Karen M. Dobos Mycobacteria Research Laboratories, Department of Microbiology Immunology & Pathology Colorado State University Biography Publications Institution JoVE Articles Karen M. Dobos has not added a biography. If you are Karen M. Dobos and would like to personalize this page please email our Author Liaison for assistance. Publications Sub-Lineage Specific Phenolic Glycolipid Patterns in the Complex Lineage 1 Frontiers in Microbiology. 2022 | Pubmed ID: 35350619 Structural Implications of Lipoarabinomannan Glycans from Global Clinical Isolates in Diagnosis of Mycobacterium Tuberculosis Infection The Journal of Biological Chemistry. 11, 2021 | Pubmed ID: 34600887 Methods for Proteomic Analyses of Mycobacteria Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 34235669 Extraction and Separation of Mycobacterial Proteins Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 34235649 Culturing Mycobacteria Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 34235647 Reuse of Disposable Isolation Gowns in Rodent Facilities During a Pandemic Journal of the American Association for Laboratory Animal Science : JAALAS. 07, 2021 | Pubmed ID: 34172106 Towards a Method for Cryopreservation of Mosquito Vectors of Human Pathogens Cryobiology. 04, 2021 | Pubmed ID: 33556359 Identification of Mycobacterium Tuberculosis Peptides in Serum Extracellular Vesicles from Persons with Latent Tuberculosis Infection Journal of Clinical Microbiology. 05, 2020 | Pubmed ID: 32245831 Nontuberculous Mycobacteria Show Differential Infectivity and Use Phospholipids to Antagonize LL-37 American Journal of Respiratory Cell and Molecular Biology. 03, 2020 | Pubmed ID: 31545652 Protein Profile of Different Cellular Fractions from Strains After Exposure to Isoniazid Data in Brief. Jun, 2019 | Pubmed ID: 31193076 Mycobacteria and Their Sweet Proteins: An Overview of Protein Glycosylation and Lipoglycosylation in M. Tuberculosis Tuberculosis (Edinburgh, Scotland). 03, 2019 | Pubmed ID: 30948163 Moving Toward Tuberculosis Elimination. Critical Issues for Research in Diagnostics and Therapeutics for Tuberculosis Infection American Journal of Respiratory and Critical Care Medicine. 03, 2019 | Pubmed ID: 30335466 Deciphering the Molecular Basis of Mycobacteria and Lipoglycan Recognition by the C-type Lectin Dectin-2 Scientific Reports. 11, 2018 | Pubmed ID: 30443026 Biochemical Characterization of Isoniazid-resistant Can the Analysis of Clonal Strains Reveal Novel Targetable Pathways? Molecular & Cellular Proteomics : MCP. 09, 2018 | Pubmed ID: 29844232 Structural Determinants in a Glucose-containing Lipopolysaccharide from Critical for Inducing a Subset of Protective T Cells The Journal of Biological Chemistry. 06, 2018 | Pubmed ID: 29716995 Cytokine-Mediated Systemic Adverse Drug Reactions in a Drug-Drug Interaction Study of Dolutegravir with Once-Weekly Isoniazid and Rifapentine Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Feb, 2018 | Pubmed ID: 29415190 The N-terminal Peptide Moiety of the Mycobacterium Tuberculosis 19 KDa Lipoprotein Harbors RP105-agonistic Properties Journal of Leukocyte Biology. Feb, 2018 | Pubmed ID: 29345364 HLA-E Presents Glycopeptides from the Mycobacterium Tuberculosis Protein MPT32 to Human CD8T Cells Scientific Reports. Jul, 2017 | Pubmed ID: 28676677 Second Generation Multiple Reaction Monitoring Assays for Enhanced Detection of Ultra-low Abundancepeptides in Human Serum Clinical Proteomics. 2017 | Pubmed ID: 28592925 Changes in the Membrane-Associated Proteins of Exosomes Released from Human Macrophages After Mycobacterium Tuberculosis Infection Scientific Reports. Nov, 2016 | Pubmed ID: 27897233 Virulence of Mycobacterium Tuberculosis After Acquisition of Isoniazid Resistance: Individual Nature of KatG Mutants and the Possible Role of AhpC PloS One. 2016 | Pubmed ID: 27893795 A Subset of Protective γ9δ2 T Cells Is Activated by Novel Mycobacterial Glycolipid Components Infection and Immunity. 