Kenju Shimomura

Publications

• The Deletion of Glucagon-like Peptide-1 Receptors Expressing Neurons in the Dorsomedial Hypothalamic Nucleus Disrupts the Diurnal Feeding Pattern and Induces Hyperphagia and Obesity
  Nutrition & Metabolism. Jun, 2021  |   Pubmed ID: 34098999
• Evaluation of Effect of Ninjin'yoeito on Regional Brain Glucose Metabolism by F-FDG Autoradiography With Insulin Loading in Aged Mice
  Frontiers in Nutrition. 2021  |   Pubmed ID: 34055854
• Construction of Patient-derived Tumor Models to Evaluate Anticancer Agents and Cancer Immunotherapy
  Oncology Letters. May, 2021  |   Pubmed ID: 33841567
• Evaluation of Organ Glucose Metabolism by F-FDG Accumulation with Insulin Loading in Aged Mice Compared with Young Normal Mice
  Scientific Reports. Apr, 2021  |   Pubmed ID: 33795778
• Structure Based Analysis of K Channel with a DEND Syndrome Mutation in Murine Skeletal Muscle
  Scientific Reports. Mar, 2021  |   Pubmed ID: 33758250
• Urinary Excretion of Nadolol As a Possible In Vivo Probe for Drug Interactions Involving P-Glycoprotein
  Journal of Clinical Pharmacology. Jun, 2021  |   Pubmed ID: 33387374
• Opening of Intermediate Conductance Ca-Activated K Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter Via the Akt/Mammalian Target of Rapamycin Pathway
  The Journal of Pharmacology and Experimental Therapeutics. 03, 2021  |   Pubmed ID: 33376149
• Impact of Green Tea Catechin Ingestion on the Pharmacokinetics of Lisinopril in Healthy Volunteers
  Clinical and Translational Science. Mar, 2021  |   Pubmed ID: 33048477
• Targeting Oxytocin Receptor (Oxtr)-expressing Neurons in the Lateral Septum to Restore Social Novelty in Autism Spectrum Disorder Mouse Models
  Scientific Reports. 12, 2020  |   Pubmed ID: 33335150
• Detection of NUCB2/nesfatin-1 in Cerebrospinal Fluid of Multiple Sclerosis Patients
  Aging. 12, 2020  |   Pubmed ID: 33318307
• Gs/Gq Signaling Switch in β Cells Defines Incretin Effectiveness in Diabetes
  The Journal of Clinical Investigation. 12, 2020  |   Pubmed ID: 33196462
• Single Administration of Resveratrol Improves Social Behavior in Adult Mouse Models of Autism Spectrum Disorder
  Bioscience, Biotechnology, and Biochemistry. Nov, 2020  |   Pubmed ID: 32698690
• Early Life High-fat Diet Exposure Evokes Normal Weight Obesity
  Nutrition & Metabolism. 2020  |   Pubmed ID: 32595758
• Goshajinkigan, a Traditional Japanese Medicine, Suppresses Voltage-Gated Sodium Channel Nav1.4 Currents in C2C12 Cells
  BioResearch Open Access. 2020  |   Pubmed ID: 32368413
• Effects of Single Green Tea Ingestion on Pharmacokinetics of Nadolol in Healthy Volunteers
  British Journal of Clinical Pharmacology. 11, 2020  |   Pubmed ID: 32320490
• Oral Oxytocin Delivery with Proton Pump Inhibitor Pretreatment Decreases Food Intake
  Peptides. 06, 2020  |   Pubmed ID: 32298773
• Atorvastatin-Green Tea Interaction: Possible Mechanisms Are Complicated, But Clinical Relevance is Not?
