Jeffrey E. Lee Department of Laboratory Medicine and Pathobiology University of Toronto Biography Publications Institution JoVE Articles Jeffrey E. Lee has not added a biography. If you are Jeffrey E. Lee and would like to personalize this page please email our Author Liaison for assistance. Publications Journal of the American College of Surgeons. Aug, 2012 | Pubmed ID: 22818108 Risk of Venous Thromboembolism Outweighs Post-hepatectomy Bleeding Complications: Analysis of 5651 National Surgical Quality Improvement Program Patients HPB : the Official Journal of the International Hepato Pancreato Biliary Association. Aug, 2012 | Pubmed ID: 22762398 Overexpression of Protein Phosphatase 4 Correlates with Poor Prognosis in Patients with Stage II Pancreatic Ductal Adenocarcinoma Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Jul, 2012 | Pubmed ID: 22665577 Selective Reoperation for Locally Recurrent or Metastatic Pancreatic Ductal Adenocarcinoma Following Primary Pancreatic Resection Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. May, 2012 | Pubmed ID: 22644446 Journal of the American College of Surgeons. Jul, 2012 | Pubmed ID: 22608401 Response of Borderline Resectable Pancreatic Cancer to Neoadjuvant Therapy is Not Reflected by Radiographic Indicators Cancer. May, 2012 | Pubmed ID: 22605518 HPB : the Official Journal of the International Hepato Pancreato Biliary Association. Jun, 2012 | Pubmed ID: 22568412 Detectable Clonal Mosaicism from Birth to Old Age and Its Relationship to Cancer Nature Genetics. Jun, 2012 | Pubmed ID: 22561516 AJR. American Journal of Roentgenology. Apr, 2012 | Pubmed ID: 22451559 Archives of Surgery (Chicago, Ill. : 1960). Feb, 2012 | Pubmed ID: 22351874 Journal of the American College of Surgeons. Apr, 2012 | Pubmed ID: 22321526 Perineural and Intraneural Invasion in Posttherapy Pancreaticoduodenectomy Specimens Predicts Poor Prognosis in Patients with Pancreatic Ductal Adenocarcinoma The American Journal of Surgical Pathology. Mar, 2012 | Pubmed ID: 22301497 Tumor Invasion of Muscular Vessels Predicts Poor Prognosis in Patients with Pancreatic Ductal Adenocarcinoma Who Have Received Neoadjuvant Therapy and Pancreaticoduodenectomy The American Journal of Surgical Pathology. Apr, 2012 | Pubmed ID: 22301496 Annals of Surgical Oncology. Jun, 2012 | Pubmed ID: 22258816 DNA Repair. Mar, 2012 | Pubmed ID: 22230721 Annals of Surgery. Feb, 2012 | Pubmed ID: 22202581 Melanoma Research. Apr, 2012 | Pubmed ID: 22198560 Archives of Surgery (Chicago, Ill. : 1960). Apr, 2012 | Pubmed ID: 22184134 Histologic Tumor Involvement of Superior Mesenteric Vein/portal Vein Predicts Poor Prognosis in Patients with Stage II Pancreatic Adenocarcinoma Treated with Neoadjuvant Chemoradiation Cancer. Aug, 2012 | Pubmed ID: 22180096 Journal of Virology. Mar, 2012 | Pubmed ID: 22171276 Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Jan, 2012 | Pubmed ID: 22086882 Effect of Neoadjuvant Chemoradiation and Surgical Technique on Recurrence of Localized Pancreatic Cancer Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Jan, 2012 | Pubmed ID: 22065318 Annals of Surgical Oncology. Apr, 2012 | Pubmed ID: 22065191 Pathologic Complete Response to Neoadjuvant Therapy in Patients with Pancreatic