Khalid Salaita Department of Chemistry Emory University Biography Publications Institution JoVE Articles Khalid Salaita has not added a biography. If you are Khalid Salaita and would like to personalize this page please email our Author Liaison for assistance. Publications Spectroscopic Analysis of a Library of DNA Tension Probes for Mapping Cellular Forces at Fluid Interfaces ACS Applied Materials & Interfaces. Jan, 2021 | Pubmed ID: 33417432 Multivalent Molecular Tension Probes As Anisotropic Mechanosensors: Concept and Simulation Physical Biology. Mar, 2021 | Pubmed ID: 33316784 Shape-Shifting Peptide Nanomaterials: Surface Asymmetry Enables PH-Dependent Formation and Interconversion of Collagen Tubes and Sheets Journal of the American Chemical Society. 11, 2020 | Pubmed ID: 33170675 Live-cell Super-resolved PAINT Imaging of Piconewton Cellular Traction Forces Nature Methods. 10, 2020 | Pubmed ID: 32929270 Conditional Deoxyribozyme-Nanoparticle Conjugates for MiRNA-Triggered Gene Regulation ACS Applied Materials & Interfaces. Aug, 2020 | Pubmed ID: 32803952 Mechanical Stimulation of Adhesion Receptors Using Light-Responsive Nanoparticle Actuators Enhances Myogenesis ACS Applied Materials & Interfaces. Aug, 2020 | Pubmed ID: 32644776 EGFR Activation Attenuates the Mechanical Threshold for Integrin Tension and Focal Adhesion Formation Journal of Cell Science. 07, 2020 | Pubmed ID: 32546532 Super-Resolution Fluorescence Imaging Reveals That Serine Incorporator Protein 5 Inhibits Human Immunodeficiency Virus Fusion by Disrupting Envelope Glycoprotein Clusters ACS Nano. 09, 2020 | Pubmed ID: 32441921 Optical Control of Cytokine Signaling Via Bioinspired, Polymer-Induced Latency Biomacromolecules. 07, 2020 | Pubmed ID: 32374589 Engineering DNA-Functionalized Nanostructures to Bind Nucleic Acid Targets Heteromultivalently with Enhanced Avidity Journal of the American Chemical Society. 05, 2020 | Pubmed ID: 32338896 Tunable DNA Origami Motors Translocate Ballistically Over μm Distances at Nm/s Speeds Angewandte Chemie (International Ed. in English). 06, 2020 | Pubmed ID: 32017312 Forces During Cellular Uptake of Viruses and Nanoparticles at the Ventral Side Nature Communications. 01, 2020 | Pubmed ID: 31896744 Seeded Heteroepitaxial Growth of Crystallizable Collagen Triple Helices: Engineering Multifunctional Two-Dimensional Core-Shell Nanostructures Journal of the American Chemical Society. 12, 2019 | Pubmed ID: 31800228 DNA Mechanotechnology Reveals That Integrin Receptors Apply PN Forces in Podosomes on Fluid Substrates Nature Communications. 10, 2019 | Pubmed ID: 31628308 Emerging Uses of DNA Mechanical Devices Science (New York, N.Y.). 09, 2019 | Pubmed ID: 31515373 Chameleon-Inspired Strain-Accommodating Smart Skin ACS Nano. 09, 2019 | Pubmed ID: 31507164 Highly Polyvalent DNA Motors Generate 100+ PN of Force Via Autochemophoresis Nano Letters. 10, 2019 | Pubmed ID: 31402671 DNA Probes That Store Mechanical Information Reveal Transient Piconewton Forces Applied by T Cells Proceedings of the National Academy of Sciences of the United States of America. 08, 2019 | Pubmed ID: 31391300 Macrophages Exposed to HIV Viral Protein Disrupt Lung Epithelial Cell Integrity and Mitochondrial Bioenergetics Via Exosomal MicroRNA Shuttling Cell Death & Disease. 