Kelly M. McNagny

Publications

• HDAC2 Regulates Site-Specific Acetylation of MDM2 and Its Ubiquitination Signaling in Tumor Suppression
  IScience. Mar, 2019   |   Pubmed ID: 30818224
• Podocalyxin is Required for Maintaining Blood-brain Barrier Function During Acute Inflammation
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2019   |   Pubmed ID: 30787191
• The First Identified Heterozygous Nonsense Mutations in Podocalyxin Offer New Perspectives on the Biology of Podocytopathies
  Clinical Science (London, England : 1979). Feb, 2019   |   Pubmed ID: 30737302
• IL-22 Preserves Gut Epithelial Integrity and Promotes Disease Remission During Chronic Infection
  Journal of Immunology (Baltimore, Md. : 1950). Feb, 2019   |   Pubmed ID: 30617224
• Mast Cells Promote Small Bowel Cancer in a Tumor Stage-specific and Cytokine-dependent Manner
  Proceedings of the National Academy of Sciences of the United States of America. 02, 2018   |   Pubmed ID: 29429965
• The Sialidase (Kdnase) Contributes to Cell Wall Integrity and Virulence in Amphotericin B-Treated Mice
  Frontiers in Microbiology. Month, 2017   |   Pubmed ID: 29403452
• Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development
  Stem Cells (Dayton, Ohio). 12, 2017   |   Pubmed ID: 28905451
• Loss of Vascular CD34 Results in Increased Sensitivity to Lung Injury
  American Journal of Respiratory Cell and Molecular Biology. 12, 2017   |   Pubmed ID: 28683207
• Induces a Type IV Hypersensitivity Response in a Mouse Model of Airway Inflammation
  Physiological Reports. Apr, 2017   |   Pubmed ID: 28364028
• Protein Interaction Screening Identifies SH3RF1 As a New Regulator of FAT1 Protein Levels
  FEBS Letters. Feb, 2017   |   Pubmed ID: 28129444
• The Orphan Nuclear Receptor RORα and Group 3 Innate Lymphoid Cells Drive Fibrosis in a Mouse Model of Crohn's Disease
  Science Immunology. Sep, 2016   |   Pubmed ID: 28783681
• The Orphan Nuclear Receptor ROR Alpha and Group 3 Innate Lymphoid Cells Drive Fibrosis in a Mouse Model of Crohn's Disease
  Science Immunology. Sep, 2016   |   Pubmed ID: 28670633
• Chronic Trichuris Muris Infection Alters Hematopoiesis and Causes IFN-γ-expressing T-cell Accumulation in the Mouse Bone Marrow
  European Journal of Immunology. 11, 2016   |   Pubmed ID: 27594558
• CD34 Promotes Pathological Epi-Retinal Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy
  PloS One. Month, 2016   |   Pubmed ID: 27352134
• G9a Regulates Group 2 Innate Lymphoid Cell Development by Repressing the Group 3 Innate Lymphoid Cell Program
  The Journal of Experimental Medicine. 06, 2016   |   Pubmed ID: 27298444
• SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling
  Developmental Cell. Apr, 2016   |   Pubmed ID: 27046831
• DMSO Represses Inflammatory Cytokine Production from Human Blood Cells and Reduces Autoimmune Arthritis
  PloS One. Month, 2016   |   Pubmed ID: 27031833
• Impact of a CXCL12/CXCR4 Antagonist in Bleomycin (BLM) Induced Pulmonary Fibrosis and Carbon Tetrachloride (CCl4) Induced Hepatic Fibrosis in Mice
  PloS One. Month, 2016   |   Pubmed ID: 26998906
• The Cell Surface Mucin Podocalyxin Regulates Collective Breast Tumor Budding
  Breast Cancer Research : BCR. Jan, 2016   |   Pubmed ID: 26796961
• Morphometric Analysis of Inflammation in Bronchial Biopsies Following Exposure to Inhaled Diesel Exhaust and Allergen Challenge in Atopic Subjects
  Particle and Fibre Toxicology. Jan, 2016   |   Pubmed ID: 26758251
• Dendritic-cell Expression of Ship1 Regulates Th2 Immunity to Helminth Infection in Mice
  European Journal of Immunology. Jan, 2016   |   Pubmed ID: 26518471
• Modelling Kidney Disease with CRISPR-mutant Kidney Organoids Derived from Human Pluripotent Epiblast Spheroids
  Nature Communications. Oct, 2015   |   Pubmed ID: 26493500
• Early Infancy Microbial and Metabolic Alterations Affect Risk of Childhood Asthma
  Science Translational Medicine. Sep, 2015   |   Pubmed ID: 26424567
• Podocalyxin Enhances Breast Tumor Growth and Metastasis and is a Target for Monoclonal Antibody Therapy