Ductal Adenocarcinoma is Associated with a Better Prognosis Annals of Diagnostic Pathology. Jan, 2012 | Pubmed ID: 22050964 Histologic Grading of the Extent of Residual Carcinoma Following Neoadjuvant Chemoradiation in Pancreatic Ductal Adenocarcinoma: a Predictor for Patient Outcome Cancer. Jun, 2012 | Pubmed ID: 22028089 Digestive Diseases and Sciences. Mar, 2012 | Pubmed ID: 21964743 Digestive Diseases and Sciences. Mar, 2012 | Pubmed ID: 21960285 Post-therapy Pathologic Stage and Survival in Patients with Pancreatic Ductal Adenocarcinoma Treated with Neoadjuvant Chemoradiation Cancer. Jan, 2012 | Pubmed ID: 21735446 Achieving Eugastrinemia in MEN1 Patients: Both Duodenal Inspection and Formal Lymph Node Dissection Are Important Surgery. Dec, 2011 | Pubmed ID: 22136834 Nature Genetics. Nov, 2011 | Pubmed ID: 21983787 Genome-wide Association Study Identifies a New Melanoma Susceptibility Locus at 1q21.3 Nature Genetics. Nov, 2011 | Pubmed ID: 21983785 Human Molecular Genetics. Dec, 2011 | Pubmed ID: 21926416 Mapping FACT-melanoma Quality-of-life Scores to EQ-5D Health Utility Weights Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research. Sep-Oct, 2011 | Pubmed ID: 21914512 Surgery. Sep, 2011 | Pubmed ID: 21878230 Phase II Trial of Cetuximab, Gemcitabine, and Oxaliplatin Followed by Chemoradiation with Cetuximab for Locally Advanced (T4) Pancreatic Adenocarcinoma: Correlation of Smad4(Dpc4) Immunostaining with Pattern of Disease Progression Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Aug, 2011 | Pubmed ID: 21709185 Annals of Surgical Oncology. Dec, 2011 | Pubmed ID: 21701927 Human Molecular Genetics. Sep, 2011 | Pubmed ID: 21700618 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2011 | Pubmed ID: 21632855 Human Molecular Genetics. Jul, 2011 | Pubmed ID: 21478494 Journal of the American College of Surgeons. Apr, 2011 | Pubmed ID: 21463807 Annals of Surgical Oncology. Mar, 2011 | Pubmed ID: 21136179 Annals of Surgical Oncology. Apr, 2011 | Pubmed ID: 21104031 Contemporary Diagnostic Imaging Modalities for the Staging and Surveillance of Melanoma Patients: a Meta-analysis Journal of the National Cancer Institute. Jan, 2011 | Pubmed ID: 21081714 Surgery. Apr, 2011 | Pubmed ID: 20947113 European Journal of Cancer (Oxford, England : 1990). Jan, 2011 | Pubmed ID: 20655738 Bulletin of the American College of Surgeons. Aug, 2010 | Pubmed ID: 21462775 Do the Recent American Thyroid Association (ATA) Guidelines Accurately Guide the Timing of Prophylactic Thyroidectomy in MEN2A? Surgery. Dec, 2010 | Pubmed ID: 21134565 Archives of Surgery (Chicago, Ill. : 1960). Nov, 2010 | Pubmed ID: 21079094 The Oncologist. 2010 | Pubmed ID: 21045189 Journal of the American College of Surgeons. Aug, 2010 | Pubmed ID: 20670858 Annals of Surgery. May, 2010 | Pubmed ID: 20395857 Conditional Survival Estimates Improve over 5 Years for Melanoma Survivors with Node-positive Disease Annals of Surgical Oncology. Aug, 2010 | Pubmed ID: 20369298 Prospective Assessment of Postoperative Complications and Associated Costs Following Inguinal Lymph Node Dissection (ILND) in Melanoma Patients Annals of Surgical Oncology. Oct, 2010 | Pubmed ID: 20336388 Conditional Survival Estimates Improve over Time for Patients with Advanced Melanoma: Results from a Population-based Analysis Cancer. May, 2010 | Pubmed ID: 20187100 Serum CA 19-9 As a Marker of Resectability and Survival in Patients with Potentially Resectable Pancreatic Cancer Treated with Neoadjuvant Chemoradiation Annals of Surgical Oncology. Jul, 2010 | Pubmed ID: 20162463 Journal of Translational Medicine. 