Josephine Hoh

Publications

• 2016: A 'Mitochondria' Odyssey
  Trends in Molecular Medicine. Apr, 2016  |   Pubmed ID: 27151392
• Genetic Risk Score for Essential Hypertension and Risk of Preeclampsia
  American Journal of Hypertension. Jan, 2016  |   Pubmed ID: 26002928
• Generation and Characterization of Mice with a Conditional Null Allele of the HtrA4 Gene
  Molecular Medicine Reports. Nov, 2015  |   Pubmed ID: 26353049
• Loss of HtrA1-induced Attenuation of TGF-β Signaling in Fibroblasts Might Not Be the Main Mechanism of CARASIL Pathogenesis
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2015  |   Pubmed ID: 25770224
• Postnatal Overexpression of the Human ARMS2 Gene Does Not Induce Abnormalities in Retina and Choroid in Transgenic Mouse Models
  Investigative Ophthalmology & Visual Science. Feb, 2015  |   Pubmed ID: 25717153
• Genetic Predisposition to Dyslipidemia and Risk of Preeclampsia
  American Journal of Hypertension. Jul, 2015  |   Pubmed ID: 25523295
• Neural-specific Deletion of Htra2 Causes Cerebellar Neurodegeneration and Defective Processing of Mitochondrial OPA1
  PloS One. 2014  |   Pubmed ID: 25531304
• Protoporphyrins Enhance Oligomerization and Enzymatic Activity of HtrA1 Serine Protease
  PloS One. 2014  |   Pubmed ID: 25506911
• Scan Statistics in Human Gene Mapping
  American Journal of Human Genetics. Nov, 2012  |   Pubmed ID: 23122592
• Stage and Gene Specific Signatures Defined by Histones H3K4me2 and H3K27me3 Accompany Mammalian Retina Maturation in Vivo
  PloS One. 2012  |   Pubmed ID: 23056497
• Genome-wide Association Study Identifies a Maternal Copy-number Deletion in PSG11 Enriched Among Preeclampsia Patients
  BMC Pregnancy and Childbirth. 2012  |   Pubmed ID: 22748001
• Genetic Signatures of Exceptional Longevity in Humans
  PloS One. 2012  |   Pubmed ID: 22279548
• Disease Risk Prediction with Rare and Common Variants
  BMC Proceedings. 2011  |   Pubmed ID: 22373337
• A Comparison of Association Methods Correcting for Population Stratification in Case-control Studies
  Annals of Human Genetics. May, 2011  |   Pubmed ID: 21281271
• A Pilot Genome-wide Association Study Shows Genomic Variants Enriched in the Non-tumor Cells of Patients with Well-differentiated Neuroendocrine Tumors of the Ileum
  Endocrine-related Cancer. Feb, 2011  |   Pubmed ID: 21139019
• PDE11A Associations with Asthma: Results of a Genome-wide Association Scan
  The Journal of Allergy and Clinical Immunology. Oct, 2010  |   Pubmed ID: 20920776
• Common Variants Near CAV1 and CAV2 Are Associated with Primary Open-angle Glaucoma
  Nature Genetics. Oct, 2010  |   Pubmed ID: 20835238
• Association Between Reduced Copy-number at T-cell Receptor Gamma (TCRgamma) and Childhood Allergic Asthma: A Possible Role for Somatic Mosaicism
  Mutation Research. Aug, 2010  |   Pubmed ID: 20553737
• A Genome-wide Association Study on African-ancestry Populations for Asthma
  The Journal of Allergy and Clinical Immunology. Feb, 2010  |   Pubmed ID: 19910028
• Detecting Essential and Removable Interactions in Genome-wide Association Studies
  Statistics and Its Interface. Jan, 2009  |   Pubmed ID: 21165165
• Common Variants on Chromosome 2 and Risk of Primary Open-angle Glaucoma in the Afro-Caribbean Population of Barbados
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2009  |   Pubmed ID: 19805132
• CCR3: Shedding New Light on a Dark Problem?
