Jeremy Nathans Department of Molecular Biology and Genetics Howard Hughes Medical Institute, Johns Hopkins University School of Medicine Biography Publications Institution JoVE Articles Jeremy Nathans has not added a biography. If you are Jeremy Nathans and would like to personalize this page please email our Author Liaison for assistance. Publications Complete Morphologies of Basal Forebrain Cholinergic Neurons in the Mouse ELife. 2014 | Pubmed ID: 24894464 Frizzled3 is Required for the Development of Multiple Axon Tracts in the Mouse Central Nervous System Proceedings of the National Academy of Sciences of the United States of America. May, 2014 | Pubmed ID: 24799694 Cellular Resolution Maps of X Chromosome Inactivation: Implications for Neural Development, Function, and Disease Neuron. Jan, 2014 | Pubmed ID: 24411735 Frizzled3 Controls Axonal Development in Distinct Populations of Cranial and Spinal Motor Neurons ELife. 2013 | Pubmed ID: 24347548 Endothelin-2 Signaling in the Neural Retina Promotes the Endothelial Tip Cell State and Inhibits Angiogenesis Proceedings of the National Academy of Sciences of the United States of America. Oct, 2013 | Pubmed ID: 24043815 How to Draw the Line in Biomedical Research ELife. 2013 | Pubmed ID: 23538852 Responses of Hair Follicle-associated Structures to Loss of Planar Cell Polarity Signaling Proceedings of the National Academy of Sciences of the United States of America. Mar, 2013 | Pubmed ID: 23431170 Morphologic Diversity of Cutaneous Sensory Afferents Revealed by Genetically Directed Sparse Labeling ELife. 2012 | Pubmed ID: 23256042 Norrin/Frizzled4 Signaling in Retinal Vascular Development and Blood Brain Barrier Plasticity Cell. Dec, 2012 | Pubmed ID: 23217714 Frizzled 2 and Frizzled 7 Function Redundantly in Convergent Extension and Closure of the Ventricular Septum and Palate: Evidence for a Network of Interacting Genes Development (Cambridge, England). Dec, 2012 | Pubmed ID: 23095888 Combinatorial Expression of Brn3 Transcription Factors in Somatosensory Neurons: Genetic and Morphologic Analysis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2012 | Pubmed ID: 22262898 Signaling by Sensory Receptors Cold Spring Harbor Perspectives in Biology. Jan, 2012 | Pubmed ID: 22110046 Class 5 Transmembrane Semaphorins Control Selective Mammalian Retinal Lamination and Function Neuron. Aug, 2011 | Pubmed ID: 21835343 Preclinical Assessment of CNS Drug Action Using Eye Movements in Mice The Journal of Clinical Investigation. Sep, 2011 | Pubmed ID: 21821912 Genetic Mosaic Analysis Reveals a Major Role for Frizzled 4 and Frizzled 8 in Controlling Ureteric Growth in the Developing Kidney Development (Cambridge, England). Mar, 2011 | Pubmed ID: 21343368 Expression of the Norrie Disease Gene (Ndp) in Developing and Adult Mouse Eye, Ear, and Brain Gene Expression Patterns : GEP. Jan-Feb, 2011 | Pubmed ID: 21055480 Morphologies of Mouse Retinal Ganglion Cells Expressing Transcription Factors Brn3a, Brn3b, and Brn3c: Analysis of Wild Type and Mutant Cells Using Genetically-directed Sparse Labeling Vision Research. Jan, 2011 | Pubmed ID: 20826176 An MRI-based Atlas and Database of the Developing Mouse Brain NeuroImage. Jan, 2011 | Pubmed ID: 20656042 China's Plan Flawed but Courageous Science (New York, N.Y.). Dec, 2010 | Pubmed ID: 21163997 When Whorls Collide: the Development of Hair Patterns in Frizzled 6 Mutant Mice Development (Cambridge, England). Dec, 2010 | Pubmed ID: 21062866 Frizzled 1 and Frizzled 2 Genes Function in Palate, Ventricular Septum and Neural Tube Closure: General Implications for Tissue Fusion Processes Development (Cambridge, England). Nov, 2010 | Pubmed ID: 20940229 The