K. George Chandy Lee Kong Chian School of Medicine Nanyang Technological University Biography Publications Institution JoVE Articles K. George Chandy has not added a biography. If you are K. George Chandy and would like to personalize this page please email our Author Liaison for assistance. Publications Peptide Blockers of Kv1.3 Channels in T Cells As Therapeutics for Autoimmune Disease Current Opinion in Chemical Biology. Apr, 2017 | Pubmed ID: 28412597 Tissue Resident Memory T Cells in the Human Conjunctiva and Immune Signatures in Human Dry Eye Disease Scientific Reports. Mar, 2017 | Pubmed ID: 28345628 International Union of Basic and Clinical Pharmacology. C. Nomenclature and Properties of Calcium-Activated and Sodium-Activated Potassium Channels Pharmacological Reviews. Jan, 2017 | Pubmed ID: 28267675 Immunology: Channelling Potassium to Fight Cancer Nature. 09, 2016 | Pubmed ID: 27626384 Kv1.3 Channel-blocking Immunomodulatory Peptides from Parasitic Worms: Implications for Autoimmune Diseases FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2014 | Pubmed ID: 24891519 Blockade of Kv1.3 Channels Ameliorates Radiation-induced Brain Injury Neuro-oncology. Apr, 2014 | Pubmed ID: 24305723 Shaker-related Potassium Channels in the Central Medial Nucleus of the Thalamus Are Important Molecular Targets for Arousal Suppression by Volatile General Anesthetics The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2013 | Pubmed ID: 24107962 Selective Kv1.3 Channel Blocker As Therapeutic for Obesity and Insulin Resistance Proceedings of the National Academy of Sciences of the United States of America. Jun, 2013 | Pubmed ID: 23729813 Intracellular Trafficking of the KV1.3 Potassium Channel is Regulated by the Prodomain of a Matrix Metalloprotease The Journal of Biological Chemistry. Mar, 2013 | Pubmed ID: 23300077 Modulation of Voltage-gated K+ Channels by the Sodium Channel β1 Subunit Proceedings of the National Academy of Sciences of the United States of America. Nov, 2012 | Pubmed ID: 23090990 从多肽药物宋慧乔-186,具体的 Kv1.3 通道抑制剂能抑制 T 细胞的自身免疫性疾病的调解员的持久药理反应。 The Journal of Pharmacology and Experimental Therapeutics. May, 2012 | Pubmed ID: 22637724 Kv1.3 Deletion Biases T Cells Toward an Immunoregulatory Phenotype and Renders Mice Resistant to Autoimmune Encephalomyelitis Journal of Immunology (Baltimore, Md. : 1950). Jun, 2012 | Pubmed ID: 22581856 Inhibitors of Mitochondrial Kv1.3 Channels Induce Bax/Bak-independent Death of Cancer Cells EMBO Molecular Medicine. Jul, 2012 | Pubmed ID: 22496117 海葵毒素作为免疫调节剂治疗自身免疫性疾病的发展。 Toxicon : Official Journal of the International Society on Toxinology. Aug, 2011 | Pubmed ID: 21867724 目标离子通道的多肽毒素的治疗潜力。 Inflammation & Allergy Drug Targets. Oct, 2011 | Pubmed ID: 21745182 18F Fallypride 宠物的胰岛: 体外和体内的啮齿动物研究。 Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jul, 2011 | Pubmed ID: 21680697 遗传和环境趋同于 Dysregulate N-糖基化在多发性硬化症。 Nature Communications. 2011 | Pubmed ID: 21629267 钾通道调制的毒素域中基质金属蛋白酶 23。 The Journal of Biological Chemistry. Mar, 2010 | Pubmed ID: 19965868 T 淋巴细胞中的离子通道的功能网络。 Immunological Reviews. Sep, 2009 | Pubmed ID: 19754890 Kv1.3 钾通道作为多发性硬化症的治疗靶点。 Expert Opinion on Therapeutic Targets. Aug, 2009 | Pubmed ID: 19538097 成像的效应记忆 T 细胞超敏反应和抑制期间由 Kv1.3 通道块。 Immunity. Oct, 2008 | Pubmed ID: 18835197 中间电导钙激活钾通道 KCa3.1 有助于人类和小鼠动脉粥样硬化。 The Journal of Clinical Investigation. Sep, 2008 | Pubmed ID: 18688283 D-diastereomer 的宋慧乔毒素有选择性地阻止电压门控 K + 通道和抑制 T 淋巴细胞增殖。 The Journal of Biological Chemistry. Jan, 2008 | Pubmed ID: 17984097 Kv1.3 通道是 T 细胞介导的自身免疫性疾病的治疗目标。 Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006 | Pubmed ID: 17088564 国际药学联合会。LIII.术语和电压门控性钾通道的分子关系。 Pharmacological Reviews. Dec, 2005 | Pubmed ID: 16382104 国际药学联合会。