Jeffrey C. Edberg Department of Medicine University of Alabama at Birmingham Biography Publications Institution JoVE Articles Jeffrey C. Edberg has not added a biography. If you are Jeffrey C. Edberg and would like to personalize this page please email our Author Liaison for assistance. Publications Lupus Nephritis Susceptibility Loci in Women with Systemic Lupus Erythematosus Journal of the American Society of Nephrology : JASN. Jun, 2014 | Pubmed ID: 24925725 Fcγ Receptor IIIa Single-nucleotide Polymorphisms and Haplotypes Affect Human IgG Binding and Are Associated with Lupus Nephritis in African Americans Arthritis & Rheumatology (Hoboken, N.J.). May, 2014 | Pubmed ID: 24782186 A Polymorphism in TLR2 is Associated with Arterial Thrombosis in a Multi-ethnic SLE Population Arthritis & Rheumatology (Hoboken, N.J.). Feb, 2014 | Pubmed ID: 24578102 End-stage Renal Disease in African Americans with Lupus Nephritis is Associated with APOL1 Arthritis & Rheumatology (Hoboken, N.J.). Feb, 2014 | Pubmed ID: 24504811 FcγRIIIa SNPs and Haplotypes Affect Human IgG Binding and Association with Lupus Nephritis in African Americans Arthritis and Rheumatism. Dec, 2013 | Pubmed ID: 24375423 Allelic-dependent Expression of an Activating Fc Receptor on B Cells Enhances Humoral Immune Responses Science Translational Medicine. Dec, 2013 | Pubmed ID: 24353158 Preferential Binding to Elk-1 by SLE-associated IL10 Risk Allele Upregulates IL10 Expression PLoS Genetics. Oct, 2013 | Pubmed ID: 24130510 ABIN1 Dysfunction As a Genetic Basis for Lupus Nephritis Journal of the American Society of Nephrology : JASN. Nov, 2013 | Pubmed ID: 23970121 PTPN22 Association in Systemic Lupus Erythematosus (SLE) with Respect to Individual Ancestry and Clinical Sub-phenotypes PloS One. 2013 | Pubmed ID: 23950893 Multiple Lupus-associated ITGAM Variants Alter Mac-1 Functions on Neutrophils Arthritis and Rheumatism. Nov, 2013 | Pubmed ID: 23918739 FcγR Gene Copy Number in Kawasaki Disease and Intravenous Immunoglobulin Treatment Response Pharmacogenetics and Genomics. Sep, 2013 | Pubmed ID: 23778324 Genomic Copy Number Variants: Evidence for Association with Antibody Response to Anthrax Vaccine Adsorbed PloS One. 2013 | Pubmed ID: 23741398 Association of Granulomatosis with Polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A Gene Variants: Evidence from Genome-wide Analysis Arthritis and Rheumatism. Sep, 2013 | Pubmed ID: 23740775 Variable Association of Reactive Intermediate Genes with Systemic Lupus Erythematosus in Populations with Different African Ancestry The Journal of Rheumatology. Jun, 2013 | Pubmed ID: 23637325 MicroRNA-3148 Modulates Allelic Expression of Toll-like Receptor 7 Variant Associated with Systemic Lupus Erythematosus PLoS Genetics. 2013 | Pubmed ID: 23468661 Admixture Mapping in Lupus Identifies Multiple Functional Variants Within IFIH1 Associated with Apoptosis, Inflammation, and Autoantibody Production PLoS Genetics. 