09, 2016 | Pubmed ID: 27297390 Boosting BCG-primed Responses with a Subunit Apa Vaccine During the Waning Phase Improves Immunity and Imparts Protection Against Mycobacterium Tuberculosis Scientific Reports. 05, 2016 | Pubmed ID: 27173443 Longitudinal Whole Genome Analysis of Pre and Post Drug Treatment Mycobacterium Tuberculosis Isolates Reveals Progressive Steps to Drug Resistance Tuberculosis (Edinburgh, Scotland). 05, 2016 | Pubmed ID: 27156618 Comparing Isogenic Strains of Beijing Genotype Mycobacterium Tuberculosis After Acquisition of Isoniazid Resistance: A Proteomics Approach Proteomics. 05, 2016 | Pubmed ID: 26929115 RP105 Engages Phosphatidylinositol 3-Kinase P110δ To Facilitate the Trafficking and Secretion of Cytokines in Macrophages During Mycobacterial Infection Journal of Immunology (Baltimore, Md. : 1950). Oct, 2015 | Pubmed ID: 26371254 Pathogenic Nontuberculous Mycobacteria Resist and Inactivate Cathelicidin: Implication of a Novel Role for Polar Mycobacterial Lipids PloS One. 2015 | Pubmed ID: 25993058 Analysis of the Metabolome of Anopheles Gambiae Mosquito After Exposure to Mycobacterium Ulcerans Scientific Reports. Mar, 2015 | Pubmed ID: 25784490 Fractionation and Analysis of Mycobacterial Proteins Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 25779310 Deciphering the Role of Exosomes in Tuberculosis Tuberculosis (Edinburgh, Scotland). Jan, 2015 | Pubmed ID: 25496995 Detection of Mycobacterium Tuberculosis Peptides in the Exosomes of Patients with Active and Latent M. Tuberculosis Infection Using MRM-MS PloS One. 2014 | Pubmed ID: 25080351 The Human Antibody Response to the Surface of Mycobacterium Tuberculosis PloS One. 2014 | Pubmed ID: 24918450 HspX Vaccination and Role in Virulence in the Guinea Pig Model of Tuberculosis Pathogens and Disease. Aug, 2014 | Pubmed ID: 24616427 Antigen 85 Variation Across Lineages of Mycobacterium Tuberculosis-implications for Vaccine and Biomarker Success Journal of Proteomics. Jan, 2014 | Pubmed ID: 23891556 O-mannosylation of the Mycobacterium Tuberculosis Adhesin Apa is Crucial for T Cell Antigenicity During Infection but is Expendable for Protection PLoS Pathogens. 2013 | Pubmed ID: 24130497 A Chemical Proteomics Approach to Profiling the ATP-binding Proteome of Mycobacterium Tuberculosis Molecular & Cellular Proteomics : MCP. Jun, 2013 | Pubmed ID: 23462205 Autophagy Protects Against Active Tuberculosis by Suppressing Bacterial Burden and Inflammation Proceedings of the National Academy of Sciences of the United States of America. Nov, 2012 | Pubmed ID: 23093667 HspX-mediated Protection Against Tuberculosis Depends on Its Chaperoning of a Mycobacterial Molecule Immunology and Cell Biology. Nov, 2012 | Pubmed ID: 22801575 Purified Protein Derivatives of Tuberculin--past, Present, and Future FEMS Immunology and Medical Microbiology. Dec, 2012 | Pubmed ID: 22762692 Deciphering the Proteome of the in Vivo Diagnostic Reagent "purified Protein Derivative" from Mycobacterium Tuberculosis Proteomics. Apr, 2012 | Pubmed ID: 22522804 Prospective on Mycobacterium Tuberculosis Proteomics Journal of Proteome Research. Jan, 2012 | Pubmed ID: 21988637 Three Protein Cocktails Mediate Delayed-type Hypersensitivity Responses Indistinguishable from That Elicited by Purified Protein Derivative in the Guinea Pig Model of Mycobacterium Tuberculosis Infection Infection and Immunity. Feb, 2011 | Pubmed ID: 21134965 The Non-clonality of Drug Resistance in Beijing-genotype Isolates of Mycobacterium Tuberculosis from the Western Cape of South Africa BMC Genomics. Nov, 2010 | Pubmed