Other Publications (1)
Articles by Keely A. Heintz in JoVE
Image-guided, Laser-based Fabrication of Vascular-derived Microfluidic Networks Keely A. Heintz1, David Mayerich2, John H. Slater1,3 1Department of Biomedical Engineering, University of Delaware, 2Department of Electrical and Computer Engineering, University of Houston, 3Delaware Biotechnology Institute This protocol outlines the implementation of image-guided, laser-based hydrogel degradation to fabricate vascular-derived, biomimetic microfluidic networks embedded in poly(ethylene glycol) diacrylate (PEGDA) hydrogels. These biomimetic microfluidic systems may be useful for tissue engineering applications, generation of in vitro disease models, and fabrication of advanced "on-a-chip" devices.
Other articles by Keely A. Heintz on PubMed
Fabrication of 3D Biomimetic Microfluidic Networks in Hydrogels Advanced Healthcare Materials. Sep, 2016 | Pubmed ID: 27239785 A laser-based hydrogel degradation technique is developed that allows for local control over hydrogel porosity, fabrication of 3D vascular-derived, biomimetic, hydrogel-embedded microfluidic networks, and generation of two intertwining, yet independent, microfluidic networks in a single construct.