Korkut Uygun Biography Publications JoVE Articles Korkut Uygun has not added a biography. If you are Korkut Uygun and would like to personalize this page please email our Author Liaison for assistance. Publications The Autonomization Principle in Vascularized Flaps: An Alternative Strategy for Composite Tissue Scaffold In Vivo Revascularization Bioengineering (Basel, Switzerland). Dec, 2023 | Pubmed ID: 38136031 Towards Optimizing Sub-Normothermic Machine Perfusion in Fasciocutaneous Flaps: A Large Animal Study Bioengineering (Basel, Switzerland). Dec, 2023 | Pubmed ID: 38136006 Response Regarding: Continuous Versus Pulsatile Flow in 24-h Vascularized Composite Allograft Machine Perfusion in Swine: A Pilot Study The Journal of Surgical Research. Nov, 2023 | Pubmed ID: 37517972 Gluteal Propeller Perforator Flaps: A Paradigm Shift in Abdominoperineal Amputation Reconstruction Journal of Clinical Medicine. Jun, 2023 | Pubmed ID: 37373707 Continuous Versus Pulsatile Flow in 24-Hour Vascularized Composite Allograft Machine Perfusion in Swine: A Pilot Study The Journal of Surgical Research. Mar, 2023 | Pubmed ID: 36915006 Development of a Rat Forelimb Vascularized Composite Allograft (VCA) Perfusion Protocol PloS One. 2023 | Pubmed ID: 36652460 The Role of Antifreeze Glycoprotein (AFGP) and Polyvinyl Alcohol/polyglycerol (X/Z-1000) As Ice Modulators During Partial Freezing of Rat Livers Frontiers in Physics. 2022 | Pubmed ID: 37151819 Microvascular Assessment of Fascio-cutaneous Flaps by Ultrasound: A Large Animal Study Frontiers in Physiology. 2022 | Pubmed ID: 36589429 Subnormothermic Ex Vivo Porcine Kidney Perfusion Improves Energy Metabolism: Analysis Using P Magnetic Resonance Spectroscopic Imaging Transplantation Direct. Oct, 2022 | Pubmed ID: 36176724 Pan-caspase Inhibition During Normothermic Machine Perfusion of Discarded Livers Mitigates Innate Immune Responses Frontiers in Immunology. 2022 | Pubmed ID: 35958587 A Novel Digital Algorithm for Identifying Liver Steatosis Using Smartphone-Captured Images Transplantation Direct. Sep, 2022 | Pubmed ID: 35935028 Partial Freezing of Rat Livers Extends Preservation Time by 5-fold Nature Communications. Jul, 2022 | Pubmed ID: 35840553 Exceeding the Limits of Static Cold Storage in Limb Transplantation Using Subnormothermic Machine Perfusion Journal of Reconstructive Microsurgery. Oct, 2022 | Pubmed ID: 35764315 Modeling Energy Depletion in Rat Livers Using Nash Equilibrium Metabolic Pathway Analysis Scientific Reports. Mar, 2022 | Pubmed ID: 35241684 Specific Patterns of Vital Sign Fluctuations Predict Infection and Enable Sepsis Diagnosis in Pediatric Burn Patients PloS One. 2022 | Pubmed ID: 35130306 CYP450 Drug Inducibility in NAFLD Via an in Vitro Hepatic Model: Understanding Drug-drug Interactions in the Fatty Liver Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Feb, 2022 | Pubmed ID: 35062050 Activation of Autophagy During Normothermic Machine Perfusion of Discarded Livers is Associated with Improved Hepatocellular Function American Journal of Physiology. Gastrointestinal and Liver Physiology. Jan, 2022 | Pubmed ID: 34730028 Optimization of Ex Vivo Machine Perfusion and Transplantation of Vascularized Composite Allografts The Journal of Surgical Research. Feb, 2022 | Pubmed ID: 34670191 The Effect of Blood Cells Retained in Rat Livers During Static Cold Storage on Viability Outcomes During Normothermic Machine Perfusion Scientific Reports. Nov, 2021 | Pubmed ID: 34848781 Non-invasive Quantification of the Mitochondrial Redox State in Livers During Machine Perfusion PloS One. 2021 | Pubmed ID: 34705828 Thrombolytic Therapy During Normothermic Machine Perfusion of Human Livers Reduces Peribiliary Vascular Plexus Injury Frontiers in Surgery. 