John A. Wemmie Department of Psychiatry University of Iowa Biography Publications Institution JoVE Articles John A. Wemmie has not added a biography. If you are John A. Wemmie and would like to personalize this page please email our Author Liaison for assistance. Publications Posterior Fossa Sub-Arachnoid Cysts Observed in Patients with Bipolar Disorder: a Retrospective Cohort Study Cerebellum (London, England). May, 2022 | Pubmed ID: 35568792 Post-acquisition CO Inhalation Enhances Fear Memory and Depends on ASIC1A Frontiers in Behavioral Neuroscience. 2021 | Pubmed ID: 34776896 A Mouse Model of Bardet-Biedl Syndrome Has Impaired Fear Memory, Which is Rescued by Lithium Treatment PLoS Genetics. 04, 2021 | Pubmed ID: 33886537 Proton Exchange Magnetic Resonance Imaging: Current and Future Applications in Psychiatric Research Frontiers in Psychiatry. 2020 | Pubmed ID: 33192650 Stimulation of Posterior Thalamic Nuclei Induces Photophobic Behavior in Mice Headache. Oct, 2020 | Pubmed ID: 32750230 Comparison of TRho MRI, Glucose Metabolism, and Amyloid Burden Across the Cognitive Spectrum: A Pilot Study The Journal of Neuropsychiatry and Clinical Neurosciences. 2020 | Pubmed ID: 32283991 A Human Amygdala Site That Inhibits Respiration and Elicits Apnea in Pediatric Epilepsy JCI Insight. 03, 2020 | Pubmed ID: 32163374 The Amygdala Differentially Regulates Defensive Behaviors Evoked by CO Behavioural Brain Research. 01, 2020 | Pubmed ID: 31536735 Overexpression of ASIC1A in the Nucleus Accumbens of Rats Potentiates Cocaine-seeking Behavior Addiction Biology. 03, 2020 | Pubmed ID: 30397978 Loss of Tau and Fyn Reduces Compensatory Effects of MAP2 for Tau and Reveals a Fyn-independent Effect of Tau on Calcium Journal of Neuroscience Research. 11, 2019 | Pubmed ID: 31452242 Acid-Sensing Ion Channels: Novel Mediators of Cerebral Vascular Responses Circulation Research. 10, 2019 | Pubmed ID: 31451088 A Novel Role for Acid-sensing Ion Channels in Pavlovian Reward Conditioning Genes, Brain, and Behavior. 09, 2019 | Pubmed ID: 30375184 Attenuation of Cocaine Seeking in Rats Via Enhancement of Infralimbic Cortical Activity Using Stable Step-function Opsins Psychopharmacology. Jan, 2019 | Pubmed ID: 30003306 Alterations of the Cerebellum and Basal Ganglia in Bipolar Disorder Mood States Detected by Quantitative T1ρ Mapping Bipolar Disorders. 06, 2018 | Pubmed ID: 29316081 Impaired Sensory Processing Measured by Functional MRI in Bipolar Disorder Manic and Depressed Mood States Brain Imaging and Behavior. Jun, 2018 | Pubmed ID: 28674759 Relationship Altered Between Functional T1ρ and BOLD Signals in Bipolar Disorder Brain and Behavior. 10, 2017 | Pubmed ID: 29075562 Transient Acidosis While Retrieving a Fear-related Memory Enhances Its Lability ELife. 06, 2017 | Pubmed ID: 28650315 Extinction of Cocaine Seeking Requires a Window of Infralimbic Pyramidal Neuron Activity After Unreinforced Lever Presses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 06, 2017 | Pubmed ID: 28539416 Peripheral Inflammation During Abnormal Mood States in Bipolar I Disorder Journal of Affective Disorders. Nov, 2015 | Pubmed ID: 26339927 ASIC1A in the Bed Nucleus of the Stria Terminalis Mediates TMT-evoked Freezing Frontiers in Neuroscience. 