Norrin/Frizzled4 Signaling Pathway in Retinal Vascular Development and Disease Trends in Molecular Medicine. Sep, 2010 | Pubmed ID: 20688566 New Mouse Lines for the Analysis of Neuronal Morphology Using CreER(T)/loxP-directed Sparse Labeling PloS One. 2009 | Pubmed ID: 19924248 Norrin, Frizzled-4, and Lrp5 Signaling in Endothelial Cells Controls a Genetic Program for Retinal Vascularization Cell. Oct, 2009 | Pubmed ID: 19837032 The Evolution of Primate Color Vision Scientific American. Apr, 2009 | Pubmed ID: 19363921 Distinct Roles of Transcription Factors Brn3a and Brn3b in Controlling the Development, Morphology, and Function of Retinal Ganglion Cells Neuron. Mar, 2009 | Pubmed ID: 19323995 Genetically-directed, Cell Type-specific Sparse Labeling for the Analysis of Neuronal Morphology PloS One. 2008 | Pubmed ID: 19116659 An Essential Role for Frizzled 5 in Mammalian Ocular Development Development (Cambridge, England). Nov, 2008 | Pubmed ID: 18832390 The Genomic Response of the Retinal Pigment Epithelium to Light Damage and Retinal Detachment The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2008 | Pubmed ID: 18815272 An Essential Role for Frizzled5 in Neuronal Survival in the Parafascicular Nucleus of the Thalamus The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2008 | Pubmed ID: 18509025 The Optokinetic Reflex As a Tool for Quantitative Analyses of Nervous System Function in Mice: Application to Genetic and Drug-induced Variation PloS One. 2008 | Pubmed ID: 18446207 Estrogen-related Receptor Beta/NR3B2 Controls Epithelial Cell Fate and Endolymph Production by the Stria Vascularis Developmental Cell. Sep, 2007 | Pubmed ID: 17765677 Genetic Ablation of Cone Photoreceptors Eliminates Retinal Folds in the Retinal Degeneration 7 (rd7) Mouse Investigative Ophthalmology & Visual Science. Jun, 2007 | Pubmed ID: 17525215 Emergence of Novel Color Vision in Mice Engineered to Express a Human Cone Photopigment Science (New York, N.Y.). Mar, 2007 | Pubmed ID: 17379811 Tissue/planar Cell Polarity in Vertebrates: New Insights and New Questions Development (Cambridge, England). Feb, 2007 | Pubmed ID: 17259302 Mutational Analysis of Norrin-Frizzled4 Recognition The Journal of Biological Chemistry. Feb, 2007 | Pubmed ID: 17158104 Order from Disorder: Self-organization in Mammalian Hair Patterning Proceedings of the National Academy of Sciences of the United States of America. Dec, 2006 | Pubmed ID: 17172440 Macular Degeneration: Recent Advances and Therapeutic Opportunities Nature Reviews. Neuroscience. Nov, 2006 | Pubmed ID: 17033682 Effects of L1 Retrotransposon Insertion on Transcript Processing, Localization and Accumulation: Lessons from the Retinal Degeneration 7 Mouse and Implications for the Genomic Ecology of L1 Elements Human Molecular Genetics. Jul, 2006 | Pubmed ID: 16723373 Ca2+-activated Cl- Current from Human Bestrophin-4 in Excised Membrane Patches The Journal of General Physiology. Jun, 2006 | Pubmed ID: 16702355 The Role of Frizzled3 and Frizzled6 in Neural Tube Closure and in the Planar Polarity of Inner-ear Sensory Hair Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2006 | Pubmed ID: 16495441 An Evolutionary Perspective on the Photoreceptor Damage Response American Journal of Ophthalmology. Mar, 2006 | Pubmed ID: 16490507 Axonal Growth and Guidance Defects in Frizzled3 Knock-out Mice: a Comparison of Diffusion Tensor Magnetic Resonance Imaging, Neurofilament Staining, and Genetically Directed Cell Labeling The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2006 | Pubmed ID: 16407530 Written in Our Genes? Science (New York, N.Y.). Jun, 2005 | Pubmed ID: 15961653 The Genomic Response to Retinal Disease and