2021 | Pubmed ID: 34222314 In Vivo Activity of Genetically Modified Cells Preseeded in Rat Vascularized Composite Allografts Transplantation Proceedings. May, 2021 | Pubmed ID: 33985799 Liver Donor Age Affects Hepatocyte Function Through Age-dependent Changes in Decellularized Liver Matrix Biomaterials. Mar, 2021 | Pubmed ID: 33524812 Evolving Utilization of Donation After Circulatory Death Livers in Liver Transplantation: The Day of DCD Has Come Clinical Transplantation. Mar, 2021 | Pubmed ID: 33368701 A Portable Single-sided Magnetic-resonance Sensor for the Grading of Liver Steatosis and Fibrosis Nature Biomedical Engineering. Mar, 2021 | Pubmed ID: 33257853 Multiorgan Metabolomics and Lipidomics Provide New Insights Into Fat Infiltration in the Liver, Muscle Wasting, and Liver-Muscle Crosstalk Following Burn Injury Journal of Burn Care & Research : Official Publication of the American Burn Association. Mar, 2021 | Pubmed ID: 32877506 Twenty-four Hour Ex-vivo Normothermic Machine Perfusion in Rat Livers Technology. 2020 | Pubmed ID: 34307768 Viability Testing of Discarded Livers with Normothermic Machine Perfusion: Alleviating the Organ Shortage Outweighs the Cost Clinical Transplantation. Nov, 2020 | Pubmed ID: 32860634 Tryptophan Metabolism Via the Kynurenine Pathway: Implications for Graft Optimization During Machine Perfusion Journal of Clinical Medicine. Jun, 2020 | Pubmed ID: 32549246 Subzero Non-frozen Preservation of Human Livers in the Supercooled State Nature Protocols. Jun, 2020 | Pubmed ID: 32433625 Improvement of Steatotic Rat Liver Function with a Defatting Cocktail During Ex Situ Normothermic Machine Perfusion is Not Directly Related to Liver Fat Content PloS One. 2020 | Pubmed ID: 32396553 Cell Release During Perfusion Reflects Cold Ischemic Injury in Rat Livers Scientific Reports. Jan, 2020 | Pubmed ID: 31980677 Metabolic and Lipidomic Profiling of Steatotic Human Livers During Ex Situ normothermic Machine Perfusion Guides Resuscitation Strategies PloS One. 2020 | Pubmed ID: 31978172 Split-Liver Ex Situ Machine Perfusion: A Novel Technique for Studying Organ Preservation and Therapeutic Interventions Journal of Clinical Medicine. Jan, 2020 | Pubmed ID: 31963739 Pumping New Life into Old Ideas: Preservation and Rehabilitation of the Liver Using Ex Situ Machine Perfusion Artificial Organs. Feb, 2020 | Pubmed ID: 31691326 The Efficacy of HBOC-201 in Ex Situ Gradual Rewarming Kidney Perfusion in a Rat Model Artificial Organs. Jan, 2020 | Pubmed ID: 31368159 Ex Vivo Perfusion-based Engraftment of Genetically Engineered Cell Sensors into Transplantable Organs PloS One. 2019 | Pubmed ID: 31790444 Subnormothermic Machine Perfusion of Steatotic Livers Results in Increased Energy Charge at the Cost of Anti-Oxidant Capacity Compared to Normothermic Perfusion Metabolites. Oct, 2019 | Pubmed ID: 31652927 Supercooling Extends Preservation Time of Human Livers Nature Biotechnology. Oct, 2019 | Pubmed ID: 31501557 Leveraging the Zebrafish to Model Organ Transplantation Current Opinion in Organ Transplantation. Oct, 2019 | Pubmed ID: 31483338 Exploring Donor Demographics Effects on Hepatocyte Yield and Viability: Results of Whole Human Liver Isolation from One Center Technology. 