Klaus Eyer Laboratory for Functional Immune Repertoire Analysis, Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences ETH Zürich Biography Publications Institution JoVE Articles Klaus Eyer has not added a biography. If you are Klaus Eyer and would like to personalize this page please email our Author Liaison for assistance. Publications Antibodies, Repertoires and Microdevices in Antibody Discovery and Characterization Lab on a Chip. Feb, 2024 | Pubmed ID: 38165819 Single-cell Deep Phenotyping of Cytokine Release Unmasks Stimulation-specific Biological Signatures and Distinct Secretion Dynamics Cell Reports Methods. Jul, 2023 | Pubmed ID: 37533643 Insights into the Relationship Between Persistent Antibody Secretion and Metabolic Programming - A Question for Single-cell Analysis Immunology Letters. Aug, 2023 | Pubmed ID: 37315849 High-affinity Autoreactive Plasma Cells Disseminate Through Multiple Organs in Patients with Immune Thrombocytopenic Purpura The Journal of Clinical Investigation. Jun, 2022 | Pubmed ID: 35503254 An Automated Real-time Microfluidic Platform to Probe Single NK Cell Heterogeneity and Cytotoxicity On-chip Scientific Reports. 08, 2021 | Pubmed ID: 34429486 Measuring Single-cell Protein Secretion in Immunology: Technologies, Advances, and Applications European Journal of Immunology. Jun, 2021 | Pubmed ID: 33734428 Author Correction: Dynamic Single-cell Phenotyping of Immune Cells Using the Microfluidic Platform DropMap Nature Protocols. Aug, 2021 | Pubmed ID: 33442054 Deep Phenotypic Characterization of Immunization-induced Antibacterial IgG Repertoires in Mice Using a Single-antibody Bioassay Communications Biology. Oct, 2020 | Pubmed ID: 33106526 One by One - Insights into Complex Immune Responses Through Functional Single-cell Analysis Chimia. Sep, 2020 | Pubmed ID: 32958110 Dynamic Single-cell Phenotyping of Immune Cells Using the Microfluidic Platform DropMap Nature Protocols. Sep, 2020 | Pubmed ID: 32788719 The Quantitative Assessment of the Secreted IgG Repertoire After Recall to Evaluate the Quality of Immunizations Journal of Immunology (Baltimore, Md. : 1950). Aug, 2020 | Pubmed ID: 32669311 The Impact of Frost-damage on the Quality and Quantity of the Secreted Antigen-specific IgG Repertoire Vaccine. Jul, 2020 | Pubmed ID: 32571724 Quantitative Modeling of the Effect of Antigen Dosage on B-cell Affinity Distributions in Maturating Germinal Centers ELife. Jun, 2020 | Pubmed ID: 32538783 Author Correction: High-throughput Single-cell Activity-based Screening and Sequencing of Antibodies Using Droplet Microfluidics Nature Biotechnology. Jun, 2020 | Pubmed ID: 32444853 High-throughput Single-cell Activity-based Screening and Sequencing of Antibodies Using Droplet Microfluidics Nature Biotechnology. Jun, 2020 | Pubmed ID: 32231335 Quantitative and Qualitative Analysis of Humoral Immunity Reveals Continued and Personalized Evolution in Chronic Viral Infection Cell Reports. Jan, 2020 | Pubmed ID: 31995768 In Vitro Quantification of Botulinum Neurotoxin Type A1 Using Immobilized Nerve Cell-mimicking Nanoreactors in a Microfluidic Platform The Analyst. Sep, 2019 | Pubmed ID: 31433410 A Microfluidic Device for the Delivery of Enzymes into Cells by Liposome Fusion Engineering in Life Sciences. Feb, 2018 | Pubmed ID: 29416447 Differential Isotope Labeling of Glycopeptides for Accurate Determination of Differences in Site-Specific Glycosylation Journal of Proteome Research. Jan, 2016 | Pubmed ID: 26573365 Detection of Infertility-related Neutralizing Antibodies with a Cell-free Microfluidic Method Scientific Reports. 