Koji Furukawa Biomedical Research Institute National Institute of Advanced Industrial Science and Technology (AIST) Biography Publications Institution JoVE Articles Koji Furukawa has not added a biography. If you are Koji Furukawa and would like to personalize this page please email our Author Liaison for assistance. Publications Crystal structures of FMN-bound and FMN-free forms of dihydroorotate dehydrogenase from Trypanosoma bruceiFebs Open Bio. 2018 | Pubmed ID: An NMR Biochemical Assay for Fragment-Based Drug Discovery: Evaluation of an Inhibitor Activity on Spermidine Synthase of Trypanosoma cruziJournal of Medicinal Chemistry. 2016 | Pubmed ID: CD72 negatively regulates B lymphocyte responses to the lupus-related endogenous toll-like receptor 7 ligand Sm/RNPJournal of Experimental Medicine. 2016 | Pubmed ID: Inositol 1,4,5-trisphosphate receptor determines intracellular Ca2+ concentration in Trypanosoma cruzi throughout its life cycleFebs Open Bio. 2016 | Pubmed ID: Both mutated and unmutated memory B cells accumulate mutations in the course of the secondary response and develop a new antibody repertoireoptimally adapted to the secondary stimulusInternational Immunology. 2013 | Pubmed ID: Repression of the Transcription Factor Bach2 Contributes to Predisposition of IgG1 Memory B Cells toward Plasma Cell DifferentiationImmunity. 2013 | Pubmed ID: Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese populationInternational Journal of Hematology. 2011 | Pubmed ID: Conformational analysis of human serum albumin and its non-enzymatic glycation products using monoclonal antibodiesJournal of Biochemistry. 2011 | Pubmed ID: Augmented Antibody Response with Premature Germinal Center Regression in CD40L Transgenic MiceJournal of Immunology. 2010 | Pubmed ID: An optimized procedure for efficient phage display of antibody fragments with a low folding efficiencyProtein Expression and Purification. 2009 | Pubmed ID: Efficient bacterial production of functional antibody fragments using a phagemid vectorProtein Expression and Purification. 2008 | Pubmed ID: Strategy for affinity maturation of an antibody with high evolvability to (4-hydroxy-3-nitrophenyl) acetyl haptenMolecular Immunology. 2007 | Pubmed ID: T cells specific to hapten-carrier but not to carrier alone assist in the production of anti-hapten and anti-carrier antibodiesInternational Immunology. 2007 | Pubmed ID: Initial repertoire of anti-(4-hydroxy-3-nitrophenylacetyl) antibodies as potential donors for effective affinity maturationMolecular Immunology. 2006 | Pubmed ID: A landscape for the dynamics of an immune responseBiochemical and Biophysical Research Communications. 2004 | Pubmed ID: BASH-deficient mice: limited primary repertoire and antibody formation, but sufficient affinity maturation and memory B cell generation, inanti-NP responseInternational Immunology. 2004 | Pubmed ID: Thermodynamic and kinetic aspects of antibody evolution during the immune response to haptenMolecular Immunology. 2003 | Pubmed ID: A role of the third complementarity-determining region in the affinity maturation of an antibodyJournal of Biological Chemistry. 2001 | Pubmed ID: Construction of an artificial tandem protein of the c-Myb DNA-binding domain and analysis of its DNA binding specificityBiochemical and Biophysical Research Communications. 1999 | Pubmed ID: Junctional amino acids determine the maturation pathway of an antibodyImmunity. 1999 | Pubmed ID: Kinetic analysis of DNA binding by the c-Myb DNA-binding domain using surface plasmon resonanceFebs Letters. 1999 | Pubmed ID: Thermodynamic analysis of protein induced folding upon DNA bindingOld and New Views of Protein Folding. 1999 | Pubmed ID: Thermodynamics of specific and non-specific DNA binding by the c-Myb DNA-binding domainJournal of Molecular Biology. 1998 | Pubmed ID: Identification of indispensable residues for specific DNA-binding in the imperfect tandem repeats of c-Myb R2R3Protein Engineering. 1997 | Pubmed ID: Residue 187 in c-Myb DNA-binding domain has a role to recognize the first pyrimidine in the consensus DNA sequenceProtein Engineering. 1997 | Pubmed ID: A small engineered protein lacks structural uniqueness by increasing the side-chain conformational entropyProceedings of the National Academy of Sciences of the United States of America. 1996 | Pubmed ID: IDENTIFICATION OF LYS(277) AT THE ACTIVE-SITE OF ESCHERICHIA-COLI GLYCOGEN-SYNTHASE - APPLICATION OF AFFINITY LABELING COMBINED WITHSITE-DIRECTED MUTAGENESISJournal of Biological Chemistry. 1994 | Pubmed ID: ROLE OF THE CONSERVED LYS-X-GLY-GLY SEQUENCE AT THE ADP-GLUCOSE-BINDING SITE IN ESCHERICHIA-COLI GLYCOGEN-SYNTHASEJournal of Biological Chemistry. 1993 | Pubmed ID: PROBING THE ACTIVE-SITE IN GLYCOGEN-SYNTHASE BY AFFINITY LABELING WITH NUCLEOTIDYL DERIVATIVES OF PYRIDOXAL-PHOSPHATEEnzymes Dependent on Pyridoxal Phosphate and Other Carbonyl Compounds As Cofactors. 1991 | Pubmed ID: IDENTIFICATION OF LYSINE-15 AT THE ACTIVE-SITE IN ESCHERICHIA-COLI GLYCOGEN-SYNTHASE - CONSERVATION OF A LYS-X-GLY-GLY SEQUENCE IN THEBACTERIAL AND MAMMALIAN ENZYMESJournal of Biological Chemistry. 1990 | Pubmed ID: FIBRINOGEN NAGOYA, A REPLACEMENT OF GLUTAMINE-329 BY ARGININE IN THE GAMMA-CHAIN THAT IMPAIRS THE POLYMERIZATION OF FIBRIN MONOMERJournal of Biochemistry. 1989 | Pubmed ID: Представляя ген нокаут непосредственно в Amastigote Этап trypanosoma cruzi Использование CRISPR / Cas9 системы Yukie Akutsu1, Motomichi Doi1, Koji Furukawa1, Yuko Takagi1 1Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST) JoVE 59962 Genetics
Представляя ген нокаут непосредственно в Amastigote Этап trypanosoma cruzi Использование CRISPR / Cas9 системы Yukie Akutsu1, Motomichi Doi1, Koji Furukawa1, Yuko Takagi1 1Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST) JoVE 59962 Genetics
