Julian H. Lombard Department of Physiology Medical College of Wisconsin Biography Publications Institution JoVE Articles Julian H. Lombard has not added a biography. If you are Julian H. Lombard and would like to personalize this page please email our Author Liaison for assistance. Publications NRF2 Activation with Protandim Attenuates Salt-induced Vascular Dysfunction and Microvascular Rarefaction Microcirculation (New York, N.Y. : 1994). 10, 2019 | Pubmed ID: 31132190 High Salt Diet Impairs Cerebral Blood Flow Regulation Via Salt-induced Angiotensin II Suppression Microcirculation (New York, N.Y. : 1994). 04, 2019 | Pubmed ID: 30481399 Do Computers Dream of Electric Glomeruli? Kidney International. 09, 2018 | Pubmed ID: 30143073 Region-Based Convolutional Neural Nets for Localization of Glomeruli in Trichrome-Stained Whole Kidney Sections Journal of the American Society of Nephrology : JASN. 08, 2018 | Pubmed ID: 29921718 High Salt Intake Shifts the Mechanisms of Flow-induced Dilation in the Middle Cerebral Arteries of Sprague-Dawley Rats American Journal of Physiology. Heart and Circulatory Physiology. 09, 2018 | Pubmed ID: 29906224 Contribution of Mitochondria-derived Free Radicals to Endothelial Dysfunction in Human Skeletal Muscle Feed Arteries: Another Hazard of the Ageing Process Acta Physiologica (Oxford, England). Aug, 2017 | Pubmed ID: 28834278 Mechanisms of Mas1 Receptor-Mediated Signaling in the Vascular Endothelium Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2017 | Pubmed ID: 28082260 Angiotensin-(1-7) Selectively Induces Relaxation and Modulates Endothelium-Dependent Dilation in Mesenteric Arteries of Salt-Fed Rats Journal of Vascular Research. Month, 2016 | Pubmed ID: 27676088 Role of Vascular Reactive Oxygen Species in Regulating Cytochrome P450-4A Enzyme Expression in Dahl Salt-sensitive Rats Microcirculation (New York, N.Y. : 1994). Oct, 2016 | Pubmed ID: 27537772 Increased Peripheral Vascular Disease Risk Progressively Constrains Perfusion Adaptability in the Skeletal Muscle Microcirculation American Journal of Physiology. Heart and Circulatory Physiology. Feb, 2016 | Pubmed ID: 26702145 The NRF2 Knockout Rat: a New Animal Model to Study Endothelial Dysfunction, Oxidant Stress, and Microvascular Rarefaction American Journal of Physiology. Heart and Circulatory Physiology. Feb, 2016 | Pubmed ID: 26637559 Salt, Angiotensin II, Superoxide, and Endothelial Function Comprehensive Physiology. Dec, 2015 | Pubmed ID: 26756632 The Role of Cyclo-oxygenase-1 in High-salt Diet-induced Microvascular Dysfunction in Humans The Journal of Physiology. Dec, 2015 | Pubmed ID: 26498129 Enhancement of Resting-state FcMRI Networks by Prior Sensory Stimulation Brain Connectivity. Nov, 2014 | Pubmed ID: 25387238 Vascular Dysfunction Precedes Hypertension Associated with a Blood Pressure Locus on Rat Chromosome 12 American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2014 | Pubmed ID: 25320330 Mutation of Plekha7 Attenuates Salt-sensitive Hypertension in the Rat Proceedings of the National Academy of Sciences of the United States of America. Sep, 2014 | Pubmed ID: 25136115 Response to "Does Angiotensin-dependent Superoxide Production Help to Prevent Salt-induced Endothelial Dysfunction in 2 Kidney-1 Clip Hypertensive Rats?" American Journal of Hypertension. Apr, 2014 | Pubmed ID: 24614863 Amelioration of Salt-induced Vascular Dysfunction