  European Journal of Drug Metabolism and Pharmacokinetics. 06, 2020  |   Pubmed ID: 32297048
• TAK-242, a Specific Inhibitor of Toll-like Receptor 4 Signalling, Prevents Endotoxemia-induced Skeletal Muscle Wasting in Mice
  Scientific Reports. 01, 2020  |   Pubmed ID: 31959927
• Cluster of Differentiation 8 and Programmed Cell Death Ligand 1 Expression in Triple-negative Breast Cancer Combined with Autosomal Dominant Polycystic Kidney Disease and Tuberous Sclerosis Complex: a Case Report
  Journal of Medical Case Reports. Dec, 2019  |   Pubmed ID: 31870441
• The Hypothalamus to Brainstem Circuit Suppresses Late-onset Body Weight Gain
  Scientific Reports. 12, 2019  |   Pubmed ID: 31798010
• Association Between Cognitive Impairment Patient with Solid Cancer and Insulin Resistance
  BMC Research Notes. Oct, 2019  |   Pubmed ID: 31661025
• The SGLT2 Inhibitor Canagliflozin Prevents Carcinogenesis in a Mouse Model of Diabetes and Non-Alcoholic Steatohepatitis-Related Hepatocarcinogenesis: Association with SGLT2 Expression in Hepatocellular Carcinoma
  International Journal of Molecular Sciences. Oct, 2019  |   Pubmed ID: 31652578
• The Undeveloped Properties of GABA Neurons in the Ventral Tegmental Area Promote Energy Intake for Growth in Juvenile Rats
  Scientific Reports. 08, 2019  |   Pubmed ID: 31413349
• An In Vitro System for Evaluating Molecular Targeted Drugs Using Lung Patient-Derived Tumor Organoids
  Cells. 05, 2019  |   Pubmed ID: 31137590
• MLH1 Germline Mutation Associated with Lynch Syndrome in a Family Followed for More Than 45 years
  BMC Medical Genetics. 05, 2019  |   Pubmed ID: 31046708
• Noninvasive Continuous Blood Pressure Monitoring Using Microelectromechanical System Technology
  Blood Pressure Monitoring. Jun, 2019  |   Pubmed ID: 30998555
• LGR4 is Essential for R-spondin1-mediated Suppression of Food Intake Via Pro-opiomelanocortin
  Bioscience, Biotechnology, and Biochemistry. Jul, 2019  |   Pubmed ID: 30916623
• Impact of Dapagliflozin, an SGLT2 Inhibitor, on Serum Levels of Soluble Dipeptidyl Peptidase-4 in Patients with Type 2 Diabetes and Non-alcoholic Fatty Liver Disease
  International Journal of Clinical Practice. May, 2019  |   Pubmed ID: 30810254
• Structural Basis of Different Substrate Preferences of Two Old Yellow Enzymes from Yeasts in the Asymmetric Reduction of Enone Compounds
  Bioscience, Biotechnology, and Biochemistry. Mar, 2019  |   Pubmed ID: 30445889
• Excitability of Oxytocin Neurons in Paraventricular Nucleus is Regulated by Voltage-gated Potassium Channels Kv4.2 and Kv4.3
  Bioscience, Biotechnology, and Biochemistry. Feb, 2019  |   Pubmed ID: 30392457
• The Effect of Avertin Anesthesia and a Mixture of Three Types of Anesthetic Agents on Food Intakeand Body Weight in High Fat-induced Obese Maleand Female Mice
  Experimental Animals. Feb, 2019  |   Pubmed ID: 30210091
• Poland Syndrome Accompanied by Internal Iliac Artery Supply Disruption Sequence: a Case Report
  Journal of Medical Case Reports. Oct, 2018  |   Pubmed ID: 30360754
• Memantine Has No Effect on K Channels in Pancreatic β Cells
  BMC Research Notes. Aug, 2018  |   Pubmed ID: 30144824
• Similar Effect of Quercetin on CYP2E1 and CYP2C9 Activities in Humans?
  European Journal of Clinical Pharmacology. Sep, 2018  |   Pubmed ID: 29770840
• Update of Green Tea Interactions with Cardiovascular Drugs and putative Mechanisms
  Journal of Food and Drug Analysis. 04, 2018  |   Pubmed ID: 29703388
• The Anorexigenic Neural Pathways of Oxytocin and Their Clinical Implication
  Neuroendocrinology. 2018  |   Pubmed ID: 29660735
• Action Selection and Flexible Switching Controlled by the Intralaminar Thalamic Neurons
  Cell Reports. 02, 2018  |   Pubmed ID: 29490273
• K Channel Mutations and Neonatal Diabetes
  Internal Medicine (Tokyo, Japan). Sep, 2017  |   Pubmed ID: 28824061
• Impact of Sex, Fat Distribution and Initial Body Weight on Oxytocin's Body Weight Regulation
  Scientific Reports. 08, 2017  |   Pubmed ID: 28819236
• Nesfatin-1 Inhibits Voltage Gated K Channels in Pancreatic Beta Cells
  Peptides. Sep, 2017  |   Pubmed ID: 28697955
• Non-alcoholic Fatty Liver Disease Is a Risk Factor for Type 2 Diabetes in Middle-aged Japanese Men and Women
  Internal Medicine (Tokyo, Japan). 2017  |   Pubmed ID: 28381741
• Orexin Action on Oxytocin Neurons in the Paraventricular Nucleus of the Hypothalamus
  Neuroreport. Apr, 2017  |   Pubmed ID: 28338525
• Islet Insulin Secretion Measurements in the Mouse
  Current Protocols in Mouse Biology. Sep, 2016  |   Pubmed ID: 27584553
• Projections from a Single NUCB2/nesfatin-1 Neuron in the Paraventricular Nucleus to Different Brain Regions Involved in Feeding
  Brain Structure & Function. 12, 2016  |   Pubmed ID: 26639940
• Central Action of ELABELA Reduces Food Intake and Activates Arginine Vasopressin and Corticotropin-releasing Hormone Neurons in the Hypothalamic Paraventricular Nucleus
  Neuroreport. Sep, 2015  |   Pubmed ID: 26237243
• Water Intake Disorder in a DEND Syndrome Afflicted Patient with R50P Mutation
  Endocrine Journal. 2015  |   Pubmed ID: 25739471
• Oxytocinergic Circuit from Paraventricular and Supraoptic Nuclei to Arcuate POMC Neurons in Hypothalamus
  FEBS Letters. Nov, 2014  |   Pubmed ID: 25448678
• Chronic Phencyclidine Treatment Induces Long-lasting Glutamatergic Activation of VTA Dopamine Neurons
  Neuroscience Letters. Apr, 2014  |   Pubmed ID: 24525246