Jianglin Fan Department of Molecular Pathology University of Yamanashi School of Medicine Biography Publications Institution JoVE Articles Jianglin Fan Jianglin Fan is Professor and Chairman of Molecular Pathology at University of Yamanashi School of Medicine, Yamanashi, Japan. He received his MD degree at Yanbian University School of Medicine, China and Ph.D. degree at Saga University, Japan. He got his postdoctoral training at Gladstone Institute, University of California, San Francisco. Dr. Fan has been working on atherosclerosis for more than 30 years and his research interests include elucidation of the molecular mechanisms of atherosclerosis, lipid and lipoprotein metabolism, and inflammation. One of his major achievements was to develop novel transgenic and knockout rabbit models for the study of cardiovascular disease. His work has led to more than 180 publications in prestigious peer-review journals. Publications Human Apolipoprotein A-II Reduces Atherosclerosis in Knock-in Rabbits Atherosclerosis. 01, 2021 | Pubmed ID: 33296791 "Coral Reef"-Like Calcifications: Communities of Uncomplicated Calcified Nodules Journal of Atherosclerosis and Thrombosis. Sep, 2020 | Pubmed ID: 32779624 Apolipoprotein CIII Deficiency Protects Against Atherosclerosis in Knockout Rabbits Arteriosclerosis, Thrombosis, and Vascular Biology. 09, 2020 | Pubmed ID: 32757647 Endothelial Lipase Exerts Its Anti-Atherogenic Effect Through Increased Catabolism of β-VLDLs Journal of Atherosclerosis and Thrombosis. May, 2020 | Pubmed ID: 32448826 Genetic and Molecular Features for Hepadnavirus and Plague Infections in the Himalayan Marmot Genome. Jun, 2020 | Pubmed ID: 32308030 IMarmot: an Integrative Platform for Comparative and Functional Genomics of Marmots BMC Genomics. Mar, 2020 | Pubmed ID: 32228437 Macrophage-derived MMP-9 Enhances the Progression of Atherosclerotic Lesions and Vascular Calcification in Transgenic Rabbits Journal of Cellular and Molecular Medicine. 04, 2020 | Pubmed ID: 32126159 Sex Hormones Affect Endothelial Lipase-mediated Lipid Metabolism and Atherosclerosis Lipids in Health and Disease. Dec, 2019 | Pubmed ID: 31870448 Connexin43 Contributes to Inflammasome Activation and Lipopolysaccharide-Initiated Acute Renal Injury Modulation of Intracellular Oxidative Status Antioxidants & Redox Signaling. 12, 2019 | Pubmed ID: 31319679 Cepharanthine Hydrochloride Degrades Polyglutamine-expanded Androgen Receptor Proteins Through an Autophagy Pathway in Neuron Cells European Journal of Pharmacology. Oct, 2019 | Pubmed ID: 31310754 Bisphenol-A Induces Neurodegeneration Through Disturbance of Intracellular Calcium Homeostasis in Human Embryonic Stem Cells-derived Cortical Neurons Chemosphere. Aug, 2019 | Pubmed ID: 31102917 Several Circulating MiRNAs Related to Hyperlipidemia and Atherosclerotic Cardiovascular Diseases Lipids in Health and Disease. Apr, 2019 | Pubmed ID: 31010436 Renovascular Hypertension Aggravates Atherosclerosis in Cholesterol-Fed Rabbits Journal of Vascular Research. Month, 2019 | Pubmed ID: 30947215 Generation of Hyperlipidemic Rabbit Models Using Multiple SgRNAs Targeted CRISPR/Cas9 Gene Editing System Lipids in Health and Disease. Mar, 2019 | Pubmed ID: 30885208 Hypoxic and Cold Adaptation Insights from the Himalayan Marmot Genome IScience. Jan, 2019 | Pubmed ID: 30581096 Extracellular Vesicles Derived from Donor Oviduct Fluid Improved Birth Rates After Embryo Transfer in Mice Reproduction, Fertility, and Development. Jan, 2019 | Pubmed ID: 30196804 Detection of Potential New Biomarkers of Atherosclerosis by Probe Electrospray Ionization Mass Spectrometry Metabolomics : Official Journal of the Metabolomic Society. 