Kenneth J. Pienta

Publications

• The Role of Heterogeneous Environment and Docetaxel Gradient in the Emergence of Polyploid, Mesenchymal and Resistant Prostate Cancer Cells
  Clinical & Experimental Metastasis. Apr, 2019  |   Pubmed ID: 30810874
• Cancer As a Social Dysfunction-Why Cancer Research Needs New Thinking
  Molecular Cancer Research : MCR. 09, 2018  |   Pubmed ID: 29784670
• Epithelial and Mesenchymal Prostate Cancer Cell Population Dynamics on a Complex Drug Landscape
  Convergent Science Physical Oncology. Dec, 2017  |   Pubmed ID: 29527324
• Re: Stromal Gene Expression is Predictive for Metastatic Primary Prostate Cancer
  European Urology. Dec, 2017  |   Pubmed ID: 29221660
• Positive Feedback Loops Between Inflammatory, Bone and Cancer Cells During Metastatic Niche Construction
  Advances in Experimental Medicine and Biology. 2016  |   Pubmed ID: 27739046
• Stability of the Hybrid Epithelial/mesenchymal Phenotype
  Oncotarget. Mar, 2016  |   Pubmed ID: 27008704
• Disseminated Tumor Cells and Dormancy in Prostate Cancer Metastasis
  Current Opinion in Biotechnology. Feb, 2016  |   Pubmed ID: 26900985
• Polyclonal Breast Cancer Metastases Arise from Collective Dissemination of Keratin 14-expressing Tumor Cell Clusters
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016  |   Pubmed ID: 26831077
• Development of an Automated and Sensitive Microfluidic Device for Capturing and Characterizing Circulating Tumor Cells (CTCs) from Clinical Blood Samples
  PloS One. 2016  |   Pubmed ID: 26808060
• PSMA-Based Detection of Prostate Cancer Bone Lesions With (18)F-DCFPyL PET/CT: A Sensitive Alternative to (99m)Tc-MDP Bone Scan and Na(18)F PET/CT?
  Clinical Genitourinary Cancer. Feb, 2016  |   Pubmed ID: 26603549
• Multidisciplinary Intervention of Early, Lethal Metastatic Prostate Cancer: Report from the 2015 Coffey-Holden Prostate Cancer Academy Meeting
  The Prostate. Feb, 2016  |   Pubmed ID: 26477609
• Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide
  PloS One. 2015  |   Pubmed ID: 26571387
• Bone Marrow Macrophages Support Prostate Cancer Growth in Bone
  Oncotarget. Nov, 2015  |   Pubmed ID: 26459393
• Ecological Paradigms to Understand the Dynamics of Metastasis
  Cancer Letters. Oct, 2015  |   Pubmed ID: 26458994
• Coupling the Modules of EMT and Stemness: A Tunable 'stemness Window' Model
  Oncotarget. Sep, 2015  |   Pubmed ID: 26317796
• A Phase 3 Trial of 2 Years of Androgen Suppression and Radiation Therapy With or Without Adjuvant Chemotherapy for High-Risk Prostate Cancer: Final Results of Radiation Therapy Oncology Group Phase 3 Randomized Trial NRG Oncology RTOG 9902
  International Journal of Radiation Oncology, Biology, Physics. Oct, 2015  |   Pubmed ID: 26209502
• Oligometastatic Prostate Cancer to the Navicular Bone: Case Report
  Urology Case Reports. May, 2015  |   Pubmed ID: 26029631
• Drug Discovery in Prostate Cancer Mouse Models
  Expert Opinion on Drug Discovery. 2015  |   Pubmed ID: 26027638
• Integrative Clinical Genomics of Advanced Prostate Cancer
  Cell. May, 2015  |   Pubmed ID: 26000489
• OVOL Guides the Epithelial-hybrid-mesenchymal Transition
  Oncotarget. Jun, 2015  |   Pubmed ID: 25944618
• The Biology and Treatment of Oligometastatic Cancer
  Oncotarget. Apr, 2015  |   Pubmed ID: 25940699
• Ecology Meets Cancer Biology: the Cancer Swamp Promotes the Lethal Cancer Phenotype
  Oncotarget. Apr, 2015  |   Pubmed ID: 25895024
• Therapy Decisions for the Symptomatic Patient with Metastatic Castration-resistant Prostate Cancer
  Asian Journal of Andrology. Nov-Dec, 2015  |   Pubmed ID: 25865849
• Integrated Multimodal Imaging of Dynamic Bone-tumor Alterations Associated with Metastatic Prostate Cancer
  PloS One. 2015  |   Pubmed ID: 25859981
• Alternative CD44 Splicing Identifies Epithelial Prostate Cancer Cells from the Mesenchymal Counterparts
  Medical Oncology (Northwood, London, England). May, 2015  |   Pubmed ID: 25850653
• Aerobic Glycolysis, Motility, and Cytoskeletal Remodeling
  Cell Cycle (Georgetown, Tex.). 2015  |   Pubmed ID: 25530323
• Magnetic Resonance-invisible Versus Magnetic Resonance-visible Prostate Cancer in Active Surveillance: a Preliminary Report on Disease Outcomes
  Urology. Jan, 2015  |   Pubmed ID: 25440986
• Glycolysis is the Primary Bioenergetic Pathway for Cell Motility and Cytoskeletal Remodeling in Human Prostate and Breast Cancer Cells
  Oncotarget. Jan, 2015  |   Pubmed ID: 25426557
