Jordan J. Green Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Ophthalmology, Oncology, Neurosurgery, Materials Science and Engineering, Chemical and Biomolecular Engineering, and the Bloomberg-Kimmel Institute for Cancer Immunotherapy Johns Hopkins University School of Medicine Biography Publications Institution JoVE Articles Jordan J. Green has not added a biography. If you are Jordan J. Green and would like to personalize this page please email our Author Liaison for assistance. Publications Non-Viral Delivery To Enable Genome Editing Trends in Biotechnology. Sep, 2018 | Pubmed ID: 30278987 Bioreducible Polymeric Nanoparticles Containing Multiplexed Cancer Stem Cell Regulating MiRNAs Inhibit Glioblastoma Growth and Prolong Survival Nano Letters. Jul, 2018 | Pubmed ID: 29927251 Bacterial TRNase-Based Gene Therapy with Poly(β-Amino Ester) Nanoparticles for Suppressing Melanoma Tumor Growth and Relapse Advanced Healthcare Materials. Aug, 2018 | Pubmed ID: 29888531 Injectable Drug Depot Engineered to Release Multiple Ophthalmic Therapeutic Agents with Precise Time Profiles for Postoperative Treatment Following Ocular Surgery Acta Biomaterialia. Jun, 2018 | Pubmed ID: 29684622 Anisotropic Biodegradable Lipid Coated Particles for Spatially Dynamic Protein Presentation Acta Biomaterialia. May, 2018 | Pubmed ID: 29631048 Biodegradable Polymeric Nanoparticles for Therapeutic Cancer Treatments Annual Review of Chemical and Biomolecular Engineering. Jun, 2018 | Pubmed ID: 29579402 Nanoscale Artificial Antigen Presenting Cells for Cancer Immunotherapy Molecular Immunology. Jun, 2018 | Pubmed ID: 29525074 Biomimetic Peptide Display from a Polymeric Nanoparticle Surface for Targeting and Antitumor Activity to Human Triple-negative Breast Cancer Cells Journal of Biomedical Materials Research. Part A. Jun, 2018 | Pubmed ID: 29424479 Biodegradable STING Agonist Nanoparticles for Enhanced Cancer Immunotherapy Nanomedicine : Nanotechnology, Biology, and Medicine. 02, 2018 | Pubmed ID: 29127039 Therapeutic Potential of an Anti-angiogenic Multimodal Biomimetic Peptide in Hepatocellular Carcinoma Oncotarget. Nov, 2017 | Pubmed ID: 29254183 Surface Engineering for Lymphocyte Programming Advanced Drug Delivery Reviews. May, 2017 | Pubmed ID: 28501510 A Triple-Fluorophore-Labeled Nucleic Acid PH Nanosensor to Investigate Non-viral Gene Delivery Molecular Therapy : the Journal of the American Society of Gene Therapy. 07, 2017 | Pubmed ID: 28479046 Polymeric Nanoparticles As Cancer-specific DNA Delivery Vectors to Human Hepatocellular Carcinoma Journal of Controlled Release : Official Journal of the Controlled Release Society. Oct, 2017 | Pubmed ID: 28351668 Nanoparticle Tracking Analysis for Determination of Hydrodynamic Diameter, Concentration, and Zeta-Potential of Polyplex Nanoparticles Methods in Molecular Biology (Clifton, N.J.). 2017 | Pubmed ID: 28238128 Continuous Microfluidic Assembly of Biodegradable Poly(beta-amino Ester)/DNA Nanoparticles for Enhanced Gene Delivery Journal of Biomedical Materials Research. Part A. 06, 2017 | Pubmed ID: 28177587 Tyrosine Kinase Blocking Collagen IV-derived Peptide Suppresses Ocular Neovascularization and Vascular Leakage Science Translational Medicine. 01, 2017 | Pubmed ID: 28100839 Noninvasive Targeted Transcranial Neuromodulation Via Focused Ultrasound Gated Drug Release from Nanoemulsions Nano Letters. 02, 2017 | Pubmed ID: 28094959 Gene Delivery Nanoparticles to Modulate Angiogenesis Advanced Drug Delivery Reviews. Sep, 2017 | Pubmed ID: 27913120 Polymeric Nanoparticle-based Delivery of TRAIL DNA for Cancer-specific Killing Bioengineering & Translational Medicine. Jun, 2016 | Pubmed ID: 28349127 Mimicking Biological Functionality with Polymers for Biomedical Applications Nature. 12, 2016 | Pubmed ID: 27974772 Synthesis and Application of Poly(ethylene Glycol)-co-poly(β-amino Ester) Copolymers for Small Cell Lung Cancer Gene Therapy Acta Biomaterialia. 