Jennifer E. Van Eyk

Publications

• MitoPlex: A Targeted Multiple Reaction Monitoring Assay for Quantification of a Curated Set of Mitochondrial Proteins
  Journal of Molecular and Cellular Cardiology. Mar, 2020  |   Pubmed ID: 32234390
• Identification of Putative Early Atherosclerosis Biomarkers by Unsupervised Deconvolution of Heterogeneous Vascular Proteomes
  Journal of Proteome Research. Apr, 2020  |   Pubmed ID: 32202800
• A Dual Workflow to Improve the Proteomic Coverage in Plasma Using Data-Independent Acquisition-MS
  Journal of Proteome Research. Mar, 2020  |   Pubmed ID: 32176508
• ACE Overexpression in Myeloid Cells Increases Oxidative Metabolism and Cellular ATP
  The Journal of Biological Chemistry. Jan, 2020  |   Pubmed ID: 31871049
• Vascular Biomarkers and Digital Ulcerations in Systemic Sclerosis: Results from a Randomized Controlled Trial of Oral Treprostinil (DISTOL-1)
  Clinical Rheumatology. Apr, 2020  |   Pubmed ID: 31858338
• Neuron-generated Thrombin Induces a Protective Astrocyte Response Via Protease Activated Receptors
  Glia. 02, 2020  |   Pubmed ID: 31453648
• Mining the Proteome Associated with Rheumatic and Autoimmune Diseases
  Journal of Proteome Research. 12, 2019  |   Pubmed ID: 31599600
• Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 3.0
  Journal of Proteome Research. 12, 2019  |   Pubmed ID: 31599596
• A Protocol Integrating Remote Patient Monitoring Patient Reported Outcomes and Cardiovascular Biomarkers
  NPJ Digital Medicine. 2019  |   Pubmed ID: 31508495
• Progress on Identifying and Characterizing the Human Proteome: 2019 Metrics from the HUPO Human Proteome Project
  Journal of Proteome Research. 12, 2019  |   Pubmed ID: 31430157
• Serum NfL (Neurofilament Light Chain) Levels and Incident Stroke in Adults With Diabetes Mellitus
  Stroke. 07, 2019  |   Pubmed ID: 31138085
• Multipotent Fetal-derived Cdx2 Cells from Placenta Regenerate the Heart
  Proceedings of the National Academy of Sciences of the United States of America. 06, 2019  |   Pubmed ID: 31109997
• Mapping Citrullinated Sites in Multiple Organs of Mice Using Hypercitrullinated Library
  Journal of Proteome Research. 05, 2019  |   Pubmed ID: 30990720
• Acute Neuropathological Consequences of Short-term Mechanical Ventilation in Wild-type and Alzheimer's Disease Mice
  Critical Care (London, England). 02, 2019  |   Pubmed ID: 30795776
• PKG1-modified TSC2 Regulates MTORC1 Activity to Counter Adverse Cardiac Stress
  Nature. 02, 2019  |   Pubmed ID: 30700906
• In Vitro and In Vivo Proteomic Comparison of Human Neural Progenitor Cell-Induced Photoreceptor Survival
  Proteomics. 02, 2019  |   Pubmed ID: 30515959
• Precision Medicine: Role of Proteomics in Changing Clinical Management and Care
  Journal of Proteome Research. 01, 2019  |   Pubmed ID: 30296097
• Precision Medicine
  Circulation. 11, 2018  |   Pubmed ID: 30571512
• Cardiac Troponins May Be Irreversibly Modified by Glycation: Novel Potential Mechanisms of Cardiac Performance Modulation
  Scientific Reports. 10, 2018  |   Pubmed ID: 30382112
• Diabetes with Heart Failure Increases Methylglyoxal Modifications in the Sarcomere, Which Inhibit Function
  JCI Insight. 10, 2018  |   Pubmed ID: 30333300
• Identifying High-Priority Proteins Across the Human Diseasome Using Semantic Similarity
  Journal of Proteome Research. 12, 2018  |   Pubmed ID: 30256117
• Sex Differences in Ischemic Heart Disease and Heart Failure Biomarkers
  Biology of Sex Differences. 09, 2018  |   Pubmed ID: 30223899
• Phospho-Proteomic Analysis of Cardiac Dyssynchrony and Resynchronization Therapy
  Proteomics. Aug, 2018  |   Pubmed ID: 30129105
• Progress on Identifying and Characterizing the Human Proteome: 2018 Metrics from the HUPO Human Proteome Project
  Journal of Proteome Research. Aug, 2018  |   Pubmed ID: 30099871
• Proteomics Reveals Rictor As a Non-Canonical TGFB Signaling Target During Aneurysm Progression in Marfan Mice
  American Journal of Physiology. Heart and Circulatory Physiology. Jul, 2018  |   Pubmed ID: 30004239
• Proteomic Architecture of Human Coronary and Aortic Atherosclerosis
  Circulation. Jun, 2018  |   Pubmed ID: 29915101
• Evaluating Utility and Compliance in a Patient-based EHealth Study Using Continuous-time Heart Rate and Activity Trackers
  Journal of the American Medical Informatics Association : JAMIA. May, 2018  |   Pubmed ID: 29850807
• Precision Profiling of the Cardiovascular Post-Translationally Modified Proteome: Where There Is a Will, There Is a Way
  Circulation Research. Apr, 2018  |   Pubmed ID: 29700069
• Newt Cells Secrete Extracellular Vesicles with Therapeutic Bioactivity in Mammalian Cardiomyocytes
  Journal of Extracellular Vesicles. 2018  |   Pubmed ID: 29696078
• A Proteomics Workflow for Dual Labeling Biotin Switch Assay to Detect and Quantify Protein S-Nitroylation
  Methods in Molecular Biology (Clifton, N.J.). 2018  |   Pubmed ID: 29600453
• Genome-wide Analyses Identify KIF5A As a Novel ALS Gene
  Neuron. Mar, 2018  |   Pubmed ID: 29566793
• Protein -Nitrosylation Controls Glycogen Synthase Kinase 3β Function Independent of Its Phosphorylation State
  Circulation Research. May, 2018  |   Pubmed ID: 29563102
• Desmin Phosphorylation Triggers Preamyloid Oligomers Formation and Myocyte Dysfunction in Acquired Heart Failure
  Circulation Research. May, 2018  |   Pubmed ID: 29483093
• How Many Human Proteoforms Are There?
