John S. Condeelis Cancer Dormancy and Tumor Microenvironment Institute Albert Einstein College of Medicine/Montefiore Medical Center Biography Publications Institution JoVE Articles John S. Condeelis has not added a biography. If you are John S. Condeelis and would like to personalize this page please email our Author Liaison for assistance. Publications Racial Disparity in Tumor Microenvironment and Distant Recurrence in Residual Breast Cancer After Neoadjuvant Chemotherapy NPJ Breast Cancer. Jun, 2023 | Pubmed ID: 37311792 Macrophages Promote Tumor Cell Extravasation Across an Endothelial Barrier Through Thin Membranous Connections Cancers. Mar, 2023 | Pubmed ID: 37046751 Cooperative NF-κB and Notch1 Signaling Promotes Macrophage-mediated MenaINV Expression in Breast Cancer Breast Cancer Research : BCR. Apr, 2023 | Pubmed ID: 37024946 Intravital Imaging to Study Cancer Progression and Metastasis Nature Reviews. Cancer. Jan, 2023 | Pubmed ID: 36385560 Interleukin 4 Controls the Pro-Tumoral Role of Macrophages in Mammary Cancer Pulmonary Metastasis in Mice Cancers. Sep, 2022 | Pubmed ID: 36077870 Assessment of MRI to Estimate Metastatic Dissemination Risk and Prometastatic Effects of Chemotherapy NPJ Breast Cancer. Sep, 2022 | Pubmed ID: 36056005 Racial Disparity in Distant Recurrence-free Survival in Patients with Localized Breast Cancer: A Pooled Analysis of National Surgical Adjuvant Breast and Bowel Project Trials Cancer. Jul, 2022 | Pubmed ID: 35578919 Combining TMEM Doorway Score and Mena Score Improves the Prediction of Distant Recurrence Risk in HR+/HER2- Breast Cancer Patients Cancers. Apr, 2022 | Pubmed ID: 35565297 Primary Tumor Associated Macrophages Activate Programs of Invasion and Dormancy in Disseminating Tumor Cells Nature Communications. Feb, 2022 | Pubmed ID: 35110548 Validation of an Automated Quantitative Digital Pathology Approach for Scoring TMEM, a Prognostic Biomarker for Metastasis Cancers. Mar, 2020 | Pubmed ID: 32244564 Black Race and Distant Recurrence After Neoadjuvant or Adjuvant Chemotherapy in Breast Cancer Clinical & Experimental Metastasis. 10, 2018 | Pubmed ID: 30136072 Signatures of Breast Cancer Metastasis at a Glance Journal of Cell Science. May, 2016 | Pubmed ID: 27084578 GPCR Signaling Mediates Tumor Metastasis Via PI3Kβ Cancer Research. May, 2016 | Pubmed ID: 27013201 3-D Individual Cell Based Computational Modeling of Tumor Cell-macrophage Paracrine Signaling Mediated by EGF and CSF-1 Gradients Integrative Biology : Quantitative Biosciences from Nano to Macro. Jan, 2016 | Pubmed ID: 26686751 Characterization of the Expression of the Pro-metastatic Mena(INV) Isoform During Breast Tumor Progression Clinical & Experimental Metastasis. Mar, 2016 | Pubmed ID: 26680363 PTP1B-dependent Regulation of Receptor Tyrosine Kinase Signaling by the Actin-binding Protein Mena Molecular Biology of the Cell. Nov, 2015 | Pubmed ID: 26337385 Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage-Derived VEGFA Cancer Discovery. Sep, 2015 | Pubmed ID: 26269515 Menacalc, a Quantitative Method of Metastasis Assessment, As a Prognostic Marker for Axillary Node-negative Breast Cancer BMC Cancer. 