09, 2016 | Pubmed ID: 27262740 Non-viral Nucleic Acid Containing Nanoparticles As Cancer Therapeutics Expert Opinion on Drug Delivery. Oct, 2016 | Pubmed ID: 27248202 Non-virally Engineered Human Adipose Mesenchymal Stem Cells Produce BMP4, Target Brain Tumors, and Extend Survival Biomaterials. 09, 2016 | Pubmed ID: 27240162 Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours Ecancermedicalscience. 2016 | Pubmed ID: 27110286 Quantification of Cellular and Nuclear Uptake Rates of Polymeric Gene Delivery Nanoparticles and DNA Plasmids Via Flow Cytometry Acta Biomaterialia. 06, 2016 | Pubmed ID: 27019146 Nanoparticle-mediated Transcriptional Modification Enhances Neuronal Differentiation of Human Neural Stem Cells Following Transplantation in Rat Brain Biomaterials. Apr, 2016 | Pubmed ID: 26828681 Layer-by-layer Inorganic/polymeric Nanoparticles for Kinetically Controlled Multigene Delivery Journal of Biomedical Materials Research. Part A. 03, 2016 | Pubmed ID: 26519869 Bioreducible Poly(Beta-Amino Ester)s for Intracellular Delivery of SiRNA Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26472444 Shaping the Future of Nanomedicine: Anisotropy in Polymeric Nanoparticle Design Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. Mar-Apr, 2016 | Pubmed ID: 25981390 Biodegradable Polymer Iron Oxide Nanocomposites: the Future of Biocompatible Magnetism Nanomedicine (London, England). 2015 | Pubmed ID: 26608843 Exploring the Role of Polymer Structure on Intracellular Nucleic Acid Delivery Via Polymeric Nanoparticles Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2015 | Pubmed ID: 26433125 Gene Delivery Polymer Structure-function Relationships Elucidated Via Principal Component Analysis Chemical Communications (Cambridge, England). Aug, 2015 | Pubmed ID: 26126593 Targeted Polymeric Nanoparticles for Cancer Gene Therapy Journal of Drug Targeting. 2015 | Pubmed ID: 26061296 Platelet-Derived Growth Factor BB Enhances Osteogenesis of Adipose-Derived But Not Bone Marrow-Derived Mesenchymal Stromal/Stem Cells Stem Cells (Dayton, Ohio). Sep, 2015 | Pubmed ID: 26013357 Polymeric Nanoparticles for Nonviral Gene Therapy Extend Brain Tumor Survival in Vivo ACS Nano. Feb, 2015 | Pubmed ID: 25643235 An Automated Multidimensional Thin Film Stretching Device for the Generation of Anisotropic Polymeric Micro- and Nanoparticles Journal of Biomedical Materials Research. Part A. Aug, 2015 | Pubmed ID: 25641799 Degradable Polymer-coated Gold Nanoparticles for Co-delivery of DNA and SiRNA Acta Biomaterialia. Jan, 2015 | Pubmed ID: 25246314 Highlights from the Latest Articles in Nanomedicine Nanomedicine (London, England). 05, 2014 | Pubmed ID: 24978461 Hypoxia-inducible Factors and RAB22A Mediate Formation of Microvesicles That Stimulate Breast Cancer Invasion and Metastasis Proceedings of the National Academy of Sciences of the United States of America. Aug, 2014 | Pubmed ID: 24938788 Biodegradable Polymeric Nanoparticles Show High Efficacy and Specificity at DNA Delivery to Human Glioblastoma in Vitro and in Vivo ACS Nano. May, 2014 | Pubmed ID: 24766032 Bioreducible Cationic Polymer-based Nanoparticles for Efficient and Environmentally Triggered Cytoplasmic SiRNA Delivery to Primary Human Brain Cancer Cells ACS Nano. Apr, 2014 | Pubmed ID: 24673565 Differential Polymer Structure Tunes Mechanism of Cellular Uptake and Transfection Routes of Poly(β-amino Ester) Polyplexes in Human Breast Cancer Cells Bioconjugate Chemistry. Jan, 2014 | Pubmed ID: 24320687 Biomolecule Delivery to Engineer the Cellular Microenvironment for Regenerative Medicine Annals of Biomedical Engineering. Jul, 2014 | Pubmed ID: 24170072 Particle Shape Dependence of CD8+ T Cell Activation by Artificial Antigen Presenting Cells Biomaterials. Jan, 2014 | Pubmed ID: 24099710 Evaluating the Potential of Poly(beta-amino Ester) Nanoparticles for Reprogramming Human Fibroblasts to Become Induced Pluripotent Stem Cells International Journal of Nanomedicine. 