2013 | Pubmed ID: 23441136 Brief Report: Single-nucleotide Polymorphisms in VKORC1 Are Risk Factors for Systemic Lupus Erythematosus in Asians Arthritis and Rheumatism. Jan, 2013 | Pubmed ID: 23124848 The Unique Cytoplasmic Domain of Human FcγRIIIA Regulates Receptor-mediated Function Journal of Immunology (Baltimore, Md. : 1950). Nov, 2012 | Pubmed ID: 23024279 Fine Mapping of Xq28: Both MECP2 and IRAK1 Contribute to Risk for Systemic Lupus Erythematosus in Multiple Ancestral Groups Annals of the Rheumatic Diseases. Aug, 2012 | Pubmed ID: 22904263 Impact of Genetic Ancestry and Socio-demographic Status on the Clinical Expression of Systemic Lupus Erythematosus in Amerindian-European Populations Arthritis and Rheumatism. Aug, 2012 | Pubmed ID: 22886787 Two Independent Functional Risk Haplotypes in TNIP1 Are Associated with Systemic Lupus Erythematosus Arthritis and Rheumatism. Jul, 2012 | Pubmed ID: 22833143 Genetic Risk Factors for Thrombosis in Systemic Lupus Erythematosus The Journal of Rheumatology. Aug, 2012 | Pubmed ID: 22707612 A Genome-wide Association Study of Host Genetic Determinants of the Antibody Response to Anthrax Vaccine Adsorbed Vaccine. Jul, 2012 | Pubmed ID: 22658931 Role of Activating FcγR Gene Polymorphisms in Kawasaki Disease Susceptibility and Intravenous Immunoglobulin Response Circulation. Cardiovascular Genetics. Jun, 2012 | Pubmed ID: 22565545 Variation in the ICAM1-ICAM4-ICAM5 Locus is Associated with Systemic Lupus Erythematosus Susceptibility in Multiple Ancestries Annals of the Rheumatic Diseases. Nov, 2012 | Pubmed ID: 22523428 Meta-analysis of Genetic Polymorphisms in Granulomatosis with Polyangiitis (Wegener's) Reveals Shared Susceptibility Loci with Rheumatoid Arthritis Arthritis and Rheumatism. Oct, 2012 | Pubmed ID: 22508400 Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 As Susceptibility Loci for Systemic Lupus Erythematosus in a Large-scale Multiracial Replication Study American Journal of Human Genetics. Apr, 2012 | Pubmed ID: 22464253 Association of Single-nucleotide Polymorphisms in CCR6, TAGAP, and TNFAIP3 with Rheumatoid Arthritis in African Americans Arthritis and Rheumatism. May, 2012 | Pubmed ID: 22127930 Analysis of Autosomal Genes Reveals Gene-sex Interactions and Higher Total Genetic Risk in Men with Systemic Lupus Erythematosus Annals of the Rheumatic Diseases. May, 2012 | Pubmed ID: 22110124 IRF5 Haplotypes Demonstrate Diverse Serological Associations Which Predict Serum Interferon Alpha Activity and Explain the Majority of the Genetic Association with Systemic Lupus Erythematosus Annals of the Rheumatic Diseases. Mar, 2012 | Pubmed ID: 22088620 Serine Phosphorylation of FcγRI Cytoplasmic Domain Directs Lipid Raft Localization and Interaction with Protein 4.1G Journal of Leukocyte Biology. Jan, 2012 | Pubmed ID: 22003208 Evidence for Gene-gene Epistatic Interactions Among Susceptibility Loci for Systemic Lupus Erythematosus Arthritis and Rheumatism. Feb, 2012 | Pubmed ID: 21952918 IgA and IgG Antineutrophil Cytoplasmic Antibody Engagement of Fc Receptor Genetic Variants Influences Granulomatosis with Polyangiitis Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011 | Pubmed ID: 22147912 Human FasL Gene is a Target of β-catenin/T-cell Factor Pathway and Complex FasL Haplotypes Alter Promoter Functions PloS One. 2011 | Pubmed ID: 22022540 FAS MRNA Editing in Human Systemic Lupus Erythematosus Human Mutation. Nov, 2011 | Pubmed ID: 21793106 Identification of Novel Genetic Susceptibility Loci in African American Lupus Patients in a Candidate Gene Association Study Arthritis and Rheumatism. Nov, 2011 | Pubmed ID: 21792837 Phenotypic Associations of Genetic Susceptibility Loci in Systemic Lupus Erythematosus Annals of the Rheumatic Diseases. Oct, 