in Mesenteric Arteries of Dahl Salt-sensitive Rats by Missense Mutation of Extracellular Superoxide Dismutase American Journal of Physiology. Heart and Circulatory Physiology. Feb, 2014 | Pubmed ID: 24322611 FMRI and FcMRI Phenotypes Map the Genomic Effect of Chromosome 13 in Brown Norway and Dahl Salt-sensitive Rats NeuroImage. Apr, 2014 | Pubmed ID: 24084065 AT1 Receptors Prevent Salt-induced Vascular Dysfunction in Isolated Middle Cerebral Arteries of 2 Kidney-1 Clip Hypertensive Rats American Journal of Hypertension. Dec, 2013 | Pubmed ID: 23934707 Reduced Angiotensin II Levels Cause Generalized Vascular Dysfunction Via Oxidant Stress in Hamster Cheek Pouch Arterioles Microvascular Research. Sep, 2013 | Pubmed ID: 23628292 Deficiency of Renal Cortical EGF Increases ENaC Activity and Contributes to Salt-sensitive Hypertension Journal of the American Society of Nephrology : JASN. Jun, 2013 | Pubmed ID: 23599382 Low-dose Angiotensin II Infusion Restores Vascular Function in Cerebral Arteries of High Salt-fed Rats by Increasing Copper/zinc Superoxide Dimutase Expression American Journal of Hypertension. Jun, 2013 | Pubmed ID: 23443725 Role of the CYP4A/20-HETE Pathway in Vascular Dysfunction of the Dahl Salt-sensitive Rat Clinical Science (London, England : 1979). Jun, 2013 | Pubmed ID: 23438293 Introgression of Brown Norway CYP4A Genes on to the Dahl Salt-sensitive Background Restores Vascular Function in SS-5(BN) Consomic Rats Clinical Science (London, England : 1979). Mar, 2013 | Pubmed ID: 22938512 PPAR-ϒ Pathway to Vascular Dysfunction Cell Metabolism. Oct, 2012 | Pubmed ID: 23040065 Dahl Salt-sensitive Rats Are Protected Against Vascular Defects Related to Diet-induced Obesity Hypertension (Dallas, Tex. : 1979). Aug, 2012 | Pubmed ID: 22710645 Acute and Chronic Angiotensin-(1-7) Restores Vasodilation and Reduces Oxidative Stress in Mesenteric Arteries of Salt-fed Rats American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2011 | Pubmed ID: 21803946 Introgression of the Brown Norway Renin Allele Onto the Dahl Salt-sensitive Genetic Background Increases Cu/Zn SOD Expression in Cerebral Arteries American Journal of Hypertension. May, 2011 | Pubmed ID: 21331057 Modulation by Cytochrome P450-4A ω-hydroxylase Enzymes of Adrenergic Vasoconstriction and Response to Reduced PO₂ in Mesenteric Resistance Arteries of Dahl Salt-sensitive Rats Microcirculation (New York, N.Y. : 1994). Oct, 2010 | Pubmed ID: 21040118 Impaired Relaxation of Cerebral Arteries in the Absence of Elevated Salt Intake in Normotensive Congenic Rats Carrying the Dahl Salt-sensitive Renin Gene American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2010 | Pubmed ID: 20852041 Vascular Responses in Aortic Rings of a Consomic Rat Panel Derived from the Fawn Hooded Hypertensive Strain Physiological Genomics. Nov, 2010 | Pubmed ID: 20841496 Angiotensin-(1-7) and Low-dose Angiotensin II Infusion Reverse Salt-induced Endothelial Dysfunction Via Different Mechanisms in Rat Middle Cerebral Arteries American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2010 | Pubmed ID: 20656887 Uncoupling Protein 2 (UCP2): Another Player in the Complex Drama of Vascular Salt Sensitivity American Journal of Hypertension. Aug, 2010 | Pubmed ID: 20644528 Restoration of Cerebral Vascular Relaxation in Renin Congenic Rats by Introgression of the Dahl R Renin Gene American Journal of