2013 | Pubmed ID: 24348039 Independent Vs. Cooperative Binding in Polyethylenimine-DNA and Poly(L-lysine)-DNA Polyplexes The Journal of Physical Chemistry. B. Aug, 2013 | Pubmed ID: 23941196 Long-term Suppression of Ocular Neovascularization by Intraocular Injection of Biodegradable Polymeric Particles Containing a Serpin-derived Peptide Biomaterials. Oct, 2013 | Pubmed ID: 23849876 Nanoengineering Approaches to the Design of Artificial Antigen-presenting Cells Nanomedicine (London, England). Jul, 2013 | Pubmed ID: 23837856 Bioengineered Nanoparticles for SiRNA Delivery Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. Sep-Oct, 2013 | Pubmed ID: 23821336 (3-aminopropyl)-4-methylpiperazine End-capped Poly(1,4-butanediol Diacrylate-co-4-amino-1-butanol)-based Multilayer Films for Gene Delivery ACS Applied Materials & Interfaces. Jul, 2013 | Pubmed ID: 23755861 A Bioreducible Linear Poly(β-amino Ester) for SiRNA Delivery Chemical Communications (Cambridge, England). Jun, 2013 | Pubmed ID: 23646347 The Effect and Role of Carbon Atoms in Poly(β-amino Ester)s for DNA Binding and Gene Delivery Journal of the American Chemical Society. May, 2013 | Pubmed ID: 23570657 Student Award Winner in the Ph.D. Category for the 2013 Society for Biomaterials Annual Meeting and Exposition, April 10-13, 2013, Boston, Massachusetts : Biomaterial-mediated Cancer-specific DNA Delivery to Liver Cell Cultures Using Synthetic Poly(beta-amino Ester)s Journal of Biomedical Materials Research. Part A. Jul, 2013 | Pubmed ID: 23559534 Poly(beta-aminoester) Nanoparticle-delivery of P53 Has Activity Against Small Cell Lung Cancer in Vitro and in Vivo Molecular Cancer Therapeutics. Jan, 2013 | Pubmed ID: 23364678 SiRNA Nanomedicine: the Promise of Bioreducible Materials Expert Review of Medical Devices. Jan, 2013 | Pubmed ID: 23278217 Subtle Changes to Polymer Structure and Degradation Mechanism Enable Highly Effective Nanoparticles for SiRNA and DNA Delivery to Human Brain Cancer Advanced Healthcare Materials. Sep, 2012 | Pubmed ID: 23184674 Uptake and Transfection with Polymeric Nanoparticles Are Dependent on Polymer End-group Structure, but Largely Independent of Nanoparticle Physical and Chemical Properties Molecular Pharmaceutics. Nov, 2012 | Pubmed ID: 22970908 Cystamine-terminated Poly(beta-amino Ester)s for SiRNA Delivery to Human Mesenchymal Stem Cells and Enhancement of Osteogenic Differentiation Biomaterials. Nov, 2012 | Pubmed ID: 22871421 Poly(β-amino Ester)-nanoparticle Mediated Transfection of Retinal Pigment Epithelial Cells in Vitro and in Vivo PloS One. 2012 | Pubmed ID: 22629417 2011 Rita Schaffer Lecture: Nanoparticles for Intracellular Nucleic Acid Delivery Annals of Biomedical Engineering. Jul, 2012 | Pubmed ID: 22451256 Therapeutic Angiogenesis Using Genetically Engineered Human Endothelial Cells Journal of Controlled Release : Official Journal of the Controlled Release Society. Jun, 2012 | Pubmed ID: 22450331 Gene Delivery Nanoparticles Specific for Human Microvasculature and Macrovasculature Nanomedicine : Nanotechnology, Biology, and Medicine. Oct, 2012 | Pubmed ID: 22306159 A Novel Assay for Quantifying the Number of Plasmids Encapsulated by Polymer Nanoparticles Small (Weinheim an Der Bergstrasse, Germany). Feb, 2012 | Pubmed ID: 22139973 Advances in Polymeric and Inorganic Vectors for Nonviral Nucleic Acid Delivery Therapeutic Delivery. Apr, 2011 | Pubmed ID: 22826857 Synthetic Poly(ester Amine) and Poly(amido Amine) Nanoparticles for Efficient DNA and SiRNA Delivery to Human Endothelial Cells International Journal of Nanomedicine. 2011 | Pubmed ID: 22228998 Effects of Base Polymer Hydrophobicity and End-group Modification on Polymeric Gene Delivery Biomacromolecules. Oct, 2011 | Pubmed ID: 21888340 Poly(β-amino Ester)-DNA Complexes: Time-resolved Fluorescence and Cellular Transfection Studies Journal of Controlled Release : Official Journal of the Controlled Release Society. Sep, 2011 | Pubmed ID: 21699928 Non-viral Gene Delivery Nanoparticles Based on Poly(β-amino Esters) for Treatment of Glioblastoma Biomaterials. Aug, 2011 | Pubmed ID: 21536325 Drug Delivery Strategies for Therapeutic Angiogenesis and Antiangiogenesis Expert Opinion on Drug Delivery. Apr, 2011 | Pubmed ID: 21338327 The Relationship Between Terminal Functionalization and Molecular