08, 2019 | Pubmed ID: 31371699 Mechanical Proofreading: A General Mechanism to Enhance the Fidelity of Information Transfer Between Cells Frontiers in Physics. Feb, 2019 | Pubmed ID: 31328129 2D Crystal Engineering of Nanosheets Assembled from Helical Peptide Building Blocks Angewandte Chemie (International Ed. in English). 09, 2019 | Pubmed ID: 31291499 DNA Nanotechnology As an Emerging Tool to Study Mechanotransduction in Living Systems Small (Weinheim an Der Bergstrasse, Germany). 06, 2019 | Pubmed ID: 31069945 Localized Nanoscale Heating Leads to Ultrafast Hydrogel Volume-Phase Transition ACS Nano. 01, 2019 | Pubmed ID: 30574782 A TCR Mechanotransduction Signaling Loop Induces Negative Selection in the Thymus Nature Immunology. 12, 2018 | Pubmed ID: 30420628 Location, Location, Location: EphB4:Ephrin-B2 Signaling Depends on Its Spatial Arrangement Biophysical Journal. 09, 2018 | Pubmed ID: 30082034 A Brighter Force Gauge for Cells ELife. 07, 2018 | Pubmed ID: 30024375 Programmable Multivalent DNA-Origami Tension Probes for Reporting Cellular Traction Forces Nano Letters. 08, 2018 | Pubmed ID: 29911385 Molecular Tension Probes to Investigate the Mechanopharmacology of Single Cells: A Step Toward Personalized Mechanomedicine Advanced Healthcare Materials. 07, 2018 | Pubmed ID: 29785773 Light-Responsive Polymer Particles As Force Clamps for the Mechanical Unfolding of Target Molecules Nano Letters. 04, 2018 | Pubmed ID: 29589759 Platelet Integrins Exhibit Anisotropic Mechanosensing and Harness Piconewton Forces to Mediate Platelet Aggregation Proceedings of the National Academy of Sciences of the United States of America. 01, 2018 | Pubmed ID: 29269394 Mapping the 3D Orientation of Piconewton Integrin Traction Forces Nature Methods. 02, 2018 | Pubmed ID: 29256495 Site-Selective RNA Splicing Nanozyme: DNAzyme and RtcB Conjugates on a Gold Nanoparticle ACS Chemical Biology. 01, 2018 | Pubmed ID: 29155548 Molecular Tension Probes for Imaging Forces at the Cell Surface Accounts of Chemical Research. 12, 2017 | Pubmed ID: 29160067 Supported Lipid Bilayer Platforms to Probe Cell Mechanobiology Biochimica Et Biophysica Acta. Biomembranes. Sep, 2017 | Pubmed ID: 28502789 Ratiometric Tension Probes for Mapping Receptor Forces and Clustering at Intermembrane Junctions Nano Letters. 07, 2016 | Pubmed ID: 27192323 DNA-based Nanoparticle Tension Sensors Reveal That T-cell Receptors Transmit Defined PN Forces to Their Antigens for Enhanced Fidelity Proceedings of the National Academy of Sciences of the United States of America. May, 2016 | Pubmed ID: 27140637 Mechanically Induced Catalytic Amplification Reaction for Readout of Receptor-Mediated Cellular Forces Angewandte Chemie (International Ed. in English). 04, 2016 | Pubmed ID: 27038115 A General Approach for Generating Fluorescent Probes to Visualize Piconewton Forces at the Cell Surface Journal of the American Chemical Society. Mar, 2016 | Pubmed ID: 26871302 Knockdown of TNF-α by DNAzyme Gold Nanoparticles As an Anti-inflammatory Therapy for Myocardial Infarction Biomaterials. Mar, 2016 | Pubmed ID: 26773660 Nanoscale Optomechanical Actuators for Controlling Mechanotransduction in Living Cells Nature Methods. Feb, 2016 | Pubmed ID: 26657558 High-speed DNA-based Rolling Motors Powered by RNase H Nature Nanotechnology. Feb, 2016 | Pubmed ID: 26619152 Titin-Based Nanoparticle