2015 | Pubmed ID: 26112005 Invasive Breast Carcinoma Cells from Patients Exhibit MenaINV- and Macrophage-dependent Transendothelial Migration Science Signaling. Nov, 2014 | Pubmed ID: 25429076 An in Vitro One-dimensional Assay to Study Growth Factor-regulated Tumor Cell-macrophage Interaction Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24908299 Metastatic Cells: Moving Onco-targets Oncotarget. Jun, 2014 | Pubmed ID: 24907202 Tumor Microenvironment of Metastasis and Risk of Distant Metastasis of Breast Cancer Journal of the National Cancer Institute. Aug, 2014 | Pubmed ID: 24895374 Invadopodia in Context Cell Adhesion & Migration. 2014 | Pubmed ID: 24713806 Spatial Regulation of Tumor Cell Protrusions by RhoC Cell Adhesion & Migration. 2014 | Pubmed ID: 24642482 Filamin A Interacting Protein 1-like Inhibits WNT Signaling and MMP Expression to Suppress Cancer Cell Invasion and Metastasis International Journal of Cancer. Jul, 2014 | Pubmed ID: 24327474 Intravital Multiphoton Imaging Reveals Multicellular Streaming As a Crucial Component of in Vivo Cell Migration in Human Breast Tumors Intravital. Apr, 2013 | Pubmed ID: 25013744 Wiskott-Aldrich Syndrome Protein Regulates Leukocyte-dependent Breast Cancer Metastasis Cell Reports. Aug, 2013 | Pubmed ID: 23911287 Dysregulation of PAD4-mediated Citrullination of Nuclear GSK3β Activates TGF-β Signaling and Induces Epithelial-to-mesenchymal Transition in Breast Cancer Cells Proceedings of the National Academy of Sciences of the United States of America. Jul, 2013 | Pubmed ID: 23818587 Development Path and Current Status of the NANIVID: a New Device for Cancer Cell Studies Journal of Micro/nanolithography, MEMS, and MOEMS : JM3. Mar, 2012 | Pubmed ID: 25419258 Reconstitution of in Vivo Macrophage-tumor Cell Pairing and Streaming Motility on One-dimensional Micro-patterned Substrates Intravital. Jul, 2012 | Pubmed ID: 24634804 Selective Gene-expression Profiling of Migratory Tumor Cells in Vivo Predicts Clinical Outcome in Breast Cancer Patients Breast Cancer Research : BCR. 2012 | Pubmed ID: 23113900 Quantitative Assessment of Invasive Mena Isoforms (Menacalc) As an Independent Prognostic Marker in Breast Cancer Breast Cancer Research : BCR. 2012 | Pubmed ID: 22971274 A FRET-facilitated Photoswitching Using an Orange Fluorescent Protein with the Fast Photoconversion Kinetics Journal of the American Chemical Society. Sep, 2012 | Pubmed ID: 22900938 Three-dimensional Microfluidic Model for Tumor Cell Intravasation and Endothelial Barrier Function Proceedings of the National Academy of Sciences of the United States of America. Aug, 2012 | Pubmed ID: 22869695 预测乳腺癌血行传播的相关免疫组织化学和细胞学检测方法。 