (1)
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Articles by Jeffery A Hodges in JoVE
Sample Preparation for Single Virion Atomic Force Microscopy and Super-resolution Fluorescence Imaging Jeffery A Hodges1,2, Saveez Saffarian1,2 1Department of Physics & Astronomy, University of Utah, 2Center for Cell and Genome, University of Utah The attachment of virions to a surface is a requirement for single virion imaging by Super-resolution fluorescence imaging or atomic force microscopy (AFM). Here we demonstrate a sample preparation method for controlled adhesion of virions to glass surfaces suitable for use in AFM and super-resolution fluorescence imaging.