2011 | Pubmed ID: 21719445 Association of Genetic Variants in Complement Factor H and Factor H-related Genes with Systemic Lupus Erythematosus Susceptibility PLoS Genetics. May, 2011 | Pubmed ID: 21637784 Functional FCGR2B Gene Variants Influence Intravenous Immunoglobulin Response in Patients with Kawasaki Disease The Journal of Allergy and Clinical Immunology. Sep, 2011 | Pubmed ID: 21601260 Association of PPP2CA Polymorphisms with Systemic Lupus Erythematosus Susceptibility in Multiple Ethnic Groups Arthritis and Rheumatism. Sep, 2011 | Pubmed ID: 21590681 A Higher Degree of LINE-1 Methylation in Peripheral Blood Mononuclear Cells, a One-carbon Nutrient Related Epigenetic Alteration, is Associated with a Lower Risk of Developing Cervical Intraepithelial Neoplasia Nutrition (Burbank, Los Angeles County, Calif.). May, 2011 | Pubmed ID: 21463750 Genetic Analyses of Interferon Pathway-related Genes Reveal Multiple New Loci Associated with Systemic Lupus Erythematosus Arthritis and Rheumatism. Jul, 2011 | Pubmed ID: 21437871 Fine-mapping and Transethnic Genotyping Establish IL2/IL21 Genetic Association with Lupus and Localize This Genetic Effect to IL21 Arthritis and Rheumatism. Jun, 2011 | Pubmed ID: 21425124 Association of a Functional Variant Downstream of TNFAIP3 with Systemic Lupus Erythematosus Nature Genetics. Mar, 2011 | Pubmed ID: 21336280 Identification of a Systemic Lupus Erythematosus Susceptibility Locus at 11p13 Between PDHX and CD44 in a Multiethnic Study American Journal of Human Genetics. Jan, 2011 | Pubmed ID: 21194677 A Higher Degree of Methylation of the HPV 16 E6 Gene is Associated with a Lower Likelihood of Being Diagnosed with Cervical Intraepithelial Neoplasia Cancer. Mar, 2011 | Pubmed ID: 20945322 Most Common Single-nucleotide Polymorphisms Associated with Rheumatoid Arthritis in Persons of European Ancestry Confer Risk of Rheumatoid Arthritis in African Americans Arthritis and Rheumatism. Dec, 2010 | Pubmed ID: 21120996 Alpha₁-antitrypsin Deficiency-related Alleles Z and S and the Risk of Wegener's Granulomatosis Arthritis and Rheumatism. Dec, 2010 | Pubmed ID: 20827781 The Role of Genetic Variation Near Interferon-kappa in Systemic Lupus Erythematosus Journal of Biomedicine & Biotechnology. 2010 | Pubmed ID: 20706608 The Non-muscle Myosin Heavy Chain 9 Gene (MYH9) is Not Associated with Lupus Nephritis in African Americans American Journal of Nephrology. 2010 | Pubmed ID: 20523037 Genetic Variants of STAT4 Associated with Rheumatoid Arthritis in Persons of Asian and European Ancestry Do Not Replicate in African Americans Annals of the Rheumatic Diseases. Apr, 2010 | Pubmed ID: 20237121 Variations in CCL3L Gene Cluster Sequence and Non-specific Gene Copy Numbers BMC Research Notes. 2010 | Pubmed ID: 20233400 Pathways: Strategies for Susceptibility Genes in SLE Autoimmunity Reviews. May, 2010 | Pubmed ID: 20144911 ITGAM Coding Variant (rs1143679) Influences the Risk of Renal Disease, Discoid Rash and Immunological Manifestations in Patients with Systemic Lupus Erythematosus with European Ancestry Annals of the Rheumatic Diseases. Jul, 2010 | Pubmed ID: 19939855 Wegener's Granulomatosis: a Model of Auto-antibodies in Mucosal Autoimmunity Clinical Immunology (Orlando, Fla.). Feb, 2010 | Pubmed ID: 19482554 Retraction: an African Ancestry-specific Allele of CTLA4 Confers