2019 | Pubmed ID: 31414037 Systems Engineering the Organ Preservation Process for Transplantation Current Opinion in Biotechnology. Aug, 2019 | Pubmed ID: 31280087 Synthetic Hemoglobin-based Oxygen Carriers Are an Acceptable Alternative for Packed Red Blood Cells in Normothermic Kidney Perfusion American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Oct, 2019 | Pubmed ID: 30938927 Increasing Donor Liver Utilization Through Machine Perfusion Hepatology (Baltimore, Md.). Jul, 2019 | Pubmed ID: 30681724 Specific Patterns of Postoperative Temperature Elevations Predict Blood Infection in Pediatric Burn Patients Journal of Burn Care & Research : Official Publication of the American Burn Association. Feb, 2019 | Pubmed ID: 30668737 Bulk Droplet Vitrification: An Approach to Improve Large-Scale Hepatocyte Cryopreservation Outcome Langmuir : the ACS Journal of Surfaces and Colloids. Jun, 2019 | Pubmed ID: 30514081 Oxygenated UW Solution Decreases ATP Decay and Improves Survival After Transplantation of DCD Liver Grafts Transplantation. Feb, 2019 | Pubmed ID: 30422952 Effect of Ice Nucleation and Cryoprotectants During High Subzero-Preservation in Endothelialized Microchannels ACS Biomaterials Science & Engineering. Aug, 2018 | Pubmed ID: 31544149 Post-hepatectomy Liver Regeneration in the Context of Bile Acid Homeostasis and the Gut-liver Signaling Axis Journal of Clinical and Translational Research. May, 2018 | Pubmed ID: 30761355 Contrast-Enhanced Ultrasound to Quantifyc Perfusion in a Machine-Perfused Pig Liver Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. Jul, 2018 | Pubmed ID: 30441057 Advances in Machine Perfusion, Organ Preservation, and Cryobiology: Potential Impact on Vascularized Composite Allotransplantation Current Opinion in Organ Transplantation. Oct, 2018 | Pubmed ID: 30080697 Endothelial Dysfunction in Steatotic Human Donor Livers: A Pilot Study of the Underlying Mechanism During Subnormothermic Machine Perfusion Transplantation Direct. May, 2018 | Pubmed ID: 29796416 Caspase Inhibition: Optimizing Grafts for Transplantation Transplantation. Sep, 2018 | Pubmed ID: 29757905 Improved Cuff Technique and Intraoperative Detection of Vascular Complications for Hind Limb Transplantation in Mice Transplantation Direct. Feb, 2018 | Pubmed ID: 29464206 A Novel Model for Ex Situ Reperfusion of the Human Liver Following Subnormothermic Machine Perfusion Technology. Dec, 2017 | Pubmed ID: 31106253 Multi-omic Network-based Interrogation of Rat Liver Metabolism Following Gastric Bypass Surgery Featuring SWATH Proteomics Technology. Sep, 2017 | Pubmed ID: 29780857 Metabolomic Modularity Analysis (MMA) to Quantify Human Liver Perfusion Dynamics Metabolites. Nov, 2017 | Pubmed ID: 29137180 A Highly-occupied, Single-cell Trapping Microarray for Determination of Cell Membrane Permeability Lab on a Chip. 11, 2017 | Pubmed ID: 29068447 The Promise of Organ and Tissue Preservation to Transform Medicine Nature Biotechnology. 06, 2017 | Pubmed ID: 28591112 Subzero Organ Preservation: the Dawn of a New Ice Age? Current Opinion in Organ Transplantation. Jun, 2017 | Pubmed ID: 28266941 Liver Ex Situ Machine Perfusion Preservation: A Review of the Methodology and Results of Large Animal Studies and Clinical Trials Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. May, 2017 | Pubmed ID: 28240817 Peritransplant Energy Changes and Their Correlation to Outcome After Human Liver Transplantation Transplantation. Jul, 2017 | Pubmed ID: 28230641 Nuclear Receptors Control Pro-viral and Antiviral Metabolic Responses to Hepatitis C Virus Infection Nature Chemical Biology. Dec, 2016 | Pubmed ID: 27723751 Metabolic Profiling During Ex Vivo Machine Perfusion of the Human Liver Scientific Reports. Mar, 2016 | Pubmed ID: 26935866 Machine Perfusion Enhances Hepatocyte Isolation Yields from Ischemic Livers Cryobiology. Oct, 2015 | Pubmed ID: 26188080 Warm Ischemic Injury Is Reflected in the Release of Injury Markers During Cold Preservation of the Human Liver PloS One. 2015 | Pubmed ID: 25822248 Surgical Models of Roux-en-Y Gastric Bypass Surgery and Sleeve Gastrectomy in Rats and Mice Nature Protocols. Mar, 