02, 2018 | Pubmed ID: 30830369 Genomic and Transcriptomic Analysis of Hypercholesterolemic Rabbits: Progress and Perspectives International Journal of Molecular Sciences. Nov, 2018 | Pubmed ID: 30413026 Salusin-α Inhibits Proliferation and Migration of Vascular Smooth Muscle Cell Via Akt/mTOR Signaling Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. Month, 2018 | Pubmed ID: 30384378 Hypertension Enhances Advanced Atherosclerosis and Induces Cardiac Death in Watanabe Heritable Hyperlipidemic Rabbits The American Journal of Pathology. 12, 2018 | Pubmed ID: 30248339 Spontaneous Severe Hypercholesterolemia and Atherosclerosis Lesions in Rabbits with Deficiency of Low-density Lipoprotein Receptor (LDLR) on Exon 7 EBioMedicine. Oct, 2018 | Pubmed ID: 30243490 Treatment of Atherosclerosis by Traditional Chinese Medicine: Questions and Quandaries Atherosclerosis. 10, 2018 | Pubmed ID: 30212682 Western Diet Feeding Influences Gut Microbiota Profiles in ApoE Knockout Mice Lipids in Health and Disease. Jul, 2018 | Pubmed ID: 30021609 Establishment of a Novel Non‑alcoholic Fatty Liver Disease Model Using Cholesterol‑fed Rabbits with Reference to the Potential Role of Endoplasmic Reticulum Stress Molecular Medicine Reports. Sep, 2018 | Pubmed ID: 30015906 Corrigendum to "Overexpression of Cholesteryl Ester Transfer Protein Increases Macrophage-Derived Foam Cell Accumulation in Atherosclerotic Lesions of Transgenic Rabbits" Mediators of Inflammation. Month, 2018 | Pubmed ID: 29849198 Differential Patterns of Secreted Frizzled-Related Protein 4 (SFRP4) in Adipocyte Differentiation: Adipose Depot Specificity Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. Month, 2018 | Pubmed ID: 29730658 Transcriptomic Analysis of the Liver of Cholesterol-fed Rabbits Reveals Altered Hepatic Lipid Metabolism and Inflammatory Response Scientific Reports. 04, 2018 | Pubmed ID: 29692426 Sphingolipid De Novo Biosynthesis is Essential for Intestine Cell Survival and Barrier Function Cell Death & Disease. 02, 2018 | Pubmed ID: 29415989 Principles and Applications of Rabbit Models for Atherosclerosis Research Journal of Atherosclerosis and Thrombosis. Mar, 2018 | Pubmed ID: 29046488 Overexpression of Cholesteryl Ester Transfer Protein Increases Macrophage-Derived Foam Cell Accumulation in Atherosclerotic Lesions of Transgenic Rabbits Mediators of Inflammation. Month, 2017 | Pubmed ID: 29317793 Comparative Studies of Three Cholesteryl Ester Transfer Proteins and Their Interactions with Known Inhibitors PloS One. Month, 2017 | Pubmed ID: 28767652 Mediator 1 Is Atherosclerosis Protective by Regulating Macrophage Polarization Arteriosclerosis, Thrombosis, and Vascular Biology. 08, 2017 | Pubmed ID: 28642237 Increased Hepatic Expression of Endothelial Lipase Inhibits Cholesterol Diet-Induced Hypercholesterolemia and Atherosclerosis in Transgenic Rabbits Arteriosclerosis, Thrombosis, and Vascular Biology. 07, 2017 | Pubmed ID: 28546217 Bre Enhances Osteoblastic Differentiation by Promoting the Mdm2-Mediated Degradation of P53 Stem Cells (Dayton, Ohio). 