2010 | Pubmed ID: 20109236 Recurrence of Adrenal Cortical Carcinoma Following Resection: Surgery Alone Can Achieve Results Equal to Surgery Plus Mitotane Annals of Surgical Oncology. Jan, 2010 | Pubmed ID: 19851811 Future Virology. 2009 | Pubmed ID: 20198110 Routine Pre-operative Ultrasonography for Papillary Thyroid Cancer: Effects on Cervical Recurrence Surgery. Dec, 2009 | Pubmed ID: 19958933 Acta Crystallographica. Section D, Biological Crystallography. Nov, 2009 | Pubmed ID: 19923712 Surgery. Dec, 2009 | Pubmed ID: 19879613 Advances in Surgery. 2009 | Pubmed ID: 19845175 Cancer. Dec, 2009 | Pubmed ID: 19827149 Current Opinion in Structural Biology. Aug, 2009 | Pubmed ID: 19559599 Journal of the American College of Surgeons. Jun, 2009 | Pubmed ID: 19476894 Journal of the American College of Surgeons. May, 2009 | Pubmed ID: 19476855 Melanoma Research. Feb, 2009 | Pubmed ID: 19430405 Nature Protocols. 2009 | Pubmed ID: 19373230 Lymph Node Ratio Predicts Disease-specific Survival in Melanoma Patients Cancer. Jun, 2009 | Pubmed ID: 19309746 Archives of Surgery (Chicago, Ill. : 1960). Mar, 2009 | Pubmed ID: 19289659 Long-term Survival After Multidisciplinary Management of Resected Pancreatic Adenocarcinoma Annals of Surgical Oncology. Apr, 2009 | Pubmed ID: 19194760 International Journal of Radiation Oncology, Biology, Physics. Apr, 2009 | Pubmed ID: 18774657 American Journal of Surgery. Dec, 2008 | Pubmed ID: 19095112 Annals of Surgery. Dec, 2008 | Pubmed ID: 19092356 Preoperative Vitamin D Replacement Therapy in Primary Hyperparathyroidism: Safe and Beneficial? Surgery. Dec, 2008 | Pubmed ID: 19040987 Annals of Surgery. Oct, 2008 | Pubmed ID: 18936580 Preoperative Gemcitabine-based Chemoradiation for Patients with Resectable Adenocarcinoma of the Pancreatic Head Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jul, 2008 | Pubmed ID: 18640930 Preoperative Gemcitabine and Cisplatin Followed by Gemcitabine-based Chemoradiation for Resectable Adenocarcinoma of the Pancreatic Head Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jul, 2008 | Pubmed ID: 18640929 Nature. Jul, 2008 | Pubmed ID: 18615077 Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Sep, 2008 | Pubmed ID: 18606982 Fibrin Sealant Does Not Decrease Seroma Output or Time to Drain Removal Following Inguino-femoral Lymph Node Dissection in Melanoma Patients: a Randomized Controlled Trial (NCT00506311) World Journal of Surgical Oncology. 