Jordan D. Miller

Publications

• Effects of Altering Mitochondrial Antioxidant Capacity on Molecular and Phenotypic Drivers of Fibrocalcific Aortic Valve Stenosis
  Frontiers in Cardiovascular Medicine. 2021  |   Pubmed ID: 34250048
• MnSOD Protects Against Vascular Calcification Independent of Changes in Vascular Function in Hypercholesterolemic Mice
  Atherosclerosis. Jun, 2021  |   Pubmed ID: 34147244
• Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span
  Annual Review of Pharmacology and Toxicology. 01, 2021  |   Pubmed ID: 32997601
• The Use of Virtual Reality to Reduce Preoperative Anxiety in First-Time Sternotomy Patients: A Randomized Controlled Pilot Trial
  Mayo Clinic Proceedings. 06, 2020  |   Pubmed ID: 32498771
• Influences of Sex and Estrogen in Arterial and Valvular Calcification
  Frontiers in Endocrinology. 2019  |   Pubmed ID: 31620082
• Late-life Time-restricted Feeding and Exercise Differentially Alter Healthspan in Obesity
  Aging Cell. 08, 2019  |   Pubmed ID: 31111669
• Targeting Senescent Cells Alleviates Obesity-induced Metabolic Dysfunction
  Aging Cell. 06, 2019  |   Pubmed ID: 30907060
• Length-independent Telomere Damage Drives Post-mitotic Cardiomyocyte Senescence
  The EMBO Journal. 03, 2019  |   Pubmed ID: 30737259
• Network Tomography for Understanding Phenotypic Presentations in Aortic Stenosis
  JACC. Cardiovascular Imaging. 02, 2019  |   Pubmed ID: 30732719
• Smooth Muscle Brain-derived Neurotrophic Factor Contributes to Airway Hyperreactivity in a Mouse Model of Allergic Asthma
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 02, 2019  |   Pubmed ID: 30351991
• Sirt6 Deficiency Impairs Corneal Epithelial Wound Healing
  Aging. Aug, 2018  |   Pubmed ID: 30070973
• Senolytics Improve Physical Function and Increase Lifespan in Old Age
  Nature Medicine. 08, 2018  |   Pubmed ID: 29988130
• A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD Decline
  Cell Metabolism. May, 2018  |   Pubmed ID: 29719225
• Ca Entry Through Reverse Mode Na/Ca Exchanger Contributes to Store Operated Channel-Mediated Neointima Formation After Arterial Injury
  The Canadian Journal of Cardiology. 06, 2018  |   Pubmed ID: 29705161
• TRPC6 and TRPC4 Heteromultimerization Mediates Store Depletion-Activated NCX1 Reversal in Proliferative Vascular Smooth Muscle Cells
  Channels (Austin, Tex.). 01, 2018  |   Pubmed ID: 29560783
• Pathophysiology of Aortic Valve Stenosis: Is It Both Fibrocalcific and Sex Specific?
  Physiology (Bethesda, Md.). 05, 2017  |   Pubmed ID: 28404735
• Sirt6 Deficiency Results in Progression of Glomerular Injury in the Kidney
  Aging. 03, 2017  |   Pubmed ID: 28351995
• The Impact of Frailty on Patient-Centered Outcomes Following Aortic Valve Replacement
  The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Jul, 2017  |   Pubmed ID: 28329140
• High Fat Diet and Exercise Lead to a Disrupted and Pathogenic DNA Methylome in Mouse Liver
  Epigenetics. Jan, 2017  |   Pubmed ID: 27858497
• 17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization
  The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Jan, 2017  |   Pubmed ID: 26809497
• Cellular Senescence: Implications for Metabolic Disease
  Molecular and Cellular Endocrinology. Aug, 2016  |   Pubmed ID: 27591120
• Frameworks for Proof-of-Concept Clinical Trials of Interventions That Target Fundamental Aging Processes
  The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Nov, 2016  |   Pubmed ID: 27535966
• Left Ventricular Dysfunction After Degenerative Mitral Valve Repair: A Question of Better Molecular Targets or Better Surgical Timing?
