José-Alain Sahel Department of Genetics - Sorbonne Université, INSERM, CNRS Institut de la Vision Biography Publications Institution JoVE Articles José-Alain Sahel has not added a biography. If you are José-Alain Sahel and would like to personalize this page please email our Author Liaison for assistance. Publications Restoration of MGluR6 Localization Following AAV-Mediated Delivery in a Mouse Model of Congenital Stationary Night Blindness Investigative Ophthalmology & Visual Science. Mar, 2021 | Pubmed ID: 33729473 Reproducing Diabetic Retinopathy Features Using Newly Developed Human Induced-pluripotent Stem Cell-derived Retinal Müller Glial Cells Glia. Mar, 2021 | Pubmed ID: 33683746 βA1-crystallin Regulates Glucose Metabolism and Mitochondrial Function in Mouse Retinal Astrocytes by Modulating PTP1B Activity Communications Biology. Feb, 2021 | Pubmed ID: 33627831 Safety of Intravitreal Gene Therapy for Treatment of Subjects with Leber Hereditary Optic Neuropathy Due to Mutations in the Mitochondrial ND4 Gene: The REVEAL Study BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. Mar, 2021 | Pubmed ID: 33566264 Near-infrared Fundus Autofluorescence Alterations Correlate with Swept-source Optical Coherence Tomography Angiography Findings in Patients with Retinitis Pigmentosa Scientific Reports. Feb, 2021 | Pubmed ID: 33542393 CHM Mutation Spectrum and Disease: An Update at the Time of Human Therapeutic Trials Human Mutation. Feb, 2021 | Pubmed ID: 33538369 Retinal Phenotype of Patients With Isolated Retinal Degeneration Due to CLN3 Pathogenic Variants in a French Retinitis Pigmentosa Cohort JAMA Ophthalmology. Mar, 2021 | Pubmed ID: 33507216 Optogenetic Therapy: High Spatiotemporal Resolution and Pattern Discrimination Compatible with Vision Restoration in Non-human Primates Communications Biology. Jan, 2021 | Pubmed ID: 33504896 A Splice Variant in Gene Leads to Lactate Transport Deficit in Human IPS Cell-Derived Retinal Pigment Epithelial Cells Cells. Jan, 2021 | Pubmed ID: 33477551 Efficacy and Safety of Intravitreal Gene Therapy for Leber Hereditary Optic Neuropathy Treated Within 6 Months of Disease Onset Ophthalmology. Jan, 2021 | Pubmed ID: 33451738 BNIP3L-mediated Mitophagy is Required for Mitochondrial Remodeling During the Differentiation of Optic Nerve Oligodendrocytes Autophagy. Jan, 2021 | Pubmed ID: 33404293 WDR34, a Candidate Gene for Non-syndromic Rod-cone Dystrophy Clinical Genetics. Feb, 2021 | Pubmed ID: 33124039 Quality of Evidence in Ophthalmology: An Overview of Cochrane Reviews Ophthalmology. Feb, 2021 | Pubmed ID: 32652204 Improved Performance and Safety from Argus II Retinal Prosthesis Post-approval Study in France Acta Ophthalmologica. Dec, 2020 | Pubmed ID: 33354943 Bilateral Visual Improvement with Unilateral Gene Therapy Injection for Leber Hereditary Optic Neuropathy Science Translational Medicine. 12, 2020 | Pubmed ID: 33298565 Insulin Inhibits Inflammation-induced Cone Death in Retinal Detachment Journal of Neuroinflammation. Nov, 2020 | Pubmed ID: 33243251 Generation of a Transplantable Population of Human IPSC-Derived Retinal Ganglion Cells Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 33195235 [Vision Restoration: Science Fiction or Reality?] Medecine Sciences : M/S. Nov, 2020 | Pubmed ID: 33151850 Topical Treatment with a Mu Opioid Receptor Agonist Alleviates Corneal Allodynia and Corneal Nerve Sensitization in Mice Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Dec, 2020 | Pubmed ID: 33035833 [On the Inflammatory Origins of AMD] Medecine Sciences : M/S. Oct, 2020 | Pubmed ID: 33026331 Dynamic Full-field Optical Coherence Tomography: 3D Live-imaging of Retinal Organoids Light, Science & Applications. 2020 | Pubmed ID: 32864115 Phototoxic Damage to Cone Photoreceptors Can Be Independent of the Visual Pigment: the Porphyrin Hypothesis Cell Death & Disease. 08, 2020 | Pubmed ID: 32862199 DEEP-PHENOTYPING AND FURTHER INSIGHTS IN ITM2B-RELATED RETINAL DYSTROPHY Retina (Philadelphia, Pa.). Aug, 2020 | Pubmed ID: 32826790 The 10q26 Risk Haplotype of Age-Related Macular Degeneration Aggravates Subretinal Inflammation by Impairing Monocyte Elimination Immunity. Aug, 2020 | Pubmed ID: 32814029 VEGF is an Autocrine/paracrine Neuroprotective Factor for Injured Retinal Ganglion Neurons Scientific Reports. 07, 2020 | Pubmed ID: 32710087 Towards Optogenetic Vision Restoration with High Resolution PLoS Computational Biology. 07, 2020 | Pubmed ID: 32667921 AAV-Mediated Gene Delivery to Foveal Cones Methods in Molecular Biology (Clifton, N.J.). 2020 | Pubmed ID: 32651912 Correlations Between Subjective Evaluation of Quality of Life, Visual Field Loss, and Performance in Simulated Activities of Daily Living in Glaucoma Patients Journal of Glaucoma. 10, 2020 | Pubmed ID: 32649451 Functional Ultrasound Imaging of Deep Visual Cortex in Awake Nonhuman Primates Proceedings of the National Academy of Sciences of the United States of America. 06, 2020 | Pubmed ID: 32513717 Loss of Function of RIMS2 Causes a Syndromic Congenital Cone-Rod Synaptic Disease with Neurodevelopmental and Pancreatic Involvement American Journal of Human Genetics. 06, 2020 | Pubmed ID: 32470375 Baseline Visual Field Findings in the RUSH2A Study: Associated Factors and Correlation With Other Measures of Disease Severity American Journal of Ophthalmology. 11, 2020 | Pubmed ID: 32446738 Impact of the COVID-19 Lockdown on Basic Science Research in Ophthalmology: the Experience of a Highly Specialized Research Facility in France Eye (London, England). Jul, 2020 | Pubmed ID: 32382143 Identification and Characterization of Novel TRPM1 Autoantibodies from Serum of Patients with Melanoma-associated Retinopathy PloS One. 2020 | Pubmed ID: 32324760 Systemic Administration of the Di-apocarotenoid Norbixin (BIO201) is Neuroprotective, Preserves Photoreceptor Function and Inhibits A2E and Lipofuscin Accumulation in Animal Models of Age-related Macular Degeneration and Stargardt Disease Aging. 04, 2020 | Pubmed ID: 32255762 Metabolic and Redox Signaling of the Nucleoredoxin-Like-1 Gene for the Treatment of Genetic Retinal Diseases International Journal of Molecular Sciences. Feb, 2020 | Pubmed ID: 32120883 Progressive Chorioretinal Involvement in a Patient with Light-chain (AL) Amyloidosis: a Case Report BMC Ophthalmology. Feb, 2020 | Pubmed ID: 32085748 AAV-Mediated Gene Delivery to 3D Retinal Organoids Derived from Human Induced Pluripotent Stem Cells International Journal of Molecular Sciences. Feb, 2020 | Pubmed ID: 32028585 Opsins for Vision Restoration Biochemical and Biophysical Research Communications. 06, 2020 | Pubmed ID: 31982136 ATTENUATION OUTER RETINAL BANDS ON OPTICAL COHERENCE TOMOGRAPHY FOLLOWING MACULAR EDEMA: A Possible Manifestation of Photoreceptor Misalignment Retina (Philadelphia, Pa.). Nov, 2020 | Pubmed ID: 31922497 IL-1β Induces Rod Degeneration Through the Disruption of Retinal Glutamate Homeostasis Journal of Neuroinflammation. Jan, 2020 | Pubmed ID: 31900165 Behavioural Responses to a Photovoltaic Subretinal Prosthesis Implanted in Non-human Primates Nature Biomedical Engineering. 02, 2020 | Pubmed ID: 31792423 Clinical-grade Production and Safe Delivery of Human ESC Derived RPE Sheets in Primates and Rodents Biomaterials. 02, 2020 | Pubmed ID: 31732225 Age-related Preference for Geometric Spatial Cues During Real-world Navigation Nature Human Behaviour. 01, 2020 | Pubmed ID: 31548677 Effect of Visual Search Training on Saccades in Age-related Macular Degeneration Subjects Current Aging Science. 2020 | Pubmed ID: 31518228 PHENOTYPIC CHARACTERISTICS OF ROD-CONE DYSTROPHY ASSOCIATED WITH MYO7A MUTATIONS IN A LARGE FRENCH COHORT Retina (Philadelphia, Pa.). Aug, 2020 | Pubmed ID: 31479088 CD36 Deficiency Inhibits Retinal Inflammation and Retinal Degeneration in Knockout Mice Frontiers in Immunology. 