Jong Wook Chang Stem Cell & Regenerative Medicine Institute Samsung Medical Center Biography Publications Institution JoVE Articles Jong Wook Chang has not added a biography. If you are Jong Wook Chang and would like to personalize this page please email our Author Liaison for assistance. Publications Comparative Proteomic Analysis of the Mesenchymal Stem Cells Secretome from Adipose, Bone Marrow, Placenta and Wharton's Jelly International Journal of Molecular Sciences. Jan, 2021 | Pubmed ID: 33467726 Fibulin 5, a Human Wharton's Jelly-derived Mesenchymal Stem Cells-secreted Paracrine Factor, Attenuates Peripheral Nervous System Myelination Defects Through the Integrin-RAC1 Signaling Axis Stem Cells (Dayton, Ohio). Oct, 2020 | Pubmed ID: 33107705 Pressure Stimuli Improve the Proliferation of Wharton's Jelly-Derived Mesenchymal Stem Cells Under Hypoxic Culture Conditions International Journal of Molecular Sciences. Sep, 2020 | Pubmed ID: 32993025 Ethionamide Preconditioning Enhances the Proliferation and Migration of Human Wharton's Jelly-Derived Mesenchymal Stem Cells International Journal of Molecular Sciences. Sep, 2020 | Pubmed ID: 32977637 Anti-Fibrotic Effect of Human Wharton's Jelly-Derived Mesenchymal Stem Cells on Skeletal Muscle Cells, Mediated by Secretion of MMP-1 International Journal of Molecular Sciences. Aug, 2020 | Pubmed ID: 32872523 Exploring the Potential of Mesenchymal Stem Cell-Based Therapy in Mouse Models of Vascular Cognitive Impairment International Journal of Molecular Sciences. Aug, 2020 | Pubmed ID: 32752272 A Comparison of Immune Responses Exerted Following Syngeneic, Allogeneic, and Xenogeneic Transplantation of Mesenchymal Stem Cells into the Mouse Brain International Journal of Molecular Sciences. Apr, 2020 | Pubmed ID: 32357509 Recovery of Tendon Characteristics by Inhibition of Aberrant Differentiation of Tendon-Derived Stem Cells from Degenerative Tendinopathy International Journal of Molecular Sciences. Apr, 2020 | Pubmed ID: 32294907 Loss of HSPA9 Induces Peroxisomal Degradation by Increasing Pexophagy Autophagy. 11, 2020 | Pubmed ID: 31964216 The First Generation of IPSC Line from a Korean Alzheimer's Disease Patient Carrying APP-V715M Mutation Exhibits a Distinct Mitochondrial Dysfunction Experimental Neurobiology. Jun, 2019 | Pubmed ID: 31308793 FGF-17 from Hypoxic Human Wharton's Jelly-Derived Mesenchymal Stem Cells Is Responsible for Maintenance of Cell Proliferation at Late Passages International Journal of Stem Cells. Jul, 2019 | Pubmed ID: 31022995 Cerebrospinal Fluid from Alzheimer's Disease Patients As an Optimal Formulation for Therapeutic Application of Mesenchymal Stem Cells in Alzheimer's Disease Scientific Reports. 01, 2019 | Pubmed ID: 30679696 IPSC Modeling of Presenilin1 Mutation in Alzheimer's Disease with Cerebellar Ataxia Experimental Neurobiology. Oct, 2018 | Pubmed ID: 30429645 Up-regulation of UVRAG by HDAC1 Inhibition Attenuates 5FU-induced Cell Death in HCT116 Colorectal Cancer Cells Anticancer Research. 01, 2018 | Pubmed ID: 29277783 Killing Two Birds with One Stone: The Multifunctional Roles of Mesenchymal Stem Cells in the Treatment of Neurodegenerative and Muscle Diseases Histology and Histopathology. Jul, 2018 | Pubmed ID: 29188600 Optimal Mesenchymal Stem Cell Delivery Routes to Enhance Neurogenesis for the Treatment of Alzheimer's Disease: Optimal MSCs Delivery Routes for the Treatment of AD Histology and Histopathology. Jun, 2018 | Pubmed ID: 29185257 Protein Profiling and Angiogenic Effect of Hypoxia-cultured Human Umbilical Cord Blood-derived Mesenchymal Stem Cells in Hindlimb Ischemia Tissue & Cell. Dec, 2017 | Pubmed ID: 28958480 Lowering the Concentration Affects the Migration and Viability of Intracerebroventricular-delivered Human Mesenchymal Stem Cells Biochemical and Biophysical Research Communications. 11, 2017 | Pubmed ID: 28859977 Effect of Single and Double Administration of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Following Focal Cerebral Ischemia in Rats Experimental Neurobiology. Feb, 2017 | Pubmed ID: 28243167 Agouti Related Peptide Secreted Via Human Mesenchymal Stem Cells Upregulates Proteasome Activity in an Alzheimer's Disease Model Scientific Reports. 01, 2017 | Pubmed ID: 28051110 Magnetic Resonance Imaging of Ferumoxytol-Labeled Human Mesenchymal Stem Cells in the Mouse Brain Stem Cell Reviews and Reports. Feb, 2017 | Pubmed ID: 27757917 Distribution of Human Umbilical Cord Blood-derived Mesenchymal Stem Cells (hUCB-MSCs) in Canines After Intracerebroventricular Injection Neurobiology of Aging. 