2015 | Pubmed ID: 25719268 Supercooling Preservation and Transplantation of the Rat Liver Nature Protocols. Mar, 2015 | Pubmed ID: 25692985 Organomatics and Organometrics: Novel Platforms for Long-term Whole-organ Culture Technology. Mar, 2014 | Pubmed ID: 25035864 Supercooling Enables Long-term Transplantation Survival Following 4 Days of Liver Preservation Nature Medicine. Jul, 2014 | Pubmed ID: 24973919 Injury to Peribiliary Glands and Vascular Plexus Before Liver Transplantation Predicts Formation of Non-anastomotic Biliary Strictures Journal of Hepatology. Jun, 2014 | Pubmed ID: 24560661 SIMPLE MACHINE PERFUSION SIGNIFICANTLY ENHANCES HEPATOCYTE YIELDS OF ISCHEMIC AND FRESH RAT LIVERS Cell Medicine. 2013 | Pubmed ID: 25431743 Determination and Extension of the Limits to Static Cold Storage Using Subnormothermic Machine Perfusion The International Journal of Artificial Organs. Nov, 2013 | Pubmed ID: 24338652 Perfusion Defatting at Subnormothermic Temperatures in Steatotic Rat Livers Transplantation Proceedings. Nov, 2013 | Pubmed ID: 24182786 Resuscitation of Ischemic Donor Livers with Normothermic Machine Perfusion: a Metabolic Flux Analysis of Treatment in Rats PloS One. 2013 | Pubmed ID: 23922793 Strategies to Rescue Steatotic Livers Before Transplantation in Clinical and Experimental Studies World Journal of Gastroenterology : WJG. Aug, 2013 | Pubmed ID: 23922462 Supercooling As a Viable Non-freezing Cell Preservation Method of Rat Hepatocytes PloS One. 2013 | Pubmed ID: 23874947 Development of Metabolic Indicators of Burn Injury: Very Low Density Lipoprotein (VLDL) and Acetoacetate Are Highly Correlated to Severity of Burn Injury in Rats Metabolites. 2012 | Pubmed ID: 24957642 A Simplified Subnormothermic Machine Perfusion System Restores Ischemically Damaged Liver Grafts in a Rat Model of Orthotopic Liver Transplantation Transplantation Research. 2012 | Pubmed ID: 23369351 Application of Whole-organ Tissue Engineering in Hepatology Nature Reviews. Gastroenterology & Hepatology. Dec, 2012 | Pubmed ID: 22890112 A Fitness Index for Transplantation of Machine-perfused Cadaveric Rat Livers BMC Research Notes. 2012 | Pubmed ID: 22731806 Una Novela De Hígado En 3D Sistema De Organoides Para El Esclarecimiento Del Metabolismo De Glucosa Hepática Biotechnology and Bioengineering. Feb, 2012 | Pubmed ID: 22006574 Un índice Metabólico De La Lesión Isquémica De La Perfusión De Recuperación De Los Hígados De Rata Cadavéricos PloS One. 2011 | Pubmed ID: 22194843 Máquina De Perfusión Subnormothermic En Ambos De 20 ° C Y 30 ° C Recupera Los Hígados De Ratas Isquémicas Para El éxito Del Trasplante The Journal of Surgical Research. Mar, 2011 | Pubmed ID: 21550058 De Todo El órgano De Ingeniería De Tejidos: Descelularización Y Recelularización De Andamios Matriz Tridimensional Annual Review of Biomedical Engineering. Aug, 2011 | Pubmed ID: 21417722 In Situ Análisis De Flujo Metabólico Para Cuantificar La Respuesta Metabólica Del Hígado De Lesiones Por Quemaduras Experimental Biotechnology and Bioengineering. Apr, 2011 | Pubmed ID: 21404258 In Situ Análisis De Flujo Metabólico Para Cuantificar La Respuesta Metabólica Del Hígado De Lesiones Por Quemaduras Experimental Biotechnology and Bioengineering. Nov, 2010 | Pubmed ID: 21077107 Optimización Basada En Análisis De Control Metabólico Biotechnology Progress. Nov-Dec, 2010 | Pubmed ID: 20967921 Diluted Blood Reperfusion As a Model for Transplantation of Ischemic Rat Livers: Alanine Aminotransferase is a Direct Indicator of Viability Transplantation Proceedings. Sep, 2010 | Pubmed ID: 20832525 Reingeniería De órganos a Través Del Desarrollo De Un Injerto Hepático Trasplantables Recelularizado Usando La Matriz Descelularizado Hígado Nature Medicine. Jul, 2010 | Pubmed ID: 20543851 Entrega De La Célula: Desde El Trasplante De Células a La Ingeniería De órganos Cell Transplantation. 