2019 | Pubmed ID: 31969887 The Primate Model for Understanding and Restoring Vision Proceedings of the National Academy of Sciences of the United States of America. Dec, 2019 | Pubmed ID: 31871177 Implications of Monocular Vision for Racing Drivers PloS One. 2019 | Pubmed ID: 31841526 Peripapillary Sparing With Near Infrared Autofluorescence Correlates With Electroretinographic Findings in Patients With Stargardt Disease Investigative Ophthalmology & Visual Science. 12, 2019 | Pubmed ID: 31790517 Generation of Human Induced Pluripotent Stem Cell Lines from a Patient with ITM2B-related Retinal Dystrophy and a Non Mutated Brother Stem Cell Research. 12, 2019 | Pubmed ID: 31731182 Ocular Injuries Caused by Less-lethal Weapons in France Lancet (London, England). 11, 2019 | Pubmed ID: 31690443 Waveform Analysis of Human Retinal and Choroidal Blood Flow with Laser Doppler Holography Biomedical Optics Express. Oct, 2019 | Pubmed ID: 31646021 Prevalence of Deep-Intronic Variants and Related Phenotype in An Unsolved "One-Hit" Cohort with Stargardt Disease International Journal of Molecular Sciences. Oct, 2019 | Pubmed ID: 31614660 Restoration of Visual Function by Transplantation of Optogenetically Engineered Photoreceptors Nature Communications. 10, 2019 | Pubmed ID: 31586094 Phenotype Analysis of Retinal Dystrophies in Light of the Underlying Genetic Defects: Application to Cone and Cone-Rod Dystrophies International Journal of Molecular Sciences. Sep, 2019 | Pubmed ID: 31574917 Outer Retinal Alterations Associated With Visual Outcomes in Best Vitelliform Macular Dystrophy American Journal of Ophthalmology. 12, 2019 | Pubmed ID: 31465755 Progression of Stargardt Disease As Determined by Fundus Autofluorescence Over a 12-Month Period: ProgStar Report No. 11 JAMA Ophthalmology. Aug, 2019 | Pubmed ID: 31369039 Mo-derived Perivascular Macrophage Recruitment Protects Against Endothelial Cell Death in Retinal Vein Occlusion Journal of Neuroinflammation. Jul, 2019 | Pubmed ID: 31351497 Full-field Electroretinography, Visual Acuity and Visual Fields in Usher Syndrome: a Multicentre European Study Documenta Ophthalmologica. Advances in Ophthalmology. 10, 2019 | Pubmed ID: 31267413 Carotenoid Composition and Conformation in Retinal Oil Droplets of the Domestic Chicken PloS One. 2019 | Pubmed ID: 31150434 Depicting Brighter Possibilities for Treating Blindness Science Translational Medicine. 05, 2019 | Pubmed ID: 31142676 Identification of a Novel GRM6 Mutation in a Previously Described Consanguineous Family with Complete Congenital Stationary Night Blindness Ophthalmic Genetics. 04, 2019 | Pubmed ID: 31063016 Longitudinal Clinical Follow-up and Genetic Spectrum of Patients With Rod-Cone Dystrophy Associated With Mutations in PDE6A and PDE6B JAMA Ophthalmology. 06, 2019 | Pubmed ID: 30998820 Functional Ultrasound Imaging of the Brain Reveals Propagation of Task-related Brain Activity in Behaving Primates Nature Communications. 03, 2019 | Pubmed ID: 30923310 A Mathematical Analysis of Aerobic Glycolysis Triggered by Glucose Uptake in Cones Scientific Reports. 03, 2019 | Pubmed ID: 30858444 Where Are the Missing Gene Defects in Inherited Retinal Disorders? Intronic and Synonymous Variants Contribute at Least to 4% of CACNA1F-mediated Inherited Retinal Disorders Human Mutation. 06, 2019 | Pubmed ID: 30825406 Choroidal Vasculature Imaging with Laser Doppler Holography Biomedical Optics Express. Feb, 2019 | Pubmed ID: 30800528 The Development of White Matter Structural Changes During the Process of Deterioration of the Visual Field Scientific Reports. 02, 2019 | Pubmed ID: 30765782 Immune Response and Intraocular Inflammation in Patients With Leber Hereditary Optic Neuropathy Treated With Intravitreal Injection of Recombinant Adeno-Associated Virus 2 Carrying the ND4 Gene: A Secondary Analysis of a Phase 1/2 Clinical Trial JAMA Ophthalmology. 04, 2019 | Pubmed ID: 30730541 Gene Therapy for Retinal Dystrophy Nature Medicine. 02, 2019 | Pubmed ID: 30718907 Effects of Corneal Injury on Ciliary Nerve Fibre Activity and Corneal Nociception in Mice: A Behavioural and Electrophysiological Study European Journal of Pain (London, England). 03, 2019 | Pubmed ID: 30370980 Whole Exome Sequencing Resolves Complex Phenotype and Identifies CC2D2A Mutations Underlying Non-syndromic Rod-cone Dystrophy Clinical Genetics. 02, 2019 | Pubmed ID: 30267408 Scotopic Microperimetric Assessment of Rod Function in Stargardt Disease (SMART) Study: Design and Baseline Characteristics (Report No. 1) Ophthalmic Research. 2019 | Pubmed ID: 29940588 AUTOSOMAL DOMINANT VITREORETINOCHOROIDOPATHY: When Molecular Genetic Testing Helps Clinical Diagnosis Retina (Philadelphia, Pa.). May, 2019 | Pubmed ID: 29370033 Adapted Surgical Procedure for Argus II Retinal Implantation: Feasibility, Safety, Efficiency, and Postoperative Anatomic Findings Ophthalmology. Retina. 04, 2018 | Pubmed ID: 31047236 Optogenetic Light Sensors in Human Retinal Organoids Frontiers in Neuroscience. 2018 | Pubmed ID: 30450028 Translational Retinal Research and Therapies Translational Vision Science & Technology. Sep, 2018 | Pubmed ID: 30225158 Correlation Between Visual Function and Performance of Simulated Daily Living Activities in Glaucomatous Patients Journal of Glaucoma. 11, 2018 | Pubmed ID: 30157061 Characterization and Transplantation of CD73-Positive Photoreceptors Isolated from Human IPSC-Derived Retinal Organoids Stem Cell Reports. Jul, 2018 | Pubmed ID: 30100409 Expanding the Mutation Spectrum in : Sixty Novel Disease Causing Variants and Their Associated Phenotype in a Large French Stargardt Cohort International Journal of Molecular Sciences. Jul, 2018 | Pubmed ID: 30060493 Visual Brain Plasticity Induced by Central and Peripheral Visual Field Loss Brain Structure & Function. Sep, 2018 | Pubmed ID: 29936553 Restoring Vision Nature. May, 2018 | Pubmed ID: 29769667 Phenotypic Characteristics of a French Cohort of Patients with X-Linked Retinoschisis Ophthalmology. 10, 2018 | Pubmed ID: 29739629 Maintaining Cone Function in Rod-Cone Dystrophies Advances in Experimental Medicine and Biology. 2018 | Pubmed ID: 29721982 Dietary, Environmental, and Genetic Risk Factors of Extensive Macular Atrophy with Pseudodrusen, a Severe Bilateral Macular Atrophy of Middle-aged Patients Scientific Reports. 05, 2018 | Pubmed ID: 29717154 MERTK Mutation Update in Inherited Retinal Diseases Human Mutation. 07, 2018 | Pubmed ID: 29659094 Multimodal Imaging Including Semiquantitative Short-wavelength and Near-infrared Autofluorescence in Achromatopsia Scientific Reports. 04, 2018 | Pubmed ID: 29618791 Chronic Exposure to Tumor Necrosis Factor Alpha Induces Retinal Pigment Epithelium Cell Dedifferentiation Journal of Neuroinflammation. Mar, 2018 | Pubmed ID: 29548329 Light Action Spectrum on Oxidative Stress and Mitochondrial Damage in A2E-loaded Retinal Pigment Epithelium Cells Cell Death & Disease. 02, 2018 | Pubmed ID: 29459695 Safety of RAAV2/2-ND4 Gene Therapy for Leber Hereditary Optic Neuropathy Ophthalmology. 06, 2018 | Pubmed ID: 29426586 Noninvasive Gene Delivery to Foveal Cones for Vision Restoration JCI Insight. 01, 2018 | Pubmed ID: 29367457 Otx2-Genetically Modified Retinal Pigment Epithelial Cells Rescue Photoreceptors After Transplantation Molecular Therapy : the Journal of the American Society of Gene Therapy. 01, 2018 | Pubmed ID: 28988713 [Age-related Macular Degeneration Diagnosis] La Revue Du Praticien. 01, 2017 | Pubmed ID: 30512446 [Age-related Macular Degeneration] La Revue Du Praticien. 