Juan Carlos de la Torre Departments of Immunology and Microbial Sciences The Scripps Research Institute Biography Publications Institution JoVE Articles Juan Carlos de la Torre has not added a biography. If you are Juan Carlos de la Torre and would like to personalize this page please email our Author Liaison for assistance. Publications Inhibition of Multiplication of the Prototypic Arenavirus LCMV by Valproic Acid Antiviral Research. Aug, 2013 | Pubmed ID: 23735299 Persistent LCMV Infection is Controlled by Blockade of Type I Interferon Signaling Science (New York, N.Y.). Apr, 2013 | Pubmed ID: 23580529 Arenavirus Reverse Genetics for Vaccine Development The Journal of General Virology. Jun, 2013 | Pubmed ID: 23364194 JunÃn Virus Infection Activates the Type I Interferon Pathway in a RIG-I-dependent Manner PLoS Neglected Tropical Diseases. 2012 | Pubmed ID: 22629479 Arenavirus Nucleoprotein Targets Interferon Regulatory Factor-activating Kinase IKKε Journal of Virology. Aug, 2012 | Pubmed ID: 22532683 Mutagenesis-mediated Virus Extinction: Virus-dependent Effect of Viral Load on Sensitivity to Lethal Defection PloS One. 2012 | Pubmed ID: 22442668 The PI3K/Akt Pathway Contributes to Arenavirus Budding Journal of Virology. Apr, 2012 | Pubmed ID: 22345463 Evaluation of the Anti-arenaviral Activity of the Subtilisin Kexin Isozyme-1/site-1 Protease Inhibitor PF-429242 Virology. Feb, 2012 | Pubmed ID: 22154237 Arenavirus Budding Advances in Virology. 2011 | Pubmed ID: 22312335 Crystal Structure of the Lassa Virus Nucleoprotein-RNA Complex Reveals a Gating Mechanism for RNA Binding Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011 | Pubmed ID: 22084115 The C-terminal Region of Lymphocytic Choriomeningitis Virus Nucleoprotein Contains Distinct and Segregable Functional Domains Involved in NP-Z Interaction and Counteraction of the Type I Interferon Response Journal of Virology. Dec, 2011 | Pubmed ID: 21976642 The Ebola Virus Glycoprotein Mediates Entry Via a Non-classical Dynamin-dependent Macropinocytic Pathway Virology. Oct, 2011 | Pubmed ID: 21907381 Expanded Potential for Recombinant Trisegmented Lymphocytic Choriomeningitis Viruses: Protein Production, Antibody Production, and in Vivo Assessment of Biological Function of Genes of Interest Journal of Virology. Aug, 2011 | Pubmed ID: 21613399 Ribavirin Can Be Mutagenic for Arenaviruses Journal of Virology. Jul, 2011 | Pubmed ID: 21561907 Hypomorphic Mutation in the Site-1 Protease Mbtps1 Endows Resistance to Persistent Viral Infection in a Cell-specific Manner Cell Host & Microbe. Mar, 2011 | Pubmed ID: 21402360 Conserved Residues in Lassa Fever Virus Z Protein Modulate Viral Infectivity at the Level of the Ribonucleoprotein Journal of Virology. Apr, 2011 | Pubmed ID: 21228230 T-705 (favipiravir) Inhibition of Arenavirus Replication in Cell Culture Antimicrobial Agents and Chemotherapy. Feb, 2011 | Pubmed ID: 21115797 Role of the Host Cell's Unfolded Protein Response in Arenavirus Infection Journal of Virology. Feb, 2011 | Pubmed ID: 21106748 Antiviral Activity of a Small-molecule Inhibitor of Arenavirus Glycoprotein Processing by the Cellular Site 1 Protease Journal of Virology. Jan, 2011 | Pubmed ID: 21068251 Inhibition of the Type I Interferon Antiviral Response During Arenavirus Infection