2010 | Pubmed ID: 20525441 Efectos De Las Lesiones Por Quemaduras En Los Marcadores De Hipermetabolismo En Ratas Journal of Burn Care & Research : Official Publication of the American Burn Association. Nov-Dec, 2009 | Pubmed ID: 19898103 De Alto Rendimiento De Células Matrices Single Como Una Herramienta Novedosa En La Bioconservación Cryobiology. Jun, 2009 | Pubmed ID: 19303403 La Recuperación De Warm Injertos De Hígado De Rata Por Isquémicos La Perfusión Extracorpórea Normotérmica Transplantation. Jan, 2009 | Pubmed ID: 19155970 Modelos De Crecimiento De Tejido En Un Biorreactor Ondulado De Pared Tissue Engineering. Part A. Apr, 2009 | Pubmed ID: 18847355 Sequential Cold Storage and Normothermic Perfusion of the Ischemic Rat Liver Transplantation Proceedings. Jun, 2008 | Pubmed ID: 18589093 Un Modelo Para La Preservación De La Normotérmica Hígado De Rata Tissue Engineering. Aug, 2007 | Pubmed ID: 17596120 Investigación De Los Objetivos Metabólicos En Hepatocitos Cultivados Biotechnology and Bioengineering. Jun, 2007 | Pubmed ID: 17058287 A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds JoVE 66362 Medicine Author Spotlight: Context Dependent Blood Collection Methods in Rats Laura Charlès1,2,3, Thomas Agius*4,5, Irina Filz von Reiterdank*1,2,3,6, Janna Hagedorn1,2,3, Yanis Berkane1,2,3,7, Hyshem H. Lancia1,2,3, Basak E. Uygun2,3,8, Korkut Uygun2,3,8, Curtis L. Cetrulo Jr.1,2,3,9, Mark A. Randolph1,2,3,9, Alexandre G. Lellouch1,2,3,8 1Vascularized Composite Allotransplantation Laboratory, Massachusetts General Hospital, 2Harvard Medical School, 3Shriners Children’s Boston, 4Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, 5Department of Vascular Surgery, Centre Hospitalier Universitaire Vaudois and University of Lausanne, 6Department of Plastic, Reconstructive and Hand Surgery, University Medical Center Utrecht, 7Department of Plastic, Reconstructive and Aesthetic Surgery, Rennes University Hospital Center (CHU de Rennes), Rennes 1 University, 8Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, 9Plastic Surgery Research Laboratory, Massachusetts General Hospital JoVE 65513 Medicine El colgajo axial superficial de la arteria epigástrica inferior para estudiar los efectos del preacondicionamiento isquémico en un modelo de rata Yanis Berkane*1,2,3,5, Austin Alana Shamlou*1,2,4,5, Jose Reyes1,2, Hyshem H. Lancia1,2,5, Irina Filz von Reiterdank1,2,5,6,7, Nicolas Bertheuil3, Basak E. Uygun2,5,6, Korkut Uygun1,2,5,6, William G. Austen Jr.2,4, Curtis L. Cetrulo Jr.1,2,4,5, Mark A. Randolph1,2,4,5, Alexandre G. Lellouch1,2,5,6,8 1Vascularized Composite Allotransplantation Laboratory, Massachusetts General Hospital, 2Harvard Medical School, 3Department of Plastic, Reconstructive and Aesthetic Surgery, Rennes University Hospital Center (CHU de Rennes), University of Rennes 1, 4Plastic Surgery Research Laboratory, Massachusetts General Hospital, 5Shriners Children's Boston, 6Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, 7Department of Plastic Surgery and Hand Surgery, University Medical Center Utrecht, 8Department of Plastic, Reconstructive, and Aesthetic Surgery, Groupe Almaviva Santé, Clinique de l'Alma JoVE 64980 Immunology and Infection Modelo de trasplante parcial de extremidades posteriores heterotópicas en ratas Marion Goutard1,2,3, Mark A. Randolph1,2,3, Corentin B. Taveau1,2,3,4, Elise Lupon1,2,3, Laurent Lantieri4, Korkut Uygun1,2,3, Curtis L. Cetrulo Jr.