Hypertension. Mar, 2010 | Pubmed ID: 19959997 CYP450 4A Inhibition Attenuates O2 Induced Arteriolar Constriction in Chronic but Not Acute Goldblatt Hypertension Microvascular Research. Dec, 2009 | Pubmed ID: 19761780 Angiotensin II Maintains Cerebral Vascular Relaxation Via EGF Receptor Transactivation and ERK1/2 American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2009 | Pubmed ID: 19684181 Reduced Oxidant Stress, Increased NO-dependent Vasodilatation, and Improved Endothelial Function with Voluntary Exercise in Old Mice: Another Excuse for Long Walks on the Beach The Journal of Physiology. Jul, 2009 | Pubmed ID: 19567741 Time-course and Mechanisms of Restored Vascular Relaxation by Reduced Salt Intake and Angiotensin II Infusion in Rats Fed a High-salt Diet Microcirculation (New York, N.Y. : 1994). Apr, 2009 | Pubmed ID: 19235625 Modulation of Vascular O2 Responses by Cytochrome 450-4A Omega-hydroxylase Metabolites in Dahl Salt-sensitive Rats Microcirculation (New York, N.Y. : 1994). May, 2009 | Pubmed ID: 19225982 Effect of High-salt Diet on Vascular Relaxation and Oxidative Stress in Mesenteric Resistance Arteries Journal of Vascular Research. Month, 2007 | Pubmed ID: 17510561 Role of Superoxide and Angiotensin II Suppression in Salt-induced Changes in Endothelial Ca2+ Signaling and NO Production in Rat Aorta American Journal of Physiology. Heart and Circulatory Physiology. Aug, 2006 | Pubmed ID: 16603691 BN Phenome: Detailed Characterization of the Cardiovascular, Renal, and Pulmonary Systems of the Sequenced Rat Physiological Genomics. Apr, 2006 | Pubmed ID: 16478827 Chronic Intermittent Hypoxia Alters NE Reactivity and Mechanics of Skeletal Muscle Resistance Arteries Journal of Applied Physiology (Bethesda, Md. : 1985). Apr, 2006 | Pubmed ID: 16357071 Chronic At1 Receptor Blockade Alters the Mechanisms Mediating Hypoxic Dilation in Middle Cerebral Arteries Journal of Cardiovascular Pharmacology. Nov, 2005 | Pubmed ID: 16220079 Restoration of Normal Vascular Relaxation Mechanisms in Cerebral Arteries by Chromosomal Substitution in Consomic SS.13BN Rats American Journal of Physiology. Heart and Circulatory Physiology. Jul, 2005 | Pubmed ID: 15778273 Reduced Angiotensin II and Oxidative Stress Contribute to Impaired Vasodilation in Dahl Salt-sensitive Rats on Low-salt Diet Hypertension (Dallas, Tex. : 1979). Apr, 2005 | Pubmed ID: 15710779 Effects of High-salt Diet on CYP450-4A Omega-hydroxylase Expression and Active Tone in Mesenteric Resistance Arteries American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2005 | Pubmed ID: 15576442 Salt-induced ANG II Suppression Impairs the Response of Cerebral Artery Smooth Muscle Cells to Prostacyclin American Journal of Physiology. Heart and Circulatory Physiology. Feb, 2005 | Pubmed ID: 15486030 Arteriolar Responses to Vasodilator Stimuli and Elevated P(O2) in Renin Congenic and Dahl Salt-sensitive Rats Microcirculation (New York, N.Y. : 1994). Dec, 2004 | Pubmed ID: 15726834 Expression of Cytochrome P450-4A Isoforms in the Rat Cremaster Muscle Microcirculation Microcirculation (New York, N.Y. : 1994). Jan-Feb, 2004 | Pubmed ID: 15280100 Evaluation of Cytochrome P450-4A Omega-hydroxylase and 20-hydroxyeicosatetraenoic Acid As an O2 Sensing Mechanism in the Microcirculation Methods in Enzymology. Month, 2004 | Pubmed ID: 15063671 Chronic AT(1) Receptor Blockade Alters Mechanisms Mediating Responses