01, 2017 | Pubmed ID: 30512444 Human ESC-derived Retinal Epithelial Cell Sheets Potentiate Rescue of Photoreceptor Cell Loss in Rats with Retinal Degeneration Science Translational Medicine. Dec, 2017 | Pubmed ID: 29263231 Further Insights into the Ciliary Gene and Protein KIZ and Its Murine Ortholog PLK1S1 Mutated in Rod-Cone Dystrophy Genes. Oct, 2017 | Pubmed ID: 29057815 Establishment of an Induced Pluripotent Stem (iPS) Cell Line from Dermal Fibroblasts of an Asymptomatic Patient with Dominant PRPF31 Mutation Stem Cell Research. Dec, 2017 | Pubmed ID: 29040912 Generation of an Induced Pluripotent Stem Cell (iPSC) Line from a Patient with Autosomal Dominant Retinitis Pigmentosa Due to a Mutation in the NR2E3 Gene Stem Cell Research. 10, 2017 | Pubmed ID: 29034877 Taurine Promotes Retinal Ganglion Cell Survival Through GABA Receptor Activation Advances in Experimental Medicine and Biology. 2017 | Pubmed ID: 28849492 A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina Molecular Therapy : the Journal of the American Society of Gene Therapy. Nov, 2017 | Pubmed ID: 28807567 Adaptive Gaze Strategies for Locomotion with Constricted Visual Field Frontiers in Human Neuroscience. 2017 | Pubmed ID: 28798674 On Phagocytes and Macular Degeneration Progress in Retinal and Eye Research. Nov, 2017 | Pubmed ID: 28602950 Usher Syndrome Type 1-associated Cadherins Shape the Photoreceptor Outer Segment The Journal of Cell Biology. 06, 2017 | Pubmed ID: 28495838 Novel Splice-site Mutation in TTLL5 Causes Cone Dystrophy in a Consanguineous Family Molecular Vision. 2017 | Pubmed ID: 28356705 LRIT3 Differentially Affects Connectivity and Synaptic Transmission of Cones to ON- and OFF-Bipolar Cells Investigative Ophthalmology & Visual Science. Mar, 2017 | Pubmed ID: 28334377 Impact of Retinitis Pigmentosa on Quality of Life, Mental Health, and Employment Among Young Adults American Journal of Ophthalmology. May, 2017 | Pubmed ID: 28237413 Reorganization of Early Visual Cortex Functional Connectivity Following Selective Peripheral and Central Visual Loss Scientific Reports. 02, 2017 | Pubmed ID: 28233790 Complement Factor H Inhibits CD47-Mediated Resolution of Inflammation Immunity. 02, 2017 | Pubmed ID: 28228282 Generation of Storable Retinal Organoids and Retinal Pigmented Epithelium from Adherent Human IPS Cells in Xeno-Free and Feeder-Free Conditions Stem Cells (Dayton, Ohio). 05, 2017 | Pubmed ID: 28220575 3D Functional Ultrasound Imaging of the Cerebral Visual System in Rodents NeuroImage. 04, 2017 | Pubmed ID: 28167348 Col4a1 Mutation Generates Vascular Abnormalities Correlated with Neuronal Damage in a Mouse Model of HANAC Syndrome Neurobiology of Disease. Apr, 2017 | Pubmed ID: 28057519 Lebecetin, a C-type Lectin, Inhibits Choroidal and Retinal Neovascularization FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 03, 2017 | Pubmed ID: 27974593 Activated Monocytes Resist Elimination by Retinal Pigment Epithelium and Downregulate Their OTX2 Expression Via TNF-α Aging Cell. Feb, 2017 | Pubmed ID: 27660103 Metabolic and Redox Signaling in the Retina Cellular and Molecular Life Sciences : CMLS. 10, 2017 | Pubmed ID: 27543457 Norbixin Protects Retinal Pigmented Epithelium Cells and Photoreceptors Against A2E-Mediated Phototoxicity In Vitro and In Vivo PloS One. 2016 | Pubmed ID: 27992460 Identification of a Novel Homozygous Nonsense Mutation Confirms the Implication of GNAT1 in Rod-Cone Dystrophy PloS One. 2016 | Pubmed ID: 27977773 Emerging Therapies for Inherited Retinal Degeneration Science Translational Medicine. 12, 2016 | Pubmed ID: 27928030 Quantitative and Topographical Analysis of the Losses of Cone Photoreceptors and Retinal Ganglion Cells Under Taurine Depletion Investigative Ophthalmology & Visual Science. 09, 2016 | Pubmed ID: 27607415 A New Autosomal Dominant Eye and Lung Syndrome Linked to Mutations in TIMP3 Gene Scientific Reports. Sep, 2016 | Pubmed ID: 27601084 Argus II Retinal Prosthesis Implantation with Scleral Flap and Autogenous Temporalis Fascia As Alternative Patch Graft Material: a 4-year Follow-up Clinical Ophthalmology (Auckland, N.Z.). 2016 | Pubmed ID: 27574397 Martinique Crinkled Retinal Pigment Epitheliopathy: Clinical Stages and Pathophysiologic Insights Ophthalmology. Oct, 2016 | Pubmed ID: 27474146 An Innovative Strategy for the Molecular Diagnosis of Usher Syndrome Identifies Causal Biallelic Mutations in 93% of European Patients European Journal of Human Genetics : EJHG. 12, 2016 | Pubmed ID: 27460420 Five-Year Safety and Performance Results from the Argus II Retinal Prosthesis System Clinical Trial Ophthalmology. 10, 2016 | Pubmed ID: 27453256 Mathematical Model of the Role of RdCVF in the Coexistence of Rods and Cones in a Healthy Eye Bulletin of Mathematical Biology. 07, 2016 | Pubmed ID: 27444436 Subretinal Mononuclear Phagocytes Induce Cone Segment Loss Via IL-1β ELife. 07, 2016 | Pubmed ID: 27438413 Visual Acuity Loss and Associated Risk Factors in the Retrospective Progression of Stargardt Disease Study (ProgStar Report No. 2) Ophthalmology. 09, 2016 | Pubmed ID: 27378015 Clinical Characteristics and Risk Factors of Extensive Macular Atrophy with Pseudodrusen: The EMAP Case-Control National Clinical Trial Ophthalmology. Sep, 2016 | Pubmed ID: 27320518 AAV-mediated Gene Therapy in Dystrophin-Dp71 Deficient Mouse Leads to Blood-retinal Barrier Restoration and Oedema Reabsorption Human Molecular Genetics. 07, 2016 | Pubmed ID: 27288449 Insight into the Mechanisms of Enhanced Retinal Transduction by the Engineered AAV2 Capsid Variant -7m8 Biotechnology and Bioengineering. 12, 2016 | Pubmed ID: 27259396 Increased Functional Connectivity Between Language and Visually Deprived Areas in Late and Partial Blindness NeuroImage. Aug, 2016 | Pubmed ID: 27143090 Biallelic Mutations in GNB3 Cause a Unique Form of Autosomal-Recessive Congenital Stationary Night Blindness American Journal of Human Genetics. May, 2016 | Pubmed ID: 27063057 The Thioredoxin Encoded by the Rod-Derived Cone Viability Factor Gene Protects Cone Photoreceptors Against Oxidative Stress Antioxidants & Redox Signaling. 06, 2016 | Pubmed ID: 27025156 Identification of an Alternative Splicing Product of the Otx2 Gene Expressed in the Neural Retina and Retinal Pigmented Epithelial Cells PloS One. 2016 | Pubmed ID: 26985665 Run of Homozygosity Analysis Reveals a Novel Nonsense Variant of the CNGB1 Gene Involved in Retinitis Pigmentosa 45 Ophthalmic Genetics. 09, 2016 | Pubmed ID: 26901671 The Natural History of the Progression of Atrophy Secondary to Stargardt Disease (ProgStar) Studies: Design and Baseline Characteristics: ProgStar Report No. 1 Ophthalmology. Apr, 2016 | Pubmed ID: 26786511 Let There Be Light: Gene and Cell Therapy for Blindness Human Gene Therapy. Feb, 2016 | Pubmed ID: 26751519 Ocular Inflammation Induces Trigeminal Pain, Peripheral and Central Neuroinflammatory Mechanisms Neurobiology of Disease. Apr, 2016 | Pubmed ID: 26747211 Altered Astrocyte Morphology and Vascular Development in Dystrophin-Dp71-null Mice Glia. May, 2016 | Pubmed ID: 26711882 A Large Genome-wide Association Study of Age-related Macular Degeneration Highlights Contributions of Rare and Common Variants Nature Genetics. Feb, 2016 | Pubmed ID: 26691988 Functional and High-resolution Retinal Imaging Monitoring Photoreceptor Damage in Acute Macular Neuroretinopathy Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. May, 2016 | Pubmed ID: 26344727 Novel Grading System for Quantification of Cystic Macular Lesions in Usher Syndrome Orphanet Journal of Rare Diseases. Dec, 2015 | Pubmed ID: 26654877 [Altruism in the Retina: Sticks Feed Cones] Medecine Sciences : M/S. Oct, 2015 | Pubmed ID: 26481018 APOE Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2015 | Pubmed ID: 26446211 Intraocular Pressure