07, 2017 | Pubmed ID: 28436570 Deficiency of Cholesteryl Ester Transfer Protein Protects Against Atherosclerosis in Rabbits Arteriosclerosis, Thrombosis, and Vascular Biology. 06, 2017 | Pubmed ID: 28428219 Glutathione Inhibits Antibody and Complement-mediated Immunologic Cell Injury Via Multiple Mechanisms Redox Biology. 08, 2017 | Pubmed ID: 28390315 Carbenoxolone Inhibits TRPV4 Channel-initiated Oxidative Urothelial Injury and Ameliorates Cyclophosphamide-induced Bladder Dysfunction Journal of Cellular and Molecular Medicine. Feb, 2017 | Pubmed ID: 28244642 Protein Inhibitor of Activated STAT3 Suppresses Oxidized LDL-induced Cell Responses During Atherosclerosis in Apolipoprotein E-deficient Mice Scientific Reports. 11, 2016 | Pubmed ID: 27845432 Combined B, T and NK Cell Deficiency Accelerates Atherosclerosis in BALB/c Mice PloS One. Month, 2016 | Pubmed ID: 27564380 Hydrogen Sulfide Inhibits Development of Atherosclerosis Through Up-regulating Protein S-nitrosylation Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Oct, 2016 | Pubmed ID: 27427853 Hyperlipidemia-associated Gene Variations and Expression Patterns Revealed by Whole-genome and Transcriptome Sequencing of Rabbit Models Scientific Reports. 06, 2016 | Pubmed ID: 27245873 Plasma High-Mannose and Complex/Hybrid N-Glycans Are Associated with Hypercholesterolemia in Humans and Rabbits PloS One. Month, 2016 | Pubmed ID: 26999365 Angiotensin II Destabilizes Coronary Plaques in Watanabe Heritable Hyperlipidemic Rabbits Arteriosclerosis, Thrombosis, and Vascular Biology. 05, 2016 | Pubmed ID: 26988589 Dietary Cocoa Powder Improves Hyperlipidemia and Reduces Atherosclerosis in ApoE Deficient Mice Through the Inhibition of Hepatic Endoplasmic Reticulum Stress Mediators of Inflammation. Month, 2016 | Pubmed ID: 26980943 AMPK Suppresses Connexin43 Expression in the Bladder and Ameliorates Voiding Dysfunction in Cyclophosphamide-induced Mouse Cystitis Scientific Reports. Jan, 2016 | Pubmed ID: 26806558 ApoE Knockout Rabbits: A Novel Model for the Study of Human Hyperlipidemia Atherosclerosis. Feb, 2016 | Pubmed ID: 26724529 Production of Human Apolipoprotein(a) Transgenic NIBS Miniature Pigs by Somatic Cell Nuclear Transfer Experimental Animals. Month, 2016 | Pubmed ID: 26411321 Autocrine Human Urotensin II Enhances Macrophage-Derived Foam Cell Formation in Transgenic Rabbits BioMed Research International. Month, 2015 | Pubmed ID: 26640798 High-fructose and High-fat Diet-induced Insulin Resistance Enhances Atherosclerosis in Watanabe Heritable Hyperlipidemic Rabbits Nutrition & Metabolism. Month, 2015 | Pubmed ID: 26265929 Practical Assessment of the Quantification of Atherosclerotic Lesions in ApoE⁻/⁻ Mice Molecular Medicine Reports. Oct, 2015 | Pubmed ID: 26239265 Combined Use of Probucol and Cilostazol with Atorvastatin Attenuates Atherosclerosis in Moderately Hypercholesterolemic Rabbits Lipids in Health and Disease. Jul, 2015 | Pubmed ID: 26220196 Motility and Fertility of Rabbit Sperm Cryopreserved Using Soybean Lecithin As an Alternative to Egg Yolk Theriogenology. Oct, 2015 | Pubmed ID: 26208436 Production of Cloned Miniature Pigs Expressing High Levels of Human Apolipoprotein(a) in Plasma PloS One. Month, 2015 | Pubmed ID: 26147378 Carbonate Ion-enriched Hot Spring Water Promotes Skin Wound Healing in Nude Rats PloS One. Month, 2015 | Pubmed ID: 25671581 Bisphenol A Exposure Induces Metabolic Disorders and Enhances Atherosclerosis in Hyperlipidemic