Other Publications (1)
Articles by Joseph Abbah in JoVE
Migratory Behavior of Cells Generated in Ganglionic Eminence Cultures Marcin Gierdalski*1, Thomas McFate*1, Joseph Abbah2, Sharon L. Juliano1,2 1Dept. of Anatomy, Physiology and Genetics, Uniformed Services University, 2Neuroscience Program, Uniformed Services University Time lapse imaging of 3D tissue culture allows studying migratory behavior of individual cells originating from ganglionic eminence in reaction to fractionated protein extract from cerebral cortex.
Other articles by Joseph Abbah on PubMed
Studies on the Use of Cassia Singueana in Malaria Ethnopharmacy Journal of Ethnopharmacology. Oct, 2003 | Pubmed ID: 12963153 Cassia singueana (Family: Fabaceae) is used in northern Nigeria for the treatment of acute malaria attack. We investigated the activities of the methanol extract of the root bark of this plant against rodent plasmodia infection, nociception, pyrexia and inflammation in mice and rats. The studies were carried out using acetic acid-induced writhing, hot plate algesia, rodent plasmodia (Plasmodium berghei) in mice; formalin test, yeast-induced pyrexia and egg-albumin-induced inflammation in rats. The results showed that the extract exhibited significant antinociceptive, antipyretic and antiplasmodial activity in all the models used. Phytochemical screening of the extract revealed the presence of phenols, saponins, tannins and some traces of anthraquinones. The LD50 of the extract was established to be 847+/-30 mg/kg, i.p. in mice. The observed pharmacological activities might be the scientific basis for the folkloric use of the plant in treating acute malaria attack. The study also paves way for the possible development of it, as a phytodrug against malaria.