Reduction and Neuroprotection Conferred by Bone Marrow-derived Mesenchymal Stem Cells in an Animal Model of Glaucoma Stem Cell Research & Therapy. Sep, 2015 | Pubmed ID: 26377305 Structure and Conformation of the Carotenoids in Human Retinal Macular Pigment PloS One. 2015 | Pubmed ID: 26313550 Synthetic 3D Diamond-based Electrodes for Flexible Retinal Neuroprostheses: Model, Production and In vivo Biocompatibility Biomaterials. Oct, 2015 | Pubmed ID: 26210174 Experimental Branch Retinal Vein Occlusion Induces Upstream Pericyte Loss and Vascular Destabilization PloS One. 2015 | Pubmed ID: 26208283 Long-Term Results from an Epiretinal Prosthesis to Restore Sight to the Blind Ophthalmology. Aug, 2015 | Pubmed ID: 26162233 Foxg1-Cre Mediated Lrp2 Inactivation in the Developing Mouse Neural Retina, Ciliary and Retinal Pigment Epithelia Models Congenital High Myopia PloS One. 2015 | Pubmed ID: 26107939 Next-generation Sequencing Applied to a Large French Cone and Cone-rod Dystrophy Cohort: Mutation Spectrum and New Genotype-phenotype Correlation Orphanet Journal of Rare Diseases. Jun, 2015 | Pubmed ID: 26103963 Combined 3DISCO Clearing Method, Retrograde Tracer and Ultramicroscopy to Map Corneal Neurons in a Whole Adult Mouse Trigeminal Ganglion Experimental Eye Research. Oct, 2015 | Pubmed ID: 26072022 Genotypic and Phenotypic Characterization of P23H Line 1 Rat Model PloS One. 2015 | Pubmed ID: 26009893 LRIT3 is Essential to Localize TRPM1 to the Dendritic Tips of Depolarizing Bipolar Cells and May Play a Role in Cone Synapse Formation The European Journal of Neuroscience. Aug, 2015 | Pubmed ID: 25997951 Rod-derived Cone Viability Factor Promotes Cone Survival by Stimulating Aerobic Glycolysis Cell. May, 2015 | Pubmed ID: 25957687 Upregulation of P2RX7 in Cx3cr1-Deficient Mononuclear Phagocytes Leads to Increased Interleukin-1β Secretion and Photoreceptor Neurodegeneration The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2015 | Pubmed ID: 25948251 Dystrophin Dp71 Gene Deletion Induces Retinal Vascular Inflammation and Capillary Degeneration Human Molecular Genetics. Jul, 2015 | Pubmed ID: 25901007 Sildenafil Acutely Decreases Visual Responses in ON and OFF Retinal Ganglion Cells Investigative Ophthalmology & Visual Science. Mar, 2015 | Pubmed ID: 25814000 Optogenetics Current Opinion in Ophthalmology. May, 2015 | Pubmed ID: 25759964 Targeted Next Generation Sequencing Identifies Novel Mutations in RP1 As a Relatively Common Cause of Autosomal Recessive Rod-cone Dystrophy BioMed Research International. 2015 | Pubmed ID: 25692139 Repair of Rhodopsin MRNA by Spliceosome-Mediated RNA Trans-Splicing: A New Approach for Autosomal Dominant Retinitis Pigmentosa Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2015 | Pubmed ID: 25619725 Late Posterior Segment Relapses in a Series of Vogt-Koyanagi-Harada Disease Acta Ophthalmologica. Jan, 2015 | Pubmed ID: 25604241 Apolipoprotein E Promotes Subretinal Mononuclear Phagocyte Survival and Chronic Inflammation in Age-related Macular Degeneration EMBO Molecular Medicine. 2015 | Pubmed ID: 25604058 Gene Therapy for the Eye Focus on Mutation-independent Approaches Current Opinion in Neurology. Feb, 2015 | Pubmed ID: 25545056 Cleavage of Mer Tyrosine Kinase (MerTK) from the Cell Surface Contributes to the Regulation of Retinal Phagocytosis The Journal of Biological Chemistry. Feb, 2015 | Pubmed ID: 25538233 High Prevalence of PRPH2 in Autosomal Dominant Retinitis Pigmentosa in France and Characterization of Biochemical and Clinical Features American Journal of Ophthalmology. Feb, 2015 | Pubmed ID: 25447119 Viral-mediated RdCVF and RdCVFL Expression Protects Cone and Rod Photoreceptors in Retinal Degeneration The Journal of Clinical Investigation. Jan, 2015 | Pubmed ID: 25415434 Clinical Characteristics and Current Therapies for Inherited Retinal Degenerations Cold Spring Harbor Perspectives in Medicine. Feb, 2015 | Pubmed ID: 25324231 Mutations in IFT172 Cause Isolated Retinal Degeneration and Bardet-Biedl Syndrome Human Molecular Genetics. Jan, 2015 | Pubmed ID: 25168386 Targeting Channelrhodopsin-2 to ON-bipolar Cells with Vitreally Administered AAV Restores ON and OFF Visual Responses in Blind Mice Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2015 | Pubmed ID: 25095892 Lack of Dystrophin Protein Dp71 Results in Progressive Cataract Formation Due to Loss of Fiber Cell Organization Molecular Vision. 2014 | Pubmed ID: 25489223 Ocular Tuberculosis: Experience of an Italian and French Cohort Acta Ophthalmologica. Dec, 2014 | Pubmed ID: 25488026 Importance of Eye Position on Spatial Localization in Blind Subjects Wearing an Argus II Retinal Prosthesis Investigative Ophthalmology & Visual Science. Dec, 2014 | Pubmed ID: 25414187 Determination of Morphological, Biometric and Biochemical Susceptibilities in Healthy Eurasier Dogs with Suspected Inherited Glaucoma PloS One. 2014 | Pubmed ID: 25380252 Rods in Daylight Act As Relay Cells for Cone-driven Horizontal Cell-mediated Surround Inhibition Nature Neuroscience. Dec, 2014 | Pubmed ID: 25344628 [Production of in Vitro Retina from Pluripotent Human Stem Cells: a New Therapeutic Tool] Médecine Sciences : M/S. Oct, 2014 | Pubmed ID: 25311017 "En Face" Optical Coherence Tomography Imaging in Type 2 Idiopathic Macular Telangiectasia Retina (Philadelphia, Pa.). Oct, 2014 | Pubmed ID: 25255245 A Neurological Disorder Presumably Underlies Painter Francis Bacon Distorted World Depiction Frontiers in Human Neuroscience. 2014 | Pubmed ID: 25221491 From Confluent Human IPS Cells to Self-forming Neural Retina and Retinal Pigmented Epithelium Proceedings of the National Academy of Sciences of the United States of America. Jun, 2014 | Pubmed ID: 24912154 "En-face" Spectral-domain Optical Coherence Tomography Findings in Multiple Evanescent White Dot Syndrome Journal of Ophthalmology. 2014 | Pubmed ID: 24864197 Spectral-domain Optical Coherence Tomography of the Rodent Eye: Highlighting Layers of the Outer Retina Using Signal Averaging and Comparison with Histology PloS One. 2014 | Pubmed ID: 24788712 Reply: To PMID 23591533 Retina (Philadelphia, Pa.). May, 2014 | Pubmed ID: 24751952 The Cost-effectiveness of the Argus II Retinal Prosthesis in Retinitis Pigmentosa Patients BMC Ophthalmology. 2014 | Pubmed ID: 24731533 Taurine: the Comeback of a Neutraceutical in the Prevention of Retinal Degenerations Progress in Retinal and Eye Research. Jul, 2014 | Pubmed ID: 24721186 Retinal Prostheses: Clinical Results and Future Challenges Comptes Rendus Biologies. Mar, 2014 | Pubmed ID: 24702848 Therapeutic Strategy for Handling Inherited Retinal Degenerations in a Gene-independent Manner Using Rod-derived Cone Viability Factors Comptes Rendus Biologies. Mar, 2014 | Pubmed ID: 24702847 Gene Therapy for Mitochondrial Diseases: Leber Hereditary Optic Neuropathy As the First Candidate for a Clinical Trial Comptes Rendus Biologies. Mar, 2014 | Pubmed ID: 24702846 Gene Therapy for Inherited Retinal Degenerations Comptes Rendus Biologies. Mar, 2014 | Pubmed ID: 24702845 Spotlight on Vision Comptes Rendus Biologies. Mar, 2014 | Pubmed ID: 24702840 Microcystic Changes in the Retinal Internal Nuclear Layer Associated with Optic Atrophy: a Prospective Study Journal of Ophthalmology. 