Rabbits Journal of Applied Toxicology : JAT. Sep, 2015 | Pubmed ID: 25619500 Rabbit Models for the Study of Human Atherosclerosis: from Pathophysiological Mechanisms to Translational Medicine Pharmacology & Therapeutics. Feb, 2015 | Pubmed ID: 25277507 Bisphenol A Exposure Enhances Atherosclerosis in WHHL Rabbits PloS One. Month, 2014 | Pubmed ID: 25333893 Homocysteine Reduces Protein S-nitrosylation in Endothelium International Journal of Molecular Medicine. Nov, 2014 | Pubmed ID: 25189662 Demonstration of an Add-on Effect of Probucol and Cilostazol on the Statin-induced Anti-atherogenic Effects Histology and Histopathology. Dec, 2014 | Pubmed ID: 25078428 C-reactive Protein and Arteriosclerosis Mediators of Inflammation. Month, 2014 | Pubmed ID: 24976688 Effects of Antisense Oligonucleotides Against C-reactive Protein on the Development of Atherosclerosis in WHHL Rabbits Mediators of Inflammation. Month, 2014 | Pubmed ID: 24872601 Animal Models of C-reactive Protein Mediators of Inflammation. Month, 2014 | Pubmed ID: 24872599 Effects of Type III Antifreeze Protein on Sperm and Embryo Cryopreservation in Rabbit Cryobiology. Aug, 2014 | Pubmed ID: 24809634 Silencing Herpes Simplex Virus Type 1 Capsid Protein Encoding Genes by SiRNA: a Promising Antiviral Therapeutic Approach PloS One. Month, 2014 | Pubmed ID: 24794394 Effects of Cholesterol-loaded Cyclodextrins on the Rate and the Quality of Motility in Frozen and Thawed Rabbit Sperm Experimental Animals. Month, 2014 | Pubmed ID: 24770640 Urotensin II Promotes Atherosclerosis in Cholesterol-fed Rabbits PloS One. Month, 2014 | Pubmed ID: 24747943 Probucol Suppresses Macrophage Infiltration and MMP Expression in Atherosclerotic Plaques of WHHL Rabbits Journal of Atherosclerosis and Thrombosis. Month, 2014 | Pubmed ID: 24584175 Epidermal Growth Factor Receptor-PI3K Signaling Controls Cofilin Activity to Facilitate Herpes Simplex Virus 1 Entry into Neuronal Cells MBio. Jan, 2014 | Pubmed ID: 24425731 Ubiquitin-proteasome-dependent Slingshot 1 Downregulation in Neuronal Cells Inactivates Cofilin to Facilitate HSV-1 Replication Virology. Jan, 2014 | Pubmed ID: 24418541 Effective Gene Targeting in Rabbits Using RNA-guided Cas9 Nucleases Journal of Molecular Cell Biology. Feb, 2014 | Pubmed ID: 24403564 Probucol Inhibits the Initiation of Atherosclerosis in Cholesterol-fed Rabbits Lipids in Health and Disease. Nov, 2013 | Pubmed ID: 24188322 Probucol and Cilostazol Exert a Combinatorial Anti-atherogenic Effect in Cholesterol-fed Rabbits Thrombosis Research. Nov, 2013 | Pubmed ID: 24090606 Comparative Analyses of Lipoprotein Lipase, Hepatic Lipase, and Endothelial Lipase, and Their Binding Properties with Known Inhibitors PloS One. Month, 2013 | Pubmed ID: 23991054 Expression Systems and Species Used for Transgenic Animal Bioreactors BioMed Research International. Month, 2013 | Pubmed ID: 23586046 Human Apolipoprotein A-II Protects Against Diet-induced Atherosclerosis in Transgenic Rabbits Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2013 | Pubmed ID: 23241412 Characteristics of Himalayan Marmots and Their Response to an Atherogenic Diet Experimental Animals / Japanese Association for Laboratory Animal Science. Month, 2012 | Pubmed ID: 22850646 Protective Effects of 20(s)-protopanaxtriol on Viral Myocarditis Infected by Coxsackievirus B3 Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. Month, 2012 | Pubmed ID: 22688124 Apigenin Inhibits the Expression of IL-6, IL-8, and ICAM-1 in DEHP-stimulated Human Umbilical Vein Endothelial Cells and in Vivo Inflammation. Aug, 2012 | Pubmed ID: 22527144 Temporal and Quantitative Analysis of Atherosclerotic Lesions in Diet-induced Hypercholesterolemic Rabbits Journal of Biomedicine & Biotechnology. Month, 2012 | Pubmed ID: 22505812 High-dose Rosiglitazone is Pro-atherogenic in Cholesterol-fed Rabbits Atherosclerosis. May, 2012 | Pubmed ID: 22377393 Expression of TRPV1 in Rabbits and Consuming Hot Pepper Affects Its Body Weight Molecular Biology Reports. Jul, 2012 | Pubmed ID: 22327653 Endothelial Lipase Mediates HDL Levels in Normal and Hyperlipidemic Rabbits Journal of Atherosclerosis and Thrombosis. Month, 2012 | Pubmed ID: 22240910 C-reactive Protein is Associated with the Progression of Acute Embolic Stroke in Rabbit Model Journal of Thrombosis and Thrombolysis. May, 2012 | Pubmed ID: 21874402 Perfluorooctane Sulfonate Impairs the Cardiac Development of a Marine Medaka (Oryzias Melastigma) Aquatic Toxicology (Amsterdam, Netherlands). Sep, 2011 | Pubmed ID: 21684243 Effects of Human C-reactive Protein on Pathogenesis of Features of the Metabolic Syndrome Hypertension. Apr, 2011 | Pubmed ID: 21357282 Hypertriglyceridemia and Delayed Clearance of Fat Load in Transgenic Rabbits Expressing Human Apolipoprotein CIII Transgenic Research. Aug, 2011 | Pubmed ID: 21120692 High-fat Diet Without Excess Calories Induces Metabolic Disorders and Enhances Atherosclerosis in Rabbits Atherosclerosis. Nov, 2010 | Pubmed ID: 20832799 Expression of CXCR4 and Its Ligand SDF-1 in Intestinal-type Gastric Cancer is Associated with Lymph Node and Liver Metastasis Anticancer Research. Nov, 2009 | Pubmed ID: 20032431 Human C-reactive Protein Does Not Promote Atherosclerosis in Transgenic Rabbits Circulation. Nov, 2009 | Pubmed ID: 19901190 Expression of Human ApoAII in Transgenic Rabbits Leads to Dyslipidemia: a New Model for Combined Hyperlipidemia Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2009 | Pubmed ID: 19778946 Endotoxin Accelerates Atherosclerosis Independent of Complement Activation Thrombosis Research. Feb, 2009 | Pubmed ID: 18692867 Unstable Coronary Plaques and Cardiac Events in Myocardial Infarction-prone Watanabe Heritable Hyperlipidemic Rabbits: Questions and Quandaries Current Opinion in Lipidology. Dec, 2008 | Pubmed ID: 18957890 Temporal and Quantitative Analysis of Expression of Metalloproteinases (MMPs) and Their Endogenous Inhibitors in Atherosclerotic Lesions Histology and Histopathology. Dec, 2008 | Pubmed ID: 18830936 The Effects of Rosiglitazone on Aortic Atherosclerosis of Cholesterol-fed Rabbits Thrombosis Research. Month, 2008 | Pubmed ID: 18561986 Matrix Metalloproteinase 12 Accelerates the Initiation of Atherosclerosis and Stimulates the Progression of Fatty Streaks to Fibrous Plaques in Transgenic Rabbits The American Journal of Pathology. May, 2008 | Pubmed ID: 18403602 Spontaneous Atherosclerosis in Aged Lipoprotein Lipase-deficient Mice with Severe Hypertriglyceridemia on a Normal Chow Diet Circulation Research. Feb, 2008 | Pubmed ID: 18032735 Increased Expression of Human Macrophage Metalloelastase (MMP-12) is Associated with the Invasion of Endometrial Adenocarcinoma Pathology, Research and Practice. Month, 2007 | Pubmed ID: 17574772 Increased Expression of Vascular Endothelial Growth Factor