Junhui Hu

Department of Molecular and Medical Pharmacology

David Geffen School of Medicine, University of California, Los Angeles

Junhui Hu

Junhui Hu is an Assistant Project Scientist in the Department of Molecular and Medical Pharmacology, University of California, Los Angeles (UCLA) in Los Angeles, California. he received his Bachelor’s Degree in Computer Science and M.D./Ph.D degree in Huazhong University of Science and Technology (HUST) in Wuhan, China.

During Dr. Hu’s training as a research physician (2012-2015), he developed the interest in broad fields of cancer research but mainly falls in the big category of how tumor heterogeneity contributes cancer progression and metastasis. In the study of urological cancers especially clear cell renal cell carcinoma (ccRCC), he investigated cancer stem cells and noncoding RNAs, and established CD105 as both a cancer stem cell marker and a functional target. In addition, he learned and developed the orthotopic kidney cancer mouse model as a standard animal model for his continued study in tumor heterogeneity of VHL in ccRCC.

Then he moved to Lily Wu’s lab in University of California, Los Angeles (UCLA), USA, as a postdoctoral trainee (2015) and was later recruited as an Assistant Project Scientist. His research program includes the tumor associated macrophages mitigating the chemoresistance in castration resistant prostate cancer, epithelial-mesenchymal transition (EMT) and VHL heterogeneity in cancer progression, and the development of metastatic ccRCC animal models in mice and chicken embryos.

Publications

Confrontando il modello di carcinoma a cellule renali a celle chiare metastatico stabilito nel rene del topo e sulla membrana coroallantoica del pollo

*1, *1, 2, 3, 4, 5, 6, 7, 1, 1,8

1Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, 2Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, 3Department of Bioengineering, Hanyang University, 4Department of Ecology and Evolutionary Biology, University of California, Los Angeles, 5Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, 6School of Life Sciences, Beijing Normal University, 7Department of Urology, West China Hospital, Sichuan University, 8Department of Urology, David Geffen School of Medicine, University of California, Los Angeles

JoVE 60314

 Cancer Research