Viruses. Nov, 2010 | Pubmed ID: 21994626 Targeting the Proteolytic Processing of the Viral Glycoprotein Precursor is a Promising Novel Antiviral Strategy Against Arenaviruses Journal of Virology. Jan, 2010 | Pubmed ID: 19846507 The Z Protein of the New World Arenavirus Tacaribe Virus Has Bona Fide Budding Activity That Does Not Depend on Known Late Domain Motifs Journal of Virology. Dec, 2009 | Pubmed ID: 19759156 A Cell-based Luciferase Assay Amenable to High-throughput Screening of Inhibitors of Arenavirus Budding Virology. Dec, 2008 | Pubmed ID: 18929379 Different Mechanisms of Cell Entry by Human-pathogenic Old World and New World Arenaviruses Journal of Virology. Aug, 2008 | Pubmed ID: 18508885 Genomic and Biological Characterization of Aggressive and Docile Strains of Lymphocytic Choriomeningitis Virus Rescued from a Plasmid-based Reverse-genetics System The Journal of General Virology. Jun, 2008 | Pubmed ID: 18474558 Identification of MAVS Splicing Variants That Interfere with RIGI/MAVS Pathway Signaling Molecular Immunology. Apr, 2008 | Pubmed ID: 18207245 Borna Disease Virus RNA Detected in Japanese Macaques (Macaca Fuscata) Primates; Journal of Primatology. Jan, 2008 | Pubmed ID: 17929110 Differential Inhibition of Type I Interferon Induction by Arenavirus Nucleoproteins Journal of Virology. Nov, 2007 | Pubmed ID: 17804508 Mapping the Landscape of the Lymphocytic Choriomeningitis Virus Stable Signal Peptide Reveals Novel Functional Domains Journal of Virology. Jun, 2007 | Pubmed ID: 17376927 Inhibition of the Type I Interferon Response by the Nucleoprotein of the Prototypic Arenavirus Lymphocytic Choriomeningitis Virus Journal of Virology. Sep, 2006 | Pubmed ID: 16940530 Altered Central Nervous System Gene Expression Caused by Congenitally Acquired Persistent Infection with Lymphocytic Choriomeningitis Virus Journal of Virology. Sep, 2006 | Pubmed ID: 16940520 Envelope Exchange for the Generation of Live-attenuated Arenavirus Vaccines PLoS Pathogens. Jun, 2006 | Pubmed ID: 16751848 Recovery of an Arenavirus Entirely from RNA Polymerase I/II-driven CDNA Proceedings of the National Academy of Sciences of the United States of America. Mar, 2006 | Pubmed ID: 16537369 A Methionine-rich Domain Mediates CRM1-dependent Nuclear Export Activity of Borna Disease Virus Phosphoprotein Journal of Virology. Feb, 2006 | Pubmed ID: 16414989 Ube1L and Protein ISGylation Are Not Essential for Alpha/beta Interferon Signaling Molecular and Cellular Biology. Jan, 2006 | Pubmed ID: 16382139 Frontal Lobe Alterations in Schizophrenia: Neuroimaging and Neuropsychological Findings European Archives of Psychiatry and Clinical Neuroscience. Aug, 2005 | Pubmed ID: 16133741 RNA Interference-mediated Virus Clearance from Cells Both Acutely and Chronically Infected with the Prototypic Arenavirus Lymphocytic Choriomeningitis Virus Journal of Virology. Sep, 2005 | Pubmed ID: 16103158 Identification of the Borna Disease Virus (BDV) Proteins Required for the Formation of BDV-like Particles The Journal of General Virology. Jul, 2005 | Pubmed ID: 15958667 Functional Characterization of the Genomic Promoter of Borna Disease Virus (BDV): Implications of 3'-terminal Sequence Heterogeneity for BDV Persistence Journal of Virology. May, 2005 | Pubmed ID: 15858040 Dual Role of the Lymphocytic