• Beyond Immune Checkpoint Blockade: New Approaches to Targeting Host-tumor Interactions in Prostate Cancer: Report from the 2014 Coffey-Holden Prostate Cancer Academy Meeting
  The Prostate. Mar, 2015  |   Pubmed ID: 25358693
• Epithelial-mesenchymal Transition in Prostate Cancer is Associated with Quantifiable Changes in Nuclear Structure
  The Prostate. Feb, 2015  |   Pubmed ID: 25327565
• The Presence of Androgen Receptor Elements Regulates ZEB1 Expression in the Absence of Androgen Receptor
  Journal of Cellular Biochemistry. Jan, 2015  |   Pubmed ID: 25160502
• TAM Macrophages Promote Growth and Metastasis Within the Cancer Ecosystem
  Oncoimmunology. 2014  |   Pubmed ID: 25954596
• Classification of Current Anticancer Immunotherapies
  Oncotarget. Dec, 2014  |   Pubmed ID: 25537519
• Axl As a Mediator of Cellular Growth and Survival
  Oncotarget. Oct, 2014  |   Pubmed ID: 25344858
• Critical Transitions in a Game Theoretic Model of Tumour Metabolism
  Interface Focus. Aug, 2014  |   Pubmed ID: 25097747
• Genetic Ablation of Metadherin Inhibits Autochthonous Prostate Cancer Progression and Metastasis
  Cancer Research. Sep, 2014  |   Pubmed ID: 25074613
• Frequent Discordance Between ERG Gene Rearrangement and ERG Protein Expression in a Rapid Autopsy Cohort of Patients with Lethal, Metastatic, Castration-resistant Prostate Cancer
  The Prostate. Sep, 2014  |   Pubmed ID: 25043157
• Polarization of Prostate Cancer-associated Macrophages is Induced by Milk Fat Globule-EGF Factor 8 (MFG-E8)-mediated Efferocytosis
  The Journal of Biological Chemistry. Aug, 2014  |   Pubmed ID: 25006249
• Cross-species Regulatory Network Analysis Identifies a Synergistic Interaction Between FOXM1 and CENPF That Drives Prostate Cancer Malignancy
  Cancer Cell. May, 2014  |   Pubmed ID: 24823640
• Niche Inheritance: a Cooperative Pathway to Enhance Cancer Cell Fitness Through Ecosystem Engineering
  Journal of Cellular Biochemistry. Sep, 2014  |   Pubmed ID: 24700698
• Endothelial Integrin α3β1 Stabilizes Carbohydrate-mediated Tumor/endothelial Cell Adhesion and Induces Macromolecular Signaling Complex Formation at the Endothelial Cell Membrane
  Oncotarget. Mar, 2014  |   Pubmed ID: 24675526
• Dynamic Regulation of Rad51 by E2F1 and P53 in Prostate Cancer Cells Upon Drug-induced DNA Damage Under Hypoxia
  Molecular Pharmacology. Jun, 2014  |   Pubmed ID: 24627085
• A Bioinformatics Approach Reveals Novel Interactions of the OVOL Transcription Factors in the Regulation of Epithelial - Mesenchymal Cell Reprogramming and Cancer Progression
  BMC Systems Biology. 2014  |   Pubmed ID: 24612742
• A Multi-targeted Approach to Treating Bone Metastases
  Cancer Metastasis Reviews. Sep, 2014  |   Pubmed ID: 24390423
• Beyond the Androgen Receptor: New Approaches to Treating Metastatic Prostate Cancer. Report of the 2013 Prouts Neck Prostate Cancer Meeting
  The Prostate. Feb, 2014  |   Pubmed ID: 24249419
• Prostate Cancer Originating in Basal Cells Progresses to Adenocarcinoma Propagated by Luminal-like Cells
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2013  |   Pubmed ID: 24282295
• Metastatic Castration-resistant Prostate Cancer Reveals Intrapatient Similarity and Interpatient Heterogeneity of Therapeutic Kinase Targets
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2013  |   Pubmed ID: 24248375
• Activating ESR1 Mutations in Hormone-resistant Metastatic Breast Cancer
  Nature Genetics. Dec, 2013  |   Pubmed ID: 24185510
• Transcription Factors OVOL1 and OVOL2 Induce the Mesenchymal to Epithelial Transition in Human Cancer
  PloS One. 2013  |   Pubmed ID: 24124593
• The Cancer Diaspora: Metastasis Beyond the Seed and Soil Hypothesis
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2013  |   Pubmed ID: 24100626
• The Long Noncoding RNA SChLAP1 Promotes Aggressive Prostate Cancer and Antagonizes the SWI/SNF Complex
  Nature Genetics. Nov, 2013  |   Pubmed ID: 24076601
• TBK1 Regulates Prostate Cancer Dormancy Through MTOR Inhibition
  Neoplasia (New York, N.Y.). Sep, 2013  |   Pubmed ID: 24027431
• Circulating MicroRNA Profiling Identifies a Subset of Metastatic Prostate Cancer Patients with Evidence of Cancer-associated Hypoxia
  PloS One. 2013  |   Pubmed ID: 23935962
• Words of Wisdom: Re: Androgen Receptor Splice Variants Mediate Enzalutamide Resistance in Castration-resistant Prostate Cancer Cell Lines
  European Urology. Aug, 2013  |   Pubmed ID: 23830228
• Erythropoietin Supports the Survival of Prostate Cancer, but Not Growth and Bone Metastasis