2008 | Pubmed ID: 18564433 Genetic Variants and Haplotypes of the Caspase-8 and Caspase-10 Genes Contribute to Susceptibility to Cutaneous Melanoma Human Mutation. Dec, 2008 | Pubmed ID: 18563783 Parathyroid Exploration in the Reoperative Neck: Improved Preoperative Localization with 4D-computed Tomography Journal of the American College of Surgeons. May, 2008 | Pubmed ID: 18471717 Journal of the American College of Surgeons. May, 2008 | Pubmed ID: 18471707 Cancer. Jun, 2008 | Pubmed ID: 18404695 Cancer. May, 2008 | Pubmed ID: 18383513 Journal of Molecular Biology. Apr, 2008 | Pubmed ID: 18342331 Adjuvant High-dose Interferon for Cutaneous Melanoma is Most Beneficial for Patients with Early Stage III Disease Cancer. May, 2008 | Pubmed ID: 18320602 World Journal of Surgery. May, 2008 | Pubmed ID: 18246389 World Journal of Surgery. May, 2008 | Pubmed ID: 18228092 American Journal of Surgery. Mar, 2008 | Pubmed ID: 18206850 Haplotype and Genotypes of the VDR Gene and Cutaneous Melanoma Risk in Non-Hispanic Whites in Texas: a Case-control Study International Journal of Cancer. Journal International Du Cancer. May, 2008 | Pubmed ID: 18183598 Polymorphisms of TP53 Arg72Pro, but Not P73 G4C14>A4TA4 and P21 Ser31Arg, Contribute to Risk of Cutaneous Melanoma The Journal of Investigative Dermatology. Jun, 2008 | Pubmed ID: 18049450 Journal of Molecular Biology. Jan, 2008 | Pubmed ID: 18005986 Annals of Surgical Oncology. Jan, 2008 | Pubmed ID: 17963006 Surgery. Dec, 2007 | Pubmed ID: 18063070 The New England Journal of Medicine. Sep, 2007 | Pubmed ID: 17891836 Pelvic Lymph Node Dissection is Beneficial in Subsets of Patients with Node-positive Melanoma Annals of Surgical Oncology. Oct, 2007 | Pubmed ID: 17671814 Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. Jul-Aug, 2007 | Pubmed ID: 17669708 Journal of the American College of Surgeons. Aug, 2007 | Pubmed ID: 17660070 Impact of Resection Status on Pattern of Failure and Survival After Pancreaticoduodenectomy for Pancreatic Adenocarcinoma Annals of Surgery. Jul, 2007 | Pubmed ID: 17592291 Cost Effectiveness of Adjuvant Interferon in Node-positive Melanoma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2007 | Pubmed ID: 17557957 Hematology/oncology Clinics of North America. Jun, 2007 | Pubmed ID: 17548037 The Learning Curve in Pancreatic Surgery Surgery. May, 2007 | Pubmed ID: 17511115 The Learning Curve in Pancreatic Surgery Surgery. Apr, 2007 | Pubmed ID: 17383522 Polymorphisms of the Neuronal and Inducible Nitric Oxide Synthase Genes and the Risk of Cutaneous Melanoma: a Case-control Study Cancer. Apr, 2007 | Pubmed ID: 17328085 Journal of the American College of Surgeons. Mar, 2007 | Pubmed ID: 17324767 Genetic Variants of the Vitamin D Receptor Gene Alter Risk of Cutaneous Melanoma The Journal of Investigative Dermatology. Feb, 2007 | Pubmed ID: 16990805 Improved Preoperative Planning for Directed Parathyroidectomy with 4-dimensional Computed Tomography Surgery. Dec, 2006 | Pubmed ID: 17188140 Polymorphisms in the DNA Repair Genes XPC, XPD, and XPG and Risk of Cutaneous Melanoma: a Case-control Analysis Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Dec, 2006 | Pubmed ID: 17164380 Cancer. Dec, 2006 | Pubmed ID: 17063497 Ethnic Differences Among Patients with Cutaneous Melanoma Archives of Internal Medicine. Sep, 2006 | Pubmed ID: 17000949 Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Sep, 2006 | Pubmed ID: 16943537 Surgical Oncology Clinics of North America. Jul, 2006 | Pubmed ID: 16882496 Borderline Resectable Pancreatic Cancer: Definitions, Management, and Role of Preoperative Therapy Annals of Surgical Oncology. Aug, 2006 | Pubmed ID: 16865597 Invasive Squamous