2015 | Pubmed ID: 26585778 Interaction of β(3) /β(2) -peptides, Consisting of Val-Ala-Leu Segments, with POPC Giant Unilamellar Vesicles (GUVs) and White Blood Cancer Cells (U937)--a New Type of Cell-penetrating Peptides, and a Surprising Chain-length Dependence of Their Vesicle- and Cell-lysing Activity Chemistry & Biodiversity. May, 2015 | Pubmed ID: 26010661 On-chip Enzyme Quantification of Single Escherichia Coli Bacteria by Immunoassay-based Analysis Analytical Chemistry. Dec, 2014 | Pubmed ID: 25409480 Cell-free Microfluidic Determination of P-glycoprotein Interactions with Substrates and Inhibitors Pharmaceutical Research. Dec, 2014 | Pubmed ID: 24928366 Quantification of Saquinavir from Lysates of Peripheral Blood Mononuclear Cells Using Microarrays and Standard MALDI-TOF-MS Journal of the American Society for Mass Spectrometry. Jun, 2014 | Pubmed ID: 24711229 A Liposomal Fluorescence Assay to Study Permeation Kinetics of Drug-like Weak Bases Across the Lipid Bilayer Journal of Controlled Release : Official Journal of the Controlled Release Society. Jan, 2014 | Pubmed ID: 24211703 Enantiomeric and Diastereoisomeric (mixed) L/ D-octaarginine Derivatives - a Simple Way of Modulating the Properties of Cell-penetrating Peptides Chemistry & Biodiversity. Jul, 2013 | Pubmed ID: 23847063 Full Spectroscopic Tip-enhanced Raman Imaging of Single Nanotapes Formed from β-amyloid(1-40) Peptide Fragments ACS Nano. Feb, 2013 | Pubmed ID: 23311496 Interfacing Droplet Microfluidics with Matrix-assisted Laser Desorption/ionization Mass Spectrometry: Label-free Content Analysis of Single Droplets Analytical Chemistry. Feb, 2013 | Pubmed ID: 23289755 A Facile Protocol for the Immobilisation of Vesicles, Virus Particles, Bacteria, and Yeast Cells Integrative Biology : Quantitative Biosciences from Nano to Macro. Dec, 2012 | Pubmed ID: 23147942 A New Mechanobiological Era: Microfluidic Pathways to Apply and Sense Forces at the Cellular Level Current Opinion in Chemical Biology. Aug, 2012 | Pubmed ID: 22525494 A Microchamber Array for Single Cell Isolation and Analysis of Intracellular Biomolecules Lab on a Chip. Feb, 2012 | Pubmed ID: 22183159 A Microfluidic Vesicle Screening Platform: Monitoring the Lipid Membrane Permeability of Tetracyclines Analytical Chemistry. Dec, 2011 | Pubmed ID: 22010628 Author Spotlight: Unveiling the Polyfunctionality and Heterogeneity in Immune Responses Aline Linder*1, Kevin Portmann*1, Luca Johannes Schlotheuber1, Alessandro Streuli1, Wiona Sophie Glänzer1, Klaus Eyer1,2, Ines Lüchtefeld1,3 1Laboratory for Functional Immune Repertoire Analysis, Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zürich, 2Department of Biomedicine, Aarhus University, 3Laboratory for Tumor and Stem Cell Dynamics, Institute of Molecular Health Sciences, Department of Biology, ETH Zürich JoVE 66492 Immunology and Infection A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells Klaus Eyer1, Phillip Kuhn1, Simone Stratz1, Petra S Dittrich1 1Department of Chemistry and Applied Biosciences, ETH Zurich, Switzerland JoVE 50618 Bioengineering
Author Spotlight: Unveiling the Polyfunctionality and Heterogeneity in Immune Responses Aline Linder*1, Kevin Portmann*1, Luca Johannes Schlotheuber1, Alessandro Streuli1, Wiona Sophie Glänzer1, Klaus Eyer1,2, Ines Lüchtefeld1,3 1Laboratory for Functional Immune Repertoire Analysis, Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zürich, 2Department of Biomedicine, Aarhus University, 3Laboratory for Tumor and Stem Cell Dynamics, Institute of Molecular Health Sciences, Department of Biology, ETH Zürich JoVE 66492 Immunology and Infection
A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells Klaus Eyer1, Phillip Kuhn1, Simone Stratz1, Petra S Dittrich1 1Department of Chemistry and Applied Biosciences, ETH Zurich, Switzerland JoVE 50618 Bioengineering
