Joanna Poulton Nuffield Department of Obstetrics and Gynaecology University of Oxford Biography Publications Institution JoVE Articles Joanna Poulton has not added a biography. If you are Joanna Poulton and would like to personalize this page please email our Author Liaison for assistance. Publications Use of FGF-21 As a Biomarker of Mitochondrial Disease in Clinical Practice Journal of Clinical Medicine. Aug, 2017 | Pubmed ID: 28825656 Erratum To: Genetic Counselling for Maternally Inherited Mitochondrial Disorders Molecular Diagnosis & Therapy. Aug, 2017 | Pubmed ID: 28676952 Modulating Mitophagy in Mitochondrial Disease Current Medicinal Chemistry. Jun, 2017 | Pubmed ID: 28618992 Genetic Counselling for Maternally Inherited Mitochondrial Disorders Molecular Diagnosis & Therapy. Aug, 2017 | Pubmed ID: 28536827 Clinicopathologic and Molecular Spectrum of RNASEH1-related Mitochondrial Disease Neurology. Genetics. Jun, 2017 | Pubmed ID: 28508084 Childhood-onset Leber Hereditary Optic Neuropathy The British Journal of Ophthalmology. Nov, 2017 | Pubmed ID: 28314831 Dysregulated Mitophagy and Mitochondrial Organization in Optic Atrophy Due to OPA1 Mutations Neurology. Jan, 2017 | Pubmed ID: 27974645 Clinical Features of the Pathogenic M.5540G>A Mitochondrial Transfer RNA Tryptophan Gene Mutation Neuromuscular Disorders : NMD. Oct, 2016 | Pubmed ID: 27618137 Pathogenic MtDNA Mutations Causing Mitochondrial Myopathy: The Need for Muscle Biopsy Neurology. Genetics. Aug, 2016 | Pubmed ID: 27536729 Modulating Mitochondrial Quality in Disease Transmission: Towards Enabling Mitochondrial DNA Disease Carriers to Have Healthy Children Biochemical Society Transactions. Aug, 2016 | Pubmed ID: 27528757 Incidence of Primary Mitochondrial Disease in Children Younger Than 2 Years Presenting With Acute Liver Failure Journal of Pediatric Gastroenterology and Nutrition. Dec, 2016 | Pubmed ID: 27482763 Mitophagy Plays a Central Role in Mitochondrial Ageing Mammalian Genome : Official Journal of the International Mammalian Genome Society. Aug, 2016 | Pubmed ID: 27352213 The M.13051G>A Mitochondrial DNA Mutation Results in Variable Neurology and Activated Mitophagy Neurology. May, 2016 | Pubmed ID: 27164671 Mitochondrial Content is Central to Nuclear Gene Expression: Profound Implications for Human Health BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Feb, 2016 | Pubmed ID: 26725055 Resistance of Dynamin-related Protein 1 Oligomers to Disassembly Impairs Mitophagy, Resulting in Myocardial Inflammation and Heart Failure The Journal of Biological Chemistry. Oct, 2015 | Pubmed ID: 26370078 A Novel Quantitative Assay of Mitophagy: Combining High Content Fluorescence Microscopy and Mitochondrial DNA Load to Quantify Mitophagy and Identify Novel Pharmacological Tools Against Pathogenic Heteroplasmic MtDNA Pharmacological Research. Oct, 2015 | Pubmed ID: 26196248 Metabolic Rescue in Pluripotent Cells from Patients with MtDNA Disease Nature. Aug, 2015 | Pubmed ID: 26176921 Is Placental Mitochondrial Function a Regulator That Matches Fetal and Placental Growth to Maternal Nutrient Intake in the Mouse? PloS One. 2015 | Pubmed ID: 26132581 Sodium Valproate Induces Mitochondrial Respiration Dysfunction in HepG2 in Vitro Cell Model Toxicology. May, 2015 | Pubmed ID: 25745980 Mitochondrial DNA Disease and Developmental Implications for Reproductive Strategies Molecular Human Reproduction. Jan, 2015 | Pubmed ID: 25425607 MtDNA Segregation in Heteroplasmic Tissues is Common in Vivo and Modulated by Haplotype Differences and Developmental Stage Cell Reports. Jun, 2014 | Pubmed ID: 24910436 Mitochondrial Encephalomyopathy with Lactic Acidosis and Stroke-like Episodes (MELAS) in the Older Adult Practical Neurology. Dec, 2014 | Pubmed ID: 24828681 A National Perspective on Prenatal Testing for Mitochondrial Disease European Journal of Human Genetics : EJHG. Nov, 2014 | Pubmed ID: 24642831 Clinical, Biochemical, Cellular and Molecular Characterization of Mitochondrial DNA Depletion Syndrome Due to Novel Mutations in the MPV17 Gene European Journal of Human Genetics : EJHG. Feb, 2014 | Pubmed ID: 23714749 Unexplained Gastrointestinal Symptoms: Think Mitochondrial Disease Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. Jun, 2013 | Pubmed ID: 23768727 The Association of the Mitochondrial DNA OriB Variant (16184-16193 Polycytosine Tract) with Type 2 Diabetes in Europid Populations Diabetologia. Sep, 2013 | Pubmed ID: 23702607 Prospective Study of POLG Mutations Presenting in Children with Intractable Epilepsy: Prevalence and Clinical Features Epilepsia. Jun, 