Keizo Takao Japan Science and Technology Agency Core Research for Evolutionary Science and Technology (CREST) Biography Publications Institution JoVE Articles Keizo Takao has not added a biography. If you are Keizo Takao and would like to personalize this page please email our Author Liaison for assistance. Publications Reply to Warren Et Al. and Shay Et Al.: Commonalities Across Species Do Exist and Are Potentially Important Proceedings of the National Academy of Sciences of the United States of America. Jan, 2015 | Pubmed ID: 25540421 Genomic Responses in Mouse Models Greatly Mimic Human Inflammatory Diseases Proceedings of the National Academy of Sciences of the United States of America. Jan, 2015 | Pubmed ID: 25092317 IL1RAPL1 Knockout Mice Show Spine Density Decrease, Learning Deficiency, Hyperactivity and Reduced Anxiety-like Behaviours Scientific Reports. 2014 | Pubmed ID: 25312502 SIRT1 Overexpression Ameliorates a Mouse Model of SOD1-linked Amyotrophic Lateral Sclerosis Via HSF1/HSP70i Chaperone System Molecular Brain. 2014 | Pubmed ID: 25167838 [Immaturity of Brain As an Endophenotype of Neuropsychiatric Disorders] Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. Jun, 2014 | Pubmed ID: 25076776 Mechanisms for Interferon-α-induced Depression and Neural Stem Cell Dysfunction Stem Cell Reports. Jul, 2014 | Pubmed ID: 25068123 Enhanced Stability of Hippocampal Place Representation Caused by Reduced Magnesium Block of NMDA Receptors in the Dentate Gyrus Molecular Brain. 2014 | Pubmed ID: 24893573 Transcriptomic Evidence for Immaturity of the Prefrontal Cortex in Patients with Schizophrenia Molecular Brain. 2014 | Pubmed ID: 24886351 Comprehensive Behavioral Study of MGluR3 Knockout Mice: Implication in Schizophrenia Related Endophenotypes Molecular Brain. 2014 | Pubmed ID: 24758191 Targeted Deletion of the C-terminus of the Mouse Adenomatous Polyposis Coli Tumor Suppressor Results in Neurologic Phenotypes Related to Schizophrenia Molecular Brain. 2014 | Pubmed ID: 24678719 Comprehensive Behavioral Analysis of Cluster of Differentiation 47 Knockout Mice PloS One. 2014 | Pubmed ID: 24586890 Absence of BRINP1 in Mice Causes Increase of Hippocampal Neurogenesis and Behavioral Alterations Relevant to Human Psychiatric Disorders Molecular Brain. 2014 | Pubmed ID: 24528488 Mice Lacking Collapsin Response Mediator Protein 1 Manifest Hyperactivity, Impaired Learning and Memory, and Impaired Prepulse Inhibition Frontiers in Behavioral Neuroscience. 2013 | Pubmed ID: 24409129 PRICKLE1 Interaction with SYNAPSIN I Reveals a Role in Autism Spectrum Disorders PloS One. 2013 | Pubmed ID: 24312498 Point Mutation in Syntaxin-1A Causes Abnormal Vesicle Recycling, Behaviors, and Short Term Plasticity The Journal of Biological Chemistry. Nov, 2013 | Pubmed ID: 24136198 Chronic Overload of SEPT4, a Parkin Substrate That Aggregates in Parkinson's Disease, Causes Behavioral Alterations but Not Neurodegeneration in Mice Molecular Brain. 2013 | Pubmed ID: 23938054 Immature Dentate Gyrus: an Endophenotype of Neuropsychiatric Disorders Neural Plasticity. 2013 | Pubmed ID: 23840971 ENU-mutagenesis Mice with a Non-synonymous Mutation in Grin1 Exhibit Abnormal Anxiety-like Behaviors, Impaired Fear Memory, and Decreased Acoustic Startle Response BMC Research Notes. 2013 | Pubmed ID: 23688147 Synaptosomal-associated Protein 25 Mutation Induces Immaturity of the Dentate Granule Cells of Adult Mice Molecular Brain. 2013 | Pubmed ID: 23497716 Post-natal Treatment by a Blood-brain-barrier Permeable Calpain Inhibitor, SNJ1945 Rescued Defective Function in Lissencephaly Scientific Reports. 