  Journal of Cellular Biochemistry. Nov, 2013  |   Pubmed ID: 23696192
• Recruitment of Mesenchymal Stem Cells into Prostate Tumours Promotes Metastasis
  Nature Communications. 2013  |   Pubmed ID: 23653207
• GAS6 Receptor Status is Associated with Dormancy and Bone Metastatic Tumor Formation
  PloS One. 2013  |   Pubmed ID: 23637920
• Identification of Targetable FGFR Gene Fusions in Diverse Cancers
  Cancer Discovery. Jun, 2013  |   Pubmed ID: 23558953
• The 19th Annual Prostate Cancer Foundation Scientific Retreat
  Cancer Research. Aug, 2013  |   Pubmed ID: 23536559
• Cancer Stem Cells and Their Role in Metastasis
  Pharmacology & Therapeutics. May, 2013  |   Pubmed ID: 23384596
• Identification of Recurrent NAB2-STAT6 Gene Fusions in Solitary Fibrous Tumor by Integrative Sequencing
  Nature Genetics. Feb, 2013  |   Pubmed ID: 23313952
• Definition of Molecular Determinants of Prostate Cancer Cell Bone Extravasation
  Cancer Research. Jan, 2013  |   Pubmed ID: 23149920
• Phase 2 Study of Carlumab (CNTO 888), a Human Monoclonal Antibody Against CC-chemokine Ligand 2 (CCL2), in Metastatic Castration-resistant Prostate Cancer
  Investigational New Drugs. Jun, 2013  |   Pubmed ID: 22907596
• Circulating Fibroblast-like Cells in Men with Metastatic Prostate Cancer
  The Prostate. Jan, 2013  |   Pubmed ID: 22718300
• Role of Transcriptional Corepressor CtBP1 in Prostate Cancer Progression
  Neoplasia (New York, N.Y.). Oct, 2012  |   Pubmed ID: 23097625
• Prevalence of Prostate Cancer Metastases After Intravenous Inoculation Provides Clues into the Molecular Basis of Dormancy in the Bone Marrow Microenvironment
  Neoplasia (New York, N.Y.). May, 2012  |   Pubmed ID: 22745589
• The Mutational Landscape of Lethal Castration-resistant Prostate Cancer
  Nature. Jul, 2012  |   Pubmed ID: 22722839
• Cyclophosphamide Creates a Receptive Microenvironment for Prostate Cancer Skeletal Metastasis
  Cancer Research. May, 2012  |   Pubmed ID: 22589273
• Systemic Delivery of Oncolytic Adenoviruses Targeting Transforming Growth Factor-β Inhibits Established Bone Metastasis in a Prostate Cancer Mouse Model
  Human Gene Therapy. Aug, 2012  |   Pubmed ID: 22551458
• Hypoxia Stabilizes GAS6/Axl Signaling in Metastatic Prostate Cancer
  Molecular Cancer Research : MCR. Jun, 2012  |   Pubmed ID: 22516347
• Forging the Association for Clinical and Translational Science (ACTS)
  Clinical and Translational Science. Apr, 2012  |   Pubmed ID: 22507114
• Disrupting the Networks of Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2012  |   Pubmed ID: 22442061
• Role of Dutasteride in Pre-clinical ETS Fusion-positive Prostate Cancer Models
  The Prostate. Mar, 2012  |   Pubmed ID: 22415461
• The Prostate Cancer Bone Marrow Niche: More Than Just 'fertile Soil'
  Asian Journal of Andrology. May, 2012  |   Pubmed ID: 22367179
• Inhibition of Prostate Cancer Bone Metastasis by Synthetic TF Antigen Mimic/galectin-3 Inhibitor Lactulose-L-leucine
  Neoplasia (New York, N.Y.). Jan, 2012  |   Pubmed ID: 22355275
• Disseminated Prostate Cancer Cells Can Instruct Hematopoietic Stem and Progenitor Cells to Regulate Bone Phenotype
  Molecular Cancer Research : MCR. Mar, 2012  |   Pubmed ID: 22241219
• Chemical Transfection of Dye-conjugated MicroRNA Precursors for MicroRNA Functional Analysis of M2 Macrophages
  Journal of Cellular Biochemistry. May, 2012  |   Pubmed ID: 22213010
• IL-4 Induces Proliferation in Prostate Cancer PC3 Cells Under Nutrient-depletion Stress Through the Activation of the JNK-pathway and Survivin Up-regulation
  Journal of Cellular Biochemistry. May, 2012  |   Pubmed ID: 22174091
• 384 Hanging Drop Arrays Give Excellent Z-factors and Allow Versatile Formation of Co-culture Spheroids
  Biotechnology and Bioengineering. May, 2012  |   Pubmed ID: 22161651
• Common Structural and Epigenetic Changes in the Genome of Castration-resistant Prostate Cancer
  Cancer Research. Feb, 2012  |   Pubmed ID: 22158653
• Micro-ring Structures Stabilize Microdroplets to Enable Long Term Spheroid Culture in 384 Hanging Drop Array Plates
  Biomedical Microdevices. Apr, 2012  |   Pubmed ID: 22057945
• Molecular Characterization of Neuroendocrine Prostate Cancer and Identification of New Drug Targets
  Cancer Discovery. Nov, 2011  |   Pubmed ID: 22389870
• Nanoparticle Induced Cell Magneto-rotation: Monitoring Morphology, Stress and Drug Sensitivity of a Suspended Single Cancer Cell
