John D. Aitchison Institute for Systems Biology Biography Publications Institution JoVE Articles John D. Aitchison has not added a biography. If you are John D. Aitchison and would like to personalize this page please email our Author Liaison for assistance. Publications An Indicator Cell Assay for Blood-based Diagnostics PloS One. 2017 | Pubmed ID: 28594877 Combining Inferred Regulatory and Reconstructed Metabolic Networks Enhances Phenotype Prediction in Yeast PLoS Computational Biology. May, 2017 | Pubmed ID: 28520713 One-Cell Doubling Evaluation by Living Arrays of Yeast, ODELAY! G3 (Bethesda, Md.). Jan, 2017 | Pubmed ID: 27856698 Co-dependence Between Trypanosome Nuclear Lamina Components in Nuclear Stability and Control of Gene Expression Nucleic Acids Research. Sep, 2016 | Pubmed ID: 27625397 Human SRMAtlas: A Resource of Targeted Assays to Quantify the Complete Human Proteome Cell. Jul, 2016 | Pubmed ID: 27453469 Severe Adult Malaria is Associated with Specific PfEMP1 Adhesion Types and High Parasite Biomass Proceedings of the National Academy of Sciences of the United States of America. Jun, 2016 | Pubmed ID: 27185931 Peroxins Pex30 and Pex29 Dynamically Associate with Reticulons to Regulate Peroxisome Biogenesis from the Endoplasmic Reticulum The Journal of Biological Chemistry. Jul, 2016 | Pubmed ID: 27129769 Systematic Analysis of Yeast Proteome Reveals Peptide Detectability Factors for Mass Spectrometry Journal of Proteomics & Bioinformatics. 2015 | Pubmed ID: 26962293 The Interactome Challenge The Journal of Cell Biology. Nov, 2015 | Pubmed ID: 26572620 Corrigendum: Pan-viral Specificity of IFN-induced Genes Reveals New Roles for CGAS in Innate Immunity Nature. Sep, 2015 | Pubmed ID: 26153856 Signaling Dynamics and Peroxisomes Current Opinion in Cell Biology. Aug, 2015 | Pubmed ID: 26042681 Rapid, Optimized Interactomic Screening Nature Methods. Jun, 2015 | Pubmed ID: 25938370 Bicluster Sampled Coherence Metric (BSCM) Provides an Accurate Environmental Context for Phenotype Predictions BMC Systems Biology. 2015 | Pubmed ID: 25881257 Systems Cell Biology The Journal of Cell Biology. Sep, 2014 | Pubmed ID: 25225336 Predicting Antidisease Immunity Using Proteome Arrays and Sera from Children Naturally Exposed to Malaria Molecular & Cellular Proteomics : MCP. Oct, 2014 | Pubmed ID: 25023128 Quantitative Proteomic Analysis of Host-virus Interactions Reveals a Role for Golgi Brefeldin A Resistance Factor 1 (GBF1) in Dengue Infection Molecular & Cellular Proteomics : MCP. Nov, 2014 | Pubmed ID: 24855065 The Multifunctional Nuclear Pore Complex: a Platform for Controlling Gene Expression Current Opinion in Cell Biology. Jun, 2014 | Pubmed ID: 24657998 An Evolutionarily Conserved