Choriomeningitis Virus Intergenic Region in Transcription Termination and Virus Propagation Journal of Virology. Apr, 2005 | Pubmed ID: 15767453 Arenavirus Extinction Through Lethal Mutagenesis Virus Research. Feb, 2005 | Pubmed ID: 15649566 Role of ISG15 Protease UBP43 (USP18) in Innate Immunity to Viral Infection Nature Medicine. Dec, 2004 | Pubmed ID: 15531891 Kinetics of Protective Antibodies Are Determined by the Viral Surface Antigen The Journal of Clinical Investigation. Oct, 2004 | Pubmed ID: 15467838 Myristoylation of the RING Finger Z Protein is Essential for Arenavirus Budding Journal of Virology. Oct, 2004 | Pubmed ID: 15452271 Bioterrorism and Emerging Infectious Disease - Antimicrobials, Therapeutics and Immune-modulators. Viral Infections IDrugs : the Investigational Drugs Journal. Feb, 2004 | Pubmed ID: 15057646 Cells Expressing the RING Finger Z Protein Are Resistant to Arenavirus Infection Journal of Virology. Mar, 2004 | Pubmed ID: 14990716 A Reverse Genetics System for Borna Disease Virus The Journal of General Virology. Nov, 2003 | Pubmed ID: 14573815 Mechanisms for Lymphocytic Choriomeningitis Virus Glycoprotein Cleavage, Transport, and Incorporation into Virions Virology. Sep, 2003 | Pubmed ID: 14517070 Recombinant Lymphocytic Choriomeningitis Virus Expressing Vesicular Stomatitis Virus Glycoprotein Proceedings of the National Academy of Sciences of the United States of America. Jun, 2003 | Pubmed ID: 12808132 Lethal Mutagenesis of the Prototypic Arenavirus Lymphocytic Choriomeningitis Virus (LCMV) Virology. Mar, 2003 | Pubmed ID: 12706088 Role of the Virus Nucleoprotein in the Regulation of Lymphocytic Choriomeningitis Virus Transcription and RNA Replication Journal of Virology. Mar, 2003 | Pubmed ID: 12610166 Characterization of the Genomic Promoter of the Prototypic Arenavirus Lymphocytic Choriomeningitis Virus Journal of Virology. Jan, 2003 | Pubmed ID: 12502835 Bornavirus and the Brain The Journal of Infectious Diseases. Dec, 2002 | Pubmed ID: 12424704 Characterization of the Arenavirus RING Finger Z Protein Regions Required for Z-mediated Inhibition of Viral RNA Synthesis Journal of Virology. Jul, 2002 | Pubmed ID: 12050381 Identification of the Lymphocytic Choriomeningitis Virus (LCMV) Proteins Required to Rescue LCMV RNA Analogs into LCMV-like Particles Journal of Virology. Jun, 2002 | Pubmed ID: 12021374 1-beta-D-arabinofuranosylcytosine Inhibits Borna Disease Virus Replication and Spread Journal of Virology. Jun, 2002 | Pubmed ID: 12021360 Molecular Biology of Borna Disease Virus and Persistence Frontiers in Bioscience : a Journal and Virtual Library. Feb, 2002 | Pubmed ID: 11815302 דור של Arenavirus רקומביננטי לפיתוח חיסון בתאי Vero-FDA Benson Y.H. Cheng*1, Emilio Ortiz-Riaño*1, Juan Carlos de la Torre2, Luis Martínez-Sobrido1 1Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, 2Departments of Immunology and Microbial Sciences, The Scripps Research Institute JoVE 50662 Immunology and Infection
דור של Arenavirus רקומביננטי לפיתוח חיסון בתאי Vero-FDA Benson Y.H. Cheng*1, Emilio Ortiz-Riaño*1, Juan Carlos de la Torre2, Luis Martínez-Sobrido1 1Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, 2Departments of Immunology and Microbial Sciences, The Scripps Research Institute JoVE 50662 Immunology and Infection