  PloS One. 2011  |   Pubmed ID: 22180784
• Personalized Oncology Through Integrative High-throughput Sequencing: a Pilot Study
  Science Translational Medicine. Nov, 2011  |   Pubmed ID: 22133722
• Detection of Somatic Copy Number Alterations in Cancer Using Targeted Exome Capture Sequencing
  Neoplasia (New York, N.Y.). Nov, 2011  |   Pubmed ID: 22131877
• Mechanisms of Cancer Cell Metastasis to the Bone: a Multistep Process
  Future Oncology (London, England). Nov, 2011  |   Pubmed ID: 22044203
• Centralized Research Recruitment-evolving a Local Clinical Research Recruitment Web Application to Better Meet User Needs
  Clinical and Translational Science. Oct, 2011  |   Pubmed ID: 22029810
• The Importance of Proposed Changes in the "Common Rule" for -clinical and Translational Researchers
  Clinical and Translational Science. Oct, 2011  |   Pubmed ID: 22029799
• Modeling Invasion of Metastasizing Cancer Cells to Bone Marrow Utilizing Ecological Principles
  Theoretical Biology & Medical Modelling. 2011  |   Pubmed ID: 21967667
• The Clinical and Translational Science Awards (CTSAs) Are Transforming the Way Academic Medical Institutions Approach Translational Research: the University of Michigan Experience
  Clinical and Translational Science. Aug, 2011  |   Pubmed ID: 21884508
• Homing of Cancer Cells to the Bone
  Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society. Dec, 2011  |   Pubmed ID: 21826451
• Hematopoietic Stem Cell Niche is a Potential Therapeutic Target for Bone Metastatic Tumors
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2011  |   Pubmed ID: 21676926
• Mechanistic Rationale for Inhibition of Poly(ADP-ribose) Polymerase in ETS Gene Fusion-positive Prostate Cancer
  Cancer Cell. May, 2011  |   Pubmed ID: 21575865
• Characterization of Bone Metastases from Rapid Autopsies of Prostate Cancer Patients
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2011  |   Pubmed ID: 21555375
• Human Prostate Cancer Metastases Target the Hematopoietic Stem Cell Niche to Establish Footholds in Mouse Bone Marrow
  The Journal of Clinical Investigation. Apr, 2011  |   Pubmed ID: 21436587
• Drugs Which Inhibit Osteoclast Function Suppress Tumor Growth Through Calcium Reduction in Bone
  Bone. Jun, 2011  |   Pubmed ID: 21419883
• Therapeutic Targeting of SPINK1-positive Prostate Cancer
  Science Translational Medicine. Mar, 2011  |   Pubmed ID: 21368222
• Activation of Urokinase Plasminogen Activator and Its Receptor Axis is Essential for Macrophage Infiltration in a Prostate Cancer Mouse Model
  Neoplasia (New York, N.Y.). Jan, 2011  |   Pubmed ID: 21245937
• Copy Number and Targeted Mutational Analysis Reveals Novel Somatic Events in Metastatic Prostate Tumors
  Genome Research. Jan, 2011  |   Pubmed ID: 21147910
• Inherited Variants in the Chemokine CCL2 Gene and Prostate Cancer Aggressiveness in a Caucasian Cohort
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2011  |   Pubmed ID: 21135144
• Inhibitory Effects of Megakaryocytic Cells in Prostate Cancer Skeletal Metastasis
  Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jan, 2011  |   Pubmed ID: 20684002
• Cilengitide (EMD 121974, NSC 707544) in Asymptomatic Metastatic Castration Resistant Prostate Cancer Patients: a Randomized Phase II Trial by the Prostate Cancer Clinical Trials Consortium
  Investigational New Drugs. Dec, 2011  |   Pubmed ID: 20336348
• Successfully Accelerating Translational Research at an Academic Medical Center: the University of Michigan-Coulter Translational Research Partnership Program
  Clinical and Translational Science. Dec, 2010  |   Pubmed ID: 21167009
• Targeting Chemokine (C-C Motif) Ligand 2 (CCL2) As an Example of Translation of Cancer Molecular Biology to the Clinic
  Progress in Molecular Biology and Translational Science. 2010  |   Pubmed ID: 21075328
• CXCL12 / CXCR4 / CXCR7 Chemokine Axis and Cancer Progression
  Cancer Metastasis Reviews. Dec, 2010  |   Pubmed ID: 20839032
• AT-101 (R-(-)-gossypol Acetic Acid) Enhances the Effectiveness of Androgen Deprivation Therapy in the VCaP Prostate Cancer Model
  Journal of Cellular Biochemistry. Aug, 2010  |   Pubmed ID: 20589722
• Erythropoietin Couples Hematopoiesis with Bone Formation
  PloS One. 2010  |   Pubmed ID: 20523730
• Single Cell Trapping in Larger Microwells Capable of Supporting Cell Spreading and Proliferation
  Microfluidics and Nanofluidics. Feb, 2010  |   Pubmed ID: 20352022
• The CTSA Mandate: Are We There Yet?