*1,2,3, Alexandre G. Lellouch*1,2,3,4 1Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Harvard Medical School, 2Vascularized Composite Allotransplantation Laboratory, Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, 3Shriners Hospital for Children, 4Service de Chirurgie Plastique, Hôpital Européen Georges Pompidou, Assistance Publique-Hôpitaux de Paris (APHP), Université de Paris JoVE 62586 Immunology and Infection Vitrificación de gotas a granel para la preservación de hepatocitos primarios Reinier J. de Vries1,2,3, Peony D. Banik1,2, Sonal Nagpal1,2, Lindong Weng1,2, Sinan Ozer1,2, Thomas M. van Gulik3, Mehmet Toner1,2, Shannon N. Tessier1,2, Korkut Uygun1,2 1Center for Engineering in Medicine, Harvard Medical School, Massachusetts General Hospital, 2Shriners Hospitals for Children, Boston, 3Department of Surgery, University of Amsterdam JoVE 60250 Bioengineering Ex Situ Normotérmica máquina de perfusión de hígados de donantes Negin Karimian1,2, Alix P.M. Matton1,2, Andrie C. Westerkamp1,2, Laura C. Burlage1,2, Sanna op den Dries1,2, Henri G.D. Leuvenink2, Ton Lisman1,2, Korkut Uygun3, James F. Markmann4, Robert J. Porte1,2 1Section of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, University of Groningen, University Medical Center Groningen, 2Surgical Research Laboratory, Department of Surgery, University of Groningen, University Medical Center Groningen, 3Center of Engineering in Medicine/Surgical Services, Massachusetts General Hospital, Harvard Medical School, and Shriners Burns Hospital, 4Division of Transplantation, Department of Surgery, Massachusetts General Hospital, Harvard Medical School JoVE 52688 Medicine Funcional hígado humano Conservación y Recuperación de Medios de Subnormothermic máquina de perfusión Bote G. Bruinsma*1, James H. Avruch*2, Pepijn D. Weeder1, Gautham V. Sridharan1, Basak E. Uygun1, Negin G. Karimian1, Robert J. Porte3, James F. Markmann2, Heidi Yeh2, Korkut Uygun1 1Center for Engineering in Medicine, Dept. of Surgery, Massachusetts General Hospital, Harvard Medical School, 2Transplant Center, Dept. of Surgery, Massachusetts General Hospital, Harvard Medical School, 3Section of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, University Medical Center Groningen, University of Groningen JoVE 52777 Medicine Descelularización y recelularización de hígados enteros Basak E. Uygun1, Gavrielle Price1, Nima Saeidi1, Maria-Louisa Izamis1, Tim Berendsen1, Martin Yarmush1, Korkut Uygun1 1Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Shriners Hospitals for Children JoVE 2394 Bioengineering
A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds JoVE 66362 Medicine
Author Spotlight: Context Dependent Blood Collection Methods in Rats Laura Charlès1,2,3, Thomas Agius*4,5, Irina Filz von Reiterdank*1,2,3,6, Janna Hagedorn1,2,3, Yanis Berkane1,2,3,7, Hyshem H. Lancia1,2,3, Basak E. Uygun2,3,8, Korkut Uygun2,3,8, Curtis L. Cetrulo Jr.1,2,3,9, Mark A. Randolph1,2,3,9, Alexandre G. Lellouch1,2,3,8 1Vascularized Composite Allotransplantation Laboratory, Massachusetts General Hospital, 2Harvard Medical School, 3Shriners Children’s Boston, 4Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, 5Department of Vascular Surgery, Centre Hospitalier Universitaire Vaudois and University of Lausanne, 6Department of Plastic, Reconstructive and Hand Surgery, University Medical Center Utrecht, 7Department of Plastic, Reconstructive and Aesthetic Surgery, Rennes University Hospital Center (CHU de Rennes), Rennes 1 University, 8Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, 9Plastic Surgery Research Laboratory, Massachusetts General Hospital JoVE 65513 Medicine