LII.术语和钙激活钾通道的分子关系。 Pharmacological Reviews. Dec, 2005 | Pubmed ID: 16382103 钾通道、 记忆 T 细胞和多发性硬化症。 The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. Dec, 2005 | Pubmed ID: 16282596 电压门控性钾通道 Kv1.3 高度对多发性硬化脑内炎症浸润。 Proceedings of the National Academy of Sciences of the United States of America. Aug, 2005 | Pubmed ID: 16043714 靶向效应记忆 T 细胞与一种选择性多肽抑制剂 Kv1.3 通道的自身免疫性疾病的治疗。 Molecular Pharmacology. Apr, 2005 | Pubmed ID: 15665253 K + B 细胞分化过程的渠道表达: 对免疫调节与自身免疫的影响。 Journal of Immunology (Baltimore, Md. : 1950). Jul, 2004 | Pubmed ID: 15240664 Kv1.3 阻塞 5-phenylalkoxypsoralens: 一类新的免疫调节剂。 Molecular Pharmacology. Jun, 2004 | Pubmed ID: 15155830 K + 通道作为特定免疫调节的目标。 Trends in Pharmacological Sciences. May, 2004 | Pubmed ID: 15120495 SKCa 渠道调解中等但不是慢钙激活 Afterhyperpolarization 皮层神经元。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2004 | Pubmed ID: 15071101 增强神经元兴奋性神经变性缺席诱导小脑共济失调。 The Journal of Clinical Investigation. Feb, 2004 | Pubmed ID: 14966567 SK3-1 C、 显性负抑癌 SKCa 和 IKCa 的渠道。 The Journal of Biological Chemistry. Feb, 2004 | Pubmed ID: 14638680 国际药学联合会。XLI.简编电压门控离子通道: 钾通道。 Pharmacological Reviews. Dec, 2003 | Pubmed ID: 14657415 钾通道为自身免疫性疾病的治疗目标。 Current Opinion in Drug Discovery & Development. Sep, 2003 | Pubmed ID: 14579513 作为一种新的治疗战略再狭窄的中间电导钙激活钾通道的封锁。 Circulation. Sep, 2003 | Pubmed ID: 12939222 电压门控 Kv1.3 K(+) 通道效应记忆 T 细胞为 MS 的新目标。 The Journal of Clinical Investigation. Jun, 2003 | Pubmed ID: 12782673 新型荧光的毒素,侦查和调查 Kv1.3 通道上调长期激活的 T 淋巴细胞。 The Journal of Biological Chemistry. Mar, 2003 | Pubmed ID: 12511563 变异关键的赖氨酸在宋慧乔毒素会改变其孔隙前庭地区的电压门控性钾通道,Kv1.3 的绑定配置。 Biochemistry. Oct, 2002 | Pubmed ID: 12356296 人类的电压门控性钾通道基因、 KCNA7、 候选基因遗传的心脏疾病和其排斥,因为会导致逐步家族性心脏传导阻滞的我 (PFHBI) 的特征。 European Journal of Human Genetics : EJHG. Jan, 2002 | Pubmed ID: 11896454 潘氏细胞 α-防御素分泌的 MIKCa1,Ca2 + 鼠标调制-激活的中间电导钾通道。 The Journal of Biological Chemistry. Feb, 2002 | Pubmed ID: 11724775 从结膜分离和表型细胞的非侵入性方式 Tanima Bose1, Aihua Hou2, Ryan Lee2, Louis Tong2,3,4,5, K. George Chandy1 1Lee Kong Chian School of Medicine, Nanyang Technological University, 2Singapore Eye Research Institute, 3Singapore National Eye Center, 4Duke-NUS Medical School, 5Yong Loo Lin School of Medicine JoVE 55591 Immunology and Infection 慢性自身免疫性干眼鼠模型增加效应记忆T细胞在眼球组织 Aihua Hou1,2, Tanima Bose3, K. George Chandy3, Louis Tong1,2,4,5 1Singapore Eye Research Insitute, A Member of SingHealth, 2DUKE-National University of Singapore Medical School, 3Lee Kong Chian School of Medicine, Nanyang Technological University, 4Singapore National Eye Center, 5Yong Loo Lin School of Medicine, National University of Singapore JoVE 55592 Immunology and Infection 成像效应在耳朵上的记忆体T细胞诱导后收养的DTH Melanie P. Matheu1, Christine Beeton1, Ian Parker2, K. George Chandy1, Michael D. Cahalan1 1Department of Physiology and Biophysics, University of California, Irvine (UCI), 2Department of Neurobiology and Behavior, University of California, Irvine (UCI) JoVE 907 Biology 从中央与EAE大鼠中枢神经系统的单核细胞的分离 Christine Beeton1, K. George Chandy1 1Department of Physiology and Biophysics, University of California, Irvine (UCI) JoVE 527 Biology 准备从大鼠脾细胞T细胞生长因子 Christine Beeton1, K. George Chandy1 1Department of Physiology and Biophysics, University of California, Irvine (UCI) JoVE 402 Biology NK细胞与干细胞技术的RosetteSep套件的人体血液的富集 Christine Beeton1, K. George Chandy1 1Department of Physiology and Biophysics, University of California, Irvine (UCI) JoVE 326 Biology 免疫组化:石蜡切片从Vector实验室使用Vectastain ABC试剂盒 Victor Chi1, K. George Chandy1 1Department of Physiology and Biophysics, University of California, Irvine (UCI) JoVE 308 Biology 收养大鼠迟发型超敏反应的感应和监测 Christine Beeton1, K. George Chandy1 1Department of Physiology and Biophysics, University of California, Irvine (UCI) JoVE 325 Biology 