  Nature Chemical Biology. Feb, 2018  |   Pubmed ID: 29443976
• Molecular Profile of Priapism Associated with Low Nitric Oxide Bioavailability
  Journal of Proteome Research. 03, 2018  |   Pubmed ID: 29394072
• Guidelines for Experimental Models of Myocardial Ischemia and Infarction
  American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2018  |   Pubmed ID: 29351451
• The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations
  Cell Systems. Jan, 2018  |   Pubmed ID: 29199020
• Association of Quantitative Metastatic Lymph Node Burden With Survival in Hypopharyngeal and Laryngeal Cancer
  JAMA Oncology. Jul, 2018  |   Pubmed ID: 29192305
• Highly Reproducible Automated Proteomics Sample Preparation Workflow for Quantitative Mass Spectrometry
  Journal of Proteome Research. 01, 2018  |   Pubmed ID: 29083196
• Transient Receptor Potential Channel 6 Regulates Abnormal Cardiac S-nitrosylation in Duchenne Muscular Dystrophy
  Proceedings of the National Academy of Sciences of the United States of America. 12, 2017  |   Pubmed ID: 29187535
• Metastatic Lymph Node Burden and Survival in Oral Cavity Cancer
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Nov, 2017  |   Pubmed ID: 28880746
• Advances in Quantifying Apolipoproteins Using LC-MS/MS Technology: Implications for the Clinic
  Expert Review of Proteomics. 10, 2017  |   Pubmed ID: 28870113
• Profiling B-Type Natriuretic Peptide Cleavage Peptidoforms in Human Plasma by Capillary Electrophoresis with Electrospray Ionization Mass Spectrometry
  Journal of Proteome Research. Dec, 2017  |   Pubmed ID: 28861997
• Exploring Ribosome Composition and Newly Synthesized Proteins Through Proteomics and Potential Biomedical Applications
  Expert Review of Proteomics. 06, 2017  |   Pubmed ID: 28532181
• Mapping Biological Networks from Quantitative Data-Independent Acquisition Mass Spectrometry: Data to Knowledge Pipelines
  Methods in Molecular Biology (Clifton, N.J.). 2017  |   Pubmed ID: 28150249
• A Roadmap to Successful Clinical Proteomics
  Clinical Chemistry. Jan, 2017  |   Pubmed ID: 27864386
• Extracellular Matrix Downregulation in the Drosophila Heart Preserves Contractile Function and Improves Lifespan
  Matrix Biology : Journal of the International Society for Matrix Biology. Oct, 2017  |   Pubmed ID: 27793636
• A Novel, Multiplexed Targeted Mass Spectrometry Assay for Quantification of Complement Factor H (CFH) Variants and CFH-related Proteins 1-5 in Human Plasma
  Proteomics. Mar, 2017  |   Pubmed ID: 27647805
• The Proteome of Normal Human Retrobulbar Optic Nerve and Sclera
  Proteomics. 10, 2016  |   Pubmed ID: 27538499
• Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 2.1
  Journal of Proteome Research. 11, 2016  |   Pubmed ID: 27490519
• Effect of Peptide Assay Library Size and Composition in Targeted Data-independent Acquisition-MS Analyses
  Proteomics. 08, 2016  |   Pubmed ID: 27432805
• Data-Driven Approach To Determine Popular Proteins for Targeted Proteomics Translation of Six Organ Systems
  Journal of Proteome Research. 11, 2016  |   Pubmed ID: 27356587
• Discordant Signaling and Autophagy Response to Fasting in Hearts of Obese Mice: Implications for Ischemia Tolerance
  American Journal of Physiology. Heart and Circulatory Physiology. 07, 2016  |   Pubmed ID: 27199111
• Profilin Modulates Sarcomeric Organization and Mediates Cardiomyocyte Hypertrophy
  Cardiovascular Research. May, 2016  |   Pubmed ID: 26956799
• Methods for SWATH™: Data Independent Acquisition on TripleTOF Mass Spectrometers
  Methods in Molecular Biology (Clifton, N.J.). 2016  |   Pubmed ID: 26867750
• Multiple and Selective Reaction Monitoring Using Triple Quadrupole Mass Spectrometer: Preclinical Large Cohort Analysis