2014 | Pubmed ID: 24701345 Cell Specific Electrodes for Neuronal Network Reconstruction and Monitoring The Analyst. Jul, 2014 | Pubmed ID: 24699623 Whole-exome Sequencing Identifies KIZ As a Ciliary Gene Associated with Autosomal-recessive Rod-cone Dystrophy American Journal of Human Genetics. Apr, 2014 | Pubmed ID: 24680887 Distinctive Glial and Neuronal Interfacing on Nanocrystalline Diamond PloS One. 2014 | Pubmed ID: 24664111 Increased Optic Nerve Radiosensitivity Following Optic Neuritis Neurology. Apr, 2014 | Pubmed ID: 24658931 Neuroglobin Gene Therapy Prevents Optic Atrophy and Preserves Durably Visual Function in Harlequin Mice Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2014 | Pubmed ID: 24622090 Lrit3 Deficient Mouse (nob6): a Novel Model of Complete Congenital Stationary Night Blindness (cCSNB) PloS One. 2014 | Pubmed ID: 24598786 Retinal Vasculitis Imaging by Adaptive Optics Ophthalmology. Jun, 2014 | Pubmed ID: 24576889 Involvement of Bcl-2-associated Transcription Factor 1 in the Differentiation of Early-born Retinal Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2014 | Pubmed ID: 24453340 Morphometric Analysis of Small Arteries in the Human Retina Using Adaptive Optics Imaging: Relationship with Blood Pressure and Focal Vascular Changes Journal of Hypertension. Apr, 2014 | Pubmed ID: 24406779 AAV-mediated Gene Delivery in Dp71-null Mouse Model with Compromised Barriers Glia. Mar, 2014 | Pubmed ID: 24382652 Toward Postnatal Reversal of Ocular Congenital Malformations The Journal of Clinical Investigation. Jan, 2014 | Pubmed ID: 24355915 Functional and High Resolution Retinal Imaging Assessment in a Case of Ocular Siderosis Documenta Ophthalmologica. Advances in Ophthalmology. Feb, 2014 | Pubmed ID: 24337723 The Familial Dementia Gene Revisited: a Missense Mutation Revealed by Whole-exome Sequencing Identifies ITM2B As a Candidate Gene Underlying a Novel Autosomal Dominant Retinal Dystrophy in a Large Family Human Molecular Genetics. Jan, 2014 | Pubmed ID: 24026677 Neonatal Hyperglycemia Inhibits Angiogenesis and Induces Inflammation and Neuronal Degeneration in the Retina PloS One. 2013 | Pubmed ID: 24278148 Further Insights into GPR179: Expression, Localization, and Associated Pathogenic Mechanisms Leading to Complete Congenital Stationary Night Blindness Investigative Ophthalmology & Visual Science. Dec, 2013 | Pubmed ID: 24222301 CCR2(+) Monocytes Infiltrate Atrophic Lesions in Age-related Macular Disease and Mediate Photoreceptor Degeneration in Experimental Subretinal Inflammation in Cx3cr1 Deficient Mice EMBO Molecular Medicine. Nov, 2013 | Pubmed ID: 24142887 [Restoring Vision in Blind Patients Following Photoreceptor Degeneration: Clinical Results and Future Challenges] Biologie Aujourd'hui. 2013 | Pubmed ID: 24103342 [Retinitis Pigmentosa: Eye Sight Restoration by Optogenetic Therapy] Biologie Aujourd'hui. 2013 | Pubmed ID: 24103341 Phototoxic Action Spectrum on a Retinal Pigment Epithelium Model of Age-related Macular Degeneration Exposed to Sunlight Normalized Conditions PloS One. 2013 | Pubmed ID: 24058402 Mutations in IMPG1 Cause Vitelliform Macular Dystrophies American Journal of Human Genetics. Sep, 2013 | Pubmed ID: 23993198 Disease-causing Mutations in BEST1 Gene Are Associated with Altered Sorting of Bestrophin-1 Protein International Journal of Molecular Sciences. 2013 | Pubmed ID: 23880862 Outer Retinal Tubulations in Serpinginous Choroiditis Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Nov, 2013 | Pubmed ID: 23839703 Retinal and Choroidal Changes Observed with 'En Face' Enhanced-depth Imaging OCT in Central Serous Chorioretinopathy The British Journal of Ophthalmology. Sep, 2013 | Pubmed ID: 23823080 Genetic Association Study of Mitochondrial Polymorphisms in Neovascular Age-related Macular Degeneration Molecular Vision. 2013 | Pubmed ID: 23734082 Gene Therapy for Blindness Annual Review of Neuroscience. Jul, 2013 | Pubmed ID: 23724995 Retinal Inner Nuclear Layer Microcystic Changes in Optic Nerve Atrophy: a Novel Spectral-domain OCT Finding Retina (Philadelphia, Pa.). Nov-Dec, 2013 | Pubmed ID: 23644558 Neuroglobin Involvement in Visual Pathways Through the Optic Nerve Biochimica Et Biophysica Acta. Sep, 2013 | Pubmed ID: 23639750 Adaptive Optics Imaging of Geographic Atrophy Investigative Ophthalmology & Visual Science. May, 2013 | Pubmed ID: 23620431 A Single Intravenous AAV9 Injection Mediates Bilateral Gene Transfer to the Adult Mouse Retina PloS One. 2013 | Pubmed ID: 23613884 Using Spectral-domain Optical Coherence Tomography Imaging to Identify the Presence of Retinal Silicone Oil Emulsification After Silicone Oil Tamponade Retina (Philadelphia, Pa.). Sep, 2013 | Pubmed ID: 23591533 Évaluation Toxicologique in Vitro Des Argiles Pour Leur Utilisation Dans Des Applications D'emballage Alimentaire Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association. Jul, 2013 | Pubmed ID: 23579166 Functional Rescue of Cone Photoreceptors in Retinitis Pigmentosa Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Jul, 2013 | Pubmed ID: 23575948 A Semi-automated Computer Tool for the Analysis of Retinal Vessel Diameter Dynamics Computers in Biology and Medicine. Jun, 2013 | Pubmed ID: 23566397 The Detection of Motion by Blind Subjects With the Epiretinal 60-Electrode (Argus II) Retinal Prosthesis JAMA Ophthalmology. Feb, 2013 | Pubmed ID: 23544203 [Therapeutic Innovation in AMD and Other Retinal Diseases] La Revue Du Praticien. Jan, 2013 | Pubmed ID: 23457831 [Ophthalmology, Between Spectacular Advances and Gaps in Managed Care] La Revue Du Praticien. Jan, 2013 | Pubmed ID: 23457825 Seven New Loci Associated with Age-related Macular Degeneration Nature Genetics. Apr, 2013 | Pubmed ID: 23455636 Evaluation of the Taurine Concentrations in Dog Plasma and Aqueous Humour: a Pilot Study Advances in Experimental Medicine and Biology. 2013 | Pubmed ID: 23392931 Taurine is a Crucial Factor to Preserve Retinal Ganglion Cell Survival Advances in Experimental Medicine and Biology. 2013 | Pubmed ID: 23392925 Relative Frequencies of Inherited Retinal Dystrophies and Optic Neuropathies in Southern France: Assessment of 21-year Data Management Ophthalmic Epidemiology. 2013 | Pubmed ID: 23350551 Findings in Detection of Herpesviridae by Polymerase Chain Reaction and Intraocular Antibody Production in a Case Series of Anterior Uveitis Ocular Immunology and Inflammation. 2013 | Pubmed ID: 23323583 Whole-exome Sequencing Identifies LRIT3 Mutations As a Cause of Autosomal-recessive Complete Congenital Stationary Night Blindness American Journal of Human Genetics. Jan, 2013 | Pubmed ID: 23246293 Présence Et La Bioaccumulation De Microcystines Et Cylindrospermopsine Dans Les Aliments Et L'efficacité De Certaines Techniques De Cuisson à Diminuer Leur Concentration : Une Revue Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association. Mar, 2013 | Pubmed ID: 23200893 Neural Stimulation for Visual Rehabilitation: Advances and Challenges Journal of Physiology, Paris. Nov, 2013 | Pubmed ID: 23148976 Dry Age-related Macular Degeneration: A Currently Unmet Clinical Need Intractable & Rare Diseases Research. Aug, 2012 | Pubmed ID: 25343081 Taurine Provides Neuroprotection Against Retinal Ganglion Cell Degeneration PloS One. 2012 | Pubmed ID: 23115615 Localization of Usher 1 Proteins to the Photoreceptor Calyceal Processes, Which Are Absent from Mice The Journal of Cell Biology. Oct, 2012 | Pubmed ID: 23045546 Neuroglobin Involvement in Respiratory Chain Function and Retinal Ganglion Cell Integrity Biochimica Et Biophysica Acta. Dec, 2012 | Pubmed ID: 23036890 En Face OCT Imaging for the Diagnosis of Outer Retinal Tubulations in Age-Related Macular Degeneration Journal of Ophthalmology. 