Protection Against Rheumatoid Arthritis in African Americans PLoS Genetics. Dec, 2009 | Pubmed ID: 20020059 The FCRL3-169CT Promoter Single-nucleotide Polymorphism, Which is Associated with Systemic Lupus Erythematosus in a Japanese Population, Predicts Expression of Receptor Protein on CD19+ B Cells Arthritis and Rheumatism. Nov, 2009 | Pubmed ID: 19877046 A Large-scale Replication Study Identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 As Risk Loci for Systemic Lupus Erythematosus Nature Genetics. Nov, 2009 | Pubmed ID: 19838195 A Polymorphism Within IL21R Confers Risk for Systemic Lupus Erythematosus Arthritis and Rheumatism. Aug, 2009 | Pubmed ID: 19644854 Variants Within MECP2, a Key Transcription Regulator, Are Associated with Increased Susceptibility to Lupus and Differential Gene Expression in Patients with Systemic Lupus Erythematosus Arthritis and Rheumatism. Apr, 2009 | Pubmed ID: 19333917 An African Ancestry-specific Allele of CTLA4 Confers Protection Against Rheumatoid Arthritis in African Americans PLoS Genetics. Mar, 2009 | Pubmed ID: 19300490 Functional Expression of IgA Receptor FcalphaRI on Human Platelets Journal of Leukocyte Biology. Dec, 2008 | Pubmed ID: 18784345 Features Associated With, and the Impact Of, Hemolytic Anemia in Patients with Systemic Lupus Erythematosus: LX, Results from a Multiethnic Cohort Arthritis and Rheumatism. Sep, 2008 | Pubmed ID: 18759263 Immune Opsonins Modulate BLyS/BAFF Release in a Receptor-specific Fashion Journal of Immunology (Baltimore, Md. : 1950). Jul, 2008 | Pubmed ID: 18606652 Genome-wide Association Scan in Women with Systemic Lupus Erythematosus Identifies Susceptibility Variants in ITGAM, PXK, KIAA1542 and Other Loci Nature Genetics. Feb, 2008 | Pubmed ID: 18204446 Genetic Variation in the CRP Promoter: Association with Systemic Lupus Erythematosus Human Molecular Genetics. Apr, 2008 | Pubmed ID: 18182444 IgA1-secreting Cell Lines from Patients with IgA Nephropathy Produce Aberrantly Glycosylated IgA1 The Journal of Clinical Investigation. Feb, 2008 | Pubmed ID: 18172551 Fc Receptor Genes and the Systemic Lupus Erythematosus Diathesis Autoimmunity. Dec, 2007 | Pubmed ID: 18075791 Variation in the Relative Copy Number of the TLR7 Gene in Patients with Systemic Lupus Erythematosus and Healthy Control Subjects Arthritis and Rheumatism. Oct, 2007 | Pubmed ID: 17907191 Clinical and Genetic Risk Factors for Pneumonia in Systemic Lupus Erythematosus Arthritis and Rheumatism. Aug, 2007 | Pubmed ID: 17665457 FcalphaRI (CD89) Alleles Determine the Proinflammatory Potential of Serum IgA Journal of Immunology (Baltimore, Md. : 1950). Mar, 2007 | Pubmed ID: 17339498 Expression Profile of FcgammaRIIb on Leukocytes and Its Dysregulation in Systemic Lupus Erythematosus Journal of Immunology (Baltimore, Md. : 1950). Mar, 2007 | Pubmed ID: 17312177 Anti-GD3 Monoclonal Antibody Effects on Lymphocytes and Antibody-dependent Cellular Cytotoxicity Cancer Biotherapy & Radiopharmaceuticals. Dec, 2006 | Pubmed ID: 17257070 Association of a Transmembrane Polymorphism of Fcgamma Receptor IIb (FCGR2B) with Systemic Lupus Erythematosus in Taiwanese Patients Arthritis and Rheumatism. Dec, 2006 | Pubmed ID: 17133600 Time to Renal Disease and End-stage Renal Disease in PROFILE: a Multiethnic Lupus Cohort PLoS Medicine. Oct, 2006 | Pubmed ID: 17076550 Differential Gene