  Research and Theory for Nursing Practice. 2010  |   Pubmed ID: 20333913
• Multiple Roles of Chemokine (C-C Motif) Ligand 2 in Promoting Prostate Cancer Growth
  Journal of the National Cancer Institute. Apr, 2010  |   Pubmed ID: 20233997
• GAS6/AXL Axis Regulates Prostate Cancer Invasion, Proliferation, and Survival in the Bone Marrow Niche
  Neoplasia (New York, N.Y.). Feb, 2010  |   Pubmed ID: 20126470
• Characterization of Phosphoglycerate Kinase-1 Expression of Stromal Cells Derived from Tumor Microenvironment in Prostate Cancer Progression
  Cancer Research. Jan, 2010  |   Pubmed ID: 20068185
• CC Chemokine Ligand 2 (CCL2) Promotes Prostate Cancer Tumorigenesis and Metastasis
  Cytokine & Growth Factor Reviews. Feb, 2010  |   Pubmed ID: 20005149
• CCL2 is a Negative Regulator of AMP-activated Protein Kinase to Sustain MTOR Complex-1 Activation, Survivin Expression, and Cell Survival in Human Prostate Cancer PC3 Cells
  Neoplasia (New York, N.Y.). Dec, 2009  |   Pubmed ID: 20019839
• Alpha 1,3 Fucosyltransferases Are Master Regulators of Prostate Cancer Cell Trafficking
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2009  |   Pubmed ID: 19889975
• The Chemokine CCL2 Increases Prostate Tumor Growth and Bone Metastasis Through Macrophage and Osteoclast Recruitment
  Neoplasia (New York, N.Y.). Nov, 2009  |   Pubmed ID: 19881959
• CCL2 and Interleukin-6 Promote Survival of Human CD11b+ Peripheral Blood Mononuclear Cells and Induce M2-type Macrophage Polarization
  The Journal of Biological Chemistry. Dec, 2009  |   Pubmed ID: 19833726
• Possible Mechanism of CCL2-induced Akt Activation in Prostate Cancer Cells
  Anticancer Research. Aug, 2009  |   Pubmed ID: 19661323
• Critical Appraisal of Prostate-specific Antigen in Prostate Cancer Screening: 20 Years Later
  Urology. May, 2009  |   Pubmed ID: 19375622
• Treatment-dependent Androgen Receptor Mutations in Prostate Cancer Exploit Multiple Mechanisms to Evade Therapy
  Cancer Research. May, 2009  |   Pubmed ID: 19366804
• Microfluidic System for Formation of PC-3 Prostate Cancer Co-culture Spheroids
  Biomaterials. Jun, 2009  |   Pubmed ID: 19304321
• Regulation of Prostate Cancer Progression by Galectin-3
  The American Journal of Pathology. Apr, 2009  |   Pubmed ID: 19286570
• Synergy Between Anti-CCL2 and Docetaxel As Determined by DW-MRI in a Metastatic Bone Cancer Model
  Journal of Cellular Biochemistry. May, 2009  |   Pubmed ID: 19259948
• Circulating Tumour Cells As Prognostic Markers in Progressive, Castration-resistant Prostate Cancer: a Reanalysis of IMMC38 Trial Data
  The Lancet. Oncology. Mar, 2009  |   Pubmed ID: 19213602
• A Destructive Cascade Mediated by CCL2 Facilitates Prostate Cancer Growth in Bone
  Cancer Research. Feb, 2009  |   Pubmed ID: 19176388
• Prostate Cancer Promotes CD11b Positive Cells to Differentiate into Osteoclasts
  Journal of Cellular Biochemistry. Mar, 2009  |   Pubmed ID: 19170075
• Phase III Multi-institutional Trial of Adjuvant Chemotherapy with Paclitaxel, Estramustine, and Oral Etoposide Combined with Long-term Androgen Suppression Therapy and Radiotherapy Versus Long-term Androgen Suppression Plus Radiotherapy Alone for High-risk Prostate Cancer: Preliminary Toxicity Analysis of RTOG 99-02
  International Journal of Radiation Oncology, Biology, Physics. Mar, 2009  |   Pubmed ID: 18990504
• FYN is Overexpressed in Human Prostate Cancer
  BJU International. Jan, 2009  |   Pubmed ID: 18990162
• Ecological Therapy for Cancer: Defining Tumors Using an Ecosystem Paradigm Suggests New Opportunities for Novel Cancer Treatments
  Translational Oncology. Dec, 2008  |   Pubmed ID: 19043526
• -(-)Gossypol Promotes the Apoptosis of Bladder Cancer Cells in Vitro
  Pharmacological Research. Nov-Dec, 2008  |   Pubmed ID: 18840529
• Circulating Tumor Cells Predict Survival Benefit from Treatment in Metastatic Castration-resistant Prostate Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2008  |   Pubmed ID: 18829513