The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Jan, 2012 | Pubmed ID: 22215635 反对 CXCR4 和 CXCR7 在乳腺癌转移中的作用。 Breast Cancer Research : BCR. Dec, 2011 | Pubmed ID: 22152016 EMT 驱动替代拼接程序发生在人类乳腺癌和调节细胞表型。 PLoS Genetics. Aug, 2011 | Pubmed ID: 21876675 Photoswitchable 向远红色橙色荧光蛋白,PSmOrange。 Nature Methods. Sep, 2011 | Pubmed ID: 21804536 趋化性癌。 Nature Reviews. Cancer. Aug, 2011 | Pubmed ID: 21779009 中东和北非创 (MenaINV) 促进小鼠模型的乳腺癌细胞流动力及内耳迁移。 Journal of Cell Science. Jul, 2011 | Pubmed ID: 21670198 中东和北非创 (Mena(INV)) 和 Mena11a 异构体播放不同的角色在乳腺肿瘤细胞凝聚力和蒙医关联。 Clinical & Experimental Metastasis. Aug, 2011 | Pubmed ID: 21484349 中东和北非虚延缓肿瘤的形成过程,并降低多瘤中间 T 转基因小鼠乳腺肿瘤转移。 Breast Cancer Research : BCR. 2010 | Pubmed ID: 21108830 细胞迁移研究新趋化设备。 Integrative Biology : Quantitative Biosciences from Nano to Macro. Nov, 2010 | Pubmed ID: 20938544 AACR 特别会议上皮间质的转型与癌症进展及治疗。 Cancer Research. Oct, 2010 | Pubmed ID: 20823151 巨噬细胞,促进肿瘤侵袭基因表达分析支持作用 Wnt 信号在调解他们在原发性乳腺肿瘤中的活动。 Journal of Immunology (Baltimore, Md. : 1950). Jan, 2010 | Pubmed ID: 20018620 入侵人类乳腺癌细胞体内需要涉及集落刺激因子-1 受体的旁分泌和自分泌环路。 Cancer Research. Dec, 2009 | Pubmed ID: 19934330 差动提高乳腺癌癌细胞运动和转移的螺旋和类 IA 磷脂酰肌醇 3-激酶激酶域突变。 Cancer Research. Dec, 2009 | Pubmed ID: 19903845 人类乳房癌转移的肿瘤微环境: 潜在的预后标记链接到血源性传播。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2009 | Pubmed ID: 19318480 识别特定的入侵期间入侵体内拼接中东和北非目前乳腺肿瘤细胞的细胞骨架蛋白的变种。 Clinical & Experimental Metastasis. 2009 | Pubmed ID: 18985426 中东和北非入侵鼻息肉增强表皮生长因子诱导肿瘤细胞浸润和转移。 Developmental Cell. Dec, 2008 | Pubmed ID: 19081071 机制和地方蛋白质合成在哺乳动物细胞中的细胞的角色。 Current Opinion in Cell Biology. Apr, 2008 | Pubmed ID: 18378131 RhoA/岩介导 Cdc42 和 Rac1 依赖椎间盘突出 MTLn3 癌细胞之间切换。 Experimental Cell Research. Apr, 2008 | Pubmed ID: 18316075 生活系统与单誊本决议中的影像实时基因表达: 构造设计和成像系统设置。 CSH Protocols. 2007 | Pubmed ID: 21356986 生活系统与单誊本决议中的影像实时基因表达: 单 MRNA 粒子追踪与基于 ImageJ 的分析。 CSH Protocols. 2007 | Pubmed ID: 21356980 生活系统与单誊本决议中的影像实时基因表达: 图像分析单个 MRNA 成绩单。 CSH Protocols. 2007 | Pubmed ID: 21356979 影像生活酵母实时基因的表达。 CSH Protocols. 2007 | Pubmed ID: 21356978 影像学在哺乳动物细胞与单誊本决议中实时的基因表达。 CSH Protocols. 2007 | Pubmed ID: 21356977 表皮生长因子诱导 PIP2 水解释放,并激活 Cofilin 癌细胞在当地。 The Journal of Cell Biology. Dec, 2007 | Pubmed ID: 18086920 ZBP1 可以提高细胞极性,并降低趋化性。 Journal of Cell Science. Sep, 2007 | Pubmed ID: 17878234 Cdc42 是表皮生长因子刺激椎间盘突出和动力的 MTLn3 肝癌细胞所必需的。 Journal of Cell Science. Oct, 2007 | Pubmed ID: 17855387 Ras 和 Rac PI 依赖激酶-3 的椎间盘突出在表皮生长因子刺激细胞迁移过程中的不同角色。 Journal of Cell Science. Sep, 2007 | Pubmed ID: 17698922 协调的监管的途径增强的细胞运动和趋化性被守恒在大鼠和小鼠乳腺肿瘤。 Cancer Research. Apr, 2007 | Pubmed ID: 17440055 HMena (新设) 和其接头备选案文 HMena + 第 11a 条的分子克隆: 表皮生长因子增加它们的表情和刺激 HMena + 第 11a 条在乳腺癌细胞株的磷酸化。 