in Kidney Leads to Progressive Impairment of Glomerular Functions Journal of the American Society of Nephrology : JASN. Jul, 2007 | Pubmed ID: 17554151 Re-establishment of Complement C6-deficient Rabbit Colony by Cryopreserved Sperm Transported from Abroad Experimental Animals / Japanese Association for Laboratory Animal Science. Apr, 2007 | Pubmed ID: 17460363 Lp(a) Enhances Coronary Atherosclerosis in Transgenic Watanabe Heritable Hyperlipidemic Rabbits Atherosclerosis. Aug, 2007 | Pubmed ID: 17045271 Expression of LPL in Endothelial-intact Artery Results in Lipid Deposition and Vascular Cell Adhesion Molecule-1 Upregulation in Both LPL and ApoE-deficient Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2007 | Pubmed ID: 17038632 Macrophage Metalloelastase Accelerates the Progression of Atherosclerosis in Transgenic Rabbits Circulation. Apr, 2006 | Pubmed ID: 16636188 Localized Vessel Expression of Lipoprotein Lipase in Rabbits Leads to Rapid Lipid Deposition in the Balloon-injured Arterial Wall Atherosclerosis. Jul, 2006 | Pubmed ID: 16191430 Transgenic Rabbits with Increased VEGF Expression Develop Hemangiomas in the Liver: a New Model for Kasabach-Merritt Syndrome Laboratory Investigation; a Journal of Technical Methods and Pathology. Dec, 2005 | Pubmed ID: 16200077 C-reactive Protein in Atherosclerotic Lesions: Its Origin and Pathophysiological Significance The American Journal of Pathology. Oct, 2005 | Pubmed ID: 16192648 Establishment of a SPF Colony of Human Apo(a) Transgenic Rabbits by Frozen-thawed Embryo Transfer Experimental Animals / Japanese Association for Laboratory Animal Science. Jul, 2005 | Pubmed ID: 16093649 Macrophage-derived Lipoprotein Lipase Increases Aortic Atherosclerosis in Cholesterol-fed Tg Rabbits Atherosclerosis. Mar, 2005 | Pubmed ID: 15721013 Enhanced Aortic Atherosclerosis in Transgenic Watanabe Heritable Hyperlipidemic Rabbits Expressing Lipoprotein Lipase Cardiovascular Research. Feb, 2005 | Pubmed ID: 15639492 High Lipoprotein Lipase Activity Increases Insulin Sensitivity in Transgenic Rabbits Metabolism: Clinical and Experimental. Jan, 2005 | Pubmed ID: 15562391 Association of Increased Expression of Macrophage Elastase (matrix Metalloproteinase 12) with Rheumatoid Arthritis Arthritis and Rheumatism. Oct, 2004 | Pubmed ID: 15476203 Overexpression of Human Matrix Metalloproteinase-12 Enhances the Development of Inflammatory Arthritis in Transgenic Rabbits The American Journal of Pathology. Oct, 2004 | Pubmed ID: 15466401 Macrophage-specific Overexpression of Human Matrix Metalloproteinase-12 in Transgenic Rabbits Transgenic Research. Jun, 2004 | Pubmed ID: 15359603 Correlation of Vulnerable Coronary Plaques to Sudden Cardiac Events. Lessons from a Myocardial Infarction-prone Animal Model (the WHHLMI Rabbit) Journal of Atherosclerosis and Thrombosis. Month, 2004 | Pubmed ID: 15356377 A Minipig Model of High-fat/high-sucrose Diet-induced Diabetes and Atherosclerosis International Journal of Experimental Pathology. Oct, 2004 | Pubmed ID: 15312127 Overexpression of Lipoprotein Lipase in Transgenic Rabbits Leads to Increased Small Dense LDL in Plasma and Promotes Atherosclerosis Laboratory Investigation; a Journal of Technical Methods and Pathology. Jun, 2004 | Pubmed ID: 15122303 NO-1886 Inhibits Size of Adipocytes, Suppresses Plasma Levels of Tumor Necrosis Factor-alpha and Free Fatty Acids, Improves Glucose Metabolism