2015 | Pubmed ID: 26257596 Breathing Inhibited When Seizures Spread to the Amygdala and Upon Amygdala Stimulation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2015 | Pubmed ID: 26180203 Eccentricity Mapping of the Human Visual Cortex to Evaluate Temporal Dynamics of Functional T1ρ Mapping Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jul, 2015 | Pubmed ID: 25966957 Brain Abnormalities in Bipolar Disorder Detected by Quantitative T1ρ Mapping Molecular Psychiatry. Feb, 2015 | Pubmed ID: 25560762 Rapid Acquisition Strategy for Functional T1ρ Mapping of the Brain Magnetic Resonance Imaging. Nov, 2014 | Pubmed ID: 25093630 The Bed Nucleus of the Stria Terminalis is Critical for Anxiety-related Behavior Evoked by CO2 and Acidosis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2014 | Pubmed ID: 25080586 Drug Abuse and the Simplest Neurotransmitter ACS Chemical Neuroscience. Sep, 2014 | Pubmed ID: 25054738 Acid-sensing Ion Channels Contribute to Synaptic Transmission and Inhibit Cocaine-evoked Plasticity Nature Neuroscience. Jun, 2014 | Pubmed ID: 24952644 Regulator of G-protein Signaling 6 (RGS6) Promotes Anxiety and Depression by Attenuating Serotonin-mediated Activation of the 5-HT(1A) Receptor-adenylyl Cyclase Axis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Apr, 2014 | Pubmed ID: 24421401 Acid-sensing Ion Channels 1a (ASIC1a) Inhibit Neuromuscular Transmission in Female Mice American Journal of Physiology. Cell Physiology. Feb, 2014 | Pubmed ID: 24336653 Localization and Behaviors in Null Mice Suggest That ASIC1 and ASIC2 Modulate Responses to Aversive Stimuli Genes, Brain, and Behavior. Feb, 2014 | Pubmed ID: 24256442 Functional T1ρ Imaging in Panic Disorder Biological Psychiatry. Jun, 2014 | Pubmed ID: 24157339 PRICKLE1 Interaction with SYNAPSIN I Reveals a Role in Autism Spectrum Disorders PloS One. 2013 | Pubmed ID: 24312498 Acid-sensing Ion Channels in Pain and Disease Nature Reviews. Neuroscience. Jul, 2013 | Pubmed ID: 23783197 Fear and Panic in Humans with Bilateral Amygdala Damage Nature Neuroscience. Mar, 2013 | Pubmed ID: 23377128 Detecting Activity-evoked PH Changes in Human Brain Proceedings of the National Academy of Sciences of the United States of America. May, 2012 | Pubmed ID: 22566645 Neurobiology of Panic and PH Chemosensation in the Brain Dialogues in Clinical Neuroscience. 2011 | Pubmed ID: 22275852 Maternal Antioxidant Blocks Programmed Cardiovascular and Behavioural Stress Responses in Adult Mice Clinical Science (London, England : 1979). Nov, 2011 | Pubmed ID: 21615331 Neonatal Leptin Administration Alters Regional Brain Volumes and Blocks Neonatal Growth Restriction-induced Behavioral and Cardiovascular Dysfunction in Male Mice Pediatric Research. May, 2011 | Pubmed ID: 21258265 Histologic Examination of the Eye of Acid-sensing Ion Channel 1a Knockout Mice International Journal of Physiology, Pathophysiology and Pharmacology. Mar, 2010 | Pubmed ID: 21383900 Amygdala Volume Correlates Positively with Fearfulness in Normal Healthy Girls Social Cognitive and Affective Neuroscience. Dec, 2010 | Pubmed ID: 20150341 ASIC1 and ASIC3 Play Different Roles in the Development of Hyperalgesia After Inflammatory Muscle Injury The Journal of Pain. Mar, 2010 | Pubmed ID: 20015700 The Amygdala is a Chemosensor That Detects Carbon Dioxide and Acidosis to Elicit Fear Behavior Cell. Nov, 2009 | Pubmed ID: 19945383 Acid-sensing Ion Channels: A New Target for Pain and CNS Diseases Current Opinion in Drug Discovery & Development. Sep, 2009 | Pubmed ID: 19736627 Role of Calcitonin Gene-related Peptide in Light-aversive Behavior: Implications for Migraine The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2009 | Pubmed ID: 19587287 Stereotactic Atlas-based Depth Electrode Localization in the Human Amygdala Stereotactic and Functional Neurosurgery. 