• Re: RANKL Inhibition is an Effective Adjuvant for Docetaxel in a Prostate Cancer Bone Metastasis Model
  European Urology. Sep, 2008  |   Pubmed ID: 18792431
• CCL2, Survivin and Autophagy: New Links with Implications in Human Cancer
  Autophagy. Oct, 2008  |   Pubmed ID: 18758234
• Tumor Expressed PTHrP Facilitates Prostate Cancer-induced Osteoblastic Lesions
  International Journal of Cancer. Nov, 2008  |   Pubmed ID: 18729185
• CCL2 Induces Prostate Cancer Transendothelial Cell Migration Via Activation of the Small GTPase Rac
  Journal of Cellular Biochemistry. Aug, 2008  |   Pubmed ID: 18646053
• Annexin II/annexin II Receptor Axis Regulates Adhesion, Migration, Homing, and Growth of Prostate Cancer
  Journal of Cellular Biochemistry. Oct, 2008  |   Pubmed ID: 18636554
• CCL2 Protects Prostate Cancer PC3 Cells from Autophagic Death Via Phosphatidylinositol 3-kinase/AKT-dependent Survivin Up-regulation
  The Journal of Biological Chemistry. Sep, 2008  |   Pubmed ID: 18611860
• CD26/dipeptidyl Peptidase IV Regulates Prostate Cancer Metastasis by Degrading SDF-1/CXCL12
  Clinical & Experimental Metastasis. 2008  |   Pubmed ID: 18563594
• Novel Surface Expression of Reticulocalbin 1 on Bone Endothelial Cells and Human Prostate Cancer Cells is Regulated by TNF-alpha
  Journal of Cellular Biochemistry. Aug, 2008  |   Pubmed ID: 18561328
• Dickkopf-1 Expression Increases Early in Prostate Cancer Development and Decreases During Progression from Primary Tumor to Metastasis
  The Prostate. Sep, 2008  |   Pubmed ID: 18561248
• Characterization of TMPRSS2-ETS Gene Aberrations in Androgen-independent Metastatic Prostate Cancer
  Cancer Research. May, 2008  |   Pubmed ID: 18483239
• An in Vivo Mouse Model for Human Prostate Cancer Metastasis
  Neoplasia (New York, N.Y.). Apr, 2008  |   Pubmed ID: 18392141
• A Sequence-based Survey of the Complex Structural Organization of Tumor Genomes
  Genome Biology. 2008  |   Pubmed ID: 18364049
• Temporal Activation of P53 by a Specific MDM2 Inhibitor is Selectively Toxic to Tumors and Leads to Complete Tumor Growth Inhibition
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2008  |   Pubmed ID: 18316739
• The Current State of Preclinical Prostate Cancer Animal Models
  The Prostate. May, 2008  |   Pubmed ID: 18213636
• The Role of CXCR7/RDC1 As a Chemokine Receptor for CXCL12/SDF-1 in Prostate Cancer
  The Journal of Biological Chemistry. Feb, 2008  |   Pubmed ID: 18057003
• In Vivo Evaluation of AT-101 (R-(-)-gossypol Acetic Acid) in Androgen-independent Growth of VCaP Prostate Cancer Cells in Combination with Surgical Castration
  Neoplasia (New York, N.Y.). Dec, 2007  |   Pubmed ID: 18084610
• A Feasibility Study Evaluating the Functional Diffusion Map As a Predictive Imaging Biomarker for Detection of Treatment Response in a Patient with Metastatic Prostate Cancer to the Bone
  Neoplasia (New York, N.Y.). Dec, 2007  |   Pubmed ID: 18084607
• A Polycomb Repression Signature in Metastatic Prostate Cancer Predicts Cancer Outcome
  Cancer Research. Nov, 2007  |   Pubmed ID: 18006806
• Randomized Clinical Trial of a Family Intervention for Prostate Cancer Patients and Their Spouses
  Cancer. Dec, 2007  |   Pubmed ID: 17999405
• Eleventh Prouts Neck Meeting on Prostate Cancer: Emerging Strategies in Prostate Cancer Therapy
  Cancer Research. Oct, 2007  |   Pubmed ID: 17928375
• Targeting CCL2 with Systemic Delivery of Neutralizing Antibodies Induces Prostate Cancer Tumor Regression in Vivo
  Cancer Research. Oct, 2007  |   Pubmed ID: 17909051
• Integrative Analysis of Genomic Aberrations Associated with Prostate Cancer Progression
  Cancer Research. Sep, 2007  |   Pubmed ID: 17804737
• The Evolving Biology and Treatment of Prostate Cancer
  The Journal of Clinical Investigation. Sep, 2007  |   Pubmed ID: 17786228
• Galectin-3 As a Potential Therapeutic Target in Tumors Arising from Malignant Endothelia
  Neoplasia (New York, N.Y.). Aug, 2007  |   Pubmed ID: 17786185
