Jorge Busciglio Department of Neurobiology and Behavior University of California, Irvine Biography Publications Institution JoVE Articles Jorge Busciglio has not added a biography. If you are Jorge Busciglio and would like to personalize this page please email our Author Liaison for assistance. Publications Mitochondrial Dysfunction and Down's Syndrome: is There a Role for Coenzyme Q(10) ? BioFactors (Oxford, England). Sep, 2011 | Pubmed ID: 22009852 A Role for Thrombospondin-1 Deficits in Astrocyte-mediated Spine and Synaptic Pathology in Down's Syndrome PloS One. 2010 | Pubmed ID: 21152035 A Role for Synaptic Zinc in Activity-dependent Abeta Oligomer Formation and Accumulation at Excitatory Synapses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2009 | Pubmed ID: 19339596 Brain Oxidative Stress in a Triple-transgenic Mouse Model of Alzheimer Disease Free Radical Biology & Medicine. Jun, 2008 | Pubmed ID: 18423383 Tau Isoform Expression and Regulation in Human Cortical Neurons FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2008 | Pubmed ID: 18263702 NAP and ADNF-9 Protect Normal and Down's Syndrome Cortical Neurons from Oxidative Damage and Apoptosis Current Pharmaceutical Design. 2007 | Pubmed ID: 17430172 Beta-amyloid, Oxidative Stress and Down Syndrome Current Alzheimer Research. Dec, 2006 | Pubmed ID: 17168651 Phosphorylation of Actin-depolymerizing Factor/cofilin by LIM-kinase Mediates Amyloid Beta-induced Degeneration: a Potential Mechanism of Neuronal Dystrophy in Alzheimer's Disease The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2006 | Pubmed ID: 16775141 Different Conformations of Amyloid Beta Induce Neurotoxicity by Distinct Mechanisms in Human Cortical Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2006 | Pubmed ID: 16738244 Ets-2 Promotes the Activation of a Mitochondrial Death Pathway in Down's Syndrome Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2005 | Pubmed ID: 15745955 Deposition of Amyloid Fibrils Promotes Cell-surface Accumulation of Amyloid Beta Precursor Protein Neurobiology of Disease. Aug, 2004 | Pubmed ID: 15262274 Live Discussion. From Here to There: AbetaPP As an Axonal Transport Receptor--how Could This Explain Neurodegeneration in AD. 15 July 2002 Journal of Alzheimer's Disease : JAD. Dec, 2003 | Pubmed ID: 14765517 Alzheimer's Presenilin 1 Mutations Impair Kinesin-based Axonal Transport The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2003 | Pubmed ID: 12805290 GVS-111 Prevents Oxidative Damage and Apoptosis in Normal and Down's Syndrome Human Cortical Neurons International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience. May, 2003 | Pubmed ID: 12711349 Aberrant Activation of Focal Adhesion Proteins Mediates Fibrillar Amyloid Beta-induced Neuronal Dystrophy The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2003 | Pubmed ID: 12533609 Fast Axonal Transport Misregulation and Alzheimer's Disease Neuromolecular Medicine. 2002 | Pubmed ID: 12428805 Altered Metabolism of the Amyloid Beta Precursor Protein is Associated with Mitochondrial Dysfunction in Down's Syndrome Neuron. Feb, 2002 | Pubmed ID: 11879646 Cryopreservation of Cortical Tissue Blocks for the Generation of Highly Enriched Neuronal Cultures Ardeshir S. Rahman1, Shaudee Parvinjah1, Michael A. Hanna1, Pablo R. Helguera1, Jorge Busciglio1 1Department of Neurobiology and Behavior, University of California, Irvine JoVE 2384 Neuroscience
Cryopreservation of Cortical Tissue Blocks for the Generation of Highly Enriched Neuronal Cultures Ardeshir S. Rahman1, Shaudee Parvinjah1, Michael A. Hanna1, Pablo R. Helguera1, Jorge Busciglio1 1Department of Neurobiology and Behavior, University of California, Irvine JoVE 2384 Neuroscience