RNase-based Mechanism for Repression of Transcriptional Positive Autoregulation Molecular Microbiology. Apr, 2014 | Pubmed ID: 24612392 Nuclear Pore Complex Evolution: a Trypanosome Mlp Analogue Functions in Chromosomal Segregation but Lacks Transcriptional Barrier Activity Molecular Biology of the Cell. May, 2014 | Pubmed ID: 24600046 Pan-viral Specificity of IFN-induced Genes Reveals New Roles for CGAS in Innate Immunity Nature. Jan, 2014 | Pubmed ID: 24284630 Molecular Mechanisms of System Responses to Novel Stimuli Are Predictable from Public Data Nucleic Acids Research. Feb, 2014 | Pubmed ID: 24185701 Peroxisomes Take Shape Nature Reviews. Molecular Cell Biology. Dec, 2013 | Pubmed ID: 24263361 PhosphoChain: a Novel Algorithm to Predict Kinase and Phosphatase Networks from High-throughput Expression Data Bioinformatics (Oxford, England). Oct, 2013 | Pubmed ID: 23832245 Multifunctional Double-negative T Cells in Sooty Mangabeys Mediate T-helper Functions Irrespective of SIV Infection PLoS Pathogens. 2013 | Pubmed ID: 23825945 A Role for the Nucleoporin Nup170p in Chromatin Structure and Gene Silencing Cell. Feb, 2013 | Pubmed ID: 23452847 有针对性的质谱法测定的转录因子 DNA 相互作用系统的衡量方法标识候选基因调控蛋白。 Proceedings of the National Academy of Sciences of the United States of America. Feb, 2013 | Pubmed ID: 23388641 Metallochaperones Regulate Intracellular Copper Levels PLoS Computational Biology. 2013 | Pubmed ID: 23349626 Global Analysis of Condition-specific Subcellular Protein Distribution and Abundance Molecular & Cellular Proteomics : MCP. May, 2013 | Pubmed ID: 23349476 A FOXO3-IRF7 Gene Regulatory Circuit Limits Inflammatory Sequelae of Antiviral Responses Nature. Oct, 2012 | Pubmed ID: 22982991 Asymmetric Positive Feedback Loops Reliably Control Biological Responses Molecular Systems Biology. Apr, 2012 | Pubmed ID: 22531117 NUP-1 是大卷线圈 Nucleoskeletal 蛋白在锥虫与拉明类似的职能。 PLoS Biology. 2012 | Pubmed ID: 22479148 The Yeast Nuclear Pore Complex and Transport Through It Genetics. Mar, 2012 | Pubmed ID: 22419078 母体 FAIMS 分馏提供蛋白质组覆盖的肝素复杂蛋白质摘要显著上升。 Molecular & Cellular Proteomics : MCP. Dec, 2011 | Pubmed ID: 22186714 要使高吞吐量流式细胞形态矫正回归模型方法。 Molecular Systems Biology. 2011 | Pubmed ID: 21952134 生物分子网络动力学的数学建模。 Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21877294 动态的转录调控网络结构的统计分析。 Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21877289 响应能力与环境线索的生物分子系统答复中的噪声抑制之间的权衡。 PLoS Computational Biology. Jun, 2011 | Pubmed ID: 21738459 Peroxin Pex34p 与 Pex11 的过氧化物分区的蛋白质,以规管在酵母中的过氧化物酶体增殖人口家庭的功能。 Molecular Biology of the Cell. May, 2011 | Pubmed ID: 21441307 更快、 定量和准确的前体购置独立从离子计数。 Analytical Chemistry. Mar, 2011 | Pubmed ID: 21341720 核信封中基因组组织及其基因表达的作用。 