Tension Sensors Map High-Magnitude Integrin Forces Within Focal Adhesions Nano Letters. Jan, 2016 | Pubmed ID: 26598972 Real-time Fluorescence Imaging with 20 nm Axial Resolution Nature Communications. Sep, 2015 | Pubmed ID: 26392382 Lighting Up the Force: Investigating Mechanisms of Mechanotransduction Using Fluorescent Tension Probes Molecular and Cellular Biology. Aug, 2015 | Pubmed ID: 26031334 DNA-based Digital Tension Probes Reveal Integrin Forces During Early Cell Adhesion Nature Communications. Oct, 2014 | Pubmed ID: 25342432 Nanoparticle Tension Probes Patterned at the Nanoscale: Impact of Integrin Clustering on Force Transmission Nano Letters. Oct, 2014 | Pubmed ID: 25238229 The Modulation of Cardiac Progenitor Cell Function by Hydrogel-dependent Notch1 Activation Biomaterials. Sep, 2014 | Pubmed ID: 24974008 Integrin-generated Forces Lead to Streptavidin-biotin Unbinding in Cellular Adhesions Biophysical Journal. Apr, 2014 | Pubmed ID: 24703305 Structurally Defined Nanoscale Sheets from Self-assembly of Collagen-mimetic Peptides Journal of the American Chemical Society. Mar, 2014 | Pubmed ID: 24571053 Quantum Dots Encapsulated Within Phospholipid Membranes: Phase-dependent Structure, Photostability, and Site-selective Functionalization Journal of the American Chemical Society. Feb, 2014 | Pubmed ID: 24417287 Membrane Tethered Delta Activates Notch and Reveals a Role for Spatio-mechanical Regulation of the Signaling Pathway Biophysical Journal. Dec, 2013 | Pubmed ID: 24359737 Tension Sensing Nanoparticles for Mechano-imaging at the Living/nonliving Interface Journal of the American Chemical Society. Apr, 2013 | Pubmed ID: 23495954 Catalytic Deoxyribozyme-modified Nanoparticles for RNAi-independent Gene Regulation ACS Nano. Oct, 2012 | Pubmed ID: 22966955 Visualizing Mechanical Tension Across Membrane Receptors with a Fluorescent Sensor Nature Methods. Oct, 2011 | Pubmed ID: 22037704 L-Ala-γ-D-Glu-meso-diaminopimelic Acid (DAP) Interacts Directly with Leucine-rich Region Domain of Nucleotide-binding Oligomerization Domain 1, Increasing Phosphorylation Activity of Receptor-interacting Serine/threonine-protein Kinase 2 and Its Interaction with Nucleotide-binding Oligomerization Domain 1 The Journal of Biological Chemistry. Sep, 2011 | Pubmed ID: 21757725 Using Patterned Supported Lipid Membranes to Investigate the Role of Receptor Organization in Intercellular Signaling Nature Protocols. Apr, 2011 | Pubmed ID: 21455188 Nanomedicine in GI American Journal of Physiology. Gastrointestinal and Liver Physiology. Mar, 2011 | Pubmed ID: 21148398 Roles of the Cytoskeleton in Regulating EphA2 Signals Communicative & Integrative Biology. Sep, 2010 | Pubmed ID: 21057639 DNA Tension Probes to Map the Transient Piconewton Receptor Forces by Immune Cells Rong Ma1, Anna V. Kellner2, Yuesong Hu1, Brendan R. Deal1, Aaron T. Blanchard2, Khalid Salaita1,2 1Department of Chemistry, Emory University, 2Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University JoVE 62348 Bioengineering
DNA Tension Probes to Map the Transient Piconewton Receptor Forces by Immune Cells Rong Ma1, Anna V. Kellner2, Yuesong Hu1, Brendan R. Deal1, Aaron T. Blanchard2, Khalid Salaita1,2 1Department of Chemistry, Emory University, 2Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University JoVE 62348 Bioengineering