in High-fat/high-sucrose-fed Miniature Pigs Pharmacological Research : the Official Journal of the Italian Pharmacological Society. Mar, 2004 | Pubmed ID: 14726214 Overexpression of Lipoprotein Lipase in Transgenic Watanabe Heritable Hyperlipidemic Rabbits Improves Hyperlipidemia and Obesity The Journal of Biological Chemistry. Feb, 2004 | Pubmed ID: 14660566 Transgenic Rabbits As Therapeutic Protein Bioreactors and Human Disease Models Pharmacology & Therapeutics. Sep, 2003 | Pubmed ID: 12951161 Inflammatory Reactions in the Pathogenesis of Atherosclerosis Journal of Atherosclerosis and Thrombosis. Month, 2003 | Pubmed ID: 12740479 Development of an Animal Model for Spontaneous Myocardial Infarction (WHHLMI Rabbit) Arteriosclerosis, Thrombosis, and Vascular Biology. Jul, 2003 | Pubmed ID: 12738683 Matrix Metalloproteinase-12 Gene Expression in Human Vascular Smooth Muscle Cells Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Mar, 2003 | Pubmed ID: 12622720 Accelerated Atherosclerosis with Apolipoprotein(a) and Oxidized Low-density Lipoprotein Deposition in Acute Rejection of Transplanted Kidney: Analogous to Atherosclerosis Clinical Transplantation. Month, 2002 | Pubmed ID: 12464130 Increased Expression of Lipoprotein Lipase in Transgenic Rabbits Does Not Lead to Abnormalities in Skeletal and Heart Muscles Muscle & Nerve. Dec, 2002 | Pubmed ID: 12451608 A Rapid PCR Method of Genotyping LDL Receptor Mutations in WHHL Rabbits Journal of Atherosclerosis and Thrombosis. Month, 2002 | Pubmed ID: 12226556 Lipoprotein(a) Enhances Advanced Atherosclerosis and Vascular Calcification in WHHL Transgenic Rabbits Expressing Human Apolipoprotein(a) The Journal of Biological Chemistry. Dec, 2002 | Pubmed ID: 12196525 Lipoprotein(a) Promotes Smooth Muscle Cell Proliferation and Dedifferentiation in Atherosclerotic Lesions of Human Apo(a) Transgenic Rabbits The American Journal of Pathology. Jan, 2002 | Pubmed ID: 11786416 Isolement et analyse des lipoprotéines plasmatiques par ultracentrifugation Manabu Niimi1, Haizhao Yan1, Yajie Chen1, Yao Wang2, Jianglin Fan1,2 1Department of Molecular Pathology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 2School of Biotechnology and Health Sciences, Wuyi University JoVE 61790 Biochemistry La production de lapins de Knockout apolipoprotéine C-III à l'aide de zinc nucléases doigt Dongshan Yang1, Jifeng Zhang1, Jie Xu1, Tianqing Zhu1, Yanbo Fan1, Jianglin Fan2, Y. Eugene Chen1 1Center for Advanced Models for Translational Sciences and Therapeutics, Department of Internal Medicine, University of Michigan Medical Center, 2Department of Molecular Pathology, University of Yamanashi JoVE 50957 Medicine
Isolement et analyse des lipoprotéines plasmatiques par ultracentrifugation Manabu Niimi1, Haizhao Yan1, Yajie Chen1, Yao Wang2, Jianglin Fan1,2 1Department of Molecular Pathology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 2School of Biotechnology and Health Sciences, Wuyi University JoVE 61790 Biochemistry
La production de lapins de Knockout apolipoprotéine C-III à l'aide de zinc nucléases doigt Dongshan Yang1, Jifeng Zhang1, Jie Xu1, Tianqing Zhu1, Yanbo Fan1, Jianglin Fan2, Y. Eugene Chen1 1Center for Advanced Models for Translational Sciences and Therapeutics, Department of Internal Medicine, University of Michigan Medical Center, 2Department of Molecular Pathology, University of Yamanashi JoVE 50957 Medicine