2013 | Pubmed ID: 23390575 Deficiency of Schnurri-2, an MHC Enhancer Binding Protein, Induces Mild Chronic Inflammation in the Brain and Confers Molecular, Neuronal, and Behavioral Phenotypes Related to Schizophrenia Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Jul, 2013 | Pubmed ID: 23389689 Increased Astrocytic ATP Release Results in Enhanced Excitability of the Hippocampus Glia. Feb, 2013 | Pubmed ID: 23018918 Behavioral Abnormalities Observed in Zfhx2-deficient Mice PloS One. 2012 | Pubmed ID: 23300874 Impaired Synaptic Clustering of Postsynaptic Density Proteins and Altered Signal Transmission in Hippocampal Neurons, and Disrupted Learning Behavior in PDZ1 and PDZ2 Ligand Binding-deficient PSD-95 Knockin Mice Molecular Brain. 2012 | Pubmed ID: 23268962 Comprehensive Behavioral Analysis of Pituitary Adenylate Cyclase-activating Polypeptide (PACAP) Knockout Mice Frontiers in Behavioral Neuroscience. 2012 | Pubmed ID: 23060763 DRPLA Transgenic Mouse Substrains Carrying Single Copy of Full-length Mutant Human DRPLA Gene with Variable Sizes of Expanded CAG Repeats Exhibit CAG Repeat Length- and Age-dependent Changes in Behavioral Abnormalities and Gene Expression Profiles Neurobiology of Disease. Feb, 2012 | Pubmed ID: 22342974 Adenomatous Polyposis Coli Heterozygous Knockout Mice Display Hypoactivity and Age-dependent Working Memory Deficits Frontiers in Behavioral Neuroscience. 2011 | Pubmed ID: 22347851 DIP/WISH Deficiency Enhances Synaptic Function and Performance in the Barnes Maze Molecular Brain. 2011 | Pubmed ID: 22018352 Relaxin-3-deficient Mice Showed Slight Alteration in Anxiety-related Behavior Frontiers in Behavioral Neuroscience. 2011 | Pubmed ID: 21887138 P301S Mutant Human Tau Transgenic Mice Manifest Early Symptoms of Human Tauopathies with Dementia and Altered Sensorimotor Gating PloS One. 2011 | Pubmed ID: 21698260 Forebrain-specific Constitutively Active CaMKKα Transgenic Mice Show Deficits in Hippocampus-dependent Long-term Memory Neurobiology of Learning and Memory. Sep, 2011 | Pubmed ID: 21558011 Synaptic E3 Ligase SCRAPPER in Contextual Fear Conditioning: Extensive Behavioral Phenotyping of Scrapper Heterozygote and Overexpressing Mutant Mice PloS One. 2011 | Pubmed ID: 21390313 The Influence of Chronic Cerebral Hypoperfusion on Cognitive Function and Amyloid β Metabolism in APP Overexpressing Mice PloS One. 2011 | Pubmed ID: 21305033 Inactivation of Fibroblast Growth Factor Binding Protein 3 Causes Anxiety-related Behaviors Molecular and Cellular Neurosciences. Jan, 2011 | Pubmed ID: 20851768 Decreased Exploratory Activity in a Mouse Model of 15q Duplication Syndrome; Implications for Disturbance of Serotonin Signaling PloS One. 2010 | Pubmed ID: 21179543 Expression of Tryptophan 2,3-dioxygenase in Mature Granule Cells of the Adult Mouse Dentate Gyrus Molecular Brain. 2010 | Pubmed ID: 20815922 Stress-evoked Tyrosine Phosphorylation of Signal Regulatory Protein α Regulates Behavioral Immobility in the Forced Swim Test The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2010 | Pubmed ID: 20685990 Behavioral Profiles of Three C57BL/6 Substrains Frontiers in Behavioral Neuroscience. 2010 | Pubmed ID: 20676234 [Immature Dentate Gyrus As a Candidate Endophenotype of Psychiatric Disorders] Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. Jun, 2010 | Pubmed ID: 20666142 Comprehensive Behavioral Analysis of Calcium/calmodulin-dependent Protein Kinase IV Knockout Mice PloS One. 2010 | Pubmed ID: 20209163 SDOP-DB: a Comparative Standardized-protocol Database for Mouse Phenotypic Analyses Bioinformatics (Oxford, England). Apr, 2010 | Pubmed ID: 20194625 Nardilysin Regulates Axonal Maturation and Myelination in the Central and Peripheral Nervous System Nature Neuroscience. Dec, 2009 | Pubmed ID: 19935654 Abnormalities in Brain Structure and Behavior in GSK-3alpha Mutant Mice Molecular Brain. 