Kirill Gorshkov

Publications

• C-Abl Activation Linked to Autophagy-Lysosomal Dysfunction Contributes to Neurological Impairment in Niemann-Pick Type A Disease
  Frontiers in Cell and Developmental Biology. 2022  |   Pubmed ID: 35399514
• A High Throughput Screening Assay for Inhibitors of SARS-CoV-2 Pseudotyped Particle Entry
  SLAS Discovery : Advancing Life Sciences R & D. 03, 2022  |   Pubmed ID: 35086793
• SARS-CoV-2 Nucleocapsid Protein TR-FRET Assay Amenable to High Throughput Screening
  ACS Pharmacology & Translational Science. Jan, 2022  |   Pubmed ID: 35036857
• Fluorescent Quantum Dots Enable SARS-CoV-2 Antiviral Drug Discovery and Development
  Expert Opinion on Drug Discovery. 03, 2022  |   Pubmed ID: 34817309
• A High Throughput Screening Assay for Inhibitors of SARS-CoV-2 Pseudotyped Particle Entry
  BioRxiv : the Preprint Server for Biology. Oct, 2021  |   Pubmed ID: 34642691
• A SARS-CoV-2 Nucleocapsid Protein TR-FRET Assay Amenable to High-throughput Screening
  BioRxiv : the Preprint Server for Biology. Jul, 2021  |   Pubmed ID: 34268508
• Generation of an Induced Pluripotent Stem Cell Line (TRNDi031-A) from a Patient with Alagille Syndrome Type 1 Carrying a Heterozygous P. C312X (c. 936 T > A) Mutation in JAGGED-1
  Stem Cell Research. 07, 2021  |   Pubmed ID: 34198154
• Generation of an Induced Pluripotent Stem Cell Line (TRNDi030-A) from a Patient with Farber Disease Carrying a Homozygous P. Y36C (c. 107 A>G) Mutation in ASAH1
  Stem Cell Research. 05, 2021  |   Pubmed ID: 34088014
• Enrichment of NPC1-deficient Cells with the Lipid LBPA Stimulates Autophagy, Improves Lysosomal Function, and Reduces Cholesterol Storage
  The Journal of Biological Chemistry. 07, 2021  |   Pubmed ID: 34023384
• The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules
  ACS Infectious Diseases. 06, 2021  |   Pubmed ID: 33346633
• Zika Virus-Induced Neuronal Apoptosis Via Increased Mitochondrial Fragmentation
  Frontiers in Microbiology. 2020  |   Pubmed ID: 33424801
• CircRNA-SORE Mediates Sorafenib Resistance in Hepatocellular Carcinoma by Stabilizing YBX1
  Signal Transduction and Targeted Therapy. 12, 2020  |   Pubmed ID: 33361760
• Development of a High-Throughput Homogeneous AlphaLISA Drug Screening Assay for the Detection of SARS-CoV-2 Nucleocapsid
  ACS Pharmacology & Translational Science. Dec, 2020  |   Pubmed ID: 33330840
• Identifying SARS-CoV-2 Entry Inhibitors Through Drug Repurposing Screens of SARS-S and MERS-S Pseudotyped Particles
  ACS Pharmacology & Translational Science. Dec, 2020  |   Pubmed ID: 33330839
• N-methyladenosine-modified CircRNA-SORE Sustains Sorafenib Resistance in Hepatocellular Carcinoma by Regulating β-catenin Signaling
  Molecular Cancer. 11, 2020  |   Pubmed ID: 33222692
• Quantum Dot-Conjugated SARS-CoV-2 Spike Pseudo-Virions Enable Tracking of Angiotensin Converting Enzyme 2 Binding and Endocytosis
  ACS Nano. 09, 2020  |   Pubmed ID: 32845122
• Development of a High-throughput Homogeneous AlphaLISA Drug Screening Assay for the Detection of SARS-CoV-2 Nucleocapsid
  BioRxiv : the Preprint Server for Biology. Aug, 2020  |   Pubmed ID: 32839774
• Drug Discovery Strategies for SARS-CoV-2
  The Journal of Pharmacology and Experimental Therapeutics. 10, 2020  |   Pubmed ID: 32723801
• RNA-Dependent RNA Polymerase As a Target for COVID-19 Drug Discovery
  SLAS Discovery : Advancing Life Sciences R & D. 12, 2020  |   Pubmed ID: 32660307
• Cell-Based No-Wash Fluorescence Assays for Compound Screens Using a Fluorescence Cytometry Plate Reader
  The Journal of Pharmacology and Experimental Therapeutics. 09, 2020  |   Pubmed ID: 32532853
• An OpenData Portal to Share COVID-19 Drug Repurposing Data in Real Time
  BioRxiv : the Preprint Server for Biology. Jun, 2020  |   Pubmed ID: 32511420
• The SARS-CoV-2 Cytopathic Effect is Blocked with Autophagy Modulators
  BioRxiv : the Preprint Server for Biology. May, 2020  |   Pubmed ID: 32511355
• Phosphocyclocreatine is the Dominant Form of Cyclocreatine in Control and Creatine Transporter Deficiency Patient Fibroblasts
  Pharmacology Research & Perspectives. 12, 2019  |   Pubmed ID: 31859463
• Identification of Ezetimibe and Pranlukast As Pharmacological Chaperones for the Treatment of the Rare Disease Mucopolysaccharidosis Type IVA
  Journal of Medicinal Chemistry. 07, 2019  |   Pubmed ID: 31188588
• Induced Pluripotent Stem Cells for Neural Drug Discovery
  Drug Discovery Today. 04, 2019  |   Pubmed ID: 30664937
• Quantitative Chemotherapeutic Profiling of Gynecologic Cancer Cell Lines Using Approved Drugs and Bioactive Compounds
  Translational Oncology. Mar, 2019  |   Pubmed ID: 30576957
• Advancing Precision Medicine with Personalized Drug Screening
  Drug Discovery Today. 01, 2019  |   Pubmed ID: 30125678
• Zika Virus: Origins, Pathological Action, and Treatment Strategies
  Frontiers in Microbiology. 2018  |   Pubmed ID: 30666246
• Neural Stem Cells for Disease Modeling and Evaluation of Therapeutics for Tay-Sachs Disease
  Orphanet Journal of Rare Diseases. 09, 2018  |   Pubmed ID: 30220252
• Small Molecules Identified from a Quantitative Drug Combinational Screen Resensitize Cisplatin's Response in Drug-Resistant Ovarian Cancer Cells
  Translational Oncology. Aug, 2018  |   Pubmed ID: 29982103
• A Biosensor for MAPK-dependent Lin28 Signaling
  Molecular Biology of the Cell. 05, 2018  |   Pubmed ID: 29540527
• Astrocytes As Targets for Drug Discovery
  Drug Discovery Today. 03, 2018  |   Pubmed ID: 29317338