  Journal of Molecular Cell Biology. Oct, 2009  |   Pubmed ID: 19684049
• Interaction Between the Serotonin Transporter Gene (5-HTTLPR), Stressful Life Events, and Risk of Depression: a Meta-analysis
  JAMA. Jun, 2009  |   Pubmed ID: 19531786
• Mitochondrial DNA Variants of Respiratory Complex I That Uniquely Characterize Haplogroup T2 Are Associated with Increased Risk of Age-related Macular Degeneration
  PloS One. 2009  |   Pubmed ID: 19434233
• Sequence Variants in HTRA1 and LOC387715/ARMS2 and Phenotype and Response to Photodynamic Therapy in Neovascular Age-related Macular Degeneration in Populations from Israel
  Molecular Vision. 2008  |   Pubmed ID: 19065273
• Joint Effects of Polymorphisms in the HTRA1, LOC387715/ARMS2, and CFH Genes on AMD in a Caucasian Population
  Molecular Vision. 2008  |   Pubmed ID: 18682806
• The NEI/NCBI DbGAP Database: Genotypes and Haplotypes That May Specifically Predispose to Risk of Neovascular Age-related Macular Degeneration
  BMC Medical Genetics. 2008  |   Pubmed ID: 18541031
• The Signatures of Autozygosity Among Patients with Colorectal Cancer
  Cancer Research. Apr, 2008  |   Pubmed ID: 18375840
• HTRA1 Variants in Exudative Age-related Macular Degeneration and Interactions with Smoking and CFH
  Investigative Ophthalmology & Visual Science. Jun, 2008  |   Pubmed ID: 18316707
• Functional and Structural Implications of the Complement Factor H Y402H Polymorphism Associated with Age-related Macular Degeneration
  Investigative Ophthalmology & Visual Science. May, 2008  |   Pubmed ID: 18263814
• Further Mapping of 10q26 Supports Strong Association of HTRA1 Polymorphisms with Age-related Macular Degeneration
  Vision Research. Feb, 2008  |   Pubmed ID: 18207215
• Linkage Disequilibrium Mapping for Complex Disease Genes
  Methods in Molecular Biology (Clifton, N.J.). 2007  |   Pubmed ID: 17984540
• Replicating Genotype-phenotype Associations
  Nature. Jun, 2007  |   Pubmed ID: 17554299
• Two Genetic Pathways for Age-related Macular Degeneration
  Current Opinion in Genetics & Development. Jun, 2007  |   Pubmed ID: 17467263
• Origin of Dendritic Cells in Peripheral Lymphoid Organs of Mice
  Nature Immunology. Jun, 2007  |   Pubmed ID: 17450143
• HTRA1 Promoter Polymorphism Predisposes Japanese to Age-related Macular Degeneration
  Molecular Vision. 2007  |   Pubmed ID: 17438519
• Fine-scale Linkage Disequilibrium Mapping of Age-related Macular Degeneration in the Complement Factor H Gene Region
  The British Journal of Ophthalmology. Jul, 2007  |   Pubmed ID: 17314151
• A Variant of the HTRA1 Gene Increases Susceptibility to Age-related Macular Degeneration
  Science (New York, N.Y.). Nov, 2006  |   Pubmed ID: 17053109
• HTRA1 Promoter Polymorphism in Wet Age-related Macular Degeneration
  Science (New York, N.Y.). Nov, 2006  |   Pubmed ID: 17053108
• Systematic Review and Meta-analysis of the Association Between Complement Factor H Y402H Polymorphisms and Age-related Macular Degeneration
  Human Molecular Genetics. Sep, 2006  |   Pubmed ID: 16905558
• Association of Angiotensinogen Gene Polymorphisms with Essential Hypertension in African-Americans and Caucasians
  Human Heredity. 2005  |   Pubmed ID: 16210856
• Strong Association of the Y402H Variant in Complement Factor H at 1q32 with Susceptibility to Age-related Macular Degeneration
  American Journal of Human Genetics. Jul, 2005  |   Pubmed ID: 15895326
• Complement Factor H Polymorphism in Age-related Macular Degeneration
  Science (New York, N.Y.). Apr, 2005  |   Pubmed ID: 15761122
• Genetic Dissection of Diseases: Design and Methods
  Current Opinion in Genetics & Development. Jun, 2004  |   Pubmed ID: 15172663
• Sum Statistics for the Joint Detection of Multiple Disease Loci in Case-control Association Studies with SNP Markers
  Genetic Epidemiology. Dec, 2003  |   Pubmed ID: 14639704
• Mathematical Multi-locus Approaches to Localizing Complex Human Trait Genes
  Nature Reviews. Genetics. Sep, 2003  |   Pubmed ID: 12951571
• Set Association Analysis of SNP Case-control and Microarray Data
  Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 2003  |   Pubmed ID: 12935345
• Statistical Methods for Analyzing Microarray Feature Data with Replications
  Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 2003  |   Pubmed ID: 12804089
• Efficiency of Single-nucleotide Polymorphism Haplotype Estimation from Pooled DNA
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2003  |   Pubmed ID: 12777616
• SNP Haplotype Tagging from DNA Pools of Two Individuals
  BMC Bioinformatics. Apr, 2003  |   Pubmed ID: 12709267
• Pharmacogenetic Analysis of Adverse Drug Effect Reveals Genetic Variant for Susceptibility to Liver Toxicity
  The Pharmacogenomics Journal. 2002  |   Pubmed ID: 12439739
• A Protein Kinase A-dependent Molecular Switch in Synapsins Regulates Neurite Outgrowth
  Nature Neuroscience. May, 2002  |   Pubmed ID: 11976703
• Asthma, Allergy, and Airway Hyperresponsiveness Are Not Linked to the Beta(2)-adrenoceptor Gene
  Chest. Mar, 2002  |   Pubmed ID: 11888952