2009 | Pubmed ID: 19925672 KF-1 Ubiquitin Ligase: An Anxiety Suppressor Frontiers in Neuroscience. May, 2009 | Pubmed ID: 19753093 Neural Activity Changes Underlying the Working Memory Deficit in Alpha-CaMKII Heterozygous Knockout Mice Frontiers in Behavioral Neuroscience. 2009 | Pubmed ID: 19750198 Inhibition of Calpain Increases LIS1 Expression and Partially Rescues in Vivo Phenotypes in a Mouse Model of Lissencephaly Nature Medicine. Oct, 2009 | Pubmed ID: 19734909 Intrauterine Environment-genome Interaction and Children's Development (4): Brain-behavior Phenotypying of Genetically-engineered Mice Using a Comprehensive Behavioral Test Battery on Research of Neuropsychiatric Disorders The Journal of Toxicological Sciences. 2009 | Pubmed ID: 19571483 Mice with Altered Myelin Proteolipid Protein Gene Expression Display Cognitive Deficits Accompanied by Abnormal Neuron-glia Interactions and Decreased Conduction Velocities The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2009 | Pubmed ID: 19571127 Abnormal Behavior in a Chromosome-engineered Mouse Model for Human 15q11-13 Duplication Seen in Autism Cell. Jun, 2009 | Pubmed ID: 19563756 Abnormal Social Behavior, Hyperactivity, Impaired Remote Spatial Memory, and Increased D1-mediated Dopaminergic Signaling in Neuronal Nitric Oxide Synthase Knockout Mice Molecular Brain. 2009 | Pubmed ID: 19538708 Comprehensive Behavioral Phenotyping of Ryanodine Receptor Type 3 (RyR3) Knockout Mice: Decreased Social Contact Duration in Two Social Interaction Tests Frontiers in Behavioral Neuroscience. 2009 | Pubmed ID: 19503748 [Genes, Behaviors and Psychiatric Disorders] Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. Mar, 2008 | Pubmed ID: 21089339 Normal Mitochondrial Respiratory Function is Essential for Spatial Remote Memory in Mice Molecular Brain. 2008 | Pubmed ID: 19087269 Mice Lacking the Kf-1 Gene Exhibit Increased Anxiety- but Not Despair-like Behavior Frontiers in Behavioral Neuroscience. 2008 | Pubmed ID: 18958194 Impaired Long-term Memory Retention and Working Memory in Sdy Mutant Mice with a Deletion in Dtnbp1, a Susceptibility Gene for Schizophrenia Molecular Brain. 2008 | Pubmed ID: 18945333 Comprehensive Behavioral Phenotyping of Calpastatin-knockout Mice Molecular Brain. 2008 | Pubmed ID: 18803809 Alpha-CaMKII Deficiency Causes Immature Dentate Gyrus, a Novel Candidate Endophenotype of Psychiatric Disorders Molecular Brain. 2008 | Pubmed ID: 18803808 Roles of Continuous Neurogenesis in the Structural and Functional Integrity of the Adult Forebrain Nature Neuroscience. Oct, 2008 | Pubmed ID: 18758458 Identification of YWHAE, a Gene Encoding 14-3-3epsilon, As a Possible Susceptibility Gene for Schizophrenia Human Molecular Genetics. Oct, 2008 | Pubmed ID: 18658164 [Investigating Genes-to-behavior Pathways in Psychiatric Diseases: an Approach Using a Comprehensive Behavioral Test Battery on Genetically Engineered Mice] Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. Jun, 2008 | Pubmed ID: 18646600 Genetic Ablation of NMDA Receptor Subunit NR3B in Mouse Reveals Motoneuronal and Nonmotoneuronal Phenotypes The European Journal of Neuroscience. Sep, 2007 | Pubmed ID: 17880385 Impact of Brain-behavior Phenotypying of Genetically-engineered Mice on Research of Neuropsychiatric Disorders Neuroscience Research. Jun, 2007 | Pubmed ID: 17524507 Investigating Gene-to-behavior Pathways in Psychiatric Disorders: the