Weight of a Gene Delivery Polymer and Transfection Efficacy in Mammary Epithelial 2-D Cultures and 3-D Organotypic Cultures Biomaterials. Nov, 2010 | Pubmed ID: 20674001 Electrostatic Surface Modifications to Improve Gene Delivery Expert Opinion on Drug Delivery. Apr, 2010 | Pubmed ID: 20201712 Tissue-specific Gene Delivery Via Nanoparticle Coating Biomaterials. Feb, 2010 | Pubmed ID: 19850333 Genetic Engineering of Human Stem Cells for Enhanced Angiogenesis Using Biodegradable Polymeric Nanoparticles Proceedings of the National Academy of Sciences of the United States of America. Feb, 2010 | Pubmed ID: 19805054 Small-Molecule End-Groups of Linear Polymer Determine Cell-type Gene-Delivery Efficacy Advanced Materials (Deerfield Beach, Fla.). Dec, 2009 | Pubmed ID: 25165411 Degradable Polymers for Gene Delivery Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2009 | Pubmed ID: 19964958 Nanoparticle-delivered Suicide Gene Therapy Effectively Reduces Ovarian Tumor Burden in Mice Cancer Research. Aug, 2009 | Pubmed ID: 19643734 Gold, Poly(beta-amino Ester) Nanoparticles for Small Interfering RNA Delivery Nano Letters. Jun, 2009 | Pubmed ID: 19422265 Poly(beta-amino Esters): Procedures for Synthesis and Gene Delivery Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19085119 Nanoparticulate Delivery of Diphtheria Toxin DNA Effectively Kills Mesothelin Expressing Pancreatic Cancer Cells Cancer Biology & Therapy. Oct, 2008 | Pubmed ID: 19039293 Nanoparticles for Gene Transfer to Human Embryonic Stem Cell Colonies Nano Letters. Oct, 2008 | Pubmed ID: 18754690 A Combinatorial Polymer Library Approach Yields Insight into Nonviral Gene Delivery Accounts of Chemical Research. May, 2008 | Pubmed ID: 18507402 Electrostatic Ligand Coatings of Nanoparticles Enable Ligand-specific Gene Delivery to Human Primary Cells Nano Letters. Apr, 2007 | Pubmed ID: 17362046 Biodegradable Polymeric Vectors for Gene Delivery to Human Endothelial Cells Bioconjugate Chemistry. Sep-Oct, 2006 | Pubmed ID: 16984124 Fabricação de anisotrópica poliméricas Artificial células apresentadoras para ativação de células T CD8 + Elana Ben-Akiva*1, Kelly R. Rhodes*1, Randall A. Meyer1, Jordan J. Green2 1Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Johns Hopkins University School of Medicine, 2Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Ophthalmology, Oncology, Neurosurgery, Materials Science and Engineering, Chemical and Biomolecular Engineering, and the Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine JoVE 58332 Environment Avaliação de Entrega Gene Polimérico Nanopartículas por Análise Nanoparticle Rastreamento e alta capacidade de Citometria de Fluxo Ron B. Shmueli1,2, Nupura S. Bhise1,2, Jordan J. Green1,2,3,4 1Biomedical Engineering Department, Johns Hopkins University School of Medicine, 2Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, 3Wilmer Eye Institute, Johns Hopkins University School of Medicine, 4Institute for Nanobiotechnology, Johns Hopkins University School of Medicine JoVE 50176 Bioengineering
Fabricação de anisotrópica poliméricas Artificial células apresentadoras para ativação de células T CD8 + Elana Ben-Akiva*1, Kelly R. Rhodes*1, Randall A. Meyer1, Jordan J. Green2 1Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Johns Hopkins University School of Medicine, 2Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Ophthalmology, Oncology, Neurosurgery, Materials Science and Engineering, Chemical and Biomolecular Engineering, and the Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine JoVE 58332 Environment
Avaliação de Entrega Gene Polimérico Nanopartículas por Análise Nanoparticle Rastreamento e alta capacidade de Citometria de Fluxo Ron B. Shmueli1,2, Nupura S. Bhise1,2, Jordan J. Green1,2,3,4 1Biomedical Engineering Department, Johns Hopkins University School of Medicine, 2Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, 3Wilmer Eye Institute, Johns Hopkins University School of Medicine, 4Institute for Nanobiotechnology, Johns Hopkins University School of Medicine JoVE 50176 Bioengineering