• CCL2 As an Important Mediator of Prostate Cancer Growth in Vivo Through the Regulation of Macrophage Infiltration
  Neoplasia (New York, N.Y.). Jul, 2007  |   Pubmed ID: 17710158
• A Hierarchical Network of Transcription Factors Governs Androgen Receptor-dependent Prostate Cancer Growth
  Molecular Cell. Aug, 2007  |   Pubmed ID: 17679089
• Distinct Classes of Chromosomal Rearrangements Create Oncogenic ETS Gene Fusions in Prostate Cancer
  Nature. Aug, 2007  |   Pubmed ID: 17671502
• Phase II Evaluation of Oral Estramustine, Oral Etoposide, and Intravenous Paclitaxel in Patients with Hormone-sensitive Prostate Adenocarcinoma
  Clinical Genitourinary Cancer. Jun, 2007  |   Pubmed ID: 17645828
• Living with Prostate Cancer: Patients' and Spouses' Psychosocial Status and Quality of Life
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Sep, 2007  |   Pubmed ID: 17635953
• The Lethal Phenotype of Cancer: the Molecular Basis of Death Due to Malignancy
  CA: a Cancer Journal for Clinicians. Jul-Aug, 2007  |   Pubmed ID: 17626119
• PAR1-mediated RhoA Activation Facilitates CCL2-induced Chemotaxis in PC-3 Cells
  Journal of Cellular Biochemistry. Aug, 2007  |   Pubmed ID: 17492768
• An Imaging Biomarker of Early Treatment Response in Prostate Cancer That Has Metastasized to the Bone
  Cancer Research. Apr, 2007  |   Pubmed ID: 17440058
• Comprehensive Assessment of TMPRSS2 and ETS Family Gene Aberrations in Clinically Localized Prostate Cancer
  Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. May, 2007  |   Pubmed ID: 17334343
• A Glycolytic Mechanism Regulating an Angiogenic Switch in Prostate Cancer
  Cancer Research. Jan, 2007  |   Pubmed ID: 17210694
• Integrative Molecular Concept Modeling of Prostate Cancer Progression
  Nature Genetics. Jan, 2007  |   Pubmed ID: 17173048
• Expression and Activation of Alpha V Beta 3 Integrins by SDF-1/CXC12 Increases the Aggressiveness of Prostate Cancer Cells
  The Prostate. Jan, 2007  |   Pubmed ID: 17034033
• Phase II Trial of Copper Depletion with Tetrathiomolybdate As an Antiangiogenesis Strategy in Patients with Hormone-refractory Prostate Cancer
  Oncology. 2006  |   Pubmed ID: 17641535
• Simulating the Hallmarks of Cancer
  Artificial Life. 2006  |   Pubmed ID: 16953788
• Evolution of Cooperation Among Tumor Cells
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2006  |   Pubmed ID: 16938860
• Modeling Somatic Evolution in Tumorigenesis
  PLoS Computational Biology. Aug, 2006  |   Pubmed ID: 16933983
• CCL2 is a Potent Regulator of Prostate Cancer Cell Migration and Proliferation
  Neoplasia (New York, N.Y.). Jul, 2006  |   Pubmed ID: 16867220
• Prostate Cancer Presenting As Visual Changes
  Anticancer Research. Jan-Feb, 2006  |   Pubmed ID: 16739349
• Phase II Evaluations of Cilengitide in Asymptomatic Patients with Androgen-independent Prostate Cancer: Scientific Rationale and Study Design
  Clinical Genitourinary Cancer. Mar, 2006  |   Pubmed ID: 16729916
• Dose Escalation of Oral Vinorelbine in Combination with Estramustine in Hormone-refractory Adenocarcinoma of the Prostate
  Cancer. Jun, 2006  |   Pubmed ID: 16691618
• Mechanisms Underlying the Development of Androgen-independent Prostate Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2006  |   Pubmed ID: 16551847
• Phase II Trial of Oral Uracil/tegafur Plus Leucovorin in Patients with Hormone-refractory Prostate Carcinoma
  Cancer. Apr, 2006  |   Pubmed ID: 16534795
• Inhibition of Decay-accelerating Factor (CD55) Attenuates Prostate Cancer Growth and Survival in Vivo
  Neoplasia (New York, N.Y.). Jan, 2006  |   Pubmed ID: 16533428
• Development of the VCaP Androgen-independent Model of Prostate Cancer
  Urologic Oncology. Mar-Apr, 2006  |   Pubmed ID: 16520280
• GREB1 is a Novel Androgen-regulated Gene Required for Prostate Cancer Growth
  The Prostate. Jun, 2006  |   Pubmed ID: 16496412
• Drug Insight: Use of Docetaxel in Prostate and Urothelial Cancers
