John W. Eaton Department of Pharmacology and Toxicology University of Louisville Biography Publications Institution JoVE Articles John W. Eaton has not added a biography. If you are John W. Eaton and would like to personalize this page please email our Author Liaison for assistance. Publications Cancer Vaccines: Promising Therapeutics or an Unattainable Dream Vaccines. Jun, 2021 | Pubmed ID: 34207062 Heme Cytotoxicity is the Consequence of Endoplasmic Reticulum Stress in Atherosclerotic Plaque Progression Scientific Reports. 05, 2021 | Pubmed ID: 34001932 Dataset for Dose and Time-dependent Transcriptional Response to Ionizing Radiation Exposure Data in Brief. Dec, 2019 | Pubmed ID: 31692674 Exosomes from GM-CSF Expressing Embryonic Stem Cells Are an Effective Prophylactic Vaccine for Cancer Prevention Oncoimmunology. 2019 | Pubmed ID: 30723593 Vaccination with Induced Pluripotent Stem Cells Confers Protection Against Cancer Stem Cell Investigation. 2018 | Pubmed ID: 30148156 Transcriptional Profile of Immediate Response to Ionizing Radiation Exposure Genomics Data. Mar, 2016 | Pubmed ID: 26981369 Pharmacological Induction of Ferritin Prevents Osteoblastic Transformation of Smooth Muscle Cells Journal of Cellular and Molecular Medicine. Feb, 2016 | Pubmed ID: 26499096 Heme-induced Contractile Dysfunction in Human Cardiomyocytes Caused by Oxidant Damage to Thick Filament Proteins Free Radical Biology & Medicine. Dec, 2015 | Pubmed ID: 26409224 How Heme Oxygenase-1 Prevents Heme-Induced Cell Death PloS One. 2015 | Pubmed ID: 26270345 Human Polymorphonuclear Neutrophils Specifically Recognize and Kill Cancerous Cells Oncoimmunology. 2014 | Pubmed ID: 25610737 Cancer Vaccines: Looking to the Future Oncoimmunology. Mar, 2013 | Pubmed ID: 23802081 Natural History of the Bruise: Formation, Elimination, and Biological Effects of Oxidized Hemoglobin Oxidative Medicine and Cellular Longevity. 2013 | Pubmed ID: 23766858 Control of Tumor-associated Macrophage Alternative Activation by Macrophage Migration Inhibitory Factor Journal of Immunology (Baltimore, Md. : 1950). Mar, 2013 | Pubmed ID: 23390297 Haem Oxygenase-1 Overexpression Alters Intracellular Iron Distribution The Biochemical Journal. Jan, 2013 | Pubmed ID: 22989377 Multi-peptide Immunotherapeutic Vaccine for Renal Cell Carcinoma: Getting the Troops All Worked Up Translational Andrology and Urology. Dec, 2012 | Pubmed ID: 25221745 Titanium Dioxide (TiO2) Nanoparticles Preferentially Induce Cell Death in Transformed Cells in a Bak/Bax-independent Fashion PloS One. 2012 | Pubmed ID: 23185639 Cytochrome C Oxidase is Activated by the Oncoprotein Ras and is Required for A549 Lung Adenocarcinoma Growth Molecular Cancer. Aug, 2012 | Pubmed ID: 22917272 Vaccination with Embryonic Stem Cells Protects Against Lung Cancer: is a Broad-spectrum Prophylactic Vaccine Against Cancer Possible? PloS One. 2012 | Pubmed ID: 22860107 Focus on the Liver: Alcohol Use, Highly Active Antiretroviral Therapy, and Liver Disease in HIV-infected Patients Alcohol Research & Health : the Journal of the National Institute on Alcohol Abuse and Alcoholism. 2010 | Pubmed ID: 23584064 Nanomaterial Cytotoxicity is Composition, Size, and Cell Type Dependent Particle and Fibre Toxicology. Aug, 2010 | Pubmed ID: 20727197 Mitochondrial Dysfunction May Explain the Cardiomyopathy of Chronic Iron Overload Free Radical Biology & Medicine. Aug, 2010 | Pubmed ID: 20450972 Red Cells, Hemoglobin, Heme, Iron, and Atherogenesis Arteriosclerosis, Thrombosis, and Vascular Biology. Jul, 2010 | Pubmed ID: 20378845 CCR9 Mediates PI3K/AKT-dependent Antiapoptotic Signals in Prostate Cancer Cells and Inhibition of CCR9-CCL25 Interaction Enhances the Cytotoxic Effects of Etoposide International Journal of Cancer. Nov, 2010 | Pubmed ID: 20127861 The HDAC Inhibitors Trichostatin A and Suberoylanilide Hydroxamic Acid Exhibit Multiple