Wiley Interdisciplinary Reviews. Systems Biology and Medicine. Mar-Apr, 2011 | Pubmed ID: 21305702 环境响应转录因子将杂交元素绑定和调节基因沉默。 Molecular Systems Biology. Jan, 2011 | Pubmed ID: 21206489 沙门菌毒力因子西法在酵母中的表达改变过氧化物酶体的 Rho1 活动。 Molecular Biology of the Cell. Oct, 2010 | Pubmed ID: 20739463 全基因组分析的过氧化物酶体生物发生产生影响的手段。 PloS One. 2010 | Pubmed ID: 20694151 QTIPS: 无监督测定同位素的氨基酸分布在 SILAC 实验中一种新方法。 Journal of the American Society for Mass Spectrometry. Aug, 2010 | Pubmed ID: 20451407 综合磷酸化蛋白质组分析的信号传递网络理事养分的反应和过氧化物酶体感应。 Molecular & Cellular Proteomics : MCP. Sep, 2010 | Pubmed ID: 20395639 杯杜松子酒议案显示复制叉级数是非常统一整个酵母基因组。 Molecular Systems Biology. 2010 | Pubmed ID: 20212525 系统细胞生物学的有丝分裂的主轴。 The Journal of Cell Biology. Jan, 2010 | Pubmed ID: 20065087 在 Gpd1p 中的单元格应激反应的亚细胞分布的动态变化。 The Journal of Biological Chemistry. Feb, 2010 | Pubmed ID: 20026609 组蛋白伴侣 Chz1p 规定了 H2B 泛和杂交抗沉默。 Nucleic Acids Research. Mar, 2010 | Pubmed ID: 20008511 确定性和随机模型的基因调控网络。 Methods in Enzymology. 2009 | Pubmed ID: 19897099 Karyopherin Kap123p 微管稳定中发挥的作用。 Traffic (Copenhagen, Denmark). Nov, 2009 | Pubmed ID: 19761543 过氧化物酶体肌球蛋白驱动增殖酿酒酵母中的分区。 The Journal of Cell Biology. Aug, 2009 | Pubmed ID: 19687257 AAA ATPase 蛋白质 Yta7 的非规范化 Bromodomain 指示染色体定位和屏障染色质活动。 Molecular and Cellular Biology. Sep, 2009 | Pubmed ID: 19581291 组蛋白 H2A Variant 类型的值的作用。Z/Htz1p 在 TBP 征聘、 染色质动力学和油酸敏感基因的表达调控。 Molecular and Cellular Biology. May, 2009 | Pubmed ID: 19273605 过氧化物酶体动态调节。 Current Opinion in Cell Biology. Feb, 2009 | Pubmed ID: 19188056 控制转录变异性的重叠前馈规管的图案。 Biophysical Journal. Oct, 2008 | Pubmed ID: 18621837 在系统生物学研究所的系统生物学。 Briefings in Functional Genomics & Proteomics. Jul, 2008 | Pubmed ID: 18579616 酿酒酵母 Yta7 调节组蛋白基因的表达。 Genetics. May, 2008 | Pubmed ID: 18493054 全基因组分析的信令网络调节脂肪酸诱导基因表达和细胞器的生物发生。 The Journal of Cell Biology. Apr, 2008 | Pubmed ID: 18426976 亚细胞组分的同位素编码标签来标识善意组件的细胞器: 过氧化物酶体中的示例。 Methods in Molecular Biology (Clifton, N.J.). 2008 | Pubmed ID: 18370030 细胞生物学: 孔隙拼图。 Nature. Nov, 2007 | Pubmed ID: 18046388 综合分析各种核糖核蛋白复合物。 Nature Methods. Nov, 2007 | Pubmed ID: 17922018 由组合控制协调对脂肪酸的转录反应。 Molecular Systems Biology. 2007 | Pubmed ID: 17551510 在 Septins 的受规管的 Sumoylation Karyopherins 的作用。 The Journal of Cell Biology. Apr, 2007 | Pubmed ID: 17403926 Yng1 博士手指绑定到在 K4 H3 Trimethylated 促进有针对性 ORFs 子集时转录和 K14 H3 NuA3 帽子活动。 Molecular Cell. Dec, 2006 | Pubmed ID: 17157260 学习核蛋白在酵母中的导入。 Methods (San Diego, Calif.). Aug, 2006 | Pubmed ID: 16979507 双反馈回路在 GAL Regulon 压制在酵母细胞的异质性。 Nature Genetics. Sep, 2006 | Pubmed ID: 16936734 表达及功能分析揭示不同基因类参与脂肪酸代谢的。 Molecular Systems Biology. 2006 | Pubmed ID: 16738555 过氧化物膜蛋白 Inp2p 是肌球蛋白 V 电机 Myo2p 的酿酒酵母的过氧化物酶体特异性受体。 Developmental Cell. May, 2006 | Pubmed ID: 16678774 Pex19p Pex30p 和 Pex32p 在其过氧化物本地化所需的区域绑定但又独立于其过氧化物的目标信号。 