Joseph C. Wu Stanford Cardiovascular Institute Stanford University School of Medicine Biography Publications Institution JoVE Articles Joseph C. Wu has not added a biography. If you are Joseph C. Wu and would like to personalize this page please email our Author Liaison for assistance. Publications Contractility and Calcium Transient Maturation in the Human IPSC-Derived Cardiac Microfibers ACS Applied Materials & Interfaces. Jul, 2022 | Pubmed ID: 35901275 Generation of Human Induced Pluripotent Stem Cell Lines Carrying Heterozygous PLN Mutation from Dilated Cardiomyopathy Patients Stem Cell Research. Jul, 2022 | Pubmed ID: 35853412 Human Induced Pluripotent Stem Cells for Studying Mitochondrial Diseases in the Heart FEBS Letters. Jul, 2022 | Pubmed ID: 35788991 Shifting Machine Learning for Healthcare from Development to Deployment and from Models to Data Nature Biomedical Engineering. Jul, 2022 | Pubmed ID: 35788685 A Pilot Clinical Trial of Cell Therapy in Heart Failure with Preserved Ejection Fraction European Journal of Heart Failure. Jul, 2022 | Pubmed ID: 35775390 Cardio- and Neurotoxicity of Selected Anti-COVID-19 Drugs Pharmaceuticals (Basel, Switzerland). Jun, 2022 | Pubmed ID: 35745684 Modeling Susceptibility to Cardiotoxicity in Cancer Therapy Using Human IPSC-Derived Cardiac Cells and Systems Biology Heart Failure Clinics. Jul, 2022 | Pubmed ID: 35718410 Generation of Two Induced Pluripotent Stem Cell Lines Carrying the Phospholamban R14del Mutation for Modeling ARVD/C Stem Cell Research. Jun, 2022 | Pubmed ID: 35700631 HMOX1 Genetic Polymorphisms Display Ancestral Diversity and May Be Linked to Hypertensive Disorders in Pregnancy Reproductive Sciences (Thousand Oaks, Calif.). Jun, 2022 | Pubmed ID: 35697922 Cellular and Engineered Organoids for Cardiovascular Models Circulation Research. Jun, 2022 | Pubmed ID: 35679369 High-Throughput Analysis of Drug Safety Responses in Induced Pluripotent Stem Cell-Derived Cardiomyocytes Using Multielectrode Array Methods in Molecular Biology (Clifton, N.J.). 2022 | Pubmed ID: 35618901 Intersectionality and Genetic Ancestry: New Methods to Solve Old Problems EBioMedicine. 06, 2022 | Pubmed ID: 35561454 Generation of Embryonic Origin-Specific Vascular Smooth Muscle Cells from Human Induced Pluripotent Stem Cells Methods in Molecular Biology (Clifton, N.J.). 2022 | Pubmed ID: 35507165 Modeling Effects of Immunosuppressive Drugs on Human Hearts Using Induced Pluripotent Stem Cell-Derived Cardiac Organoids and Single-Cell RNA Sequencing Circulation. 04, 2022 | Pubmed ID: 35467958 Generation of Two IPSC Lines from Hypertrophic Cardiomyopathy Patients Carrying MYBPC3 and PRKAG2 Variants Stem Cell Research. 05, 2022 | Pubmed ID: 35413566 Progress in Multicellular Human Cardiac Organoids for Clinical Applications Cell Stem Cell. Apr, 2022 | Pubmed ID: 35395186 Population-based High-throughput Toxicity Screen of Human IPSC-derived Cardiomyocytes and Neurons Cell Reports. 04, 2022 | Pubmed ID: 35385754 Ferroptosis of Pacemaker Cells in COVID-19 Circulation Research. 04, 2022 | Pubmed ID: 35357897 Deconvoluting the Cells of the Human Heart with IPSC Technology: Cell Types, Protocols, and Uses Current Cardiology Reports. 05, 2022 | Pubmed ID: 35244869 Activation of PDGFRA Signaling Contributes to Filamin C-related Arrhythmogenic Cardiomyopathy Science Advances. Feb, 2022 | Pubmed ID: 35196083 Vein to Artery: the First Arteriogenesis in the Mammalian Embryo Cell Research. Apr, 2022 | Pubmed ID: 35165423 The Use of New CRISPR Tools in Cardiovascular Research and Medicine Nature Reviews. Cardiology. Aug, 2022 | Pubmed ID: 35145236 Heterozygous LMNA Mutation-carrying IPSC Lines from Three Cardiac Laminopathy Patients Stem Cell Research. Jan, 2022 | Pubmed ID: 34999423 Cardiac Reprogramming Via Chromatin Remodeling by CRISPR Activation Molecular Therapy : the Journal of the American Society of Gene Therapy. 01, 2022 | Pubmed ID: 34895515 Human-induced Pluripotent Stem Cells in Cardiovascular Research: Current Approaches in Cardiac Differentiation, Maturation Strategies, and Scalable Production Cardiovascular Research. 01, 2022 | Pubmed ID: 33757124 Generation of Quiescent Cardiac Fibroblasts Derived from Human Induced Pluripotent Stem Cells Methods in Molecular Biology (Clifton, N.J.). 2022 | Pubmed ID: 32671814 Generation of Three IPSC Lines from Dilated Cardiomyopathy Patients Carrying a Pathogenic LMNA Variant Stem Cell Research. Dec, 2021 | Pubmed ID: 34954454 Modeling Transposition of the Great Arteries with Patient-Specific Induced Pluripotent Stem Cells International Journal of Molecular Sciences. Dec, 2021 | Pubmed ID: 34948064 Preoperative Computed Tomography Angiography Reveals Leaflet-Specific Calcification and Excursion Patterns in Aortic Stenosis Circulation. Cardiovascular Imaging. 12, 2021 | Pubmed ID: 34915729 An Inflammatory Aging Clock (iAge) Based on Deep Learning Tracks Multimorbidity, Immunosenescence, Frailty and Cardiovascular Aging Nature Aging. Jul, 2021 | Pubmed ID: 34888528 Generation of Two Induced Pluripotent Stem Cell Lines from Brugada Syndrome Affected Patients Carrying SCN5A Mutations Stem Cell Research. Nov, 2021 | Pubmed ID: 34856468 Generation of Three Induced Pluripotent Stem Cell Lines from Hypertrophic Cardiomyopathy Patients Carrying TNNI3 Mutations Stem Cell Research. Nov, 2021 | Pubmed ID: 34798544 Basic and Translational Research in Cardiac Repair and Regeneration: JACC State-of-the-Art Review Journal of the American College of Cardiology. 11, 2021 | Pubmed ID: 34794691 Protocol to Measure Contraction, Calcium, and Action Potential in Human-induced Pluripotent Stem Cell-derived Cardiomyocytes STAR Protocols. 12, 2021 | Pubmed ID: 34746854 Altered Cardiac Energetics and Mitochondrial Dysfunction in Hypertrophic Cardiomyopathy Circulation. 11, 2021 | Pubmed ID: 34672721 Adverse Effects of Air Pollution-derived Fine Particulate Matter on Cardiovascular Homeostasis and Disease Trends in Cardiovascular Medicine. Oct, 2021 | Pubmed ID: 34619335 Deciphering Pathogenicity of Variants of Uncertain Significance with CRISPR-edited IPSCs Trends in Genetics : TIG. 12, 2021 | Pubmed ID: 34509299 Leaders in Cardiovascular Research: Joseph C. Wu Cardiovascular Research. 08, 2021 | Pubmed ID: 34435623 Highlights from Stanford Drug Discovery Symposium 2021 Cardiovascular Research. 08, 2021 | Pubmed ID: 34417601 Generation of Three Induced Pluripotent Stem Cell Lines (SCVIi014-A, SCVIi015-A, and SCVIi016-A) from Patients with LQT1 Caused by Heterozygous Mutations in the KCNQ1 Gene Stem Cell Research. 08, 2021 | Pubmed ID: 34411974 Generation of Three Induced Pluripotent Stem Cell Lines from Hypertrophic Cardiomyopathy Patients Carrying MYH7 Mutations Stem Cell Research. 08, 2021 | Pubmed ID: 34352619 CRISPRi/a Screening with Human IPSCs Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 34302664 Endocardial/endothelial Angiocrines Regulate Cardiomyocyte Development and Maturation and Induce Features of Ventricular Non-compaction European Heart Journal. 11, 2021 | Pubmed ID: 34279605 Macrophages: Potential Therapeutic Target of Myocardial Injury in COVID-19 Circulation Research. 06, 2021 | Pubmed ID: 34166080 Generation of Three Heterozygous KCNH2 Mutation-carrying Human Induced Pluripotent Stem Cell Lines for Modeling LQT2 Syndrome Stem Cell Research. 07, 2021 | Pubmed ID: 34051449 Human Induced Pluripotent Stem Cell-derived Atrial Cardiomyocytes Carrying an SCN5A Mutation Identify Nitric Oxide Signaling As a Mediator of Atrial Fibrillation Stem Cell Reports. 