  Breast Cancer Research : BCR. Mar, 2015   |   Pubmed ID: 25887862
• Lineage-specific Regulation of Allergic Airway Inflammation by the Lipid Phosphatase Src Homology 2 Domain-containing Inositol 5-phosphatase (SHIP-1)
  The Journal of Allergy and Clinical Immunology. Sep, 2015   |   Pubmed ID: 25746967
• Pulmonary CD103 Expression Regulates Airway Inflammation in Asthma
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Apr, 2015   |   Pubmed ID: 25681437
• Mast Cells in Human Health and Disease
  Methods in Molecular Biology (Clifton, N.J.). Month, 2015   |   Pubmed ID: 25388247
• Perinatal Antibiotic-induced Shifts in Gut Microbiota Have Differential Effects on Inflammatory Lung Diseases
  The Journal of Allergy and Clinical Immunology. Jan, 2015   |   Pubmed ID: 25145536
• Podocalyxin Regulates Murine Lung Vascular Permeability by Altering Endothelial Cell Adhesion
  PloS One. Month, 2014   |   Pubmed ID: 25303643
• Perinatal Immunization With Vaccine-Grade Listeria Monocytogenes Provides Protection Against Murine Th2 Airway Inflammation
  Allergy, Asthma & Immunology Research. Jul, 2014   |   Pubmed ID: 24991458
• Group 2 Innate Lymphoid Cells Facilitate Sensitization to Local, but Not Systemic, TH2-inducing Allergen Exposures
  The Journal of Allergy and Clinical Immunology. Apr, 2014   |   Pubmed ID: 24679471
• Methyltransferase G9A Regulates T Cell Differentiation During Murine Intestinal Inflammation
  The Journal of Clinical Investigation. May, 2014   |   Pubmed ID: 24667637
• Group 2 Innate Lymphoid Cells Are Critical for the Initiation of Adaptive T Helper 2 Cell-mediated Allergic Lung Inflammation
  Immunity. Mar, 2014   |   Pubmed ID: 24613091
• Enu Mutagenesis Identifies a Novel Platelet Phenotype in a Loss-of-function Jak2 Allele
  PloS One. Month, 2013   |   Pubmed ID: 24086539
• SIGIRR, a Negative Regulator of TLR/IL-1R Signalling Promotes Microbiota Dependent Resistance to Colonization by Enteric Bacterial Pathogens
  PLoS Pathogens. Month, 2013   |   Pubmed ID: 23950714
• Requirement for Core 2 O-glycans for Optimal Resistance to Helminth Infection
  PloS One. Month, 2013   |   Pubmed ID: 23555902
• A Familiar Stranger: CD34 Expression and Putative Functions in SVF Cells of Adipose Tissue
  World Journal of Stem Cells. Jan, 2013   |   Pubmed ID: 23362435
• Perinatal Antibiotic Treatment Affects Murine Microbiota, Immune Responses and Allergic Asthma
  Gut Microbes. Mar-Apr, 2013   |   Pubmed ID: 23333861
• IL-7Rα and L-selectin, but Not CD103 or CD34, Are Required for Murine Peanut-induced Anaphylaxis
  Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology. Aug, 2012   |   Pubmed ID: 22935073
• Early Life Antibiotic-driven Changes in Microbiota Enhance Susceptibility to Allergic Asthma
  EMBO Reports. May, 2012   |   Pubmed ID: 22422004
• The Anti-adhesive Mucin Podocalyxin May Help Initiate the Transperitoneal Metastasis of High Grade Serous Ovarian Carcinoma
  Clinical & Experimental Metastasis. Mar, 2012   |   Pubmed ID: 22262060
• Analysis of the Mobilities of Band 3 Populations Associated with Ankyrin Protein and Junctional Complexes in Intact Murine Erythrocytes
  The Journal of Biological Chemistry. Feb, 2012   |   Pubmed ID: 22147703
• Cytopenia Induction by 5-fluorouracil Identifies Thrombopoietic Mutants in Sensitized ENU Mutagenesis Screens
  Experimental Hematology. Jan, 2012   |   Pubmed ID: 21924221
• CD34 Promotes Satellite Cell Motility and Entry into Proliferation to Facilitate Efficient Skeletal Muscle Regeneration
  Stem Cells (Dayton, Ohio). Dec, 2011   |   Pubmed ID: 21997891
• Infiltrating Monocytes Trigger EAE Progression, but Do Not Contribute to the Resident Microglia Pool
  Nature Neuroscience. Sep, 2011   |   Pubmed ID: 21804537
• CD34 is Required for Dendritic Cell Trafficking and Pathology in Murine Hypersensitivity Pneumonitis
  American Journal of Respiratory and Critical Care Medicine. Sep, 2011   |   Pubmed ID: 21642249
• Opposing Roles for CD34 in B16 Melanoma Tumor Growth Alter Early Stage Vasculature and Late Stage Immune Cell Infiltration