Modalities of Benefit for the Vascular Pathobiology of Sickle Transgenic Mice Blood. Mar, 2010 | Pubmed ID: 20053759 Embryonic Vaccines Against Cancer: an Early History Experimental and Molecular Pathology. Jun, 2009 | Pubmed ID: 19171137 Supression of Hemin-mediated Oxidation of Low-density Lipoprotein and Subsequent Endothelial Reactions by Hydrogen Sulfide (H(2)S) Free Radical Biology & Medicine. Mar, 2009 | Pubmed ID: 19100829 Mitochondrial DNA Damage in Iron Overload The Journal of Biological Chemistry. Feb, 2009 | Pubmed ID: 19095657 Targeting Aspartate Aminotransferase in Breast Cancer Breast Cancer Research : BCR. 2008 | Pubmed ID: 18922152 Generation of Oxidants by Hypoxic Human Pulmonary and Coronary Smooth-muscle Cells Chest. Jun, 2008 | Pubmed ID: 18339777 Histamine Release and Fibrinogen Adsorption Mediate Acute Inflammatory Responses to Biomaterial Implants in Humans Journal of Translational Medicine. Jul, 2007 | Pubmed ID: 17603911 Virus Detection and Identification Using Random Multiplex (RT)-PCR with 3'-locked Random Primers Virology Journal. Jun, 2007 | Pubmed ID: 17598900 Dietary Copper Supplementation Reverses Hypertrophic Cardiomyopathy Induced by Chronic Pressure Overload in Mice The Journal of Experimental Medicine. Mar, 2007 | Pubmed ID: 17339407 Depletion of Ascorbic Acid Restricts Angiogenesis and Retards Tumor Growth in a Mouse Model Neoplasia (New York, N.Y.). Jan, 2007 | Pubmed ID: 17325743 Cytochrome C Oxidase Activity and Oxygen Tolerance The Journal of Biological Chemistry. Apr, 2007 | Pubmed ID: 17303578 Cytotoxic and Mutagenic Effects of Tobacco-borne Free Fatty Acids Free Radical Biology & Medicine. Jan, 2006 | Pubmed ID: 16337890 Radiation-induced Cell Death: Importance of Lysosomal Destabilization The Biochemical Journal. Aug, 2005 | Pubmed ID: 15813701 Oxygen Tolerance and Coupling of Mitochondrial Electron Transport The Journal of Biological Chemistry. Nov, 2004 | Pubmed ID: 15328348 Mitochondrial Metabolism Underlies Hyperoxic Cell Damage Free Radical Biology & Medicine. Jun, 2004 | Pubmed ID: 15135183 Interactions of Copper with Glycated Proteins: Possible Involvement in the Etiology of Diabetic Neuropathy Molecular and Cellular Biochemistry. May-Jun, 2002 | Pubmed ID: 12162426 Molecular Bases of Cellular Iron Toxicity Free Radical Biology & Medicine. May, 2002 | Pubmed ID: 11978485 Neuroprotection in Cerebral Ischemia by Neutralization of 3-aminopropanal Proceedings of the National Academy of Sciences of the United States of America. Apr, 2002 | Pubmed ID: 11943872 Isolation of Exosome-Enriched Extracellular Vesicles Carrying Granulocyte-Macrophage Colony-Stimulating Factor from Embryonic Stem Cells Shuhan Meng1,2, Aaron G. Whitt1,2,3, Allison Tu2, John W. Eaton1,2,3, Chi Li1,2,3, Kavitha Yaddanapudi4,5,6 1Department of Pharmacology and Toxicology, University of Louisville, 2Experimental Therapeutics Program, Brown Cancer Center, University of Louisville, 3Department of Medicine, University of Louisville, 4Department of Surgery, University of Louisville, 5Immuno-Oncology Program, Brown Cancer Center, University of Louisville, 6Department of Microbiology and Immunology, University of Louisville JoVE 60170 Cancer Research
Isolation of Exosome-Enriched Extracellular Vesicles Carrying Granulocyte-Macrophage Colony-Stimulating Factor from Embryonic Stem Cells Shuhan Meng1,2, Aaron G. Whitt1,2,3, Allison Tu2, John W. Eaton1,2,3, Chi Li1,2,3, Kavitha Yaddanapudi4,5,6 1Department of Pharmacology and Toxicology, University of Louisville, 2Experimental Therapeutics Program, Brown Cancer Center, University of Louisville, 3Department of Medicine, University of Louisville, 4Department of Surgery, University of Louisville, 5Immuno-Oncology Program, Brown Cancer Center, University of Louisville, 6Department of Microbiology and Immunology, University of Louisville JoVE 60170 Cancer Research
