Jenny K.W. Lam

Publications

• Effect of Formulation and Inhaler Parameters on the Dispersion of Spray Freeze Dried Voriconazole Particles
  International Journal of Pharmaceutics. Jun, 2020  |   Pubmed ID: 32445908
• Modification of KL4 Peptide Revealed the Importance of Alpha-Helical Structure for Efficient Small Interfering RNA Delivery
  Nucleic Acid Therapeutics. Apr, 2020  |   Pubmed ID: 32352853
• High SiRNA Loading Powder for Inhalation Prepared by Co-spray Drying with Human Serum Albumin
  International Journal of Pharmaceutics. Dec, 2019  |   Pubmed ID: 31678379
• Effective MRNA Pulmonary Delivery by Dry Powder Formulation of PEGylated Synthetic KL4 Peptide
  Journal of Controlled Release : Official Journal of the Controlled Release Society. 11, 2019  |   Pubmed ID: 31629037
• Porous and Highly Dispersible Voriconazole Dry Powders Produced by Spray Freeze Drying for Pulmonary Delivery with Efficient Lung Deposition
  International Journal of Pharmaceutics. Apr, 2019  |   Pubmed ID: 30731259
• Spray Freeze Drying of Small Nucleic Acids As Inhaled Powder for Pulmonary Delivery
  Asian Journal of Pharmaceutical Sciences. Mar, 2018  |   Pubmed ID: 32104389
• Using Two-fluid Nozzle for Spray Freeze Drying to Produce Porous Powder Formulation of Naked SiRNA for Inhalation
  International Journal of Pharmaceutics. Dec, 2018  |   Pubmed ID: 30244146
• Rifampin- or Capreomycin-Induced Remodeling of the Mycolic Acid Layer Is Mitigated in Synergistic Combinations with Cationic Antimicrobial Peptides
  MSphere. 07, 2018  |   Pubmed ID: 30021876
• Synthesis, Structure⁻Activity Relationships and In Vitro Toxicity Profile of Lactose-Based Fatty Acid Monoesters As Possible Drug Permeability Enhancers
  Pharmaceutics. Jul, 2018  |   Pubmed ID: 29970849
• From Pulmonary Surfactant, Synthetic KL4 Peptide As Effective SiRNA Delivery Vector for Pulmonary Delivery
  Molecular Pharmaceutics. 12, 2017  |   Pubmed ID: 29121767
• Inhaled Powder Formulation of Naked SiRNA Using Spray Drying Technology with L-leucine As Dispersion Enhancer
  International Journal of Pharmaceutics. Sep, 2017  |   Pubmed ID: 28720537
• Water-in-Oil Microemulsions for Protein Delivery: Loading Optimization and Stability
  Current Pharmaceutical Biotechnology. 2017  |   Pubmed ID: 28482785
• Steroidogenic Effect of Erxian Decoction for Relieving Menopause Via the P-Akt/PKB Pathway in Vitro and in Vivo
  Journal of Ethnopharmacology. Jan, 2017  |   Pubmed ID: 27871904
• Delivery of RNAi Therapeutics to the Airways-From Bench to Bedside
  Molecules (Basel, Switzerland). Sep, 2016  |   Pubmed ID: 27657028
• Incorporation of a Nuclear Localization Signal in PH Responsive LAH4-L1 Peptide Enhances Transfection and Nuclear Uptake of Plasmid DNA
  Molecular Pharmaceutics. 09, 2016  |   Pubmed ID: 27458925
• Potential and Development of Inhaled RNAi Therapeutics for the Treatment of Pulmonary Tuberculosis
  Advanced Drug Delivery Reviews. 07, 2016  |   Pubmed ID: 27108702
• SiRNA Versus MiRNA As Therapeutics for Gene Silencing
  Molecular Therapy. Nucleic Acids. Sep, 2015  |   Pubmed ID: 26372022
• Dry Powder Formulation of Plasmid DNA and SiRNA for Inhalation
  Current Pharmaceutical Design. 2015  |   Pubmed ID: 26290202
• Inhalable Spray-dried Formulation of D-LAK Antimicrobial Peptides Targeting Tuberculosis
  International Journal of Pharmaceutics. Aug, 2015  |   Pubmed ID: 26151107
• Oleanolic Acid Loaded PEGylated PLA and PLGA Nanoparticles with Enhanced Cytotoxic Activity Against Cancer Cells
  Molecular Pharmaceutics. Jun, 2015  |   Pubmed ID: 25881668
• Inhalable Dry Powder Formulations of SiRNA and PH-responsive Peptides with Antiviral Activity Against H1N1 Influenza Virus
  Molecular Pharmaceutics. Mar, 2015  |   Pubmed ID: 25599953
• Cationic Amphipathic D-enantiomeric Antimicrobial Peptides with in Vitro and Ex Vivo Activity Against Drug-resistant Mycobacterium Tuberculosis
  Tuberculosis (Edinburgh, Scotland). Dec, 2014  |   Pubmed ID: 25154927
• Intranasal DNA Vaccine for Protection Against Respiratory Infectious Diseases: The Delivery Perspectives
  Pharmaceutics. Jul, 2014  |   Pubmed ID: 25014738
• Oral Transmucosal Drug Delivery for Pediatric Use
  Advanced Drug Delivery Reviews. Jun, 2014  |   Pubmed ID: 23999459
• Formulation of PH Responsive Peptides As Inhalable Dry Powders for Pulmonary Delivery of Nucleic Acids
  European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V. Jan, 2014  |   Pubmed ID: 23702276
• Manipulating the PH Response of 2,3-diaminopropionic Acid Rich Peptides to Mediate Highly Effective Gene Silencing with Low-toxicity
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2013  |   Pubmed ID: 24144917
• Western Blot Evaluation of SiRNA Delivery by PH-Responsive Peptides
  Methods in Molecular Biology (Clifton, N.J.). 2013  |   Pubmed ID: 23436406
• Conformational Flexibility Determines Selectivity and Antibacterial, Antiplasmodial, and Anticancer Potency of Cationic α-helical Peptides
  The Journal of Biological Chemistry. Oct, 2012  |   Pubmed ID: 22869378
• Effective Endogenous Gene Silencing Mediated by PH Responsive Peptides Proceeds Via Multiple Pathways
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Mar, 2012  |   Pubmed ID: 22138072
• Pulmonary Delivery of Therapeutic SiRNA
  Advanced Drug Delivery Reviews. Jan, 2012  |   Pubmed ID: 21356260
• The Involvement of Microtubules and Actin Filaments in the Intracellular Transport of Non-viral Gene Delivery System
  Journal of Drug Targeting. Jan, 2011  |   Pubmed ID: 20353287