Katarina Stoklund Dittlau Laboratory of Neurobiology VIB-KU Leuven Center for Brain and Disease Research Biography Publications Institution JoVE Articles Katarina Stoklund Dittlau Katarina Stoklund Dittlau is a doctoral researcher in the Laboratory of Neurobiology at the VIB-KU Leuven Center for Brain and Disease Research. In the group of Prof. Dr. Ludo Van Den Bosch, Katarina uses human induced pluripotent stem cells (hiPSCs) to investigate the molecular mechanisms of motor neuron disorder amyotrophic lateral sclerosis (ALS). During her PhD, Katarina has developed a new model, which combines hiPSC-derived motor neurons with human muscle cells in microfluidic devices in the formation of functional human neuromuscular junctions. Using this model, her research focuses on the familial form of ALS caused by mutations in the FUS gene.Katarina is a veterinarian and received her Doctor of Veterinary Medicine (DVM) degree in 2018 from University of Copenhagen, Denmark. Publications Human Motor Units in Microfluidic Devices Are Impaired by FUS Mutations and Improved by HDAC6 Inhibition Stem Cell Reports. Apr, 2021 | Pubmed ID: 33891869 Axonal Transport Defects and Neurodegeneration: Molecular Mechanisms and Therapeutic Implications Seminars in Cell & Developmental Biology. 03, 2020 | Pubmed ID: 31542222 Oocytes, Embryos and Pluripotent Stem Cells from a Biomedical Perspective Animal Reproduction. Oct, 2019 | Pubmed ID: 32435294 Generering av mänskliga motorenheter med funktionella neuromuskulära korsningar i mikrofluidiska enheter Katarina Stoklund Dittlau1,2, Emily N. Krasnow1,2, Laura Fumagalli1,2, Tijs Vandoorne1,2, Pieter Baatsen3,4, Axelle Kerstens3,4, Giorgia Giacomazzi5, Benjamin Pavie3,4, Elisabeth Rossaert1,2, Jimmy Beckers1,2, Maurilio Sampaolesi5, Philip Van Damme1,2,6, Ludo Van Den Bosch1,2 1Department of Neurosciences, Experimental Neurology, and Leuven Brain Institute, KU Leuven - University of Leuven, 2VIB Center for Brain & Disease Research, Laboratory of Neurobiology, , 3VIB Center for Brain & Disease Research, Research Group Molecular Neurobiology, , 4VIB Bio Imaging Core, KU Leuven - University of Leuven, 5Department of Development and Regeneration, Stem Cell and Developmental Biology, KU Leuven - University of Leuven, 6Department of Neurology, University Hospitals Leuven JoVE 62959 Neuroscience
Generering av mänskliga motorenheter med funktionella neuromuskulära korsningar i mikrofluidiska enheter Katarina Stoklund Dittlau1,2, Emily N. Krasnow1,2, Laura Fumagalli1,2, Tijs Vandoorne1,2, Pieter Baatsen3,4, Axelle Kerstens3,4, Giorgia Giacomazzi5, Benjamin Pavie3,4, Elisabeth Rossaert1,2, Jimmy Beckers1,2, Maurilio Sampaolesi5, Philip Van Damme1,2,6, Ludo Van Den Bosch1,2 1Department of Neurosciences, Experimental Neurology, and Leuven Brain Institute, KU Leuven - University of Leuven, 2VIB Center for Brain & Disease Research, Laboratory of Neurobiology, , 3VIB Center for Brain & Disease Research, Research Group Molecular Neurobiology, , 4VIB Bio Imaging Core, KU Leuven - University of Leuven, 5Department of Development and Regeneration, Stem Cell and Developmental Biology, KU Leuven - University of Leuven, 6Department of Neurology, University Hospitals Leuven JoVE 62959 Neuroscience