  Methods in Molecular Biology (Clifton, N.J.). 2016  |   Pubmed ID: 26867749
• Defining the Proteome of Human Iris, Ciliary Body, Retinal Pigment Epithelium, and Choroid
  Proteomics. Apr, 2016  |   Pubmed ID: 26834087
• Recommendations for the Generation, Quantification, Storage, and Handling of Peptides Used for Mass Spectrometry-Based Assays
  Clinical Chemistry. Jan, 2016  |   Pubmed ID: 26719571
• Protein Kinase G Signaling in Cardiac Pathophysiology: Impact of Proteomics on Clinical Trials
  Proteomics. Mar, 2016  |   Pubmed ID: 26670943
• An Empirical Approach to Signature Peptide Choice for Selected Reaction Monitoring: Quantification of Uromodulin in Urine
  Clinical Chemistry. Jan, 2016  |   Pubmed ID: 26589548
• A Novel Phosphorylation Site at Ser130 Adjacent to the Pseudosubstrate Domain Contributes to the Activation of Protein Kinase C-δ
  The Biochemical Journal. Feb, 2016  |   Pubmed ID: 26546672
• Pacemaker-induced Transient Asynchrony Suppresses Heart Failure Progression
  Science Translational Medicine. Dec, 2015  |   Pubmed ID: 26702095
• Dual Labeling Biotin Switch Assay to Reduce Bias Derived From Different Cysteine Subpopulations: A Method to Maximize S-Nitrosylation Detection
  Circulation Research. Oct, 2015  |   Pubmed ID: 26338901
• Biomarkers of Pulmonary Hypertension in Patients with Scleroderma: a Case-control Study
  Arthritis Research & Therapy. Aug, 2015  |   Pubmed ID: 26245195
• Identification of a Set of Conserved Eukaryotic Internal Retention Time Standards for Data-independent Acquisition Mass Spectrometry
  Molecular & Cellular Proteomics : MCP. Oct, 2015  |   Pubmed ID: 26199342
• Priorities and Trends in the Study of Proteins in Eye Research, 1924-2014
  Proteomics. Clinical Applications. Dec, 2015  |   Pubmed ID: 26123431
• Citrullination of Myofilament Proteins in Heart Failure
  Cardiovascular Research. Nov, 2015  |   Pubmed ID: 26113265
• Vinculin Network-mediated Cytoskeletal Remodeling Regulates Contractile Function in the Aging Heart
  Science Translational Medicine. Jun, 2015  |   Pubmed ID: 26084806
• Identification of Glycoproteins Containing Specific Glycans Using a Lectin-chemical Method
  Analytical Chemistry. 2015  |   Pubmed ID: 25837443
• Universal Therapeutic Targeting of Age-related Protein Quality Control System Dysfunction in Chronic Diseases?
  Trends in Cardiovascular Medicine. Apr, 2015  |   Pubmed ID: 25802225
• A Novel Phosphorylation Site, Serine 199, in the C-terminus of Cardiac Troponin I Regulates Calcium Sensitivity and Susceptibility to Calpain-induced Proteolysis
  Journal of Molecular and Cellular Cardiology. May, 2015  |   Pubmed ID: 25771144
• Cross-Disciplinary Biomarkers Research: Lessons Learned by the CKD Biomarkers Consortium
  Clinical Journal of the American Society of Nephrology : CJASN. May, 2015  |   Pubmed ID: 25739849
• Assessing Amide Proton Transfer (APT) MRI Contrast Origins in 9 L Gliosarcoma in the Rat Brain Using Proteomic Analysis
  Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Aug, 2015  |   Pubmed ID: 25622812
• Emerging Proteomic Technologies for Elucidating Context-dependent Cellular Signaling Events: A Big Challenge of Tiny Proportions
  Proteomics. May, 2015  |   Pubmed ID: 25545106
• The Proteome of Human Retina
  Proteomics. Feb, 2015  |   Pubmed ID: 25407473
• Identification of Cardiac Myofilament Protein Isoforms Using Multiple Mass Spectrometry Based Approaches
  Proteomics. Clinical Applications. Aug, 2014  |   Pubmed ID: 24974818
• Redox Signaling and Protein Phosphorylation in Mitochondria: Progress and Prospects
  Journal of Bioenergetics and Biomembranes. Apr, 2009  |   Pubmed ID: 19440831