Jun Yang

Department of Physiology, School of Medicine

Zhejiang University

Jun Yang
Professor

Dr. Jun YANG is a principal investigator at Department of Physiology, Zhejiang University School of Medicine. She was recruited from University of Cambridge in 2014 by “The National Recruitment Program of Global Experts”to be Professor of Department of Cell Biology, Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences. Then she moved to Zhejiang University and funded by the 'Hundred Talents Program' in 2019.

She had undergraduate education in Zhejiang University, and received her Ph.D. degree from Chinese Academy of Medical Sciences & Peking Union Medical College. She devoted on the medical research of cardiopulmonary disease for more than 8 years in university of Cambridge with Professor Nick Morrell. Combined with her expertise on the drug discovery she applied stem cell technology to drug screening for small molecular intervention on BMPR2 signaling for the treatment of pulmonary arterial hypertension. The Yang lab sets up the human inducible pluoripotent stem cell reprogramming and differentiation syestem to study the pathogenesis of related diseases. Also her group professionally generates mutaions in human embroynic stem cells for understanding the vascular development as well as performs mutation correction for potential cell therapy.

She has published more than 30 research papers in the national and internationally recognized journals, including European Respiratory Journal, Circulation Research and Am J Respir Crit Care Med, and applied more than 5 national and international patents. She was awarded British Associate of Lung Research young investigator first prize in British Thoracic Society meeting and Pfizer European pulmonary vascular disease research. Her current project is aim to study the cellular and molecular pathogenesis of cardiopulmonary disease.

Publications

Whole-Mount In Situ Hybridization in Zebrafish Embryos and Tube Formation Assay in iPSC-ECs to Study the Role of Endoglin in Vascular Development

1Department of Physiology and Department of Cardiology of the Second Affiliated Hospital, Zhejiang University School of Medicine, 2Department of Cell Biology, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, 3Wuxi Lung Transplant Center, Wuxi People's Hospital affiliated to Nanjing Medical University

JoVE 60498

 Developmental Biology