06, 2021 | Pubmed ID: 34019817 Increased Tissue Stiffness Triggers Contractile Dysfunction and Telomere Shortening in Dystrophic Cardiomyocytes Stem Cell Reports. 09, 2021 | Pubmed ID: 34019816 Reconstructing the Heart Using IPSCs: Engineering Strategies and Applications Journal of Molecular and Cellular Cardiology. 08, 2021 | Pubmed ID: 33895197 Method for Selective Ablation of Undifferentiated Human Pluripotent Stem Cell Populations for Cell-based Therapies JCI Insight. 04, 2021 | Pubmed ID: 33830086 Generation of Vascular Smooth Muscle Cells From Induced Pluripotent Stem Cells: Methods, Applications, and Considerations Circulation Research. 03, 2021 | Pubmed ID: 33818124 ALDH1A3 Coordinates Metabolism With Gene Regulation in Pulmonary Arterial Hypertension Circulation. 05, 2021 | Pubmed ID: 33764154 Generation of Two Heterozygous MYBPC3 Mutation-carrying Human IPSC Lines, SCVIi001-A and SCVIi002-A, for Modeling Hypertrophic Cardiomyopathy Stem Cell Research. 05, 2021 | Pubmed ID: 33743363 Massive Expansion and Cryopreservation of Functional Human Induced Pluripotent Stem Cell-derived Cardiomyocytes STAR Protocols. 03, 2021 | Pubmed ID: 33615277 Air Pollution Exposure is Linked with Methylation of Immunoregulatory Genes, Altered Immune Cell Profiles, and Increased Blood Pressure in Children Scientific Reports. 02, 2021 | Pubmed ID: 33603036 CRISPR/Cas9-based Targeting of Fluorescent Reporters to Human IPSCs to Isolate Atrial and Ventricular-specific Cardiomyocytes Scientific Reports. 02, 2021 | Pubmed ID: 33542270 Clinical Trial in a Dish: Using Patient-Derived Induced Pluripotent Stem Cells to Identify Risks of Drug-Induced Cardiotoxicity Arteriosclerosis, Thrombosis, and Vascular Biology. 03, 2021 | Pubmed ID: 33472401 Effects of Cryopreservation on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Assessing Drug Safety Response Profiles Stem Cell Reports. 01, 2021 | Pubmed ID: 33338435 Transcriptome Analysis of Non Human Primate-induced Pluripotent Stem Cell-derived Cardiomyocytes in 2D Monolayer Culture Vs. 3D Engineered Heart Tissue Cardiovascular Research. 07, 2021 | Pubmed ID: 33002105 Human-induced Pluripotent Stem Cells for Modelling Metabolic Perturbations and Impaired Bioenergetics Underlying Cardiomyopathies Cardiovascular Research. 02, 2021 | Pubmed ID: 32365198 Atlas of Exosomal MicroRNAs Secreted From Human IPSC-Derived Cardiac Cell Types Circulation. 11, 2020 | Pubmed ID: 33136510 Author Correction: Non-Invasive Photoacoustic Imaging of In Vivo Mice with Erythrocyte Derived Optical Nanoparticles to Detect CAD/MI Scientific Reports. Oct, 2020 | Pubmed ID: 33127974 Primer on Biomarker Discovery in Cardio-Oncology: Application of Omics Technologies JACC. CardioOncology. Sep, 2020 | Pubmed ID: 33073248 Immune Biomarkers Link Air Pollution Exposure to Blood Pressure in Adolescents Environmental Health : a Global Access Science Source. 10, 2020 | Pubmed ID: 33066786 Single-cell Protein Expression of HiPSC-derived Cardiomyocytes Using Single-Cell Westerns Journal of Molecular and Cellular Cardiology. 12, 2020 | Pubmed ID: 33010256 Copy Number Variant Hotspots in Han Taiwanese Population Induced Pluripotent Stem Cell Lines - Lessons from Establishing the Taiwan Human Disease IPSC Consortium Bank Journal of Biomedical Science. Sep, 2020 | Pubmed ID: 32887585 A Computational Model of Induced Pluripotent Stem-cell Derived Cardiomyocytes for High Throughput Risk Stratification of KCNQ1 Genetic Variants PLoS Computational Biology. 08, 2020 | Pubmed ID: 32797034 An Extracellular Matrix Paradox in Myocardial Scar Formation Signal Transduction and Targeted Therapy. 08, 2020 | Pubmed ID: 32788685 Tumor Repressor Circular RNA As a New Target for Preventative Gene Therapy Against Doxorubicin-Induced Cardiotoxicity Circulation Research. 07, 2020 | Pubmed ID: 32762533 Clinical Trial in a Dish Using IPSCs Shows Lovastatin Improves Endothelial Dysfunction and Cellular Cross-talk in LMNA Cardiomyopathy Science Translational Medicine. 07, 2020 | Pubmed ID: 32727917 COVID-19 and Cardiovascular Disease: from Basic Mechanisms to Clinical Perspectives Nature Reviews. Cardiology. 09, 2020 | Pubmed ID: 32690910 Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cell Reports. 07, 2020 | Pubmed ID: 32668256 Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human IPSC-Derived Cardiomyocytes Cell Stem Cell. 07, 2020 | Pubmed ID: 32619518 High-throughput Preparation of DNA, RNA, and Protein from Cryopreserved Human IPSCs for Multi-omics Analysis Current Protocols in Stem Cell Biology. 09, 2020 | Pubmed ID: 32584494 Molecular Imaging of Infective Endocarditis With 6''-[F]Fluoromaltotriose Positron Emission Tomography-Computed Tomography Circulation. 05, 2020 | Pubmed ID: 32453662 Levitating Cells to Sort the Fit and the Fat Advanced Biosystems. 06, 2020 | Pubmed ID: 32352239 Molecular Signatures of Beneficial Class Effects of Statins on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Circulation. 04, 2020 | Pubmed ID: 32250699 Non-Invasive Photoacoustic Imaging of In Vivo Mice with Erythrocyte Derived Optical Nanoparticles to Detect CAD/MI Scientific Reports. 04, 2020 | Pubmed ID: 32249814 Single-cell RNA Sequencing in Cardiovascular Development, Disease and Medicine Nature Reviews. Cardiology. Mar, 2020 | Pubmed ID: 32231331 Gut Microbiota and Cardiovascular Disease: Opportunities and Challenges Microbiome. Mar, 2020 | Pubmed ID: 32169105 Pharmacological Silencing of MicroRNA-152 Prevents Pressure Overload-Induced Heart Failure Circulation. Heart Failure. Mar, 2020 | Pubmed ID: 32160771 Using Bioengineered Bioluminescence to Track Stem Cell Transplantation In Vivo Methods in Molecular Biology (Clifton, N.J.). 2020 | Pubmed ID: 32112374 Therapeutic Genome Editing in Cardiovascular Diseases Advanced Drug Delivery Reviews. Feb, 2020 | Pubmed ID: 32092381 RNA Sequencing Analysis of Induced Pluripotent Stem Cell-Derived Cardiomyocytes From Congenital Heart Disease Patients Circulation Research. Mar, 2020 | Pubmed ID: 32070195 Reversible Mitochondrial Fragmentation in IPSC-Derived Cardiomyocytes From Children With DCMA, a Mitochondrial Cardiomyopathy The Canadian Journal of Cardiology. Apr, 2020 | Pubmed ID: 32046906 Total Microfluidic Chip for Multiplexed Diagnostics (ToMMx) Biosensors & Bioelectronics. Feb, 2020 | Pubmed ID: 31929083 Improving the Engraftment and Integration of Cell Transplantation for Cardiac Regeneration Cardiovascular Research. Mar, 2020 | Pubmed ID: 31504255 Electronic Cigarettes: Where There Is Smoke There Is Disease Journal of the American College of Cardiology. Dec, 2019 | Pubmed ID: 31856968 Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function Stem Cell Reports. 12, 2019 | Pubmed ID: 31708475 Workshop Report: FDA Workshop on Improving Cardiotoxicity Assessment With Human-Relevant Platforms Circulation Research. Oct, 2019 | Pubmed ID: 31600125 Nanoscale Technologies for Prevention and Treatment of Heart Failure: Challenges and Opportunities Chemical Reviews. 11, 2019 | Pubmed ID: 31490059 Towards Precision Medicine With Human IPSCs for Cardiac Channelopathies Circulation Research. Aug, 2019 | Pubmed ID: 31465267 Induced Pluripotent Stem Cells As a Novel Cancer Vaccine Expert Opinion on Biological Therapy. 11, 2019 | Pubmed ID: 31364894 Atheroprotective Roles of Smooth Muscle Cell Phenotypic Modulation and the TCF21 Disease Gene As Revealed by Single-cell Analysis Nature Medicine. 