  PloS One. Apr, 2011   |   Pubmed ID: 21494591
• A Novel ENU-generated Truncation Mutation Lacking the Spectrin-binding and C-terminal Regulatory Domains of Ank1 Models Severe Hemolytic Hereditary Spherocytosis
  Experimental Hematology. Mar, 2011   |   Pubmed ID: 21193012
• CD34 is Required for Infiltration of Eosinophils into the Colon and Pathology Associated with DSS-induced Ulcerative Colitis
  The American Journal of Pathology. Sep, 2010   |   Pubmed ID: 20696776
• Interleukin-11 Reduces TLR4-induced Colitis in TLR2-deficient Mice and Restores Intestinal STAT3 Signaling
  Gastroenterology. Oct, 2010   |   Pubmed ID: 20600022
• CD34 Mediates Intestinal Inflammation in Salmonella-infected Mice
  Cellular Microbiology. Nov, 2010   |   Pubmed ID: 20497179
• The Metalloprotease-disintegrin ADAM8 is Essential for the Development of Experimental Asthma
  American Journal of Respiratory and Critical Care Medicine. Jun, 2010   |   Pubmed ID: 20194813
• Loss of CD34 Leads to Exacerbated Autoimmune Arthritis Through Increased Vascular Permeability
  Journal of Immunology (Baltimore, Md. : 1950). Feb, 2010   |   Pubmed ID: 20038636
• Stem Cells, Inflammation and Allergy
  Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology. Dec, 2009   |   Pubmed ID: 20066174
• Prion Protein Expression and Release by Mast Cells After Activation
  The Journal of Infectious Diseases. Sep, 2009   |   Pubmed ID: 19642931
• SHIP1 is a Repressor of Mast Cell Hyperplasia, Cytokine Production, and Allergic Inflammation in Vivo
  Journal of Immunology (Baltimore, Md. : 1950). Jul, 2009   |   Pubmed ID: 19542434
• Bone Marrow-derived Mast Cells Accumulate in the Central Nervous System During Inflammation but Are Dispensable for Experimental Autoimmune Encephalomyelitis Pathogenesis
  Journal of Immunology (Baltimore, Md. : 1950). May, 2009   |   Pubmed ID: 19380799
• Mast Cells in Tumor Growth: Angiogenesis, Tissue Remodelling and Immune-modulation
  Biochimica Et Biophysica Acta. Aug, 2009   |   Pubmed ID: 19233249
• Podocalyxin Selectively Marks Erythroid-committed Progenitors During Anemic Stress but is Dispensable for Efficient Recovery
  Experimental Hematology. Jan, 2009   |   Pubmed ID: 19004540
• Mast Cells Are an Essential Hematopoietic Component for Polyp Development
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2007   |   Pubmed ID: 18077429
• CD34 Facilitates the Development of Allergic Asthma
  Blood. Sep, 2007   |   Pubmed ID: 17557898
• The CD34-related Molecule Podocalyxin is a Potent Inducer of Microvillus Formation
  PloS One. Feb, 2007   |   Pubmed ID: 17311105
• Na+/H+ Exchanger Regulatory Factor-1 is a Hematopoietic Ligand for a Subset of the CD34 Family of Stem Cell Surface Proteins
  Stem Cells (Dayton, Ohio). May, 2006   |   Pubmed ID: 16410385
• Hematopoietic Stem Cells Do Not Engraft with Absolute Efficiencies
  Blood. Jan, 2006   |   Pubmed ID: 16204316
• Podocalyxin is a CD34-related Marker of Murine Hematopoietic Stem Cells and Embryonic Erythroid Cells
  Blood. Jun, 2005   |   Pubmed ID: 15701716
• CD34 and CD43 Inhibit Mast Cell Adhesion and Are Required for Optimal Mast Cell Reconstitution
  Immunity. Jan, 2005   |   Pubmed ID: 15664158
• Overexpression of the Anti-adhesin Podocalyxin is an Independent Predictor of Breast Cancer Progression
  Cancer Research. Aug, 2004   |   Pubmed ID: 15289306
• E26 Leukemia Virus Converts Primitive Erythroid Cells into Cycling Multilineage Progenitors
  Blood. Feb, 2003   |   Pubmed ID: 12393697
• CD34 is a Specific Marker of Mature Murine Mast Cells
  Experimental Hematology. Oct, 2002   |   Pubmed ID: 12384153
• Avian Models to Study the Transcriptional Control of Hematopoietic Lineage Commitment and to Identify Lineage-specific Genes
  Cells, Tissues, Organs. Month, 2002   |   Pubmed ID: 12021491
• Anuria, Omphalocele, and Perinatal Lethality in Mice Lacking the CD34-related Protein Podocalyxin
  The Journal of Experimental Medicine. Jul, 2001   |   Pubmed ID: 11435469