11, 2016 | Pubmed ID: 27614113 Inhibition of Never in Mitosis A (NIMA)-related Kinase-4 Reduces Survivin Expression and Sensitizes Cancer Cells to TRAIL-induced Cell Death Oncotarget. 10, 2016 | Pubmed ID: 27602754 Activin A Secreted by Human Mesenchymal Stem Cells Induces Neuronal Development and Neurite Outgrowth in an in Vitro Model of Alzheimer's Disease: Neurogenesis Induced by MSCs Via Activin A Archives of Pharmacal Research. Aug, 2016 | Pubmed ID: 27515053 Anti-apoptotic Effects of Human Wharton's Jelly-derived Mesenchymal Stem Cells on Skeletal Muscle Cells Mediated Via Secretion of XCL1 Molecular Therapy : the Journal of the American Society of Gene Therapy. 09, 2016 | Pubmed ID: 27434589 Intra-Arterially Delivered Mesenchymal Stem Cells Are Not Detected in the Brain Parenchyma in an Alzheimer's Disease Mouse Model PloS One. 2016 | Pubmed ID: 27203695 TCTP Regulates Spindle Microtubule Dynamics by Stabilizing Polar Microtubules During Mouse Oocyte Meiosis Biochimica Et Biophysica Acta. Apr, 2016 | Pubmed ID: 26802898 STAT3-survivin Signaling Mediates a Poor Response to Radiotherapy in HER2-positive Breast Cancers Oncotarget. Feb, 2016 | Pubmed ID: 26755645 Distribution of Human Umbilical Cord Blood-derived Mesenchymal Stem Cells in the Alzheimer's Disease Transgenic Mouse After a Single Intravenous Injection Neuroreport. Mar, 2016 | Pubmed ID: 26752148 Proton Irradiation Sensitizes Radioresistant Non-small Cell Lung Cancer Cells by Modulating Epidermal Growth Factor Receptor-mediated DNA Repair Anticancer Research. Jan, 2016 | Pubmed ID: 26722045 Stereotactic Brain Injection of Human Umbilical Cord Blood Mesenchymal Stem Cells in Patients with Alzheimer's Disease Dementia: A Phase 1 Clinical Trial Alzheimer's & Dementia (New York, N. Y.). Sep, 2015 | Pubmed ID: 29854930 The Effect of Donor-Dependent Administration of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Following Focal Cerebral Ischemia in Rats Experimental Neurobiology. Dec, 2015 | Pubmed ID: 26713083 Pexophagy is Induced by Increasing Peroxisomal Reactive Oxygen Species in 1'10-phenanthroline-treated Cells Biochemical and Biophysical Research Communications. Nov, 2015 | Pubmed ID: 26453011 Human Umbilical Cord Blood-derived Mesenchymal Stem Cells Improve Functional Recovery Through Thrombospondin1, Pantraxin3, and Vascular Endothelial Growth Factor in the Ischemic Rat Brain Journal of Neuroscience Research. Dec, 2015 | Pubmed ID: 26332684 GDF-15 Secreted from Human Umbilical Cord Blood Mesenchymal Stem Cells Delivered Through the Cerebrospinal Fluid Promotes Hippocampal Neurogenesis and Synaptic Activity in an Alzheimer's Disease Model Stem Cells and Development. Oct, 2015 | Pubmed ID: 26154268 The Effect of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells in a Collagenase-Induced Intracerebral Hemorrhage Rat Model Experimental Neurobiology. Jun, 2015 | Pubmed ID: 26113794 BIX-01294-induced Autophagy Regulates Elongation of Primary Cilia Biochemical and Biophysical Research Communications. May, 2015 | Pubmed ID: 25796328 Inhibition of Autophagy Suppresses Sertraline-mediated Primary Ciliogenesis in Retinal Pigment Epithelium Cells PloS One. 2015 | Pubmed ID: 25671433 Low Immunogenicity of Allogeneic Human Umbilical Cord Blood-derived Mesenchymal Stem Cells in Vitro and in Vivo Biochemical and Biophysical Research Communications. Apr, 2014 | Pubmed ID: 24657442 Intraspinal Cavity Injection of Human Mesenchymal Stem Cells and Tracking their Migration into the Rat Brain Hyeongseop Kim1,2, Seunghoon Lee3, Jong Wook Chang1,2, A ran Kim4, Hyemin Jang5,6,7, Duk L. Na5,6,7 1Stem Cell & Regenerative Medicine Institute, Samsung Medical Center, 2Stem Cell Institute, ENCell Co. Ltd, 3Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 4Animal Research and Molecular Imaging Center, Samsung Biomedical Research Institute, Samsung Medical Center, 5Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 6Neuroscience Center, Samsung Medical Center, 7Samsung Alzheimer Research Center, Samsung Medical Center JoVE 62120 Biology
Intraspinal Cavity Injection of Human Mesenchymal Stem Cells and Tracking their Migration into the Rat Brain Hyeongseop Kim1,2, Seunghoon Lee3, Jong Wook Chang1,2, A ran Kim4, Hyemin Jang5,6,7, Duk L. Na5,6,7 1Stem Cell & Regenerative Medicine Institute, Samsung Medical Center, 2Stem Cell Institute, ENCell Co. Ltd, 3Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 4Animal Research and Molecular Imaging Center, Samsung Biomedical Research Institute, Samsung Medical Center, 5Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 6Neuroscience Center, Samsung Medical Center, 7Samsung Alzheimer Research Center, Samsung Medical Center JoVE 62120 Biology