2009 | Pubmed ID: 19556831 Acid-sensing Ion Channel-1a in the Amygdala, a Novel Therapeutic Target in Depression-related Behavior The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2009 | Pubmed ID: 19403806 Oxidant Regulated Inter-subunit Disulfide Bond Formation Between ASIC1a Subunits Proceedings of the National Academy of Sciences of the United States of America. Mar, 2009 | Pubmed ID: 19218436 The Cytoskeletal Protein Alpha-actinin Regulates Acid-sensing Ion Channel 1a Through a C-terminal Interaction The Journal of Biological Chemistry. Jan, 2009 | Pubmed ID: 19028690 Restoring Acid-sensing Ion Channel-1a in the Amygdala of Knock-out Mice Rescues Fear Memory but Not Unconditioned Fear Responses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2008 | Pubmed ID: 19091964 Seizure Termination by Acidosis Depends on ASIC1a Nature Neuroscience. Jul, 2008 | Pubmed ID: 18536711 Targeting ASIC1a Reduces Innate Fear and Alters Neuronal Activity in the Fear Circuit Biological Psychiatry. Nov, 2007 | Pubmed ID: 17662962 Acid-sensing Ion Channel 1a is a Postsynaptic Proton Receptor That Affects the Density of Dendritic Spines Proceedings of the National Academy of Sciences of the United States of America. Oct, 2006 | Pubmed ID: 17060608 Acid-sensing Ion Channels: Advances, Questions and Therapeutic Opportunities Trends in Neurosciences. Oct, 2006 | Pubmed ID: 16891000 Functional Correction of CNS Phenotypes in a Lysosomal Storage Disease Model Using Adeno-associated Virus Type 4 Vectors The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2005 | Pubmed ID: 16221840 Stomatin Modulates Gating of Acid-sensing Ion Channels The Journal of Biological Chemistry. Dec, 2004 | Pubmed ID: 15471860 Impaired Motor Performance and Learning in Glia Maturation Factor-knockout Mice Brain Research. Oct, 2004 | Pubmed ID: 15451385 Overexpression of Acid-sensing Ion Channel 1a in Transgenic Mice Increases Acquired Fear-related Behavior Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004 | Pubmed ID: 14988500 Acid-sensing Ion Channel 2 (ASIC2) Modulates ASIC1 H+-activated Currents in Hippocampal Neurons The Journal of Biological Chemistry. Apr, 2004 | Pubmed ID: 14960591 Chronic Hyperalgesia Induced by Repeated Acid Injections in Muscle is Abolished by the Loss of ASIC3, but Not ASIC1 Pain. Dec, 2003 | Pubmed ID: 14659506 Acid-sensing Ion Channel 1 is Localized in Brain Regions with High Synaptic Density and Contributes to Fear Conditioning The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2003 | Pubmed ID: 12843249 CAMP-dependent Protein Kinase Phosphorylation of the Acid-sensing Ion Channel-1 Regulates Its Binding to the Protein Interacting with C-kinase-1 Proceedings of the National Academy of Sciences of the United States of America. Feb, 2003 | Pubmed ID: 12578970 The Acid-activated Ion Channel ASIC Contributes to Synaptic Plasticity, Learning, and Memory Neuron. Apr, 2002 | Pubmed ID: 11988176 Heteromultimers of DEG/ENaC Subunits Form H+-gated Channels in Mouse Sensory Neurons Proceedings of the National Academy of Sciences of the United States of America. Feb, 2002 | Pubmed ID: 11854527 Interaction of the Synaptic Protein PICK1 (protein Interacting with C Kinase 1) with the Non-voltage Gated Sodium Channels BNC1 (brain Na+ Channel 1) and ASIC (acid-sensing Ion Channel) The Biochemical Journal. Feb, 2002 | Pubmed ID: 11802773 Modeling Human Cerebellar Development In Vitro in 2D Structure Deniz A. Madencioglu1,3,4,5, Karina A. Kruth1,3,4,5, Thomas H. Wassink1,3, Vincent A. Magnotta1,2,3,4,5, John A. Wemmie1,3,4,5, Aislinn J. Williams1,3,4,5 1Department of Psychiatry, University of Iowa, 2Department of Radiology, University of Iowa, 3Carver College of Medicine, University of Iowa, 4Iowa Neuroscience Institute, University of Iowa, 5Pappajohn Biomedical Institute, University of Iowa JoVE 64462 Neuroscience
Modeling Human Cerebellar Development In Vitro in 2D Structure Deniz A. Madencioglu1,3,4,5, Karina A. Kruth1,3,4,5, Thomas H. Wassink1,3, Vincent A. Magnotta1,2,3,4,5, John A. Wemmie1,3,4,5, Aislinn J. Williams1,3,4,5 1Department of Psychiatry, University of Iowa, 2Department of Radiology, University of Iowa, 3Carver College of Medicine, University of Iowa, 4Iowa Neuroscience Institute, University of Iowa, 5Pappajohn Biomedical Institute, University of Iowa JoVE 64462 Neuroscience