  Nature Clinical Practice. Urology. Feb, 2005  |   Pubmed ID: 16474654
• Radiation Therapy Oncology Group 0521: a Phase III Randomized Trial of Androgen Suppression and Radiation Therapy Versus Androgen Suppression and Radiation Therapy Followed by Chemotherapy with Docetaxel/prednisone for Localized, High-risk Prostate Cancer
  Clinical Genitourinary Cancer. Dec, 2005  |   Pubmed ID: 16425991
• Analysis of Membrane-bound Complement Regulatory Proteins in Prostate Cancer
  Urology. Dec, 2005  |   Pubmed ID: 16360477
• Integrative Genomic and Proteomic Analysis of Prostate Cancer Reveals Signatures of Metastatic Progression
  Cancer Cell. Nov, 2005  |   Pubmed ID: 16286247
• Pathogenesis and Treatment of Prostate Cancer Bone Metastases: Targeting the Lethal Phenotype
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Nov, 2005  |   Pubmed ID: 16278478
• Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
  Science (New York, N.Y.). Oct, 2005  |   Pubmed ID: 16254181
• Autoantibody Signatures in Prostate Cancer
  The New England Journal of Medicine. Sep, 2005  |   Pubmed ID: 16177248
• Advances in Prostate Cancer Chemotherapy: a New Era Begins
  CA: a Cancer Journal for Clinicians. Sep-Oct, 2005  |   Pubmed ID: 16166075
• Osteonecrosis of Jaw in Patient with Hormone-refractory Prostate Cancer Treated with Zoledronic Acid
  Urology. Sep, 2005  |   Pubmed ID: 16140106
• Proptosis and Decreased Vision Secondary to Prostate Cancer Orbital Wall Metastasis
  Anticancer Research. Sep-Oct, 2005  |   Pubmed ID: 16101173
• Amplification and Overexpression of Prosaposin in Prostate Cancer
  Genes, Chromosomes & Cancer. Dec, 2005  |   Pubmed ID: 16080200
• Androgens and Prostate Cancer: Are the Descriptors Valid?
  Cancer Biology & Therapy. Jan, 2005  |   Pubmed ID: 16052746
• PAR1-mediated NFkappaB Activation Promotes Survival of Prostate Cancer Cells Through a Bcl-xL-dependent Mechanism
  Journal of Cellular Biochemistry. Oct, 2005  |   Pubmed ID: 16052512
• Identification of Leukocyte E-selectin Ligands, P-selectin Glycoprotein Ligand-1 and E-selectin Ligand-1, on Human Metastatic Prostate Tumor Cells
  Cancer Research. Jul, 2005  |   Pubmed ID: 15994950
• The "emigration, Migration, and Immigration"of Prostate Cancer
  Clinical Prostate Cancer. Jun, 2005  |   Pubmed ID: 15992458
• A Paradigm for the Treatment of Prostate Cancer Bone Metastases Based on an Understanding of Tumor Cell-microenvironment Interactions
  Journal of Cellular Biochemistry. Oct, 2005  |   Pubmed ID: 15988761
• Mechanical Entrapment is Insufficient and Intercellular Adhesion is Essential for Metastatic Cell Arrest in Distant Organs
  Neoplasia (New York, N.Y.). May, 2005  |   Pubmed ID: 15967104
• Global Gene Expression Profiling of Circulating Tumor Cells
  Cancer Research. Jun, 2005  |   Pubmed ID: 15958538
• Differential Expression Analysis of MIM (MTSS1) Splice Variants and a Functional Role of MIM in Prostate Cancer Cell Biology
  International Journal of Oncology. Jun, 2005  |   Pubmed ID: 15870888
• Skeletal Localization and Neutralization of the SDF-1(CXCL12)/CXCR4 Axis Blocks Prostate Cancer Metastasis and Growth in Osseous Sites in Vivo
  Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Feb, 2005  |   Pubmed ID: 15647826
• Bone Turnover Mediates Preferential Localization of Prostate Cancer in the Skeleton
  Endocrinology. Apr, 2005  |   Pubmed ID: 15637291
• Androgen-independent Prostate Cancer is a Heterogeneous Group of Diseases: Lessons from a Rapid Autopsy Program
  Cancer Research. Dec, 2004  |   Pubmed ID: 15604294
• Expression and Regulation of MIM (Missing In Metastasis), a Novel Putative Metastasis Suppressor Gene, and MIM-B, in Bladder Cancer Cell Lines
  Cancer Letters. Nov, 2004  |   Pubmed ID: 15488640
• Rationale for the Radiation Therapy Oncology Group Study RTOG P-0014
  Reviews in Urology. 2003  |   Pubmed ID: 16986043
• Rationale for the Radiation Therapy Oncology Group Study RTOG P-0014
  Reviews in Urology. 2003  |   Pubmed ID: 16985950