Use of a Comprehensive Behavioral Test Battery on Genetically Engineered Mice Annals of the New York Academy of Sciences. Nov, 2006 | Pubmed ID: 17185513 Targeting Quantum Dots to Surface Proteins in Living Cells with Biotin Ligase Proceedings of the National Academy of Sciences of the United States of America. May, 2005 | Pubmed ID: 15897449 Visualization of Synaptic Ca2+ /calmodulin-dependent Protein Kinase II Activity in Living Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2005 | Pubmed ID: 15788767 Ionic Basis of Cold Receptors Acting As Thermostats The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2002 | Pubmed ID: 12019319 Contextuele en cued Fear Conditioning Test Met behulp van een video analysesysteem in Muizen Hirotaka Shoji1,2, Keizo Takao2,3, Satoko Hattori1,2, Tsuyoshi Miyakawa1,2,3 1Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, 2Japan Science and Technology Agency, Core Research for Evolutionary Science and Technology (CREST), 3Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, National Institutes of Natural Sciences JoVE 50871 Behavior T-doolhof Gedwongen Afwisseling en links-rechts Discriminatie Taken voor de beoordeling van Werken en Reference geheugen in Muizen Hirotaka Shoji1,2, Hideo Hagihara1, Keizo Takao3, Satoko Hattori1,2,3, Tsuyoshi Miyakawa1,2,3 1Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, 2Japan Science and Technology Agency, Core Research for Evolutionary Science and Technology (CREST), 3Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, National Institutes of Natural Sciences JoVE 3300 Neuroscience Verhoogd Plus Maze voor muizen Munekazu Komada1, Keizo Takao1,2, Tsuyoshi Miyakawa2 1Genetic Engineering and Functional Genomics Unit, Frontier Technology Center, Graduate School of Medicine, Kyoto University, 2Institute for Comprehensive Medical Science Division of Systems Medicine, Fujita Health University JoVE 1088 Biology Licht / donker Overgang test voor Muizen Keizo Takao1, Tsuyoshi Miyakawa1 1Genetic Engineering and Functional Genomics Unit, Horizontal Medical Research Organization, Graduate School of Medicine, Kyoto University JoVE 104 Biology
Contextuele en cued Fear Conditioning Test Met behulp van een video analysesysteem in Muizen Hirotaka Shoji1,2, Keizo Takao2,3, Satoko Hattori1,2, Tsuyoshi Miyakawa1,2,3 1Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, 2Japan Science and Technology Agency, Core Research for Evolutionary Science and Technology (CREST), 3Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, National Institutes of Natural Sciences JoVE 50871 Behavior
T-doolhof Gedwongen Afwisseling en links-rechts Discriminatie Taken voor de beoordeling van Werken en Reference geheugen in Muizen Hirotaka Shoji1,2, Hideo Hagihara1, Keizo Takao3, Satoko Hattori1,2,3, Tsuyoshi Miyakawa1,2,3 1Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, 2Japan Science and Technology Agency, Core Research for Evolutionary Science and Technology (CREST), 3Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, National Institutes of Natural Sciences JoVE 3300 Neuroscience
Verhoogd Plus Maze voor muizen Munekazu Komada1, Keizo Takao1,2, Tsuyoshi Miyakawa2 1Genetic Engineering and Functional Genomics Unit, Frontier Technology Center, Graduate School of Medicine, Kyoto University, 2Institute for Comprehensive Medical Science Division of Systems Medicine, Fujita Health University JoVE 1088 Biology
Licht / donker Overgang test voor Muizen Keizo Takao1, Tsuyoshi Miyakawa1 1Genetic Engineering and Functional Genomics Unit, Horizontal Medical Research Organization, Graduate School of Medicine, Kyoto University JoVE 104 Biology