The Journal of Biological Chemistry. May, 2006 | Pubmed ID: 16551610 酵母酿酒酵母 Dynamin 样蛋白 Vps1p 将与过氧化物酶体 Pex19p 依赖的方式相关联。 The Journal of Biological Chemistry. May, 2006 | Pubmed ID: 16520372 移动 Nucleoporin Nup2p 和内源性人大介导的转录调控染色质绑定 Prp20p 函数。 The Journal of Cell Biology. Dec, 2005 | Pubmed ID: 16365162 数据集成系统生物学的方法。 Proceedings of the National Academy of Sciences of the United States of America. Nov, 2005 | Pubmed ID: 16301537 系统生物学数据集成方法: 实验验证。 Proceedings of the National Academy of Sciences of the United States of America. Nov, 2005 | Pubmed ID: 16301536 Mad1p 与核运输机械在酵母酿酒酵母中的交互作用。 Molecular Biology of the Cell. Sep, 2005 | Pubmed ID: 16000377 Inp1p 是在酿酒酵母中的过氧化物酶体继承所需的过氧化物膜蛋白。 The Journal of Cell Biology. Jun, 2005 | Pubmed ID: 15928207 蛋白质组学和基因组表征染色质在边界处。 The Journal of Cell Biology. Apr, 2005 | Pubmed ID: 15824130 Nop53p 是一本小说核仁 60 年代核糖体亚基生物发生蛋白。 The Biochemical Journal. Jun, 2005 | Pubmed ID: 15686447 定量质谱法中的过氧化物酶体的膜上的肌动蛋白组织蛋白 Rho1p 显示作用。 The Journal of Cell Biology. Dec, 2004 | Pubmed ID: 15596542 Karyopherin 货物的表征揭示了 Kap121p 介导核导入的唯一机制。 Molecular and Cellular Biology. Oct, 2004 | Pubmed ID: 15367670 Pex30p、 Pex31p 和 Pex32p 组成过氧化物积分膜蛋白调节的过氧化物酶体的大小和数目在酿酒酵母中的家庭。 Molecular Biology of the Cell. Feb, 2004 | Pubmed ID: 14617799 细胞周期调节控制的核孔复合体改建的运输。 Cell. Dec, 2003 | Pubmed ID: 14697200 虚拟浇注与核运输: 孔图片。 Trends in Cell Biology. Dec, 2003 | Pubmed ID: 14624840 Pex11 相关蛋白的过氧化物酶体动力学: 新型 Peroxin Pex27p 控制的过氧化物酶体的大小和数目在酿酒酵母中的发挥的作用。 Molecular Biology of the Cell. Oct, 2003 | Pubmed ID: 14517321 Utp8p 是酿酒酵母细胞的核 TRNA 出口机械重要组成部分核内包涵。 The Journal of Biological Chemistry. Aug, 2003 | Pubmed ID: 12794079 清单的洞见。 The Journal of Cell Biology. May, 2003 | Pubmed ID: 12743099 YHR150w 和 YDR479c 编码过氧化物积分膜蛋白参与的过氧化物酶体数量、 大小和分布在酿酒酵母中的调节。 The Journal of Cell Biology. Apr, 2003 | Pubmed ID: 12707309 中核 Karyopherins 孔生物发生: Kap121p 中核孔复合物的 Nup53p 程序集的作用。 The Journal of Cell Biology. Oct, 2002 | Pubmed ID: 12403813 由气相分馏接近完整的过氧化物酶体的表征。 Electrophoresis. Sep, 2002 | Pubmed ID: 12298092 分析以找出相关的过氧化物酶体组装和功能基因的转录过程。 The Journal of Cell Biology. Jul, 2002 | Pubmed ID: 12135984 Kap121p 介导核导入是所必需的酵母交配和细胞分化。 Molecular and Cellular Biology. Apr, 2002 | Pubmed ID: 11909949 紧张的时刻,核信封。 Cell. Feb, 2002 | Pubmed ID: 11853664 ODELAY:用于酵母生长多参数定量的大规模方法 Thurston Herricks1, Fred D. Mast1,2, Song Li1, John D. Aitchison1,2 1Institute for Systems Biology, 2Center for Infectious Disease Research JoVE 55879 Biology 脂肪酸定量磷酸化刺激酿酒酵母 Ramsey A. Saleem1, John D. Aitchison1 1Institute for Systems Biology JoVE 1474 Biology
ODELAY:用于酵母生长多参数定量的大规模方法 Thurston Herricks1, Fred D. Mast1,2, Song Li1, John D. Aitchison1,2 1Institute for Systems Biology, 2Center for Infectious Disease Research JoVE 55879 Biology
脂肪酸定量磷酸化刺激酿酒酵母 Ramsey A. Saleem1, John D. Aitchison1 1Institute for Systems Biology JoVE 1474 Biology