08, 2019 | Pubmed ID: 31359001 Clinical Trial in a Dish: Personalized Stem Cell-Derived Cardiomyocyte Assay Compared With Clinical Trial Results for Two QT-Prolonging Drugs Clinical and Translational Science. Nov, 2019 | Pubmed ID: 31328865 Activation of PDGF Pathway Links LMNA Mutation to Dilated Cardiomyopathy Nature. 08, 2019 | Pubmed ID: 31316208 Generation of Quiescent Cardiac Fibroblasts From Human Induced Pluripotent Stem Cells for In Vitro Modeling of Cardiac Fibrosis Circulation Research. Aug, 2019 | Pubmed ID: 31288631 Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution Circulation Research. Aug, 2019 | Pubmed ID: 31284824 A Computational Model of Induced Pluripotent Stem-cell Derived Cardiomyocytes Incorporating Experimental Variability from Multiple Data Sources The Journal of Physiology. Sep, 2019 | Pubmed ID: 31278749 Modelling Diastolic Dysfunction in Induced Pluripotent Stem Cell-derived Cardiomyocytes from Hypertrophic Cardiomyopathy Patients European Heart Journal. Dec, 2019 | Pubmed ID: 31219556 A Combination of Itraconazole and Amiodarone Is Highly Effective Against Infection of Human Stem Cell-Derived Cardiomyocytes The American Journal of Tropical Medicine and Hygiene. 08, 2019 | Pubmed ID: 31219005 Modeling Cardiovascular Risks of E-Cigarettes With Human-Induced Pluripotent Stem Cell-Derived Endothelial Cells Journal of the American College of Cardiology. 06, 2019 | Pubmed ID: 31146818 Single Cell Expression Analysis Reveals Anatomical and Cell Cycle-dependent Transcriptional Shifts During Heart Development Development (Cambridge, England). Jun, 2019 | Pubmed ID: 31142541 RRAD Mutation Causes Electrical and Cytoskeletal Defects in Cardiomyocytes Derived from a Familial Case of Brugada Syndrome European Heart Journal. Oct, 2019 | Pubmed ID: 31114854 Proteasome-Dependent Regulation of Distinct Metabolic States During Long-Term Culture of Human IPSC-Derived Cardiomyocytes Circulation Research. 06, 2019 | Pubmed ID: 31104567 Identifying the Transcriptome Signatures of Calcium Channel Blockers in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Circulation Research. Jul, 2019 | Pubmed ID: 31079550 The West Coast Regional Safety Pharmacology Society Meeting Update: Filling Translational Gaps in Safety Assessment Journal of Pharmacological and Toxicological Methods. Jul - Aug, 2019 | Pubmed ID: 31077805 Stanford Cardiovascular Institute Circulation Research. 05, 2019 | Pubmed ID: 31070998 Complex Heritability in Cardiomyopathy Nature Biomedical Engineering. 02, 2019 | Pubmed ID: 30944437 A Human IPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles Cell Stem Cell. 05, 2019 | Pubmed ID: 30880024 Human-Induced Pluripotent Stem Cell Model of Trastuzumab-Induced Cardiac Dysfunction in Patients With Breast Cancer Circulation. 05, 2019 | Pubmed ID: 30866650 Single-Cell RNA Sequencing of Human Embryonic Stem Cell Differentiation Delineates Adverse Effects of Nicotine on Embryonic Development Stem Cell Reports. 04, 2019 | Pubmed ID: 30827876 Personalized Medicine in Cardio-oncology: the Role of Induced Pluripotent Stem Cell Cardiovascular Research. 04, 2019 | Pubmed ID: 30768178 Myocardial Viability of the Peri-infarct Region Measured by T1 Mapping Post Manganese-enhanced MRI Correlates with LV Dysfunction International Journal of Cardiology. Apr, 2019 | Pubmed ID: 30739802 Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure Circulation Research. Jan, 2019 | Pubmed ID: 30605412 A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy Via Chronic Activation of Nonsense-Mediated Decay Circulation. 02, 2019 | Pubmed ID: 30586709 Progress, Obstacles, and Limitations in the Use of Stem Cells in Organ-on-a-chip Models Advanced Drug Delivery Reviews. 02, 2019 | Pubmed ID: 29885330 Cancer Therapy-induced Cardiomyopathy: Can Human Induced Pluripotent Stem Cell Modelling Help Prevent It? European Heart Journal. Jun, 2019 | Pubmed ID: 29377985 Harnessing Cell Pluripotency for Cardiovascular Regenerative Medicine Nature Biomedical Engineering. 06, 2018 | Pubmed ID: 31011193 Big Bottlenecks in Cardiovascular Tissue Engineering Communications Biology. 2018 | Pubmed ID: 30480100 Defining Human Cardiac Transcription Factor Hierarchies Using Integrated Single-cell Heterogeneity Analysis Nature Communications. 11, 2018 | Pubmed ID: 30464173 Use of Human Induced Pluripotent Stem Cell-derived Cardiomyocytes to Assess Drug Cardiotoxicity Nature Protocols. 12, 2018 | Pubmed ID: 30413796 Strategies for Improving the Maturity of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Circulation Research. 08, 2018 | Pubmed ID: 30355143 From the BCVS Chair Circulation Research. 09, 2018 | Pubmed ID: 30355039 Cytokines Profile of Reverse Cardiac Remodeling Following Transcatheter Aortic Valve Replacement International Journal of Cardiology. Nov, 2018 | Pubmed ID: 30219541 Disruption of Mesoderm Formation During Cardiac Differentiation Due to Developmental Exposure to 13-cis-retinoic Acid Scientific Reports. 08, 2018 | Pubmed ID: 30154523 Telomere Shortening is a Hallmark of Genetic Cardiomyopathies Proceedings of the National Academy of Sciences of the United States of America. 09, 2018 | Pubmed ID: 30150400 Disease Modelling and Drug Discovery for Hypertrophic Cardiomyopathy Using Pluripotent Stem Cells: How Far Have We Come? European Heart Journal. 11, 2018 | Pubmed ID: 30010924 Large-Scale Single-Cell RNA-Seq Reveals Molecular Signatures of Heterogeneous Populations of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells Circulation Research. Aug, 2018 | Pubmed ID: 29986945 Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes As Models for Cardiac Channelopathies: A Primer for Non-Electrophysiologists Circulation Research. 07, 2018 | Pubmed ID: 29976690 Determining the Pathogenicity of a Genomic Variant of Uncertain Significance Using CRISPR/Cas9 and Human-Induced Pluripotent Stem Cells Circulation. 12, 2018 | Pubmed ID: 29914921 Effects of Repetitive Transendocardial CD34 Cell Transplantation in Patients With Nonischemic Dilated Cardiomyopathy Circulation Research. 07, 2018 | Pubmed ID: 29880546 Systemic Upregulation of IL-10 (Interleukin-10) Using a Nonimmunogenic Vector Reduces Growth and Rate of Dissecting Abdominal Aortic Aneurysm Arteriosclerosis, Thrombosis, and Vascular Biology. 08, 2018 | Pubmed ID: 29880489 Prolonged Survival of Transplanted Stem Cells After Ischaemic Injury Via the Slow Release of Pro-survival Peptides from a Collagen Matrix Nature Biomedical Engineering. Feb, 2018 | Pubmed ID: 29721363 Cross-Site Reliability of Human Induced Pluripotent Stem Cell-derived Cardiomyocyte Based Safety Assays Using Microelectrode Arrays: Results from a Blinded CiPA Pilot Study Toxicological Sciences : an Official Journal of the Society of Toxicology. 08, 2018 | Pubmed ID: 29718449 Stage-specific Effects of Bioactive Lipids on Human IPSC Cardiac Differentiation and Cardiomyocyte Proliferation Scientific Reports. 04, 2018 | Pubmed ID: 29700394 Omics, Big Data, and Precision Medicine in Cardiovascular Sciences Circulation Research. 04, 2018 | Pubmed ID: 29700063 Pluripotent Stem Cell-Derived Cardiomyocytes As a Platform for Cell Therapy Applications: Progress and Hurdles for Clinical Translation Molecular Therapy : the Journal of the American Society of Gene Therapy. 07, 2018 | Pubmed ID: 29699941 Truncating Variants in NAA15 Are Associated with Variable Levels of Intellectual Disability, Autism Spectrum Disorder, and Congenital Anomalies American Journal of Human Genetics. 