Johan Flygare

Publications

• Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia
  Molecular Therapy : the Journal of the American Society of Gene Therapy. 08, 2017   |   Pubmed ID: 28434866
• Direct Lineage Reprogramming: a Useful Addition to the Blood Cell Research Toolbox
  Expert Review of Hematology. 02, 2017   |   Pubmed ID: 27967256
• Direct Conversion of Fibroblasts to Megakaryocyte Progenitors
  Cell Reports. 10, 2016   |   Pubmed ID: 27732845
• Defining the Minimal Factors Required for Erythropoiesis Through Direct Lineage Conversion
  Cell Reports. 06, 2016   |   Pubmed ID: 27264182
• Glucocorticoids Improve Erythroid Progenitor Maintenance and Dampen Trp53 Response in a Mouse Model of Diamond-Blackfan Anaemia
  British Journal of Haematology. Nov, 2015   |   Pubmed ID: 26305041
• Gene Therapy Cures the Anemia and Lethal Bone Marrow Failure in a Mouse Model of RPS19-deficient Diamond-Blackfan Anemia
  Haematologica. Dec, 2014   |   Pubmed ID: 25216681
• Fetal Hepatic Progenitors Support Long-term Expansion of Hematopoietic Stem Cells
  Experimental Hematology. May, 2013   |   Pubmed ID: 23415675
• Dietary L-leucine Improves the Anemia in a Mouse Model for Diamond-Blackfan Anemia
  Blood. Sep, 2012   |   Pubmed ID: 22791294
• Progress Towards Mechanism-based Treatment for Diamond-Blackfan Anemia
  TheScientificWorldJournal. Month, 2012   |   Pubmed ID: 22619618
• From Stem Cell to Red Cell: Regulation of Erythropoiesis at Multiple Levels by Multiple Proteins, RNAs, and Chromatin Modifications
  Blood. Dec, 2011   |   Pubmed ID: 21998215
• Mice with Ribosomal Protein S19 Deficiency Develop Bone Marrow Failure and Symptoms Like Patients with Diamond-Blackfan Anemia
  Blood. Dec, 2011   |   Pubmed ID: 21989989
• Gene Therapy of Diamond Blackfan Anemia CD34(+) Cells Leads to Improved Erythroid Development and Engraftment Following Transplantation
  Experimental Hematology. Nov, 2008   |   Pubmed ID: 18715690
• Ribosomal Protein S19 Deficiency Leads to Reduced Proliferation and Increased Apoptosis but Does Not Affect Terminal Erythroid Differentiation in a Cell Line Model of Diamond-Blackfan Anemia
  Stem Cells (Dayton, Ohio). Feb, 2008   |   Pubmed ID: 17962699
• Endoglin is Not Critical for Hematopoietic Stem Cell Engraftment and Reconstitution but Regulates Adult Erythroid Development
  Stem Cells (Dayton, Ohio). Nov, 2007   |   Pubmed ID: 17673527
• Diamond-Blackfan Anemia: Erythropoiesis Lost in Translation
  Blood. Apr, 2007   |   Pubmed ID: 17164339
• Human RPS19, the Gene Mutated in Diamond-Blackfan Anemia, Encodes a Ribosomal Protein Required for the Maturation of 40S Ribosomal Subunits
  Blood. Feb, 2007   |   Pubmed ID: 16990592
• Development of Cellular Models for Ribosomal Protein S19 (RPS19)-deficient Diamond-blackfan Anemia Using Inducible Expression of SiRNA Against RPS19
  Molecular Therapy : the Journal of the American Society of Gene Therapy. Apr, 2005   |   Pubmed ID: 15771965
• Deficiency of Ribosomal Protein S19 in CD34+ Cells Generated by SiRNA Blocks Erythroid Development and Mimics Defects Seen in Diamond-Blackfan Anemia
  Blood. Jun, 2005   |   Pubmed ID: 15626736
• Lentiviral Vector Transduction of NOD/SCID Repopulating Cells Results in Multiple Vector Integrations Per Transduced Cell: Risk of Insertional Mutagenesis
  Blood. Feb, 2003   |   Pubmed ID: 12393514