Karl E. Griswold Thayer School of Engineering Dartmouth College Biography Publications Institution JoVE Articles Karl E. Griswold has not added a biography. If you are Karl E. Griswold and would like to personalize this page please email our Author Liaison for assistance. Publications Bioengineered Lysozyme in Combination Therapies for Pseudomonas Aeruginosa Lung Infections Bioengineered. Feb, 2014 | Pubmed ID: 24637705 Gene and Protein Sequence Optimization for High Level Production of Fully Active and Aglycosylated Lysostaphin in Pichia Pastoris Applied and Environmental Microbiology. Feb, 2014 | Pubmed ID: 24561590 Bioengineered Lysozyme Reduces Bacterial Burden and Inflammation in a Murine Model of Mucoid Pseudomonas Aeruginosa Lung Infection Antimicrobial Agents and Chemotherapy. Nov, 2013 | Pubmed ID: 23979752 A High-throughput Screen for Antibiotic Drug Discovery Biotechnology and Bioengineering. Aug, 2013 | Pubmed ID: 23955804 Molecular Sensing with Magnetic Nanoparticles Using Magnetic Spectroscopy of Nanoparticle Brownian Motion Biosensors & Bioelectronics. Dec, 2013 | Pubmed ID: 23896525 Structure-guided Deimmunization of Therapeutic Proteins Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. Feb, 2013 | Pubmed ID: 23384000 Structure-based Redesign of Proteins for Minimal T-cell Epitope Content Journal of Computational Chemistry. Apr, 2013 | Pubmed ID: 23299435 Engineering Escherichia Coli for Soluble Expression and Single Step Purification of Active Human Lysozyme Journal of Biotechnology. Mar, 2013 | Pubmed ID: 23220215 Alginate Lyase Exhibits Catalysis-independent Biofilm Dispersion and Antibiotic Synergy Antimicrobial Agents and Chemotherapy. Jan, 2013 | Pubmed ID: 23070175 Design and Analysis of Immune-evading Enzymes for ADEPT Therapy Protein Engineering, Design & Selection : PEDS. Oct, 2012 | Pubmed ID: 22898588 Optimization of Combinatorial Mutagenesis Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. Nov, 2011 | Pubmed ID: 21923411 Optimization of Therapeutic Proteins to Delete T-cell Epitopes While Maintaining Beneficial Residue Interactions Journal of Bioinformatics and Computational Biology. Apr, 2011 | Pubmed ID: 21523929 Crystal Structure of a Charge Engineered Human Lysozyme Having Enhanced Bactericidal Activity PloS One. 2011 | Pubmed ID: 21408218 Genetically Engineered Alginate Lyase-PEG Conjugates Exhibit Enhanced Catalytic Function and Reduced Immunoreactivity PloS One. 2011 | Pubmed ID: 21340021 The Monoclonal Myth Bioengineered Bugs. May-Jun, 2010 | Pubmed ID: 21326931 Enhanced Antimicrobial Activity of Engineered Human Lysozyme ACS Chemical Biology. Sep, 2010 | Pubmed ID: 20604527 Optimization Algorithms for Functional Deimmunization of Therapeutic Proteins BMC Bioinformatics. 2010 | Pubmed ID: 20380721 Protein Fragment Swapping: a Method for Asymmetric, Selective Site-directed Recombination Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. Mar, 2010 | Pubmed ID: 20377457 Quantifying and Resolving Multiple Vector Transformants in S. Cerevisiae Plasmid Libraries BMC Biotechnology. 2009 | Pubmed ID: 19930565 The Evolution of Catalytic Efficiency and Substrate Promiscuity in Human Theta Class 1-1 Glutathione Transferase Journal of Molecular Biology. Dec, 2006 | Pubmed ID: 17011574 Direct Selection of Trans-acting Ligase Ribozymes by in Vitro Compartmentalization RNA (New York, N.Y.). Oct, 2005 | Pubmed ID: 16131588 Evolution of Highly Active Enzymes by Homology-independent Recombination Proceedings of the National Academy of Sciences of the United States of America. Jul, 2005 | Pubmed ID: 16009931 Enhanced Crossover SCRATCHY: Construction and High-throughput Screening of a Combinatorial Library Containing Multiple Non-homologous Crossovers Nucleic Acids Research. Nov, 2003 | Pubmed ID: 14576326 PH Sensing Agar Plate Assays for Esterolytic Enzyme Activity Methods in Molecular Biology (Clifton, N.J.). 2003 | Pubmed ID: 12824584 Effects of Codon Usage Versus Putative 5'-mRNA Structure on the Expression of Fusarium Solani Cutinase in the Escherichia Coli Cytoplasm Protein Expression and Purification. Jan, 2003 | Pubmed ID: 12509995 En hög genomströmning MHC II-bindningsanalys för kvantitativ analys av peptidepitoper Regina Salvat1, Leonard Moise2, Chris Bailey-Kellogg3, Karl E. Griswold1 1Thayer School of Engineering, Dartmouth College, 2Institute for Immunology and Informatics, University of Rhode Island, 3Department of Computer Science, Dartmouth College JoVE 51308 Biology
En hög genomströmning MHC II-bindningsanalys för kvantitativ analys av peptidepitoper Regina Salvat1, Leonard Moise2, Chris Bailey-Kellogg3, Karl E. Griswold1 1Thayer School of Engineering, Dartmouth College, 2Institute for Immunology and Informatics, University of Rhode Island, 3Department of Computer Science, Dartmouth College JoVE 51308 Biology