05, 2018 | Pubmed ID: 29656860 Dyslipidaemia: In Vivo Genome Editing of ANGPTL3: a Therapy for Atherosclerosis? Nature Reviews. Cardiology. May, 2018 | Pubmed ID: 29618844 Applications of Genetically Engineered Human Pluripotent Stem Cell Reporters in Cardiac Stem Cell Biology Current Opinion in Biotechnology. 08, 2018 | Pubmed ID: 29579626 Induced Pluripotent Stem Cells As a Biopharmaceutical Factory for Extracellular Vesicles European Heart Journal. 05, 2018 | Pubmed ID: 29547885 Modeling Human Diseases with Induced Pluripotent Stem Cells: from 2D to 3D and Beyond Development (Cambridge, England). 03, 2018 | Pubmed ID: 29519889 SETD7 Drives Cardiac Lineage Commitment Through Stage-Specific Transcriptional Activation Cell Stem Cell. 03, 2018 | Pubmed ID: 29499155 Autologous IPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo Cell Stem Cell. 04, 2018 | Pubmed ID: 29456158 Radiolabeled Duramycin: Promising Translational Imaging of Myocardial Apoptosis JACC. Cardiovascular Imaging. 12, 2018 | Pubmed ID: 29454760 Mining Exosomal MicroRNAs from Human-Induced Pluripotent Stem Cells-Derived Cardiomyocytes for Cardiac Regeneration Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29435928 Comparison of Non-human Primate Versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction Stem Cell Reports. 02, 2018 | Pubmed ID: 29398480 Endothelial Deletion of Ino80 Disrupts Coronary Angiogenesis and Causes Congenital Heart Disease Nature Communications. 01, 2018 | Pubmed ID: 29371594 Global Overview of the Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes (TACTICS) Recommendations: A Comprehensive Series of Challenges and Priorities of Cardiovascular Regenerative Medicine Circulation Research. 01, 2018 | Pubmed ID: 29348246 Cardiac Cell Cycle Activation As a Strategy to Improve IPSC-Derived Cardiomyocyte Therapy Circulation Research. 01, 2018 | Pubmed ID: 29301838 Human Induced Pluripotent Stem Cell (hiPSC)-Derived Cells to Assess Drug Cardiotoxicity: Opportunities and Problems Annual Review of Pharmacology and Toxicology. 01, 2018 | Pubmed ID: 28992430 Incremental Value of Right Heart Metrics and Exercise Performance to Well-validated Risk Scores in Dilated Cardiomyopathy European Heart Journal Cardiovascular Imaging. 08, 2018 | Pubmed ID: 28977353 Transcriptomic and Epigenomic Differences in Human Induced Pluripotent Stem Cells Generated from Six Reprogramming Methods Nature Biomedical Engineering. Oct, 2017 | Pubmed ID: 30263871 Simply Derived Epicardial Cells Nature Biomedical Engineering. 2017 | Pubmed ID: 29354320 GDF-15 (Growth Differentiation Factor 15) Is Associated With Lack of Ventricular Recovery and Mortality After Transcatheter Aortic Valve Replacement Circulation. Cardiovascular Interventions. Dec, 2017 | Pubmed ID: 29222133 Molecular and Functional Resemblance of Differentiated Cells Derived from Isogenic Human IPSCs and SCNT-derived ESCs Proceedings of the National Academy of Sciences of the United States of America. 12, 2017 | Pubmed ID: 29203658 Towards Cardio-Precision Medicine European Heart Journal. 04, 2017 | Pubmed ID: 29121213 Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells Circulation Research. Nov, 2017 | Pubmed ID: 29030344 Multiscale Technologies for Treatment of Ischemic Cardiomyopathy Nature Nanotechnology. 09, 2017 | Pubmed ID: 28875984 Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics Cell Reports. Aug, 2017 | Pubmed ID: 28834758 Combining HiPSCs and Human Genetics: Major Applications in Drug Development Cell Stem Cell. 08, 2017 | Pubmed ID: 28777942 Navigating the Future of Cardiovascular Drug Development-Leveraging Novel Approaches to Drive Innovation and Drug Discovery: Summary of Findings from the Novel Cardiovascular Therapeutics Conference Cardiovascular Drugs and Therapy. Aug, 2017 | Pubmed ID: 28735360 Comparison of Non-Coding RNAs in Exosomes and Functional Efficacy of Human Embryonic Stem Cell- Versus Induced Pluripotent Stem Cell-Derived Cardiomyocytes Stem Cells (Dayton, Ohio). 10, 2017 | Pubmed ID: 28710827 Genome-Wide Temporal Profiling of Transcriptome and Open Chromatin of Early Cardiomyocyte Differentiation Derived From HiPSCs and HESCs Circulation Research. Aug, 2017 | Pubmed ID: 28663367 Autoantibody Profiling on a Plasmonic Nano-gold Chip for the Early Detection of Hypertensive Heart Disease Proceedings of the National Academy of Sciences of the United States of America. 07, 2017 | Pubmed ID: 28630342 Patient-Specific Induced Pluripotent Stem Cell-Based Disease Model for Pathogenesis Studies and Clinical Pharmacotherapy Circulation. Arrhythmia and Electrophysiology. 06, 2017 | Pubmed ID: 28630175 Brief Report: External Beam Radiation Therapy for the Treatment of Human Pluripotent Stem Cell-Derived Teratomas Stem Cells (Dayton, Ohio). 08, 2017 | Pubmed ID: 28600830 Global Position Paper on Cardiovascular Regenerative Medicine European Heart Journal. 09, 2017 | Pubmed ID: 28575280 Specific Imaging of Bacterial Infection Using 6″-F-Fluoromaltotriose: A Second-Generation PET Tracer Targeting the Maltodextrin Transporter in Bacteria Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 10, 2017 | Pubmed ID: 28490473 3-Dimensionally Printed, Native-Like Scaffolds for Myocardial Tissue Engineering Circulation Research. 04, 2017 | Pubmed ID: 28408446 Contractile Force Generation by 3D HiPSC-derived Cardiac Tissues is Enhanced by Rapid Establishment of Cellular Interconnection in Matrix with Muscle-mimicking Stiffness Biomaterials. 07, 2017 | Pubmed ID: 28384492 Bioacoustic-enabled Patterning of Human IPSC-derived Cardiomyocytes into 3D Cardiac Tissue Biomaterials. 07, 2017 | Pubmed ID: 28376365 Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons Scientific Reports. 03, 2017 | Pubmed ID: 28327614 Genome Editing in Cardiovascular Biology Circulation Research. 03, 2017 | Pubmed ID: 28254802 A Comprehensive TALEN-Based Knockout Library for Generating Human-Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases Circulation Research. May, 2017 | Pubmed ID: 28246128 Nondestructive Nanostraw Intracellular Sampling for Longitudinal Cell Monitoring Proceedings of the National Academy of Sciences of the United States of America. 03, 2017 | Pubmed ID: 28223521 High-throughput Screening of Tyrosine Kinase Inhibitor Cardiotoxicity with Human Induced Pluripotent Stem Cells Science Translational Medicine. 02, 2017 | Pubmed ID: 28202772 Cardiac Subtype Characterization Using All-optical Action Potential Imaging European Heart Journal. 01, 2017 | Pubmed ID: 28182229 Defined Engineered Human Myocardium With Advanced Maturation for Applications in Heart Failure Modeling and Repair Circulation. May, 2017 | Pubmed ID: 28167635 Patient-Specific IPSC-Derived Endothelial Cells Uncover Pathways That Protect Against Pulmonary Hypertension in BMPR2 Mutation Carriers Cell Stem Cell. 04, 2017 | Pubmed ID: 28017794 Efficient Genome Editing in Induced Pluripotent Stem Cells with Engineered Nucleases In Vitro Methods in Molecular Biology (Clifton, N.J.). 2017 | Pubmed ID: 27910041 Induced Pluripotent Stem Cell Model of Pulmonary Arterial Hypertension Reveals Novel Gene Expression and Patient Specificity American Journal of Respiratory and Critical Care Medicine. 