ID: 21110864 Portrait of a Pathogen: the Mycobacterium Tuberculosis Proteome in Vivo PloS One. 2010 | Pubmed ID: 21085642 Proteomic Definition of the Cell Wall of Mycobacterium Tuberculosis Journal of Proteome Research. Nov, 2010 | Pubmed ID: 20825248 Proteomic Analysis Identifies Highly Antigenic Proteins in Exosomes from M. Tuberculosis-infected and Culture Filtrate Protein-treated Macrophages Proteomics. Sep, 2010 | Pubmed ID: 20662102 Variation Among Genome Sequences of H37Rv Strains of Mycobacterium Tuberculosis from Multiple Laboratories Journal of Bacteriology. Jul, 2010 | Pubmed ID: 20472797 Descriptive Proteomic Analysis Shows Protein Variability Between Closely Related Clinical Isolates of Mycobacterium Tuberculosis Proteomics. May, 2010 | Pubmed ID: 20217870 A Murine DC-SIGN Homologue Contributes to Early Host Defense Against Mycobacterium Tuberculosis The Journal of Experimental Medicine. Sep, 2009 | Pubmed ID: 19770268 Deciphering the Proteomic Profile of Mycobacterium Leprae Cell Envelope Proteomics. Jun, 2008 | Pubmed ID: 18563741 Conserved Mycobacterial Lipoglycoproteins Activate TLR2 but Also Require Glycosylation for MHC Class II-restricted T Cell Activation Journal of Immunology (Baltimore, Md. : 1950). May, 2008 | Pubmed ID: 18424702 Demonstration of Components of Antigen 85 Complex in Cerebrospinal Fluid of Tuberculous Meningitis Patients Clinical and Diagnostic Laboratory Immunology. Jun, 2005 | Pubmed ID: 15939750 Mycobacterium Tuberculosis Functional Network Analysis by Global Subcellular Protein Profiling Molecular Biology of the Cell. Jan, 2005 | Pubmed ID: 15525680 Continued Proteomic Analysis of Mycobacterium Leprae Subcellular Fractions Proteomics. Oct, 2004 | Pubmed ID: 15378742 A Limited Antigen-specific Cellular Response is Sufficient for the Early Control of Mycobacterium Tuberculosis in the Lung but is Insufficient for Long-term Survival Infection and Immunity. Jul, 2004 | Pubmed ID: 15213116 Proteomic Approaches to Antigen Discovery Methods in Molecular Medicine. 2004 | Pubmed ID: 14959819 Mycobacterium tuberculose Extracellulaire vesikelverrijking door grootte-uitsluitingschromatografie Joan M. Ryan1, Karen M. Dobos1, Nicole A. Kruh-Garcia1,2 1Mycobacteria Research Laboratories, Department of Microbiology Immunology & Pathology, Colorado State University, 2BioMARC, Infectious Disease Research Center, Colorado State University JoVE 63895 Immunology and Infection Vertering van eiwitten, ultrafiltratie en Size Exclusion Chromatography voor het optimaliseren van het isolement van Exosomes uit menselijk bloed Plasma en Serum Gustavo Diaz1, Chandler Bridges1, Megan Lucas1, Yong Cheng2, Jeff S. Schorey2, Karen M. Dobos1, Nicole A. Kruh-Garcia1 1Department of Microbiology, Immunology and Pathology, Colorado State University, 2Department of Biological Sciences, Eck Institute for Global Health, University of Notre Dame JoVE 57467 Biochemistry
Mycobacterium tuberculose Extracellulaire vesikelverrijking door grootte-uitsluitingschromatografie Joan M. Ryan1, Karen M. Dobos1, Nicole A. Kruh-Garcia1,2 1Mycobacteria Research Laboratories, Department of Microbiology Immunology & Pathology, Colorado State University, 2BioMARC, Infectious Disease Research Center, Colorado State University JoVE 63895 Immunology and Infection
Vertering van eiwitten, ultrafiltratie en Size Exclusion Chromatography voor het optimaliseren van het isolement van Exosomes uit menselijk bloed Plasma en Serum Gustavo Diaz1, Chandler Bridges1, Megan Lucas1, Yong Cheng2, Jeff S. Schorey2, Karen M. Dobos1, Nicole A. Kruh-Garcia1 1Department of Microbiology, Immunology and Pathology, Colorado State University, 2Department of Biological Sciences, Eck Institute for Global Health, University of Notre Dame JoVE 57467 Biochemistry