2012 | Pubmed ID: 22970349 L'influence De L'exposition Façon Et Le Moment Du Sacrifice Sur Les Effets Induits Par Une Dose Unique De Pure Cylindrospermopsine Sur L'activité Et La Transcription De La Glutathion Peroxydase Et Glutathion-S-transférase Enzymes Chez Le Tilapia (Oreochromis Niloticus) Chemosphere. Jul, 2012 | Pubmed ID: 22850279 NMNAT1 Mutations Cause Leber Congenital Amaurosis Nature Genetics. Sep, 2012 | Pubmed ID: 22842227 Modifications Observées Dans La Lignée De Cellules Endothéliale HUVEC Exposée à Cylindrospermopsine Pur Chemosphere. Jul, 2012 | Pubmed ID: 22818884 Treating Retinal Vein Occlusions in France, Germany, and Italy: an Analysis of Treatment Patterns, Resource Consumption, and Costs European Journal of Ophthalmology. Sep-Oct, 2012 | Pubmed ID: 22729442 Genome-wide Association Study of Age-related Macular Degeneration Identifies Associated Variants in the TNXB-FKBPL-NOTCH4 Region of Chromosome 6p21.3 Human Molecular Genetics. Sep, 2012 | Pubmed ID: 22694956 Spectral Domain Optical Coherence Tomography Evolutive Features in Acute Macular Neuroretinopathy European Journal of Ophthalmology. Sep-Oct, 2012 | Pubmed ID: 22610717 Rôle Protecteur De La N-acétylcystéine Diététique Sur Le Stress Oxydatif Induit Par Cylindrospermopsine Chez Le Tilapia (Oreochromis Niloticus) Environmental Toxicology and Chemistry / SETAC. Jul, 2012 | Pubmed ID: 22511408 Taurine Deficiency Damages Retinal Neurones: Cone Photoreceptors and Retinal Ganglion Cells Amino Acids. Nov, 2012 | Pubmed ID: 22476345 Les Réactions Au Stress Oxydatif Acide Carboxylique Fonctionnalisés De Nanotubes De Carbone Monoparois Sur La Ligne Des Cellules Intestinales Humaines Caco-2 Toxicology in Vitro : an International Journal Published in Association with BIBRA. Aug, 2012 | Pubmed ID: 22449549 Temporal Properties of Visual Perception on Electrical Stimulation of the Retina Investigative Ophthalmology & Visual Science. May, 2012 | Pubmed ID: 22447863 Nxnl2 Splicing Results in Dual Functions in Neuronal Cell Survival and Maintenance of Cell Integrity Human Molecular Genetics. May, 2012 | Pubmed ID: 22343139 L'exposition Aiguë à Pure Résultats Cylindrospermopsine Du Stress Oxydatif Et Altérations Pathologiques Dans Tilapia (Oreochromis Niloticus) Environmental Toxicology. Feb, 2012 | Pubmed ID: 22331699 Le Séquençage De L'exome-ensemble Identifie Des Mutations GPR179 Menant à Transmission Autosomique Récessive Complète Cécité Nocturne Stationnaire Congénitale American Journal of Human Genetics. Feb, 2012 | Pubmed ID: 22325361 Development and Application of a Next-generation-sequencing (NGS) Approach to Detect Known and Novel Gene Defects Underlying Retinal Diseases Orphanet Journal of Rare Diseases. 2012 | Pubmed ID: 22277662 Interim Results from the International Trial of Second Sight's Visual Prosthesis Ophthalmology. Apr, 2012 | Pubmed ID: 22244176 Biochimiques Et Pathologiques Des Effets Toxiques Induits Par L'cyanotoxines Cylindrospermopsine Sur La Lignée Cellulaire Humaine Caco-2 Water Research. Apr, 2012 | Pubmed ID: 22227240 Downregulation of Apoptosis-inducing Factor in Harlequin Mice Induces Progressive and Severe Optic Atrophy Which is Durably Prevented by AAV2-AIF1 Gene Therapy Brain : a Journal of Neurology. Jan, 2012 | Pubmed ID: 22120150 CRB1 Mutations in Inherited Retinal Dystrophies Human Mutation. Feb, 2012 | Pubmed ID: 22065545 RP1 and Autosomal Dominant Rod-cone Dystrophy: Novel Mutations, a Review of Published Variants, and Genotype-phenotype Correlation Human Mutation. Jan, 2012 | Pubmed ID: 22052604 En Fonction Du Temps Des Changements Histopathologiques Induites Dans Tilapia (Oreochromis Niloticus) Après Une Exposition Aiguë à Cylindrospermopsine Pure Par Voie Orale Et Par Voie Intrapéritonéale Ecotoxicology and Environmental Safety. Feb, 2012 | Pubmed ID: 22019311 A Regulatory Domain is Required for Foxn4 Activity During Retinogenesis Journal of Molecular Neuroscience : MN. Feb, 2012 | Pubmed ID: 21701787 ℮-conome: an Automated Tissue Counting Platform of Cone Photoreceptors for Rodent Models of Retinitis Pigmentosa BMC Ophthalmology. 2011 | Pubmed ID: 22185426 Transcriptomic Analysis of Human Retinal Detachment Reveals Both Inflammatory Response and Photoreceptor Death PloS One. 2011 | Pubmed ID: 22174898 Reevaluation of Dystrophin Localization in the Mouse Retina Investigative Ophthalmology & Visual Science. 2011 | Pubmed ID: 21896869 CYFIP Dependent Actin Remodeling Controls Specific Aspects of Drosophila Eye Morphogenesis Developmental Biology. Nov, 2011 | Pubmed ID: 21884694 Foveal Shape and Structure in a Normal Population Investigative Ophthalmology & Visual Science. Jul, 2011 | Pubmed ID: 21803966 A Novel DFNB31 Mutation Associated with Usher Type 2 Syndrome Showing Variable Degrees of Auditory Loss in a Consanguineous Portuguese Family Molecular Vision. 2011 | Pubmed ID: 21738389 Real-time Polymerase Chain Reaction and Intraocular Antibody Production for the Diagnosis of Viral Versus Toxoplasmic Infectious Posterior Uveitis Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Dec, 2011 | Pubmed ID: 21732111 Flat Choroidal Nevus Inaccessible to Ultrasound Sonography Evaluated by Enhanced Depth Imaging Optical Coherence Tomography Case Reports in Ophthalmology. May, 2011 | Pubmed ID: 21720534 Les Réponses Du Stress Oxydatif Dans Le Tilapia (Oreochromis Niloticus) Exposés à Une Dose Unique De Cylindrospermopsine Pure Dans Des Conditions De Laboratoire: Influence De La Voie D'exposition Et De L'heure Du Sacrifice Aquatic Toxicology (Amsterdam, Netherlands). Sep, 2011 | Pubmed ID: 21703978 Effets Aigus De La Pure Cylindrospermopsine Sur L'activité Et De Transcription Des Enzymes Antioxydantes Dans Le Tilapia (Oreochromis Niloticus) Exposés Par Gavage Ecotoxicology (London, England). Nov, 2011 | Pubmed ID: 21695509 Influence De La Fonctionnalisation Acide Carboxylique Sur Les Effets Cytotoxiques Induites Par Nanotubes De Carbone Monoparois Sur Cellules Endothéliales Humaines (HUVEC) Toxicology in Vitro : an International Journal Published in Association with BIBRA. Dec, 2011 | Pubmed ID: 21651974 Outer Retinal Cysts in Age-related Macular Degeneration Acta Ophthalmologica. Sep, 2011 | Pubmed ID: 21631905 Quality Versus Quantity: Assessing Individual Research Performance Science Translational Medicine. May, 2011 | Pubmed ID: 21613620 Spotlight on Childhood Blindness The Journal of Clinical Investigation. Jun, 2011 | Pubmed ID: 21606601 La Toxicité Et L'implication Glutathion Dans Les Effets Observés Par L'exposition De La Lignée Cellulaire De Foie De Poisson PLHC-1 à Pure Cylindrospermopsine Ecotoxicology and Environmental Safety. Sep, 2011 | Pubmed ID: 21570723 Complete Exon Sequencing of All Known Usher Syndrome Genes Greatly Improves Molecular Diagnosis Orphanet Journal of Rare Diseases. 2011 | Pubmed ID: 21569298 Subretinal Lymphomatous Infiltration in Primary Intraocular Lymphoma Revealed by Optical Coherence Tomography Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Sep, 2011 | Pubmed ID: 21509532 Novel C2orf71 Mutations Account for ∼1% of Cases in a Large French ArRP Cohort Human Mutation. Apr, 2011 | Pubmed ID: 21412943 Topography of Patchy Retinal Whitening During Acute Perfused Retinal Vein Occlusion by Optical Coherence Tomography and Adaptive Optics Fundus Imaging European Journal of Ophthalmology. Sep-Oct, 2011 | Pubmed ID: 21360483 Foveal Damage in Habitual Poppers Users Archives of Ophthalmology. Jun, 2011 | Pubmed ID: 21320953 Effets Sous-chroniques De Cellules De Cyanobactéries Sur La Transcription Des Gènes Des Enzymes Antioxydantes Chez Le Tilapia (Oreochromis Niloticus) Ecotoxicology (London, England). Mar, 2011 | Pubmed ID: 21279735 Gene Therapy in Ophthalmology: Validation on Cultured Retinal Cells and Explants from Postmortem Human Eyes Human Gene Therapy. May, 2011 | Pubmed ID: 21142470 Mammalian Retinal Horizontal Cells Are Unconventional GABAergic Neurons Journal of Neurochemistry. Feb, 2011 | Pubmed ID: 21091475 Interaction Study Between RtPA and Bevacizumab The British Journal of Ophthalmology. May, 2011 | Pubmed ID: 20870640 Mitochondrial Medicine: to a New Era of Gene Therapy for Mitochondrial DNA Mutations Journal of Inherited Metabolic Disease. Apr, 2011 | Pubmed ID: 20571866 Fungal Keratitis in France Acta Ophthalmologica. Mar, 2011 | Pubmed ID: 20529076 Cellular-resolution in Vivo Imaging of the Feline Retina Using Adaptive Optics: Preliminary Results Veterinary Ophthalmology. Nov, 2010 | Pubmed ID: 21182721 Transplantation of Photoreceptor and Total Neural Retina Preserves Cone Function in P23H Rhodopsin Transgenic Rat PloS One. 2010 | Pubmed ID: 20976047 Expression of Rod-derived Cone Viability Factor: Dual Role of CRX in Regulating Promoter Activity and Cell-type Specificity PloS One. 2010 | Pubmed ID: 20949100 Poppers-associated Retinal Toxicity The New England Journal of Medicine. Oct, 2010 | Pubmed ID: 20942681 Prevalence and Novelty of PRPF31 Mutations in French Autosomal Dominant Rod-cone Dystrophy Patients and a Review of Published Reports BMC Medical Genetics. 