04, 2017 | Pubmed ID: 27779452 Challenging the Complementarity of Different Metrics of Left Atrial Function: Insight from a Cardiomyopathy-based Study European Heart Journal Cardiovascular Imaging. Oct, 2017 | Pubmed ID: 27638850 21st Century Cardio-Oncology: Identifying Cardiac Safety Signals in the Era of Personalized Medicine JACC. Basic to Translational Science. Aug, 2016 | Pubmed ID: 28713868 Patient-Specific and Genome-Edited Induced Pluripotent Stem Cell-Derived Cardiomyocytes Elucidate Single-Cell Phenotype of Brugada Syndrome Journal of the American College of Cardiology. 11, 2016 | Pubmed ID: 27810048 Telomere Shortening and Metabolic Compromise Underlie Dystrophic Cardiomyopathy Proceedings of the National Academy of Sciences of the United States of America. 11, 2016 | Pubmed ID: 27799523 Defective Signaling in the JAK-STAT Pathway Tracks with Chronic Inflammation and Cardiovascular Risk in Aging Humans Cell Systems. 10, 2016 | Pubmed ID: 27746093 IPSC-derived Cardiomyocytes Reveal Abnormal TGF-β Signalling in Left Ventricular Non-compaction Cardiomyopathy Nature Cell Biology. 10, 2016 | Pubmed ID: 27642787 Potential Strategies to Address the Major Clinical Barriers Facing Stem Cell Regenerative Therapy for Cardiovascular Disease: A Review JAMA Cardiology. 11, 2016 | Pubmed ID: 27579998 Transcriptome Profiling of Patient-Specific Human IPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses In Vitro Cell Stem Cell. 09, 2016 | Pubmed ID: 27545504 Alternative Approaches to Generating Cardiomyocytes Are Under Development Nature Reviews. Cardiology. 10, 2016 | Pubmed ID: 27538813 Effects of Cellular Origin on Differentiation of Human Induced Pluripotent Stem Cell-derived Endothelial Cells JCI Insight. 06, 2016 | Pubmed ID: 27398408 Allogeneic Mesenchymal Stromal Cells Overexpressing Mutant Human Hypoxia-Inducible Factor 1-α (HIF1-α) in an Ovine Model of Acute Myocardial Infarction Journal of the American Heart Association. 07, 2016 | Pubmed ID: 27385426 Finding Expandable Induced Cardiovascular Progenitor Cells Circulation Research. 06, 2016 | Pubmed ID: 27340267 Human Induced Pluripotent Stem Cells As a Platform for Personalized and Precision Cardiovascular Medicine Physiological Reviews. 07, 2016 | Pubmed ID: 27335446 Distilling Complexity to Advance Cardiac Tissue Engineering Science Translational Medicine. Jun, 2016 | Pubmed ID: 27280684 DNA Damage-associated Biomarkers in Studying Individual Sensitivity to Low-dose Radiation from Cardiovascular Imaging European Heart Journal. 10, 2016 | Pubmed ID: 27272147 Translation of Human-Induced Pluripotent Stem Cells: From Clinical Trial in a Dish to Precision Medicine Journal of the American College of Cardiology. May, 2016 | Pubmed ID: 27151349 A Tension-Based Model Distinguishes Hypertrophic Versus Dilated Cardiomyopathy Cell. May, 2016 | Pubmed ID: 27114035 Emerging Research Directions in Adult Congenital Heart Disease: A Report From an NHLBI/ACHA Working Group Journal of the American College of Cardiology. Apr, 2016 | Pubmed ID: 27102511 Human Induced Pluripotent Stem Cell-derived Cardiomyocytes Recapitulate the Predilection of Breast Cancer Patients to Doxorubicin-induced Cardiotoxicity Nature Medicine. 05, 2016 | Pubmed ID: 27089514 Fibrosis of the Neonatal Mouse Heart After Cryoinjury Is Accompanied by Wnt Signaling Activation and Epicardial-to-Mesenchymal Transition Journal of the American Heart Association. Mar, 2016 | Pubmed ID: 27068625 Efficacy of CD34+ Stem Cell Therapy in Nonischemic Dilated Cardiomyopathy Is Absent in Patients With Diabetes but Preserved in Patients With Insulin Resistance Stem Cells Translational Medicine. May, 2016 | Pubmed ID: 27025690 Human-induced Pluripotent Stem Cell Approaches to Model Inborn and Acquired Metabolic Heart Diseases Current Opinion in Cardiology. May, 2016 | Pubmed ID: 27022891 Induced Pluripotent Stem Cells: at the Heart of Cardiovascular Precision Medicine Nature Reviews. Cardiology. 06, 2016 | Pubmed ID: 27009425 Short Hairpin RNA Silencing of PHD-2 Improves Neovascularization and Functional Outcomes in Diabetic Wounds and Ischemic Limbs PloS One. 2016 | Pubmed ID: 26967994 Stem Cell Reprogramming: A 3D Boost Nature Materials. Mar, 2016 | Pubmed ID: 26906959 Comparison of Magnetic Resonance Imaging and Serum Biomarkers for Detection of Human Pluripotent Stem Cell-Derived Teratomas Stem Cell Reports. Feb, 2016 | Pubmed ID: 26777057 Genetic and Epigenetic Regulation of Human Cardiac Reprogramming and Differentiation in Regenerative Medicine Annual Review of Genetics. 2015 | Pubmed ID: 26631515 Chemically Defined Culture and Cardiomyocyte Differentiation of Human Pluripotent Stem Cells Current Protocols in Human Genetics. Oct, 2015 | Pubmed ID: 26439715 Matrigel Mattress: A Method for the Generation of Single Contracting Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Circulation Research. Dec, 2015 | Pubmed ID: 26429802 Microfluidic Single-Cell Analysis of Transplanted Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes After Acute Myocardial Infarction Circulation. Aug, 2015 | Pubmed ID: 26304668 Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model Circulation Research. Sep, 2015 | Pubmed ID: 26291556 Generation of IPSCs As a Pooled Culture Using Magnetic Activated Cell Sorting of Newly Reprogrammed Cells PloS One. 2015 | Pubmed ID: 26281015 Manganese-Enhanced Magnetic Resonance Imaging Enables In Vivo Confirmation of Peri-Infarct Restoration Following Stem Cell Therapy in a Porcine Ischemia-Reperfusion Model Journal of the American Heart Association. Jul, 2015 | Pubmed ID: 26215972 Assessment of the Radiation Effects Of Cardiac CT Angiography Using Protein and Genetic Biomarkers JACC. Cardiovascular Imaging. Aug, 2015 | Pubmed ID: 26210695 Hurdles to Clinical Translation of Human Induced Pluripotent Stem Cells The Journal of Clinical Investigation. Jul, 2015 | Pubmed ID: 26132109 Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an IPSC Model of Dilated Cardiomyopathy Cell Stem Cell. Jul, 2015 | Pubmed ID: 26095046 Human Induced Pluripotent Stem Cell-derived Cardiomyocytes: Insights into Molecular, Cellular, and Functional Phenotypes Circulation Research. Jun, 2015 | Pubmed ID: 26089365 Exosomes As Potential Alternatives to Stem Cell Therapy in Mediating Cardiac Regeneration Circulation Research. Jun, 2015 | Pubmed ID: 26089361 Finding the Rhythm of Sudden Cardiac Death: New Opportunities Using Induced Pluripotent Stem Cell-derived Cardiomyocytes Circulation Research. Jun, 2015 | Pubmed ID: 26044252 Extracellular Matrix Can Recover the Downregulation of Adhesion Molecules After Cell Detachment and Enhance Endothelial Cell Engraftment Scientific Reports. Jun, 2015 | Pubmed ID: 26039874 RNAseq Reveals a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension American Journal of Respiratory and Critical Care Medicine. Jun, 2015 | Pubmed ID: 26030479 Comparable Calcium Handling of Human IPSC-derived Cardiomyocytes Generated by Multiple Laboratories Journal of Molecular and Cellular Cardiology. Aug, 2015 | Pubmed ID: 25982839 Correction of Human Phospholamban R14del Mutation Associated with Cardiomyopathy Using Targeted Nucleases and Combination Therapy Nature Communications. 