Karen Ocorr

Publications

• BIN1 is Reduced and Cav1.2 Trafficking is Impaired in Human Failing Cardiomyocytes
  Heart Rhythm : the Official Journal of the Heart Rhythm Society. Dec, 2011  |   Pubmed ID: 22138472
• Over-expression of DSCAM and COL6A2 Cooperatively Generates Congenital Heart Defects
  PLoS Genetics. Nov, 2011  |   Pubmed ID: 22072978
• The UNC-45 Chaperone is Critical for Establishing Myosin-based Myofibrillar Organization and Cardiac Contractility in the Drosophila Heart Model
  PloS One. 2011  |   Pubmed ID: 21799905
• ATP-sensitive Potassium Channel (K(ATP))-dependent Regulation of Cardiotropic Viral Infections
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2011  |   Pubmed ID: 21719711
• Tinman/Nkx2-5 Acts Via MiR-1 and Upstream of Cdc42 to Regulate Heart Function Across Species
  The Journal of Cell Biology. Jun, 2011  |   Pubmed ID: 21690310
• Cloning and Characterization of the Cardiac-specific Lrrc10 Promoter
  BMB Reports. Feb, 2011  |   Pubmed ID: 21345312
• Phospholipid Homeostasis Regulates Lipid Metabolism and Cardiac Function Through SREBP Signaling in Drosophila
  Genes & Development. Jan, 2011  |   Pubmed ID: 21245170
• Drosophila As a Model to Study Cardiac Aging
  Experimental Gerontology. May, 2011  |   Pubmed ID: 21130861
• The Effect of Excess Expression of GFP in a Novel Heart-specific Green Fluorescence Zebrafish Regulated by Nppa Enhancer at Early Embryonic Development
  Molecular Biology Reports. Feb, 2011  |   Pubmed ID: 20383585
• High-fat-diet-induced Obesity and Heart Dysfunction Are Regulated by the TOR Pathway in Drosophila
  Cell Metabolism. Nov, 2010  |   Pubmed ID: 21035763
• SAMD4B, a Novel SAM-containing Protein, Inhibits AP-1-, P53- and P21-mediated Transcriptional Activity
  BMB Reports. May, 2010  |   Pubmed ID: 20510020
• A Global in Vivo Drosophila RNAi Screen Identifies NOT3 As a Conserved Regulator of Heart Function
  Cell. Apr, 2010  |   Pubmed ID: 20371351
• Sestrin As a Feedback Inhibitor of TOR That Prevents Age-related Pathologies
  Science (New York, N.Y.). Mar, 2010  |   Pubmed ID: 20203043
• KBTBD7, a Novel Human BTB-kelch Protein, Activates Transcriptional Activities of SRE and AP-1
  BMB Reports. Jan, 2010  |   Pubmed ID: 20132730
• Drug Discovery Through Functional Screening in the Drosophila Heart
  Methods in Molecular Biology (Clifton, N.J.). 2009  |   Pubmed ID: 19718521
• Heterozygous Mutation of Drosophila Opa1 Causes the Development of Multiple Organ Abnormalities in an Age-dependent and Organ-specific Manner
  PloS One. 2009  |   Pubmed ID: 19718456
• D4eBP Acts Downstream of Both DTOR and DFoxo to Modulate Cardiac Functional Aging in Drosophila
  Aging Cell. Sep, 2009  |   Pubmed ID: 19594484
• A New Method for Detection and Quantification of Heartbeat Parameters in Drosophila, Zebrafish, and Embryonic Mouse Hearts
  BioTechniques. Feb, 2009  |   Pubmed ID: 19317655
• Non-autonomous Modulation of Heart Rhythm, Contractility and Morphology in Adult Fruit Flies
  Developmental Biology. Apr, 2009  |   Pubmed ID: 19233157
• Transcription Factor Neuromancer/TBX20 is Required for Cardiac Function in Drosophila with Implications for Human Heart Disease
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2008  |   Pubmed ID: 19074289
• A Novel Human BTB-kelch Protein KLHL31, Strongly Expressed in Muscle and Heart, Inhibits Transcriptional Activities of TRE and SRE
  Molecules and Cells. Nov, 2008  |   Pubmed ID: 18719355
• Dystrophin Deficiency in Drosophila Reduces Lifespan and Causes a Dilated Cardiomyopathy Phenotype
  Aging Cell. Mar, 2008  |   Pubmed ID: 18221418
• ZNF418, a Novel Human KRAB/C2H2 Zinc Finger Protein, Suppresses MAPK Signaling Pathway
  Molecular and Cellular Biochemistry. Mar, 2008  |   Pubmed ID: 18084723
• The Drosophila Muscle LIM Protein, Mlp84B, is Essential for Cardiac Function
  The Journal of Experimental Biology. Jan, 2008  |   Pubmed ID: 18083727
• Drosophila Aging 2006/2007
  Experimental Gerontology. Jan, 2008  |   Pubmed ID: 18061385
• Myosin Transducer Mutations Differentially Affect Motor Function, Myofibril Structure, and the Performance of Skeletal and Cardiac Muscles
  Molecular Biology of the Cell. Feb, 2008  |   Pubmed ID: 18045988
• ZNF307, a Novel Zinc Finger Gene Suppresses P53 and P21 Pathway
  Biochemical and Biophysical Research Communications. Nov, 2007  |   Pubmed ID: 17910948
• Genetic Variation for Cardiac Dysfunction in Drosophila
  PloS One. 2007  |   Pubmed ID: 17622346
• Genetic Control of Heart Function and Aging in Drosophila
  Trends in Cardiovascular Medicine. Jul, 2007  |   Pubmed ID: 17574126
• KCNQ Potassium Channel Mutations Cause Cardiac Arrhythmias in Drosophila That Mimic the Effects of Aging
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2007  |   Pubmed ID: 17360457
• Age-related Cardiac Disease Model of Drosophila
  Mechanisms of Ageing and Development. Jan, 2007  |   Pubmed ID: 17125816
• The ATP-sensitive Potassium (KATP) Channel-encoded DSUR Gene is Required for Drosophila Heart Function and is Regulated by Tinman
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006  |   Pubmed ID: 16882722