John W.R. Schwabe Department of Biochemistry University of Leicester Biography Publications Institution JoVE Articles John W.R. Schwabe has not added a biography. If you are John W.R. Schwabe and would like to personalize this page please email our Author Liaison for assistance. Publications Histone Deacetylase (HDAC) 1 and 2 Are Essential for Accurate Cell Division and the Pluripotency of Embryonic Stem Cells Proceedings of the National Academy of Sciences of the United States of America. Jul, 2014 | Pubmed ID: 24958871 The Ansamycin Antibiotic, Rifamycin SV, Inhibits BCL6 Transcriptional Repression and Forms a Complex with the BCL6-BTB/POZ Domain PloS One. 2014 | Pubmed ID: 24595451 An Evolving Understanding of Nuclear Receptor Coregulator Proteins Journal of Molecular Endocrinology. Dec, 2013 | Pubmed ID: 24203923 Mzt1/Tam4, a Fission Yeast MOZART1 Homologue, is an Essential Component of the γ-tubulin Complex and Directly Interacts with GCP3(Alp6) Molecular Biology of the Cell. Nov, 2013 | Pubmed ID: 24006493 Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates Molecular Cell. Jul, 2013 | Pubmed ID: 23791785 A Death Effector Domain Chain DISC Model Reveals a Crucial Role for Caspase-8 Chain Assembly in Mediating Apoptotic Cell Death Molecular Cell. Jul, 2012 | Pubmed ID: 22683266 Structure of HDAC3 Bound to Co-repressor and Inositol Tetraphosphate Nature. Jan, 2012 | Pubmed ID: 22230954 A Mutation in the Thyroid Hormone Receptor Alpha Gene The New England Journal of Medicine. Jan, 2012 | Pubmed ID: 22168587 Nuclear Hormone Receptor Co-repressors: Structure and Function Molecular and Cellular Endocrinology. Jan, 2012 | Pubmed ID: 21925568 보험이 종속 E3 리가 인식 단백 수용 체의 타겟된 저하에 대 한 보존된 메커니즘입니다 Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011 | Pubmed ID: 22109552 The IDOL-UBE2D Complex Mediates Sterol-dependent Degradation of the LDL Receptor Genes & Development. Jun, 2011 | Pubmed ID: 21685362 Structural Basis for the Assembly of the SMRT/NCoR Core Transcriptional Repression Machinery Nature Structural & Molecular Biology. Feb, 2011 | Pubmed ID: 21240272 Negative Regulation by Nuclear Receptors: a Plethora of Mechanisms Trends in Endocrinology and Metabolism: TEM. Mar, 2011 | Pubmed ID: 21196123 Comparison of the Molecular Consequences of Different Mutations at Residue 754 and 690 of the Androgen Receptor (AR) and Androgen Insensitivity Syndrome (AIS) Phenotype Clinical Endocrinology. Aug, 2009 | Pubmed ID: 19178528 Structural Basis for the Activation of PPARgamma by Oxidized Fatty Acids Nature Structural & Molecular Biology. Sep, 2008 | Pubmed ID: 19172745 Structural Insights into the Interaction and Activation of Histone Deacetylase 3 by Nuclear Receptor Corepressors Proceedings of the National Academy of Sciences of the United States of America. Apr, 2005 | Pubmed ID: 15837933 Identification of a Novel Co-regulator Interaction Surface on the Ligand Binding Domain of Nurr1 Using NMR Footprinting The Journal of Biological Chemistry. Dec, 2004 | Pubmed ID: 15456745 Mechanism of the Nuclear Receptor Molecular Switch Trends in Biochemical Sciences. Jun, 2004 | Pubmed ID: 15276186 Nuclear Receptors: the Evolution of Diversity Science's STKE : Signal Transduction Knowledge Environment. Jan, 2004 | Pubmed ID: 14747695 Tyrosine Agonists Reverse the Molecular Defects Associated with Dominant-negative Mutations in Human Peroxisome Proliferator-activated Receptor Gamma Endocrinology. Apr, 2004 | Pubmed ID: 14657011 Molecular Determinants of the Balance Between Co-repressor and Co-activator Recruitment to the Retinoic Acid Receptor The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12917445 A Conserved Structural Motif Reveals the Essential Transcriptional Repression Function of Spen Proteins and Their Role in Developmental Signaling Genes & Development. Aug, 2003 | Pubmed ID: 12897056 A Dynamic Mechanism of Nuclear Receptor Activation and Its Perturbation in a Human Disease Nature Structural Biology. Feb, 2003 | Pubmed ID: 12536206 The Structural Basis for the Specificity of Retinoid-X Receptor-selective Agonists: New Insights into the Role of Helix H12 The Journal of Biological Chemistry. Mar, 2002 | Pubmed ID: 11782480 소설 및 액세스 접근 : 구조 HEK 293F 서스펜션 세포의 생물학에 대한 재조합 단백질 발현 Nicola Portolano1, Peter J. Watson1, Louise Fairall1, Christopher J. Millard1, Charles P. Milano1, Yun Song1, Shaun M. Cowley1, John W.R. Schwabe1 1Department of Biochemistry, University of Leicester Biology
소설 및 액세스 접근 : 구조 HEK 293F 서스펜션 세포의 생물학에 대한 재조합 단백질 발현 Nicola Portolano1, Peter J. Watson1, Louise Fairall1, Christopher J. Millard1, Charles P. Milano1, Yun Song1, Shaun M. Cowley1, John W.R. Schwabe1 1Department of Biochemistry, University of Leicester Biology