Cancer Research. Mar, 2007 | Pubmed ID: 17363586 岩石和肌球蛋白依赖矩阵变形使蛋白酶独立肿瘤细胞入侵体内。 Current Biology : CB. Aug, 2006 | Pubmed ID: 16890527 表皮生长因子的响应 Cofilin 活动的开始是从 Cofilin 磷酸化和脱氮除磷癌细胞中的解耦。 Journal of Cell Science. Jul, 2006 | Pubmed ID: 16803871 Cofilin 该活动的状态直接关乎入侵、 术前和乳腺肿瘤转移。 The Journal of Cell Biology. May, 2006 | Pubmed ID: 16651380 巨噬细胞促进入侵的乳腺癌细胞通过集落刺激因子-1/表皮生长因子旁分泌循环。 Cancer Research. Jun, 2005 | Pubmed ID: 15958574 肿瘤细胞陷入的入侵行为: 其战略以增强的细胞运动。 Trends in Cell Biology. Mar, 2005 | Pubmed ID: 15752977 鉴定和测试的浸润癌内原发性乳腺肿瘤细胞的基因表达签名。 Cancer Research. Dec, 2004 | Pubmed ID: 15574765 乳腺癌细胞的趋化性原发性肿瘤从孤立显示增加的生存与化疗耐。 Cancer Research. Nov, 2004 | Pubmed ID: 15520165 P110beta 的过量表达但不是 P110alpha 鼻息肉 PI 3-激酶抑制乳腺癌细胞中的动力。 Cell Motility and the Cytoskeleton. Nov, 2004 | Pubmed ID: 15468162 Cofilin 促进肌动蛋白的聚合,并定义细胞运动的方向。 Science (New York, N.Y.). Apr, 2004 | Pubmed ID: 15118165 基因表达分析原发性乳腺肿瘤的鼠标从收集的趋化性的创细胞数量很少。 BMC Biotechnology. Aug, 2003 | Pubmed ID: 12914671 绿色荧光蛋白基因表达的转基因小鼠乳腺肿瘤细胞乳腺成像。 Cancer Research. Dec, 2002 | Pubmed ID: 12499251 转移性原发性乳腺肿瘤相关基因表达谱揭示的分子分析中的单个单元格行为。 Cancer Research. Nov, 2002 | Pubmed ID: 12414658 锁定蛋白激酶受规管的新战略。 Journal of the American Chemical Society. Mar, 2002 | Pubmed ID: 11890784 Author Spotlight: Decoding Metastasis-to-Metastasis Seeding Using a New In Vivo Technique for Tracking Breast Cancer Spread (Video) | JoVE Madeline Friedman-DeLuca1,2, Prachiben P. Patel1,2, Burcu Karadal-Ferrena1,2, Nicole D. Barth1,2, Camille L. Duran1,2, Xianjun Ye1,2,3, Michael Papanicolaou2,4, John S. Condeelis2,3,4,5,6,7, Maja H. Oktay1,2,3,5,6,7, Lucia Borriello*1,2,8, David Entenberg*1,2,3,5,6 1Department of Pathology, Albert Einstein College of Medicine/Montefiore Medical Center, 2Cancer Dormancy and Tumor Microenvironment Institute, Albert Einstein College of Medicine/Montefiore Medical Center, 3Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine/Montefiore Medical Center, 4Department of Cell Biology, Albert Einstein College of Medicine/Montefiore Medical Center, 5Montefiore Einstein Cancer Center, Albert Einstein College of Medicine/Montefiore Medical Center, 6Integrated Imaging Program for Cancer Research, Albert Einstein College of Medicine/Montefiore Medical Center, 7Department of Surgery, Albert Einstein College of Medicine/Montefiore Medical Center, 8Department of Cancer and Cellular Biology, Lewis Katz School of Medicine, Fox Chase Cancer Center JoVE 65732 Cancer Research 长期高分辨率活体显微镜在肺与真空稳定成像窗口 Carolina Rodriguez-Tirado1, Takanori Kitamura5, Yu Kato1,2, Jeffery W. Pollard1,2,5, John S. Condeelis3,4, David Entenberg3,4 1Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, 2Department of Obstetrics/Gynecology and Woman’s Health, Albert Einstein College of Medicine, 3Department of Anatomy & Structural Biology, Albert Einstein College of Medicine, 4Gruss-Lipper Biophotonics Center