从老鼠血液通过大隐静脉和心脏穿刺“ Christine Beeton1, Adriana Garcia1, K. George Chandy1 1Department of Physiology and Biophysics, University of California, Irvine (UCI) JoVE 266 Biology 大鼠主动迟发型超敏反应(DTH)的诱导和监控 Christine Beeton1, K. George Chandy1 1Department of Physiology and Biophysics, University of California, Irvine (UCI) JoVE 237 Biology 归纳和慢性复发性实验性自身免疫性脑脊髓炎的临床评分 Christine Beeton1, Adriana Garcia1, K. George Chandy1 1Department of Physiology and Biophysics, University of California, Irvine (UCI) JoVE 224 Biology 鼠标肾上腺嗜铬细胞分离 Aaron Kolski-Andreaco1, Haijiang Cai2,3, D. Spencer Currle4, K. George Chandy1, Robert H. Chow2,3 1Department of Physiology and Biophysics, University of California, Irvine (UCI), 2Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, 3Zilkha Neurogenetic Institute, University of Southern California, Keck School of Medicine, 4Department of Developmental and Cell Biology, University of California, Irvine (UCI) JoVE 129 Biology
从结膜分离和表型细胞的非侵入性方式 Tanima Bose1, Aihua Hou2, Ryan Lee2, Louis Tong2,3,4,5, K. George Chandy1 1Lee Kong Chian School of Medicine, Nanyang Technological University, 2Singapore Eye Research Institute, 3Singapore National Eye Center, 4Duke-NUS Medical School, 5Yong Loo Lin School of Medicine JoVE 55591 Immunology and Infection
慢性自身免疫性干眼鼠模型增加效应记忆T细胞在眼球组织 Aihua Hou1,2, Tanima Bose3, K. George Chandy3, Louis Tong1,2,4,5 1Singapore Eye Research Insitute, A Member of SingHealth, 2DUKE-National University of Singapore Medical School, 3Lee Kong Chian School of Medicine, Nanyang Technological University, 4Singapore National Eye Center, 5Yong Loo Lin School of Medicine, National University of Singapore JoVE 55592 Immunology and Infection
成像效应在耳朵上的记忆体T细胞诱导后收养的DTH Melanie P. Matheu1, Christine Beeton1, Ian Parker2, K. George Chandy1, Michael D. Cahalan1 1Department of Physiology and Biophysics, University of California, Irvine (UCI), 2Department of Neurobiology and Behavior, University of California, Irvine (UCI) JoVE 907 Biology
从中央与EAE大鼠中枢神经系统的单核细胞的分离 Christine Beeton1, K. George Chandy1 1Department of Physiology and Biophysics, University of California, Irvine (UCI) JoVE 527 Biology
准备从大鼠脾细胞T细胞生长因子 Christine Beeton1, K. George Chandy1 1Department of Physiology and Biophysics, University of California, Irvine (UCI) JoVE 402 Biology
NK细胞与干细胞技术的RosetteSep套件的人体血液的富集 Christine Beeton1, K. George Chandy1 1Department of Physiology and Biophysics, University of California, Irvine (UCI) JoVE 326 Biology
免疫组化:石蜡切片从Vector实验室使用Vectastain ABC试剂盒 Victor Chi1, K. George Chandy1 1Department of Physiology and Biophysics, University of California, Irvine (UCI) JoVE 308 Biology
收养大鼠迟发型超敏反应的感应和监测 Christine Beeton1, K. George Chandy1 1Department of Physiology and Biophysics, University of California, Irvine (UCI) JoVE 325 Biology
从老鼠血液通过大隐静脉和心脏穿刺“ Christine Beeton1, Adriana Garcia1, K. George Chandy1 1Department of Physiology and Biophysics, University of California, Irvine (UCI) JoVE 266 Biology
大鼠主动迟发型超敏反应(DTH)的诱导和监控 Christine Beeton1, K. George Chandy1 1Department of Physiology and Biophysics, University of California, Irvine (UCI) JoVE 237 Biology
归纳和慢性复发性实验性自身免疫性脑脊髓炎的临床评分 Christine Beeton1, Adriana Garcia1, K. George Chandy1 1Department of Physiology and Biophysics, University of California, Irvine (UCI) JoVE 224 Biology
鼠标肾上腺嗜铬细胞分离 Aaron Kolski-Andreaco1, Haijiang Cai2,3, D. Spencer Currle4, K. George Chandy1, Robert H. Chow2,3 1Department of Physiology and Biophysics, University of California, Irvine (UCI), 2Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, 3Zilkha Neurogenetic Institute, University of Southern California, Keck School of Medicine, 4Department of Developmental and Cell Biology, University of California, Irvine (UCI) JoVE 129 Biology