2010 | Pubmed ID: 20939871 An Unusual Retinal Phenotype Associated with a Novel Mutation in RHO Archives of Ophthalmology. Aug, 2010 | Pubmed ID: 20697005 Dans L'évaluation in Vitro De Cytotoxicité Et Génotoxicité D'un Alliage De Titane Commercial Pour L'implantologie Dentaire Mutation Research. Sep, 2010 | Pubmed ID: 20615479 In Vivo Observation of the Locomotion of Microglial Cells in the Retina Glia. Nov, 2010 | Pubmed ID: 20578032 Targeting the Kallikrein-kinin System As a New Therapeutic Approach to Diabetic Retinopathy Current Opinion in Investigational Drugs (London, England : 2000). May, 2010 | Pubmed ID: 20419596 Rod-derived Cone Viability Factor for Treating Blinding Diseases: from Clinic to Redox Signaling Science Translational Medicine. Apr, 2010 | Pubmed ID: 20375363 [TRPM1, a New Gene Implicated in Congenital Stationary Night Blindness] Médecine Sciences : M/S. Mar, 2010 | Pubmed ID: 20346272 EYS is a Major Gene for Rod-cone Dystrophies in France Human Mutation. May, 2010 | Pubmed ID: 20333770 Spectrum of Rhodopsin Mutations in French Autosomal Dominant Rod-cone Dystrophy Patients Investigative Ophthalmology & Visual Science. Jul, 2010 | Pubmed ID: 20164459 Microcystine-LR Induit Des Effets Toxiques Dans Différenciés Et Non Différenciés Cellules Caco-2 Archives of Toxicology. May, 2010 | Pubmed ID: 20112101 Cytomegalovirus Retinitis Associated with Good's Syndrome European Journal of Ophthalmology. Mar-Apr, 2010 | Pubmed ID: 19882506 The Homeobox Gene CHX10/VSX2 Regulates RdCVF Promoter Activity in the Inner Retina Human Molecular Genetics. Jan, 2010 | Pubmed ID: 19843539 Les Réponses Différentielles Stress Oxydatif Pur Microcystine-LR Et La Microcystine-contenant Et Non Contenant Des Cyanobactéries Extraits Bruts Sur Cellules Caco-2 Toxicon : Official Journal of the International Society on Toxinology. Feb-Mar, 2010 | Pubmed ID: 19825385 Imaging of Macroaneurysms Occurring During Retinal Vein Occlusion and Diabetic Retinopathy by Indocyanine Green Angiography and High Resolution Optical Coherence Tomography Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Feb, 2010 | Pubmed ID: 19701812 TRPM1 is Mutated in Patients with Autosomal-recessive Complete Congenital Stationary Night Blindness American Journal of Human Genetics. Nov, 2009 | Pubmed ID: 19896113 Functional Implication of Dp71 in Osmoregulation and Vascular Permeability of the Retina PloS One. 2009 | Pubmed ID: 19809515 Stress Oxydatif Induit Par La Microcystine-LR Sur PLHC-1 Ligne De Cellules De Poisson Toxicology in Vitro : an International Journal Published in Association with BIBRA. Dec, 2009 | Pubmed ID: 19720136 La Cytotoxicité De L'acide Carboxylique Fonctionnalisé Nanotubes De Carbone Monoparois Sur La Lignée Cellulaire Intestinale Humaine Caco-2 Toxicology in Vitro : an International Journal Published in Association with BIBRA. Dec, 2009 | Pubmed ID: 19591917 Genotyping Microarray for CSNB-associated Genes Investigative Ophthalmology & Visual Science. Dec, 2009 | Pubmed ID: 19578023 Le Glutathion Dans Les Lignées Cellulaires De Poisson CBE Et BCF-2: Réponse à La Pro Model-oxydants Tels Que Mesurés Par Trois Différents Colorants Fluorescents Toxicology in Vitro : an International Journal Published in Association with BIBRA. Apr, 2009 | Pubmed ID: 19444932 The Thioredoxin-like Protein Rod-derived Cone Viability Factor (RdCVFL) Interacts with TAU and Inhibits Its Phosphorylation in the Retina Molecular & Cellular Proteomics : MCP. Jun, 2009 | Pubmed ID: 19279044 Functional Cone Rescue by RdCVF Protein in a Dominant Model of Retinitis Pigmentosa Molecular Therapy : the Journal of the American Society of Gene Therapy. May, 2009 | Pubmed ID: 19277021 Identification of Anastomosis Between the Central Retinal Artery and the Central Retinal Vein in a Case of Central Retinal Vein Occlusion Due to Arteriovenous Malformation Retinal Cases & Brief Reports. 2008 | Pubmed ID: 25390603 Optimized Allotopic Expression of the Human Mitochondrial ND4 Prevents Blindness in a Rat Model of Mitochondrial Dysfunction American Journal of Human Genetics. Sep, 2008 | Pubmed ID: 18771762 The Optimized Allotopic Expression of ND1 or ND4 Genes Restores Respiratory Chain Complex I Activity in Fibroblasts Harboring Mutations in These Genes Biochimica Et Biophysica Acta. Oct, 2008 | Pubmed ID: 18513491 Association Between Visual Acuity and Medical and Non-medical Costs in Patients with Wet Age-related Macular Degeneration in France, Germany and Italy Drugs & Aging. 2008 | Pubmed ID: 18331076 [mRNA Localization to the Mitochondrial Surface: a Tool to Treat Retinal Pathologies Due to Mitochondrial DNA Mutations] Journal De La Société De Biologie. 2007 | Pubmed ID: 17762826 Health-related Quality of Life and Utility in Patients with Age-related Macular Degeneration Archives of Ophthalmology. Jul, 2007 | Pubmed ID: 17620576 Panretinal, High-resolution Color Photography of the Mouse Fundus Investigative Ophthalmology & Visual Science. Jun, 2007 | Pubmed ID: 17525211 Allotopic MRNA Localization to the Mitochondrial Surface Rescues Respiratory Chain Defects in Fibroblasts Harboring Mitochondrial DNA Mutations Affecting Complex I or V Subunits Rejuvenation Research. Jun, 2007 | Pubmed ID: 17518546 The Loss of Transcriptional Inhibition by the Photoreceptor-cell Specific Nuclear Receptor (NR2E3) is Not a Necessary Cause of Enhanced S-cone Syndrome Molecular Vision. 2007 | Pubmed ID: 17438525 Retinal Degenerations: from Cell Signaling to Cell Therapy; Pre-clinical and Clinical Issues Current Gene Therapy. Apr, 2007 | Pubmed ID: 17430131 Anxiety and Depression Prevalence Rates in Age-related Macular Degeneration Investigative Ophthalmology & Visual Science. Apr, 2007 | Pubmed ID: 17389477 [Retinal Repair by Transplantation of Photoreceptor Precursors] Médecine Sciences : M/S. Mar, 2007 | Pubmed ID: 17349277 Use of Suppression Subtractive Hybridization to Identify Genes Regulated by Ciliary Neurotrophic Factor in Postnatal Retinal Explants Molecular Vision. 2007 | Pubmed ID: 17327826 Disease-associated Variants of the Rod-derived Cone Viability Factor (RdCVF) in Leber Congenital Amaurosis. Rod-derived Cone Viability Variants in LCA Advances in Experimental Medicine and Biology. 