2015 | Pubmed ID: 25923014 MicroRNA-mediated Regulation of Differentiation and Trans-differentiation in Stem Cells Advanced Drug Delivery Reviews. Jul, 2015 | Pubmed ID: 25887992 Cardiovascular Molecular Imaging: Expanding the Paradigms and Parameters Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. Jun, 2015 | Pubmed ID: 25809082 Enabling Consistency in Pluripotent Stem Cell-derived Products for Research and Development and Clinical Applications Through Material Standards Stem Cells Translational Medicine. Mar, 2015 | Pubmed ID: 25650438 Variable Activation of the DNA Damage Response Pathways in Patients Undergoing Single-photon Emission Computed Tomography Myocardial Perfusion Imaging Circulation. Cardiovascular Imaging. Feb, 2015 | Pubmed ID: 25609688 [Pyr1]-Apelin-13 Delivery Via Nano-liposomal Encapsulation Attenuates Pressure Overload-induced Cardiac Dysfunction Biomaterials. Jan, 2015 | Pubmed ID: 25443792 Multi-cellular Interactions Sustain Long-term Contractility of Human Pluripotent Stem Cell-derived Cardiomyocytes American Journal of Translational Research. 2014 | Pubmed ID: 25628783 Pravastatin Reverses Obesity-induced Dysfunction of Induced Pluripotent Stem Cell-derived Endothelial Cells Via a Nitric Oxide-dependent Mechanism European Heart Journal. Nov, 2014 | Pubmed ID: 25368203 Characterization of the Molecular Mechanisms Underlying Increased Ischemic Damage in the Aldehyde Dehydrogenase 2 Genetic Polymorphism Using a Human Induced Pluripotent Stem Cell Model System Science Translational Medicine. Sep, 2014 | Pubmed ID: 25253673 On-line Visualization of Ischemic Burden During Repetitive Ischemia/reperfusion JACC. Cardiovascular Imaging. Sep, 2014 | Pubmed ID: 25212802 Cardiac Tissue Slice Transplantation As a Model to Assess Tissue-engineered Graft Thickness, Survival, and Function Circulation. Sep, 2014 | Pubmed ID: 25200059 Cross Talk of Combined Gene and Cell Therapy in Ischemic Heart Disease: Role of Exosomal MicroRNA Transfer Circulation. Sep, 2014 | Pubmed ID: 25200057 Effects of Transendocardial CD34+ Cell Transplantation in Patients With Ischemic Cardiomyopathy Circulation. Cardiovascular Interventions. Aug, 2014 | Pubmed ID: 25097199 Genome Editing of Isogenic Human Induced Pluripotent Stem Cells Recapitulates Long QT Phenotype for Drug Testing Journal of the American College of Cardiology. Aug, 2014 | Pubmed ID: 25082577 Effect of Human Donor Cell Source on Differentiation and Function of Cardiac Induced Pluripotent Stem Cells Journal of the American College of Cardiology. Aug, 2014 | Pubmed ID: 25082575 Second Generation Codon Optimized Minicircle (CoMiC) for Nonviral Reprogramming of Human Adult Fibroblasts Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 25070322 A Human Pluripotent Stem Cell Surface N-glycoproteome Resource Reveals Markers, Extracellular Epitopes, and Drug Targets Stem Cell Reports. Jul, 2014 | Pubmed ID: 25068131 The Effects of Levosimendan on Renal Function Early After Heart Transplantation: Results from a Pilot Randomized Trial Clinical Transplantation. Jul, 2014 | Pubmed ID: 25053182 Human Induced Pluripotent Stem Cell-derived Cardiomyocytes As an in Vitro Model for Coxsackievirus B3-induced Myocarditis and Antiviral Drug Screening Platform Circulation Research. Aug, 2014 | Pubmed ID: 25015077 Chemically Defined Generation of Human Cardiomyocytes Nature Methods. Aug, 2014 | Pubmed ID: 24930130 Identification of a New Modulator of the Intercalated Disc in a Zebrafish Model of Arrhythmogenic Cardiomyopathy Science Translational Medicine. Jun, 2014 | Pubmed ID: 24920660 Human Stem Cells for Modeling Heart Disease and for Drug Discovery Science Translational Medicine. Jun, 2014 | Pubmed ID: 24898747 Transplanted Terminally Differentiated Induced Pluripotent Stem Cells Are Accepted by Immune Mechanisms Similar to Self-tolerance Nature Communications. 2014 | Pubmed ID: 24875164 Rapid and Efficient Conversion of Integration-free Human Induced Pluripotent Stem Cells to GMP-grade Culture Conditions PloS One. 2014 | Pubmed ID: 24718618 Stem Cell Imaging: from Bench to Bedside Cell Stem Cell. Apr, 2014 | Pubmed ID: 24702995 Modeling Inherited Cardiac Disorders Circulation Journal : Official Journal of the Japanese Circulation Society. 2014 | Pubmed ID: 24632794 Stem Cells and Cardiovascular Drug Development--reply JAMA. Mar, 2014 | Pubmed ID: 24618976 Human-induced Pluripotent Stem Cell Models of Inherited Cardiomyopathies Current Opinion in Cardiology. May, 2014 | Pubmed ID: 24576884 Construction and Validation of Nano Gold Tripods for Molecular Imaging of Living Subjects Journal of the American Chemical Society. Mar, 2014 | Pubmed ID: 24495038 The Role of Hath6, a Newly Identified Shear-stress-responsive Transcription Factor, in Endothelial Cell Differentiation and Function Journal of Cell Science. Apr, 2014 | Pubmed ID: 24463812 Tracking Gene and Cell Fate for Therapeutic Gain Nature Materials. Feb, 2014 | Pubmed ID: 24452344 Relationship Between Echocardiographic and Magnetic Resonance Derived Measures of Right Ventricular Size and Function in Patients with Pulmonary Hypertension Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. Apr, 2014 | Pubmed ID: 24444659 Cardiac Stem Cell Biology: Glimpse of the Past, Present, and Future Circulation Research. Jan, 2014 | Pubmed ID: 24385505 Predicting the Future with Stem Cells Circulation. Jan, 2014 | Pubmed ID: 24249719 Short Hairpin RNA Gene Silencing of Prolyl Hydroxylase-2 with a Minicircle Vector Improves Neovascularization of Hindlimb Ischemia Human Gene Therapy. Jan, 2014 | Pubmed ID: 24090375 Induced Pluripotent Stem Cell-derived Cardiomyocytes for Cardiovascular Disease Modeling and Drug Screening Stem Cell Research & Therapy. 2013 | Pubmed ID: 24476344 Cardiovascular Molecular Imaging As a Tool to Study Biology Theranostics. 2013 | Pubmed ID: 24396501 American Journal of Nuclear Medicine and Molecular Imaging: Editorial Board (2014) E-Century Publishing Corporation American Journal of Nuclear Medicine and Molecular Imaging. 2013 | Pubmed ID: 24380049 Imaging Cardiac Stem Cell Transplantation Using Radionuclide Labeling Techniques: Clinical Applications and Future Directions Methodist DeBakey Cardiovascular Journal. Oct-Dec, 2013 | Pubmed ID: 24298314 Patient-specific Stem Cells and Cardiovascular Drug Discovery JAMA. Nov, 2013 | Pubmed ID: 24240927 Costimulation-adhesion Blockade is Superior to Cyclosporine A and Prednisone Immunosuppressive Therapy for Preventing Rejection of Differentiated Human Embryonic Stem Cells Following Transplantation Stem Cells (Dayton, Ohio). Nov, 2013 | Pubmed ID: 24038578 Comparison of Transendocardial and Intracoronary CD34+ Cell Transplantation in Patients with Nonischemic Dilated Cardiomyopathy Circulation. Sep, 2013 | Pubmed ID: 24030420 Screening Drug-induced Arrhythmia [corrected] Using Human Induced Pluripotent Stem Cell-derived Cardiomyocytes and Low-impedance Microelectrode Arrays Circulation. Sep, 2013 | Pubmed ID: 24030418 A Transgenic Tri-modality Reporter Mouse PloS One. 2013 | Pubmed ID: 23951359 Cortical Bone-derived Stem Cells: a Novel Class of Cells for Myocardial Protection Circulation Research. Aug, 2013 | Pubmed ID: 23948579 Noninvasive Imaging of Hypoxia-inducible Factor-1α Gene Therapy for Myocardial Ischemia Human Gene Therapy Methods. Oct, 2013 | Pubmed ID: 23937265 Tumorigenicity As a Clinical Hurdle for Pluripotent Stem Cell Therapies Nature Medicine. Aug, 2013 | Pubmed ID: 23921754 Clonal Precursor of Bone, Cartilage, and Hematopoietic Niche Stromal Cells Proceedings of the National Academy of Sciences of the United States of America. Jul, 2013 | Pubmed ID: 23858471 Development of Poly(β-amino Ester)-Based Biodegradable Nanoparticles for Nonviral Delivery of Minicircle DNA ACS Nano. Aug, 2013 | Pubmed ID: 23837668 Global Epigenomic Reconfiguration During Mammalian Brain