Joshua D. Webster

Publications

• Reporting Guidelines for Manuscripts on Tumor Prognosis
  Veterinary Pathology. 05, 2022  |   Pubmed ID: 35220838
• Shigella Ubiquitin Ligase IpaH7.8 Targets Gasdermin D for Degradation to Prevent Pyroptosis and Enable Infection
  Cell Host & Microbe. 10, 2021  |   Pubmed ID: 34492225
• Genetic Inactivation of RIP1 Kinase Activity in Rats Protects Against Ischemic Brain Injury
  Cell Death & Disease. 04, 2021  |   Pubmed ID: 33828080
• NINJ1 Mediates Plasma Membrane Rupture During Lytic Cell Death
  Nature. 03, 2021  |   Pubmed ID: 33472215
• Impaired RIPK1 Ubiquitination Sensitizes Mice to TNF Toxicity and Inflammatory Cell Death
  Cell Death and Differentiation. 03, 2021  |   Pubmed ID: 32999468
• Genetic Inactivation of RIP1 Kinase Does Not Ameliorate Disease in a Mouse Model of ALS
  Cell Death and Differentiation. 03, 2021  |   Pubmed ID: 32994544
• Integration of Innate Immune Signalling by Caspase-8 Cleavage of N4BP1
  Nature. 11, 2020  |   Pubmed ID: 32971525
• Ubiquitin Ligase COP1 Suppresses Neuroinflammation by Degrading C/EBPβ in Microglia
  Cell. 09, 2020  |   Pubmed ID: 32795415
• The Balance of TNF Mediated Pathways Regulates Inflammatory Cell Death Signaling in Healthy and Diseased Tissues
  Frontiers in Cell and Developmental Biology. 2020  |   Pubmed ID: 32671059
• Single-Cell Transcriptome Profiling of the Kidney Glomerulus Identifies Key Cell Types and Reactions to Injury
  Journal of the American Society of Nephrology : JASN. 10, 2020  |   Pubmed ID: 32651223
• MAP4K4 Negatively Regulates CD8 T Cell-mediated Antitumor and Antiviral Immunity
  Science Immunology. 03, 2020  |   Pubmed ID: 32220977
• The Tumor Suppressor BAP1 Regulates the Hippo Pathway in Pancreatic Ductal Adenocarcinoma
  Cancer Research. 04, 2020  |   Pubmed ID: 31988076
• RIP1 Kinase Activity is Critical for Skin Inflammation but Not for Viral Propagation
  Journal of Leukocyte Biology. 06, 2020  |   Pubmed ID: 31985117
• Applications and Considerations for the Use of Genetically Engineered Mouse Models in Drug Development
  Cell and Tissue Research. May, 2020  |   Pubmed ID: 31486957
• Unobstructed Multiscale Imaging of Tissue Sections for Ultrastructural Pathology Analysis by Backscattered Electron Scanning Microscopy
  The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 01, 2020  |   Pubmed ID: 31385742
• RIP1 Inhibition Blocks Inflammatory Diseases but Not Tumor Growth or Metastases
  Cell Death and Differentiation. 01, 2020  |   Pubmed ID: 31101885
• Activity of Caspase-8 Determines Plasticity Between Cell Death Pathways
  Nature. 11, 2019  |   Pubmed ID: 31723262
• The RIPK4-IRF6 Signalling Axis Safeguards Epidermal Differentiation and Barrier Function
  Nature. 10, 2019  |   Pubmed ID: 31578523
• Cleavage of RIPK1 by Caspase-8 is Crucial for Limiting Apoptosis and Necroptosis
  Nature. 10, 2019  |   Pubmed ID: 31511692
• Prognostic and Predictive Significance of KIT Protein Expression and C-kit Gene Mutation in Canine Cutaneous Mast Cell Tumours: A Consensus of the Oncology-Pathology Working Group
  Veterinary and Comparative Oncology. Dec, 2019  |   Pubmed ID: 31264352
• Ubiquitin Ligases CIAP1 and CIAP2 Limit Cell Death to Prevent Inflammation