Injury: Evidence for Endothelin Signaling from Photoreceptors to Glia The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2005 | Pubmed ID: 15872101 The Rod Photoreceptor-specific Nuclear Receptor Nr2e3 Represses Transcription of Multiple Cone-specific Genes The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2005 | Pubmed ID: 15634773 Quantitative Analysis of Neuronal Morphologies in the Mouse Retina Visualized by Using a Genetically Directed Reporter The Journal of Comparative Neurology. Dec, 2004 | Pubmed ID: 15558785 Proteolytic Shedding of the Extracellular Domain of Photoreceptor Cadherin. Implications for Outer Segment Assembly The Journal of Biological Chemistry. Oct, 2004 | Pubmed ID: 15284225 Frizzled6 Controls Hair Patterning in Mice Proceedings of the National Academy of Sciences of the United States of America. Jun, 2004 | Pubmed ID: 15169958 Vascular Development in the Retina and Inner Ear: Control by Norrin and Frizzled-4, a High-affinity Ligand-receptor Pair Cell. Mar, 2004 | Pubmed ID: 15035989 An Outer Segment Localization Signal at the C Terminus of the Photoreceptor-specific Retinol Dehydrogenase The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2004 | Pubmed ID: 15028754 Proximal and Distal Sequences Control UV Cone Pigment Gene Expression in Transgenic Zebrafish The Journal of Biological Chemistry. Apr, 2004 | Pubmed ID: 14966125 Anterior-posterior Guidance of Commissural Axons by Wnt-frizzled Signaling Science (New York, N.Y.). Dec, 2003 | Pubmed ID: 14671310 A Strabismus Susceptibility Locus on Chromosome 7p Proceedings of the National Academy of Sciences of the United States of America. Oct, 2003 | Pubmed ID: 14519848 Genetically Engineered Mice with an Additional Class of Cone Photoreceptors: Implications for the Evolution of Color Vision Proceedings of the National Academy of Sciences of the United States of America. Sep, 2003 | Pubmed ID: 14500905 Structure-function Analysis of the Bestrophin Family of Anion Channels The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12907679 A Noninvasive Genetic/pharmacologic Strategy for Visualizing Cell Morphology and Clonal Relationships in the Mouse The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2003 | Pubmed ID: 12657690 Frizzled-3 is Required for the Development of Major Fiber Tracts in the Rostral CNS The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2002 | Pubmed ID: 12351730 The Vitelliform Macular Dystrophy Protein Defines a New Family of Chloride Channels Proceedings of the National Academy of Sciences of the United States of America. Mar, 2002 | Pubmed ID: 11904445 Role of a Locus Control Region in the Mutually Exclusive Expression of Human Red and Green Cone Pigment Genes Proceedings of the National Academy of Sciences of the United States of America. Jan, 2002 | Pubmed ID: 11773636 Fare Cilt ve Saç Folikül Desenlendirme ve Duyusal Akson Morfoloji Analizi Uygulanması Düz Görüntüleme Dağı Hao Chang1, Yanshu Wang1, Hao Wu1, Jeremy Nathans1,2,3 1Department of Molecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, 2Department of Neuroscience, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, 3Department of Ophthalmology, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine JoVE 51749 Neuroscience
Fare Cilt ve Saç Folikül Desenlendirme ve Duyusal Akson Morfoloji Analizi Uygulanması Düz Görüntüleme Dağı Hao Chang1, Yanshu Wang1, Hao Wu1, Jeremy Nathans1,2,3 1Department of Molecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, 2Department of Neuroscience, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, 3Department of Ophthalmology, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine JoVE 51749 Neuroscience