2006 | Pubmed ID: 17249548 The Glutamate Transporter EAAT5 Works As a Presynaptic Receptor in Mouse Rod Bipolar Cells The Journal of Physiology. Nov, 2006 | Pubmed ID: 16973698 Involvement of Pleiotrophin in CNTF-mediated Differentiation of the Late Retinal Progenitor Cells Developmental Biology. Oct, 2006 | Pubmed ID: 16914133 PromAn: an Integrated Knowledge-based Web Server Dedicated to Promoter Analysis Nucleic Acids Research. Jul, 2006 | Pubmed ID: 16845074 Cone Dysfunction As a Paraneoplastic Syndrome Associated with Retinal Antigens Approximating 40 KiloDalton Ophthalmic Genetics. Jun, 2006 | Pubmed ID: 16754207 MRNA Localization to the Mitochondrial Surface Allows the Efficient Translocation Inside the Organelle of a Nuclear Recoded ATP6 Protein RNA (New York, N.Y.). Jul, 2006 | Pubmed ID: 16751614 High Resolution Fundus Imaging by Confocal Scanning Laser Ophthalmoscopy in the Mouse Vision Research. Apr, 2006 | Pubmed ID: 16289196 Saving Cone Cells in Hereditary Rod Diseases: a Possible Role for Rod-derived Cone Viability Factor (RdCVF) Therapy Retina (Philadelphia, Pa.). Dec, 2005 | Pubmed ID: 16374327 Optical Coherence Tomography Findings in Tamoxifen Retinopathy American Journal of Ophthalmology. Oct, 2005 | Pubmed ID: 16226541 Evidence for Glutamate-mediated Excitotoxic Mechanisms During Photoreceptor Degeneration in the Rd1 Mouse Retina Molecular Vision. 2005 | Pubmed ID: 16163266 Does GDNF Exert Its Neuroprotective Effects on Photoreceptors in the Rd1 Retina Through the Glial Glutamate Transporter GLAST? Molecular Vision. 2005 | Pubmed ID: 16163265 Rhodopsin Maturation Defects Induce Photoreceptor Death by Apoptosis: a Fly Model for RhodopsinPro23His Human Retinitis Pigmentosa Human Molecular Genetics. Sep, 2005 | Pubmed ID: 16049034 Retinal-cell-conditioned Medium Prevents TNF-alpha-induced Apoptosis of Purified Ganglion Cells Investigative Ophthalmology & Visual Science. Aug, 2005 | Pubmed ID: 16043875 The Sarcoglycan-sarcospan Complex Localization in Mouse Retina is Independent from Dystrophins Neuroscience Research. Sep, 2005 | Pubmed ID: 15993965 Molecular Cloning and Protein Expression of Duchenne Muscular Dystrophy Gene Products in Porcine Retina Neuromuscular Disorders : NMD. Jul, 2005 | Pubmed ID: 15941659 Role of Hyaluronidase in Diplopia After Peribulbar Anesthesia for Cataract Surgery Ophthalmology. May, 2005 | Pubmed ID: 15878070 [Neuroprotection of Photoreceptor Cells in Rod-cone Dystrophies: from Cell Therapy to Cell Signalling] Comptes Rendus Biologies. Feb, 2005 | Pubmed ID: 15771002 [Rod-derived Cone Viability Factor: a Clue for Therapy of Retinitis Pigmentosa?] Médecine Sciences : M/S. Jan, 2005 | Pubmed ID: 15639013 Identification of Gene Expression Changes Associated with the Progression of Retinal Degeneration in the Rd1 Mouse Investigative Ophthalmology & Visual Science. Sep, 2004 | Pubmed ID: 15326104 Identification and Characterization of Rod-derived Cone Viability Factor Nature Genetics. Jul, 2004 | Pubmed ID: 15220920 Inherited Retinal Degenerations: Therapeutic Prospects Biology of the Cell / Under the Auspices of the European Cell Biology Organization. May, 2004 | Pubmed ID: 15145530 The Search for Rod-dependent Cone Viability Factors, Secreted Factors Promoting Cone Viability Novartis Foundation Symposium. 2004 | Pubmed ID: 14750600 The Aging of the Retina Experimental Gerontology. Aug, 2003 | Pubmed ID: 12915204 Differential Proteomic Analysis of the Mouse Retina: the Induction of Crystallin Proteins by Retinal Degeneration in the Rd1 Mouse Molecular & Cellular Proteomics : MCP. Aug, 2003 | Pubmed ID: 12832458 [Retinitis Pigmentosa: Pathogenic Progress and Therapeutic Hopes] La Revue Du Praticien. Oct, 2002 | Pubmed ID: 12564163 Prenatal Human Ocular Degeneration Occurs in Leber's Congenital Amaurosis (LCA2) The Journal of Gene Medicine. Jul-Aug, 2002 | Pubmed ID: 12124981 Cellular Localization of the Vesicular Inhibitory Amino Acid Transporter in the Mouse and Human Retina The Journal of Comparative Neurology. Jul, 2002 | Pubmed ID: 12115694 Cultures enrichies en cônes de la rétine d’embryons de poulet pour étudier les interactions cellulaires entre tiges et cônes Géraldine Millet-Puel1, Myriam Pinault1, Marie Cordonnier1, Valérie Fontaine1, José-Alain Sahel1, Thierry Léveillard1 1Department of Genetics - Sorbonne Université, INSERM, CNRS, Institut de la Vision JoVE 61998 Neuroscience Xeno-libre défini et exempte d’engraissement des Conditions de Culture pour les modèles de cellule rétinienne Generation of Human dérivés iPSC Amélie Slembrouck-Brec*1, Céline Nanteau*1, José-Alain Sahel1, Olivier Goureau1, Sacha Reichman1 1Institut de la Vision, Sorbonne Université, INSERM, CNRS, F-75012 Paris, France JoVE 57795 Developmental Biology Utilisant le virus adéno-associé comme un outil pour étudier les obstacles dans la maladie de la rétine Ophélie Vacca1,2,3, Brahim El Mathari1,2,3, Marie Darche1,2,3, José-Alain Sahel1,2,3, Alvaro Rendon1,2,3, Deniz Dalkara1,2,3 1Department of Therapeutics, Institut de la Vision, Sorbonne Universtés, UPMC Univ Paris 06, UMR_S 968, 2INSERM, U968, 3CNRS, UMR_7210 Medicine Vibratome sectionnement rétine de souris pour préparer des cultures photoréceptrices Emmanuelle Clérin1,4,5,6, Ying Yang1,4,5,6, Valérie Forster2,4,5,6, Valérie Fontaine3,4,5,6, José-Alain Sahel4,5,6, Thierry Léveillard1,4,5,6 1Department of Genetics, UMR_S 968, Institut de la Vision, 2Department of Visual Information, UMR_S 968, Institut de la Vision, 3Exploratory Team, UMR_S 968, Institut de la Vision, 4Sorbonne Universités, Paris 06, UMR_S 968, Institut de la Vision, 5INSERM, U968, Institut de la Vision, 6CNRS, UMR_7210, Institut de la Vision JoVE 51954 Neuroscience L'analyse transcriptomique de prélèvements rétine humaine en utilisant Journal Marie-Noëlle Delyfer1,2,3,4, Najate Aït-Ali1,2,3, Hawa Camara1,2,3, Emmanuelle Clérin1,2,3, Jean-François Korobelnik4, José-Alain Sahel1,2,3, Thierry Léveillard1,2,3 1U968, Institut National de la Santé et de la Recherche Médicale, 2UMR S 968, Université Pierre et Marie Curie, 3UMR 7210, Centre National de la Recherche Scientifique, 4Départment d'Ophtalmologie, Centre Hospitalier Universitaire de Bordeaux JoVE 50375 Medicine
Cultures enrichies en cônes de la rétine d’embryons de poulet pour étudier les interactions cellulaires entre tiges et cônes Géraldine Millet-Puel1, Myriam Pinault1, Marie Cordonnier1, Valérie Fontaine1, José-Alain Sahel1, Thierry Léveillard1 1Department of Genetics - Sorbonne Université, INSERM, CNRS, Institut de la Vision JoVE 61998 Neuroscience
Xeno-libre défini et exempte d’engraissement des Conditions de Culture pour les modèles de cellule rétinienne Generation of Human dérivés iPSC Amélie Slembrouck-Brec*1, Céline Nanteau*1, José-Alain Sahel1, Olivier Goureau1, Sacha Reichman1 1Institut de la Vision, Sorbonne Université, INSERM, CNRS, F-75012 Paris, France JoVE 57795 Developmental Biology
Utilisant le virus adéno-associé comme un outil pour étudier les obstacles dans la maladie de la rétine Ophélie Vacca1,2,3, Brahim El Mathari1,2,3, Marie Darche1,2,3, José-Alain Sahel1,2,3, Alvaro Rendon1,2,3, Deniz Dalkara1,2,3 1Department of Therapeutics, Institut de la Vision, Sorbonne Universtés, UPMC Univ Paris 06, UMR_S 968, 2INSERM, U968, 3CNRS, UMR_7210 Medicine
Vibratome sectionnement rétine de souris pour préparer des cultures photoréceptrices Emmanuelle Clérin1,4,5,6, Ying Yang1,4,5,6, Valérie Forster2,4,5,6, Valérie Fontaine3,4,5,6, José-Alain Sahel4,5,6, Thierry Léveillard1,4,5,6 1Department of Genetics, UMR_S 968, Institut de la Vision, 2Department of Visual Information, UMR_S 968, Institut de la Vision, 3Exploratory Team, UMR_S 968, Institut de la Vision, 4Sorbonne Universités, Paris 06, UMR_S 968, Institut de la Vision, 5INSERM, U968, Institut de la Vision, 6CNRS, UMR_7210, Institut de la Vision JoVE 51954 Neuroscience
L'analyse transcriptomique de prélèvements rétine humaine en utilisant Journal Marie-Noëlle Delyfer1,2,3,4, Najate Aït-Ali1,2,3, Hawa Camara1,2,3, Emmanuelle Clérin1,2,3, Jean-François Korobelnik4, José-Alain Sahel1,2,3, Thierry Léveillard1,2,3 1U968, Institut National de la Santé et de la Recherche Médicale, 2UMR S 968, Université Pierre et Marie Curie, 3UMR 7210, Centre National de la Recherche Scientifique, 4Départment d'Ophtalmologie, Centre Hospitalier Universitaire de Bordeaux JoVE 50375 Medicine