  Cell Reports. 05, 2019  |   Pubmed ID: 31141691
• Intrinsic Apoptosis Shapes the Tumor Spectrum Linked to Inactivation of the Deubiquitinase BAP1
  Science (New York, N.Y.). Apr, 2019  |   Pubmed ID: 31000662
• The Gag Protein PEG10 Binds to RNA and Regulates Trophoblast Stem Cell Lineage Specification
  PloS One. 2019  |   Pubmed ID: 30951545
• The Tumor Suppressor BAP1 Cooperates with BRAFV600E to Promote Tumor Formation in Cutaneous Melanoma
  Pigment Cell & Melanoma Research. 03, 2019  |   Pubmed ID: 30156010
• Ubiquitin Ligase COP1 Coordinates Transcriptional Programs That Control Cell Type Specification in the Developing Mouse Brain
  Proceedings of the National Academy of Sciences of the United States of America. 10, 2018  |   Pubmed ID: 30322923
• Observational Study Design in Veterinary Pathology, Part 2: Methodology
  Veterinary Pathology. Sep, 2018  |   Pubmed ID: 30227783
• The Hippo Pathway Effector TAZ Induces TEAD-dependent Liver Inflammation and Tumors
  Science Signaling. 09, 2018  |   Pubmed ID: 30206136
• Detection of Necroptosis by Phospho-RIPK3 Immunohistochemical Labeling
  Methods in Molecular Biology (Clifton, N.J.). 2018  |   Pubmed ID: 30136239
• Kinase Domain Dimerization Drives RIPK3-dependent Necroptosis
  Science Signaling. 08, 2018  |   Pubmed ID: 30131368
• Observational Study Design in Veterinary Pathology, Part 1: Study Design
  Veterinary Pathology. 09, 2018  |   Pubmed ID: 30071806
• OTULIN Limits Cell Death and Inflammation by Deubiquitinating LUBAC
  Nature. 07, 2018  |   Pubmed ID: 29950720
• Multifaceted Roles of Autophagy in Health and Disease
  Veterinary Pathology. 05, 2018  |   Pubmed ID: 29635994
• Coordinated Ubiquitination and Phosphorylation of RIP1 Regulates Necroptotic Cell Death
  Cell Death and Differentiation. 01, 2017  |   Pubmed ID: 27518435
• RIPK1 Inhibits ZBP1-driven Necroptosis During Development
  Nature. 12, 2016  |   Pubmed ID: 27819682
• Transcriptional Profiling of Canine Mast Cell Tumors: Searching for Candidate Targets and Prognostic Markers
  Veterinary Journal (London, England : 1997). 08, 2016  |   Pubmed ID: 27387731
• NeuCode Proteomics Reveals Bap1 Regulation of Metabolism
  Cell Reports. 07, 2016  |   Pubmed ID: 27373151
• Inhibition of the Kinase ITK in a Mouse Model of Asthma Reduces Cell Death and Fails to Inhibit the Inflammatory Response
  Science Signaling. Dec, 2015  |   Pubmed ID: 26628680
• β-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1
  Cell. Dec, 2015  |   Pubmed ID: 26627735
• Small Molecule Kinase Inhibitors in Veterinary Oncology
  Veterinary Journal (London, England : 1997). Aug, 2015  |   Pubmed ID: 25744806
• Immunohistochemical Detection of FLAG-tagged Endogenous Proteins in Knock-in Mice
  The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 04, 2015  |   Pubmed ID: 25575566
• Regulation of Proximal T Cell Receptor Signaling and Tolerance Induction by Deubiquitinase Usp9X
  The Journal of Experimental Medicine. Sep, 2014  |   Pubmed ID: 25200027
• Whole-slide Imaging and Automated Image Analysis: Considerations and Opportunities in the Practice of Pathology
  Veterinary Pathology. Jan, 2014  |   Pubmed ID: 24091812