2013 | Pubmed ID: 23448099 Adults with RRM2B-related Mitochondrial Disease Have Distinct Clinical and Molecular Characteristics Brain : a Journal of Neurology. Nov, 2012 | Pubmed ID: 23107649 Therapeutic Treatments of MtDNA Diseases at the Earliest Stages of Human Development Mitochondrion. Sep, 2011 | Pubmed ID: 21147275 Transmission of Mitochondrial DNA Diseases and Ways to Prevent Them PLoS Genetics. Aug, 2010 | Pubmed ID: 20711358 174th ENMC International Workshop: Applying Pre-implantation Genetic Diagnosis to MtDNA Diseases: Implications of Scientific Advances 19-21 March 2010, Naarden, The Netherlands Neuromuscular Disorders : NMD. Aug, 2010 | Pubmed ID: 20627569 Collated Mutations in Mitochondrial DNA (mtDNA) Depletion Syndrome (excluding the Mitochondrial Gamma Polymerase, POLG1) Biochimica Et Biophysica Acta. Dec, 2009 | Pubmed ID: 19748572 Anticancer DNA Intercalators Cause P53-dependent Mitochondrial DNA Nucleoid Re-modelling Oncogene. Nov, 2009 | Pubmed ID: 19684617 163rd ENMC International Workshop: Nucleoid and Nucleotide Biology in Syndromes of Mitochondrial DNA Depletion Myopathy 12-14 December 2008, Naarden, The Netherlands Neuromuscular Disorders : NMD. Jun, 2009 | Pubmed ID: 19464176 The Mitochondrial DNA T16189C Polymorphism and HIV-associated Cardiomyopathy: a Genotype-phenotype Association Study BMC Medical Genetics. Apr, 2009 | Pubmed ID: 19397801 Preventing Transmission of Maternally Inherited Mitochondrial DNA Diseases BMJ (Clinical Research Ed.). Jan, 2009 | Pubmed ID: 19181733 Mitochondrial DNA is a Direct Target of Anti-cancer Anthracycline Drugs Biochemical and Biophysical Research Communications. Jan, 2009 | Pubmed ID: 19032935 Depletion of Mitochondrial DNA in Fibroblast Cultures from Patients with POLG1 Mutations is a Consequence of Catalytic Mutations Human Molecular Genetics. Aug, 2008 | Pubmed ID: 18487244 Liver MtDNA Content Increases During Development: a Comparison of Methods and the Importance of Age- and Tissue-specific Controls for the Diagnosis of MtDNA Depletion Mitochondrion. Dec, 2007 | Pubmed ID: 17981517 Detailed Analysis of Variation at and Around Mitochondrial Position 16189 in a Large Finnish Cohort Reveals No Significant Associations with Early Growth or Metabolic Phenotypes at Age 31 Years The Journal of Clinical Endocrinology and Metabolism. Aug, 2007 | Pubmed ID: 17535991 Detection of Mitochondrial DNA Depletion in Living Human Cells Using PicoGreen Staining Experimental Cell Research. Feb, 2005 | Pubmed ID: 15652355 Segregation of Mitochondrial DNA (mtDNA) in Human Oocytes and in Animal Models of MtDNA Disease: Clinical Implications Reproduction (Cambridge, England). Jun, 2002 | Pubmed ID: 12052229 Type 2 Diabetes is Associated with a Common Mitochondrial Variant: Evidence from a Population-based Case-control Study Human Molecular Genetics. Jun, 2002 | Pubmed ID: 12045211 생체 외에서 그리고 Vivo에서 인간 세포, C. 선 충, 쥐에서 Mitophagy의 검출 Evandro F. Fang1,6, Konstantinos Palikaras2, Nuo Sun3, Elayne M. Fivenson1, Ryan D. Spangler4, Jesse S. Kerr1, Stephanie A. Cordonnier1, Yujun Hou1, Eszter Dombi5, Henok Kassahun6, Nektarios Tavernarakis2,7, Joanna Poulton5, Hilde Nilsen6, Vilhelm A. Bohr1,8 1Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, 2Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas, 3Center for Molecular Medicine, National Heart Lung and Blood Institute, National Institutes of Health, 4Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, 5Nuffield Department of Obstetrics and Gynaecology, University of Oxford, 6Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, 7Department of Basic Sciences, Faculty of Medicine, University of Crete, 8Danish Center for Healthy Aging, University of Copenhagen JoVE 56301 Medicine
생체 외에서 그리고 Vivo에서 인간 세포, C. 선 충, 쥐에서 Mitophagy의 검출 Evandro F. Fang1,6, Konstantinos Palikaras2, Nuo Sun3, Elayne M. Fivenson1, Ryan D. Spangler4, Jesse S. Kerr1, Stephanie A. Cordonnier1, Yujun Hou1, Eszter Dombi5, Henok Kassahun6, Nektarios Tavernarakis2,7, Joanna Poulton5, Hilde Nilsen6, Vilhelm A. Bohr1,8 1Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, 2Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas, 3Center for Molecular Medicine, National Heart Lung and Blood Institute, National Institutes of Health, 4Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, 5Nuffield Department of Obstetrics and Gynaecology, University of Oxford, 6Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, 7Department of Basic Sciences, Faculty of Medicine, University of Crete, 8Danish Center for Healthy Aging, University of Copenhagen JoVE 56301 Medicine