El colgajo axial superficial de la arteria epigástrica inferior para estudiar los efectos del preacondicionamiento isquémico en un modelo de rata Yanis Berkane*1,2,3,5, Austin Alana Shamlou*1,2,4,5, Jose Reyes1,2, Hyshem H. Lancia1,2,5, Irina Filz von Reiterdank1,2,5,6,7, Nicolas Bertheuil3, Basak E. Uygun2,5,6, Korkut Uygun1,2,5,6, William G. Austen Jr.2,4, Curtis L. Cetrulo Jr.1,2,4,5, Mark A. Randolph1,2,4,5, Alexandre G. Lellouch1,2,5,6,8 1Vascularized Composite Allotransplantation Laboratory, Massachusetts General Hospital, 2Harvard Medical School, 3Department of Plastic, Reconstructive and Aesthetic Surgery, Rennes University Hospital Center (CHU de Rennes), University of Rennes 1, 4Plastic Surgery Research Laboratory, Massachusetts General Hospital, 5Shriners Children's Boston, 6Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, 7Department of Plastic Surgery and Hand Surgery, University Medical Center Utrecht, 8Department of Plastic, Reconstructive, and Aesthetic Surgery, Groupe Almaviva Santé, Clinique de l'Alma JoVE 64980 Immunology and Infection
Modelo de trasplante parcial de extremidades posteriores heterotópicas en ratas Marion Goutard1,2,3, Mark A. Randolph1,2,3, Corentin B. Taveau1,2,3,4, Elise Lupon1,2,3, Laurent Lantieri4, Korkut Uygun1,2,3, Curtis L. Cetrulo Jr.*1,2,3, Alexandre G. Lellouch*1,2,3,4 1Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Harvard Medical School, 2Vascularized Composite Allotransplantation Laboratory, Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, 3Shriners Hospital for Children, 4Service de Chirurgie Plastique, Hôpital Européen Georges Pompidou, Assistance Publique-Hôpitaux de Paris (APHP), Université de Paris JoVE 62586 Immunology and Infection
Vitrificación de gotas a granel para la preservación de hepatocitos primarios Reinier J. de Vries1,2,3, Peony D. Banik1,2, Sonal Nagpal1,2, Lindong Weng1,2, Sinan Ozer1,2, Thomas M. van Gulik3, Mehmet Toner1,2, Shannon N. Tessier1,2, Korkut Uygun1,2 1Center for Engineering in Medicine, Harvard Medical School, Massachusetts General Hospital, 2Shriners Hospitals for Children, Boston, 3Department of Surgery, University of Amsterdam JoVE 60250 Bioengineering
Ex Situ Normotérmica máquina de perfusión de hígados de donantes Negin Karimian1,2, Alix P.M. Matton1,2, Andrie C. Westerkamp1,2, Laura C. Burlage1,2, Sanna op den Dries1,2, Henri G.D. Leuvenink2, Ton Lisman1,2, Korkut Uygun3, James F. Markmann4, Robert J. Porte1,2 1Section of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, University of Groningen, University Medical Center Groningen, 2Surgical Research Laboratory, Department of Surgery, University of Groningen, University Medical Center Groningen, 3Center of Engineering in Medicine/Surgical Services, Massachusetts General Hospital, Harvard Medical School, and Shriners Burns Hospital, 4Division of Transplantation, Department of Surgery, Massachusetts General Hospital, Harvard Medical School JoVE 52688 Medicine
Funcional hígado humano Conservación y Recuperación de Medios de Subnormothermic máquina de perfusión Bote G. Bruinsma*1, James H. Avruch*2, Pepijn D. Weeder1, Gautham V. Sridharan1, Basak E. Uygun1, Negin G. Karimian1, Robert J. Porte3, James F. Markmann2, Heidi Yeh2, Korkut Uygun1 1Center for Engineering in Medicine, Dept. of Surgery, Massachusetts General Hospital, Harvard Medical School, 2Transplant Center, Dept. of Surgery, Massachusetts General Hospital, Harvard Medical School, 3Section of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, University Medical Center Groningen, University of Groningen JoVE 52777 Medicine
Descelularización y recelularización de hígados enteros Basak E. Uygun1, Gavrielle Price1, Nima Saeidi1, Maria-Louisa Izamis1, Tim Berendsen1, Martin Yarmush1, Korkut Uygun1 1Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Shriners Hospitals for Children JoVE 2394 Bioengineering