to Hypoxia in Rat Skeletal Muscle Resistance Arteries American Journal of Physiology. Heart and Circulatory Physiology. Aug, 2004 | Pubmed ID: 15044197 Introgression of Chromosome 13 in Dahl Salt-sensitive Genetic Background Restores Cerebral Vascular Relaxation American Journal of Physiology. Heart and Circulatory Physiology. Aug, 2004 | Pubmed ID: 15031125 Effect of High-salt Diet on NO Release and Superoxide Production in Rat Aorta American Journal of Physiology. Heart and Circulatory Physiology. Feb, 2004 | Pubmed ID: 14527935 Chronic Intermittent Hypoxia Impairs Endothelium-dependent Dilation in Rat Cerebral and Skeletal Muscle Resistance Arteries American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2004 | Pubmed ID: 14512283 Skeletal Muscle Arteriolar Reactivity in SS.BN13 Consomic Rats and Dahl Salt-sensitive Rats Hypertension. May, 2003 | Pubmed ID: 12682080 High-salt Diet Impairs Vascular Relaxation Mechanisms in Rat Middle Cerebral Arteries American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2003 | Pubmed ID: 12456391 Interaction of Myogenic Mechanisms and Hypoxic Dilation in Rat Middle Cerebral Arteries American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2002 | Pubmed ID: 12388266 Foreword to the Special Issue on Microcirculatory Adaptations to Hypertension Microcirculation (New York, N.Y. : 1994). Month, 2002 | Pubmed ID: 12152100 Integration of Hypoxic Dilation Signaling Pathways for Skeletal Muscle Resistance Arteries American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Aug, 2002 | Pubmed ID: 12121842 High-salt Diet Depresses Acetylcholine Reactivity Proximal to NOS Activation in Cerebral Arteries American Journal of Physiology. Heart and Circulatory Physiology. Jul, 2002 | Pubmed ID: 12063309 Parenchymal Tissue Cytochrome P450 4A Enzymes Contribute to Oxygen-induced Alterations in Skeletal Muscle Arteriolar Tone Microvascular Research. May, 2002 | Pubmed ID: 11969311 Microvascular Flow and Tissue PO(2) in Skeletal Muscle of Chronic Reduced Renal Mass Hypertensive Rats American Journal of Physiology. Heart and Circulatory Physiology. Nov, 2000 | Pubmed ID: 11045965 使用激光多普勒流测量测量大鼠脑血流自动调节的评估 Linda A. Allen*1, Maia Terashvili*1, Alison Gifford*1, Julian H. Lombard1 1Department of Physiology, Medical College of Wisconsin JoVE 60540 Medicine 利用大鼠离体阻力动脉的视频显微镜对血管控制机制的评价 Kathleen M. Lukaszewicz1, Matthew J. Durand2, Jessica R.C. Priestley3, James R. Schmidt4, L. Adrienne Allen5, Aron M. Geurts3, Julian H. Lombard3 1Department of Physical Therapy, Marquette University, 2Medical College of Wisconsin, 3Department of Physiology, Medical College of Wisconsin, 4Graduate Programs of Nurse Anesthesia, Texas Wesleyan University, 5Office of Research, Medical College of Wisconsin JoVE 56133 Medicine
使用激光多普勒流测量测量大鼠脑血流自动调节的评估 Linda A. Allen*1, Maia Terashvili*1, Alison Gifford*1, Julian H. Lombard1 1Department of Physiology, Medical College of Wisconsin JoVE 60540 Medicine
利用大鼠离体阻力动脉的视频显微镜对血管控制机制的评价 Kathleen M. Lukaszewicz1, Matthew J. Durand2, Jessica R.C. Priestley3, James R. Schmidt4, L. Adrienne Allen5, Aron M. Geurts3, Julian H. Lombard3 1Department of Physical Therapy, Marquette University, 2Medical College of Wisconsin, 3Department of Physiology, Medical College of Wisconsin, 4Graduate Programs of Nurse Anesthesia, Texas Wesleyan University, 5Office of Research, Medical College of Wisconsin JoVE 56133 Medicine