Expression Modulated by the Cytoplasmic Domain of Fc Gamma RIa (CD64) Alpha-chain Journal of Immunology (Baltimore, Md. : 1950). Nov, 2004 | Pubmed ID: 15528358 The Influence of Genetic Variation in the HLA-DRB1 and LTA-TNF Regions on the Response to Treatment of Early Rheumatoid Arthritis with Methotrexate or Etanercept Arthritis and Rheumatism. Sep, 2004 | Pubmed ID: 15457442 A Promoter Haplotype of the Immunoreceptor Tyrosine-based Inhibitory Motif-bearing FcgammaRIIb Alters Receptor Expression and Associates with Autoimmunity. II. Differential Binding of GATA4 and Yin-Yang1 Transcription Factors and Correlated Receptor Expression and Function Journal of Immunology (Baltimore, Md. : 1950). Jun, 2004 | Pubmed ID: 15153544 A Promoter Haplotype of the Immunoreceptor Tyrosine-based Inhibitory Motif-bearing FcgammaRIIb Alters Receptor Expression and Associates with Autoimmunity. I. Regulatory FCGR2B Polymorphisms and Their Association with Systemic Lupus Erythematosus Journal of Immunology (Baltimore, Md. : 1950). Jun, 2004 | Pubmed ID: 15153543 Fc Gamma RIIIb Allele-sensitive Release of Alpha-defensins: Anti-neutrophil Cytoplasmic Antibody-induced Release of Chemotaxins Journal of Immunology (Baltimore, Md. : 1950). Dec, 2003 | Pubmed ID: 14634123 A Novel Polymorphism in the Fcgamma Receptor IIB (CD32B) Transmembrane Region Alters Receptor Signaling Arthritis and Rheumatism. Nov, 2003 | Pubmed ID: 14613290 A Novel Polymorphic CAAT/enhancer-binding Protein Beta Element in the FasL Gene Promoter Alters Fas Ligand Expression: a Candidate Background Gene in African American Systemic Lupus Erythematosus Patients Journal of Immunology (Baltimore, Md. : 1950). Jan, 2003 | Pubmed ID: 12496392 Diversity and Duplicity: Human FCgamma Receptors in Host Defense and Autoimmunity Immunologic Research. 2002 | Pubmed ID: 12403356 Genetic Linkage and Association of Fcgamma Receptor IIIA (CD16A) on Chromosome 1q23 with Human Systemic Lupus Erythematosus Arthritis and Rheumatism. Aug, 2002 | Pubmed ID: 12209518 The CY Domain of the Fcgamma RIa Alpha-chain (CD64) Alters Gamma-chain Tyrosine-based Signaling and Phagocytosis The Journal of Biological Chemistry. Oct, 2002 | Pubmed ID: 12200451 Differential Regulation of Fcgamma Receptor Isoforms: Implications for Therapeutic Intervention American Journal of Therapeutics. Oct, 1995 | Pubmed ID: 11854786 Нейтрофилов человека Проточная камера Адгезия Анализ Yebin Zhou1, Dennis F. Kucik2,3,4, Alexander J. Szalai5, Jeffrey C. Edberg5 1Genetics and Genomic Sciences Graduate Program, University of Alabama at Birmingham, 2Birmingham Veterans Affairs Medical Center, 3Department of Pathology, University of Alabama at Birmingham, 4Department of Biomedical Engineering, University of Alabama at Birmingham, 5Department of Medicine, University of Alabama at Birmingham JoVE 51410 Immunology and Infection
Нейтрофилов человека Проточная камера Адгезия Анализ Yebin Zhou1, Dennis F. Kucik2,3,4, Alexander J. Szalai5, Jeffrey C. Edberg5 1Genetics and Genomic Sciences Graduate Program, University of Alabama at Birmingham, 2Birmingham Veterans Affairs Medical Center, 3Department of Pathology, University of Alabama at Birmingham, 4Department of Biomedical Engineering, University of Alabama at Birmingham, 5Department of Medicine, University of Alabama at Birmingham JoVE 51410 Immunology and Infection