Development Science (New York, N.Y.). Aug, 2013 | Pubmed ID: 23828890 Generation of Human IPSCs from Human Peripheral Blood Mononuclear Cells Using Non-integrative Sendai Virus in Chemically Defined Conditions Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23807788 Overview of High Throughput Sequencing Technologies to Elucidate Molecular Pathways in Cardiovascular Diseases Circulation Research. Jun, 2013 | Pubmed ID: 23743227 Induced Pluripotency of Human Prostatic Epithelial Cells PloS One. 2013 | Pubmed ID: 23717621 Stem Cell Isolation: Differential Stickiness Nature Materials. Jun, 2013 | Pubmed ID: 23695740 The Role of SIRT6 Protein in Aging and Reprogramming of Human Induced Pluripotent Stem Cells The Journal of Biological Chemistry. Jun, 2013 | Pubmed ID: 23653361 Molecular Imaging: the Key to Advancing Cardiac Stem Cell Therapy Trends in Cardiovascular Medicine. Aug, 2013 | Pubmed ID: 23561794 Drug Screening Using a Library of Human Induced Pluripotent Stem Cell-derived Cardiomyocytes Reveals Disease-specific Patterns of Cardiotoxicity Circulation. Apr, 2013 | Pubmed ID: 23519760 Enhanced Aβ(1-40) Production in Endothelial Cells Stimulated with Fibrillar Aβ(1-42) PloS One. 2013 | Pubmed ID: 23505467 Dissecting the Molecular Relationship Among Various Cardiogenic Progenitor Cells Circulation Research. Apr, 2013 | Pubmed ID: 23463815 Immunogenicity of Pluripotent Stem Cells and Their Derivatives Circulation Research. Feb, 2013 | Pubmed ID: 23371903 異常なカルシウム処理プロパティ患者固有の誘導多能性幹細胞の家族性肥大型心筋症病態の根底にあります。 Cell Stem Cell. Jan, 2013 | Pubmed ID: 23290139 Advances in Nanotechnology for the Management of Coronary Artery Disease Trends in Cardiovascular Medicine. Feb, 2013 | Pubmed ID: 23245913 A Review of Human Pluripotent Stem Cell-derived Cardiomyocytes for High-throughput Drug Discovery, Cardiotoxicity Screening, and Publication Standards Journal of Cardiovascular Translational Research. Feb, 2013 | Pubmed ID: 23229562 Loss of CDKN2B Promotes P53-dependent Smooth Muscle Cell Apoptosis and Aneurysm Formation Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2013 | Pubmed ID: 23162013 MicroRNA-302 Increases Reprogramming Efficiency Via Repression of NR2F2 Stem Cells (Dayton, Ohio). Feb, 2013 | Pubmed ID: 23136034 MTORC1 and MTORC2 Play Different Roles in the Functional Survival of Transplanted Adipose-derived Stromal Cells in Hind Limb Ischemic Mice Via Regulating Inflammation in Vivo Stem Cells (Dayton, Ohio). Jan, 2013 | Pubmed ID: 23081858 Effective Delivery of Stem Cells Using an Extracellular Matrix Patch Results in Increased Cell Survival and Proliferation and Reduced Scarring in Skin Wound Healing Tissue Engineering. Part A. Mar, 2013 | Pubmed ID: 23072446 Human Embryonic Stem Cell-derived Endothelial Cells As Cellular Delivery Vehicles for Treatment of Metastatic Breast Cancer Cell Transplantation. 2013 | Pubmed ID: 23067802 Effects of Intracoronary CD34+ Stem Cell Transplantation in Nonischemic Dilated Cardiomyopathy Patients: 5-year Follow-up Circulation Research. Jan, 2013 | Pubmed ID: 23065358 Imaging Neural Stem Cell Graft-induced Structural Repair in Stroke Cell Transplantation. 2013 | Pubmed ID: 23044338 MicroRNA Expression Profiling of Human-induced Pluripotent and Embryonic Stem Cells Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23007513 Sacrificial Layer Technique for Axial Force Post Assay of Immature Cardiomyocytes Biomedical Microdevices. Feb, 2013 | Pubmed ID: 23007494 The Right Heart in Congenital Heart Disease, Mechanisms and Recent Advances Journal of Clinical & Experimental Cardiology. Jun, 2012 | Pubmed ID: 23483726 Pluripotent Stem Cells: Immune to the Immune System? Science Translational Medicine. Dec, 2012 | Pubmed ID: 23241742 In Vivo では分化多能性幹細胞骨格の再生のための監督。 Proceedings of the National Academy of Sciences of the United States of America. Nov, 2012 | Pubmed ID: 23169671 American Journal of Nuclear Medicine and Molecular Imaging: Editorial Board (2012) E-Century Publishing Corporation American Journal of Nuclear Medicine and Molecular Imaging. 2012 | Pubmed ID: 23145366 Returns of the Living Dead: Therapeutic Action of Irradiated and Mitotically Inactivated Embryonic Stem Cells Circulation Research. Oct, 2012 | Pubmed ID: 23104873 Biomaterial Applications in Cardiovascular Tissue Repair And regeneration Expert Review of Cardiovascular Therapy. Aug, 2012 | Pubmed ID: 23030293 Pushing the Reset Button: Chemical-induced Conversion of Amniotic Fluid Stem Cells into a Pluripotent State Molecular Therapy : the Journal of the American Society of Gene Therapy. Oct, 2012 | Pubmed ID: 23023056 Transient, Inducible, Placenta-specific Gene Expression in Mice Endocrinology. Nov, 2012 | Pubmed ID: 23011919 Genome Editing of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells with Zinc Finger Nucleases for Cellular Imaging Circulation Research. Dec, 2012 | Pubmed ID: 22967807 Safe Genetic Modification of Cardiac Stem Cells Using a Site-specific Integration Technique Circulation. Sep, 2012 | Pubmed ID: 22965984 Multimodality Imaging Evaluation of Functional and Clinical Benefits of Percutaneous Coronary Intervention in Patients with Chronic Total Occlusion Lesion Theranostics. 2012 | Pubmed ID: 22916078 In Vivo, Ex Vivo, and in Vitro Studies on Apelin's Effect on Myocardial Glucose Uptake Peptides. Oct, 2012 | Pubmed ID: 22906703 Human Cardiac Progenitor Cells Engineered with Pim-I Kinase Enhance Myocardial Repair Journal of the American College of Cardiology. Oct, 2012 | Pubmed ID: 22841153 マイクロ流体単一細胞解析ブタ誘導多能性幹細胞由来内皮細胞がパラクリン活性化による心筋機能を向上させることを示しています。 Circulation Research. Sep, 2012 | Pubmed ID: 22821929 Atomic Force Mechanobiology of Pluripotent Stem Cell-derived Cardiomyocytes PloS One. 2012 | Pubmed ID: 22624048 ナチュラル キラー細胞の磁性ナノ粒子を使用してターゲット腫瘍部位への操作。 Biomaterials. Aug, 2012 | Pubmed ID: 22575830 Early Stem Cell Engraftment Predicts Late Cardiac Functional Recovery: Preclinical Insights from Molecular Imaging Circulation. Cardiovascular Imaging. May, 2012 | Pubmed ID: 22565608 In Vivo Molecular Imaging of Murine Embryonic Stem Cells Delivered to a Burn Wound Surface Via Integra® Scaffolding Journal of Burn Care & Research : Official Publication of the American Burn Association. Mar-Apr, 2012 | Pubmed ID: 22540138 家族性拡張型心筋症モデルとしての患者固有の誘導多能性幹細胞。 Science Translational Medicine. Apr, 2012 | Pubmed ID: 22517884 Molecular Imaging of Stem Cells: Tracking Survival, Biodistribution, Tumorigenicity, and Immunogenicity Theranostics. 2012 | Pubmed ID: 22509197 CD44 Antibody-targeted Liposomal Nanoparticles for Molecular Imaging and Therapy of Hepatocellular Carcinoma Biomaterials. Jul, 2012 | Pubmed ID: 22494888 Microfluidic Single-cell Real-time PCR for Comparative Analysis of Gene Expression Patterns Nature Protocols. May, 2012 | Pubmed ID: 22481529 Dynamic MicroRNA Expression During the Transition from Right Ventricular Hypertrophy to Failure Physiological Genomics. May, 2012 | Pubmed ID: 22454450 疾病のモデリングと創薬スクリーニング·プラットフォームとして、誘導多能性幹細胞 Journal of Cardiovascular Pharmacology. Jan, 2012 | Pubmed ID: 22240913 マウス末梢動脈疾患における骨髄単核細胞の生存とホーミングの分子イメージング JACC. Cardiovascular Imaging. Jan, 2012 | Pubmed ID: 22239892 末梢動脈疾患の治療のためのイメージング幹細胞療法 Current Vascular Pharmacology. Jan, 2012 | Pubmed ID: 22239638 心血管系のフィットネスはɛ4キャリアにワーキングメモリ中に変更皮質グルコース代謝に関係している Alzheimer's & Dementia : the Journal of the Alzheimer's Association. Jan, 2012 | Pubmed ID: 22226798 De Novoの心筋細胞の産生：ヒト多能性幹細胞の分化およびダイレクトリプログラミング Cell Stem Cell. Jan, 2012 | Pubmed ID: 22226352 ヒト疾患研究のための前臨床モデルとしての大型動物誘導多能性幹細胞 Journal of Cellular and Molecular Medicine. Jan, 2012 | Pubmed ID: 22212700 インビボでの下垂体に比べて線条体のドーパミンD2受容体占有のケトコナゾール関連優遇増加：薬物トランスポーターの役割？ Journal of Clinical Psychopharmacology. Feb, 2012 | Pubmed ID: 22198458 虚血心筋に移植後の骨髄幹細胞のin Vivo機能と転写プロファイリングで Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2012 | Pubmed ID: 22034515 BMP-2阻害剤のノックダウンによる人間脂肪由来間質細胞の血管新生の増強 Plastic and Reconstructive Surgery. Jan, 2012 | Pubmed ID: 21915082 ヒト胚性幹細胞由来心筋細胞の心室の仕様および機能的成熟におけるマイクロRNA-1と-499の異なる役割 PloS One. 2011 | Pubmed ID: 22110643 心血管疾患や慢性炎症における血管内皮前駆細胞：バイオマーカーから治療剤 Biomarkers in Medicine. Dec, 2011 | Pubmed ID: 22103609 ノックダウンとカスタマイズされた足場の設計をNonintegratingと骨格修復にヒト脂肪由来幹細胞を強化 Stem Cells (Dayton, Ohio). Dec, 2011 | Pubmed ID: 21997852 イメージング：心筋幹細胞治療の臨床翻訳ガイ Circulation Research. Sep, 2011 | Pubmed ID: 21960727 非ウイルスMinicircle遺伝子治療とプロリルヒドロキシラーゼと因子を阻害する低酸素誘導因子のダブルノックダウンは、心筋梗塞後の幹細胞動員と血管新生を増強する Circulation. Sep, 2011 | Pubmed ID: 21911818 心臓前駆細胞移植の生着と機能を向上させるための新規microRNAのProsurvivalカクテル Circulation. Sep, 2011 | Pubmed ID: 21911815 プラスミドDNAを効率的に誘導多能性幹細胞を作成する部位特異的リコンビナーゼ戦略 Stem Cells (Dayton, Ohio). Nov, 2011 | Pubmed ID: 21898697 複雑な精神疾患症例における脳SPECTイメージング：エビデンスに基づく、十分に活用ツール The Open Neuroimaging Journal. 2011 | Pubmed ID: 21863144 ヒト多能性幹細胞におけるSSEA-5糖鎖に対する抗体は奇形腫を形成する細胞の除去を可能にします Nature Biotechnology. Sep, 2011 | Pubmed ID: 21841799 F18-フルオロデオキシグルコース陽電子放射断層撮影法とイメージングアテローム性動脈硬化症：どのような我々は、実際に見ている？ Journal of the American College of Cardiology. Aug, 2011 | Pubmed ID: 21798424 In Vitroおよびin Vivoで、マウスイヌ、及びヒト供給源から脂肪由来間質細胞の骨分化の違い Plastic and Reconstructive Surgery. Aug, 2011 | Pubmed ID: 21788829 Ex Vivoでの酸性プレコンディショニングは、骨髄Ckitを強化+細胞治療の可能性を増加させCXCR4発現を介して European Heart Journal. Jul, 2011 | Pubmed ID: 21784762 自家移植犬の誘導多能性幹細胞の臨床導出とイメージング The Journal of Biological Chemistry. Sep, 2011 | Pubmed ID: 21719696 トラッキング細胞運命と機能のin Vivo生物発光の American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2011 | Pubmed ID: 21666118 分化したヒト誘導多能性幹細胞とヒト胚性幹細胞の発がん性と腫瘍形成能を解剖 Cancer Research. Jul, 2011 | Pubmed ID: 21646469 生体内における胚性幹細胞の移行のイメージング Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21618086 外傷性脳損傷、薬物乱用のリハビリのための含意：元NFL選手の脳損傷を逆転させる Journal of Psychoactive Drugs. Jan-Mar, 2011 | Pubmed ID: 21615001 Report of the National Heart, Lung, and Blood Institute Working Group on the Translation of Cardiovascular Molecular Imaging Circulation. May, 2011 | Pubmed ID: 21576680 イメージング心臓幹細胞治療：ヒト臨床研究への翻訳 Journal of Cardiovascular Translational Research. Aug, 2011 | Pubmed ID: 21538182 心血管疾患のモデリングのための人間誘導多能性幹細胞の誘導 Circulation Research. Apr, 2011 | Pubmed ID: 21527744 ポリエチレンイミンポリマーハイブリッドをリンクされたペプチドを用いた初代ヒト細胞の効率的な遺伝子送達 Biomaterials. Jul, 2011 | Pubmed ID: 21477858 ヒト人工多能性胚性幹細胞の比較：友愛または一卵性双生児？ Molecular Therapy : the Journal of the American Society of Gene Therapy. Apr, 2011 | Pubmed ID: 21455209 画像検査からの放射線被ばく：増加がんのリスクはありますか？ Expert Review of Cardiovascular Therapy. Feb, 2011 | Pubmed ID: 21453214 短期的な免疫抑制は胚および誘導多能性幹細胞の生着を促進する Cell Stem Cell. Mar, 2011 | Pubmed ID: 21362570 生物発光レポーター遺伝子イメージングはヒト胚性幹細胞由来の奇形腫形成を特徴づける Journal of Cellular Biochemistry. Mar, 2011 | Pubmed ID: 21328457 単一細胞転写プロファイリングは、ヒューマン·誘導多能性幹細胞の不均一性を明らかに The Journal of Clinical Investigation. Mar, 2011 | Pubmed ID: 21317531 心臓血管分子イメージング：臨床の翻訳を中心に Circulation. Feb, 2011 | Pubmed ID: 21282520 ヒト人工多能性幹細胞と胚性幹細胞由来の血管内皮細胞の機能解析と発現プロファイリング Stem Cells and Development. Oct, 2011 | Pubmed ID: 21235328 非ウイルスMinicircle DNAベクターを用いた成人ヒト誘導多能性幹細胞の生成 Nature Protocols. 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Jun, 2008 | Pubmed ID: 18434620 PETを用いたラット心筋梗塞モデルにおけるVEGF受容体のイメージング Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Apr, 2008 | Pubmed ID: 18375924 臨床応用に向けて移動する豚の皮配信に続いてレポーター遺伝子イメージング Journal of the American College of Cardiology. Feb, 2008 | Pubmed ID: 18237691 レポーター遺伝子と生活課題におけるヒト胚性幹細胞および分化内皮細胞の追跡フェイト鉄粒子のラベルの比較 Stem Cells (Dayton, Ohio). Apr, 2008 | Pubmed ID: 18218820 うつ病患者の相対的なグルコース代謝の変化とハミルトンの症状改善格の剥奪のPET相関をスリープ Journal of Affective Disorders. Apr, 2008 | Pubmed ID: 18031825 郭清を伴う大動脈瘤と間違え大血管転位症の外科的に緩和さダブルインレット左心室 International Journal of Cardiology. Aug, 2008 | Pubmed ID: 17689761 幹細胞の生存性を向上させるための様々なBiomatricesのin Vivoイメージングと評価で Journal of Tissue Engineering and Regenerative Medicine. Nov-Dec, 2007 | Pubmed ID: 18163533 VEGFによる胚性幹細胞の遺伝子改変は、細胞の生存を強化し、心臓機能を改善する Cloning and Stem Cells. 2007 | Pubmed ID: 18154515 心臓幹細胞療法を追跡するためのイメージング技術との比較 Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 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Wu1,2,3 1Stanford Cardiovascular Institute, Stanford University School of Medicine, 2Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, 3Department of Radiology, Stanford University School of Medicine JoVE 64265 Medicine ヒトiPSC由来心筋細胞、心臓線維芽細胞、内皮細胞を用いた3次元心臓ミクロ組織アレイの作製 Dilip Thomas1, Hyeonyu Kim1, Nicole Lopez1, Joseph C. Wu1,2,3 1Stanford Cardiovascular Institute, Stanford University School of Medicine, 2Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, 3Department of Radiology, Stanford University School of Medicine JoVE 61879 Bioengineering フローサイトメトリーによる高効率心筋細胞へのヒト多能性幹細胞の分化と特性 Subarna Bhattacharya*1, Paul W. Burridge*2, Erin M. Kropp1, Sandra L. Chuppa1, Wai-Meng Kwok3, Joseph C. Wu2, Kenneth R. Boheler4,5, Rebekah L. Gundry1,6 1Department of Biochemistry, Medical College of Wisconsin, 2Stanford Cardiovascular Institute, Stanford University School of Medicine, 3Department of Anesthesiology, Medical College of Wisconsin, 4Stem Cell and Regenerative Medicine Consortium, LKS Faculty of Medicine, Hong Kong University, 5Division of Cardiology, Johns Hopkins University School of Medicine, 6Cardiovascular Research Center, Biotechnology and Bioengineering Center, Medical College of Wisconsin JoVE 52010 Biology in vitroおよびヒト胚性幹細胞のin vivoでの生物発光レポーター遺伝子イメージングの Kitchener Wilson1, Jin Yu1, Andrew Lee1, Joseph C. Wu1 1Departments of Radiology and Medicine (Cardiology), Stanford University School of Medicine JoVE 740 Biology
ヒト人工多能性幹細胞由来心筋細胞における微小電極アレイおよびパッチクランプ記録の技術的応用 Shane Rui Zhao1,2, Gema Mondéjar-Parreño1,2, Dong Li1,2, Mengcheng Shen1,2, Joseph C. Wu1,2,3 1Stanford Cardiovascular Institute, Stanford University School of Medicine, 2Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, 3Department of Radiology, Stanford University School of Medicine JoVE 64265 Medicine
ヒトiPSC由来心筋細胞、心臓線維芽細胞、内皮細胞を用いた3次元心臓ミクロ組織アレイの作製 Dilip Thomas1, Hyeonyu Kim1, Nicole Lopez1, Joseph C. Wu1,2,3 1Stanford Cardiovascular Institute, Stanford University School of Medicine, 2Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, 3Department of Radiology, Stanford University School of Medicine JoVE 61879 Bioengineering
フローサイトメトリーによる高効率心筋細胞へのヒト多能性幹細胞の分化と特性 Subarna Bhattacharya*1, Paul W. Burridge*2, Erin M. Kropp1, Sandra L. Chuppa1, Wai-Meng Kwok3, Joseph C. Wu2, Kenneth R. Boheler4,5, Rebekah L. Gundry1,6 1Department of Biochemistry, Medical College of Wisconsin, 2Stanford Cardiovascular Institute, Stanford University School of Medicine, 3Department of Anesthesiology, Medical College of Wisconsin, 4Stem Cell and Regenerative Medicine Consortium, LKS Faculty of Medicine, Hong Kong University, 5Division of Cardiology, Johns Hopkins University School of Medicine, 6Cardiovascular Research Center, Biotechnology and Bioengineering Center, Medical College of Wisconsin JoVE 52010 Biology
in vitroおよびヒト胚性幹細胞のin vivoでの生物発光レポーター遺伝子イメージングの Kitchener Wilson1, Jin Yu1, Andrew Lee1, Joseph C. Wu1 1Departments of Radiology and Medicine (Cardiology), Stanford University School of Medicine JoVE 740 Biology