Cell Carcinoma of the Skin: Defining a High-risk Group Annals of Surgical Oncology. Jul, 2006 | Pubmed ID: 16788750 Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2006 | Pubmed ID: 16782925 World Journal of Surgery. May, 2006 | Pubmed ID: 16680581 Surgery. Apr, 2006 | Pubmed ID: 16627063 Genetic Variants of the ADPRT, XRCC1 and APE1 Genes and Risk of Cutaneous Melanoma Carcinogenesis. Sep, 2006 | Pubmed ID: 16621887 Abdominal Visceral Lesions in Von Hippel-Lindau Disease: Incidence and Clinical Behavior of Pancreatic and Adrenal Lesions at a Single Center World Journal of Surgery. May, 2006 | Pubmed ID: 16617420 Metastatic Melanoma to Lymph Nodes in Patients with Unknown Primary Sites Cancer. May, 2006 | Pubmed ID: 16568458 Best Practice & Research. Clinical Gastroenterology. Apr, 2006 | Pubmed ID: 16549332 Polymorphisms of the FAS and FAS Ligand Genes Associated with Risk of Cutaneous Malignant Melanoma Pharmacogenetics and Genomics. Apr, 2006 | Pubmed ID: 16538172 Annals of Surgical Oncology. Apr, 2006 | Pubmed ID: 16523362 Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2006 | Pubmed ID: 16505434 Cancer. Feb, 2006 | Pubmed ID: 16411225 International Journal of Radiation Oncology, Biology, Physics. Jan, 2006 | Pubmed ID: 16182463 Journal of the National Cancer Institute. Dec, 2005 | Pubmed ID: 16368944 Surgery. Dec, 2005 | Pubmed ID: 16360394 Carcinoid Tumors of the Duodenum Surgery. Dec, 2005 | Pubmed ID: 16360380 Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Nov, 2005 | Pubmed ID: 16269380 Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Sep, 2005 | Pubmed ID: 16135473 Biochemistry. Sep, 2005 | Pubmed ID: 16128565 Journal of Molecular Biology. Sep, 2005 | Pubmed ID: 16109423 Biochemistry. Aug, 2005 | Pubmed ID: 16101288 Thyroid : Official Journal of the American Thyroid Association. Jun, 2005 | Pubmed ID: 16029119 Annals of Surgical Oncology. Aug, 2005 | Pubmed ID: 16021533 Journal of the National Comprehensive Cancer Network : JNCCN. May, 2005 | Pubmed ID: 16002007 Archives of Surgery (Chicago, Ill. : 1960). Jun, 2005 | Pubmed ID: 15967906 Head & Neck. Aug, 2005 | Pubmed ID: 15952196 Annals of Surgical Oncology. Jul, 2005 | Pubmed ID: 15952075 Archives of Surgery (Chicago, Ill. : 1960). Apr, 2005 | Pubmed ID: 15841561 The Journal of Biological Chemistry. May, 2005 | Pubmed ID: 15749708 The Journal of Biological Chemistry. May, 2005 | Pubmed ID: 15746096 Journal of Surgical Oncology. Mar, 2005 | Pubmed ID: 15719379 Surgery. Dec, 2004 | Pubmed ID: 15657574 Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Dec, 2004 | Pubmed ID: 15585381 Annals of Surgical Oncology. Dec, 2004 | Pubmed ID: 15576833 Cancer Research. Aug, 2004 | Pubmed ID: 15289358 A Convenient and General Expression Platform for the Production of Secreted Proteins from Human Cells Halil Aydin*1, Farshad C. Azimi*1, Jonathan D. Cook*1, Jeffrey E. Lee1 1Department of Laboratory Medicine and Pathobiology, University of Toronto JoVE 4041 Biology
A Convenient and General Expression Platform for the Production of Secreted Proteins from Human Cells Halil Aydin*1, Farshad C. Azimi*1, Jonathan D. Cook*1, Jeffrey E. Lee1 1Department of Laboratory Medicine and Pathobiology, University of Toronto JoVE 4041 Biology