  The Journal of Thoracic and Cardiovascular Surgery. Oct, 2016  |   Pubmed ID: 27523402
• Quantification of GDF11 and Myostatin in Human Aging and Cardiovascular Disease
  Cell Metabolism. Jun, 2016  |   Pubmed ID: 27304512
• Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue
  Diabetes. Jun, 2016  |   Pubmed ID: 26983960
• Bidirectional Translation in Cardiovascular Calcification
  Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2016  |   Pubmed ID: 26912744
• Arterial Calcification: Conscripted by Collagen
  Nature Materials. Mar, 2016  |   Pubmed ID: 26906958
• Chronic Senolytic Treatment Alleviates Established Vasomotor Dysfunction in Aged or Atherosclerotic Mice
  Aging Cell. Oct, 2016  |   Pubmed ID: 26864908
• Naturally Occurring P16(Ink4a)-positive Cells Shorten Healthy Lifespan
  Nature. Feb, 2016  |   Pubmed ID: 26840489
• Sex-related Differences in Calcific Aortic Stenosis: Correlating Clinical and Echocardiographic Characteristics and Computed Tomography Aortic Valve Calcium Score to Excised Aortic Valve Weight
  European Heart Journal. Feb, 2016  |   Pubmed ID: 26508159
• Molecular Determinants of Calpain-dependent Cleavage of Junctophilin-2 Protein in Cardiomyocytes
  The Journal of Biological Chemistry. Jul, 2015  |   Pubmed ID: 26063807
• Nonbiased Molecular Screening Identifies Novel Molecular Regulators of Fibrogenic and Proliferative Signaling in Myxomatous Mitral Valve Disease
  Circulation. Cardiovascular Genetics. Jun, 2015  |   Pubmed ID: 25814644
• Reward and Toxicity of Cocaine Metabolites Generated by Cocaine Hydrolase
  Cellular and Molecular Neurobiology. Aug, 2015  |   Pubmed ID: 25814464
• The Achilles' Heel of Senescent Cells: from Transcriptome to Senolytic Drugs
  Aging Cell. Aug, 2015  |   Pubmed ID: 25754370
• Impact of Aortic Valve Calcification, As Measured by MDCT, on Survival in Patients with Aortic Stenosis: Results of an International Registry Study
  Journal of the American College of Cardiology. Sep, 2014  |   Pubmed ID: 25236511
• Microtubule-mediated Defects in Junctophilin-2 Trafficking Contribute to Myocyte Transverse-tubule Remodeling and Ca2+ Handling Dysfunction in Heart Failure
  Circulation. Apr, 2014  |   Pubmed ID: 24519927
• Transcriptional and Phenotypic Changes in Aorta and Aortic Valve with Aging and MnSOD Deficiency in Mice
  American Journal of Physiology. Heart and Circulatory Physiology. Nov, 2013  |   Pubmed ID: 23997094
• Fibrocalcific Aortic Valve Disease: Opportunity to Understand Disease Mechanisms Using Mouse Models
  Circulation Research. Jul, 2013  |   Pubmed ID: 23833295
• TGF-β Signalling and Reactive Oxygen Species Drive Fibrosis and Matrix Remodelling in Myxomatous Mitral Valves
  Cardiovascular Research. Jul, 2013  |   Pubmed ID: 23554457
• Vascular Function During Prolonged Progression and Regression of Atherosclerosis in Mice
  Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2013  |   Pubmed ID: 23307875
• Calcific Aortic Valve Stenosis: Methods, Models, and Mechanisms
  Circulation Research. May, 2011  |   Pubmed ID: 21617136
• Evidence for Active Regulation of Pro-osteogenic Signaling in Advanced Aortic Valve Disease
  Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2010  |   Pubmed ID: 20864669
• MnSOD Protects Against COX1-mediated Endothelial Dysfunction in Chronic Heart Failure
  American Journal of Physiology. Heart and Circulatory Physiology. May, 2010  |   Pubmed ID: 20304815
• Biventricular Adaptation to Volume Overload in Mice with Aortic Regurgitation
  Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance. 2009  |   Pubmed ID: 19671155
• Cardiorespiratory Effects of Inelastic Chest Wall Restriction
  Journal of Applied Physiology (Bethesda, Md. : 1985). Jun, 2002  |   Pubmed ID: 12015356