Integrated Imaging Program, Albert Einstein College of Medicine, 5Medical Research Council Centre for Reproductive Health, Queen’s Medical Research Institute, University of Edinburgh Cancer Research 实时多细胞动力学延长时间推移活体成像在肿瘤微环境 Allison S. Harney1,2,3,4, Yarong Wang1,3, John S. Condeelis1,3,4, David Entenberg1,3,4 1Department of Anatomy & Structural Biology, Albert Einstein College of Medicine, 2Department of Radiology, Albert Einstein College of Medicine, 3Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine, 4Integrated Imaging Program, Albert Einstein College of Medicine JoVE 54042 Medicine
Author Spotlight: Decoding Metastasis-to-Metastasis Seeding Using a New In Vivo Technique for Tracking Breast Cancer Spread (Video) | JoVE Madeline Friedman-DeLuca1,2, Prachiben P. Patel1,2, Burcu Karadal-Ferrena1,2, Nicole D. Barth1,2, Camille L. Duran1,2, Xianjun Ye1,2,3, Michael Papanicolaou2,4, John S. Condeelis2,3,4,5,6,7, Maja H. Oktay1,2,3,5,6,7, Lucia Borriello*1,2,8, David Entenberg*1,2,3,5,6 1Department of Pathology, Albert Einstein College of Medicine/Montefiore Medical Center, 2Cancer Dormancy and Tumor Microenvironment Institute, Albert Einstein College of Medicine/Montefiore Medical Center, 3Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine/Montefiore Medical Center, 4Department of Cell Biology, Albert Einstein College of Medicine/Montefiore Medical Center, 5Montefiore Einstein Cancer Center, Albert Einstein College of Medicine/Montefiore Medical Center, 6Integrated Imaging Program for Cancer Research, Albert Einstein College of Medicine/Montefiore Medical Center, 7Department of Surgery, Albert Einstein College of Medicine/Montefiore Medical Center, 8Department of Cancer and Cellular Biology, Lewis Katz School of Medicine, Fox Chase Cancer Center JoVE 65732 Cancer Research
长期高分辨率活体显微镜在肺与真空稳定成像窗口 Carolina Rodriguez-Tirado1, Takanori Kitamura5, Yu Kato1,2, Jeffery W. Pollard1,2,5, John S. Condeelis3,4, David Entenberg3,4 1Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, 2Department of Obstetrics/Gynecology and Woman’s Health, Albert Einstein College of Medicine, 3Department of Anatomy & Structural Biology, Albert Einstein College of Medicine, 4Gruss-Lipper Biophotonics Center Integrated Imaging Program, Albert Einstein College of Medicine, 5Medical Research Council Centre for Reproductive Health, Queen’s Medical Research Institute, University of Edinburgh Cancer Research
实时多细胞动力学延长时间推移活体成像在肿瘤微环境 Allison S. Harney1,2,3,4, Yarong Wang1,3, John S. Condeelis1,3,4, David Entenberg1,3,4 1Department of Anatomy & Structural Biology, Albert Einstein College of Medicine, 2Department of Radiology, Albert Einstein College of Medicine, 3Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine, 4Integrated Imaging Program, Albert Einstein College of Medicine JoVE 54042 Medicine