Kostas Kostarelos

Publications

• Functionalized Carbon Nanotubes in the Brain: Cellular Internalization and Neuroinflammatory Responses
  PloS One. 2013  |   Pubmed ID: 24260521
• Carbon Nanotubes in Medicine & Biology - Therapy and Diagnostics
  Advanced Drug Delivery Reviews. Dec, 2013  |   Pubmed ID: 24220279
• Hemotoxicity of Carbon Nanotubes
  Advanced Drug Delivery Reviews. Dec, 2013  |   Pubmed ID: 24211768
• Carbon Nanotubes in Medicine and Biology - Safety and Toxicology
  Advanced Drug Delivery Reviews. Dec, 2013  |   Pubmed ID: 24211669
• Carbon Nanotubes As Vectors for Gene Therapy: Past Achievements, Present Challenges and Future Goals
  Advanced Drug Delivery Reviews. Dec, 2013  |   Pubmed ID: 24184373
• Pharmacology of Carbon Nanotubes: Toxicokinetics, Excretion and Tissue Accumulation
  Advanced Drug Delivery Reviews. Dec, 2013  |   Pubmed ID: 24184372
• How Do Functionalized Carbon Nanotubes Land On, Bind to and Pierce Through Model and Plasma Membranes
  Nanoscale. Nov, 2013  |   Pubmed ID: 24056765
• Ammonium and Guanidinium Dendron-Carbon Nanotubes by Amidation and Click Chemistry and Their Use for SiRNA Delivery
  Small (Weinheim an Der Bergstrasse, Germany). May, 2013  |   Pubmed ID: 23650276
• Pulmonary DWCNT Exposure Causes Sustained Local and Low-level Systemic Inflammatory Changes in Mice
  European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. Mar, 2013  |   Pubmed ID: 23542608
• Cationic Poly-L-lysine Dendrimer Complexes Doxorubicin and Delays Tumor Growth in Vitro and in Vivo
  ACS Nano. Mar, 2013  |   Pubmed ID: 23527750
• Prospects and Challenges of Graphene in Biomedical Applications
  Advanced Materials (Deerfield Beach, Fla.). Apr, 2013  |   Pubmed ID: 23494834
• Autophagy and Formation of Tubulovesicular Autophagosomes Provide a Barrier Against Nonviral Gene Delivery
  Autophagy. May, 2013  |   Pubmed ID: 23422759
• The Effective Nuclear Delivery of Doxorubicin from Dextran-coated Gold Nanoparticles Larger Than Nuclear Pores
  Biomaterials. Apr, 2013  |   Pubmed ID: 23395274
• In Vivo Cell Reprogramming Towards Pluripotency by Virus-free Overexpression of Defined Factors
  PloS One. 2013  |   Pubmed ID: 23355895
• Asbestos-like Pathogenicity of Long Carbon Nanotubes Alleviated by Chemical Functionalization
  Angewandte Chemie (International Ed. in English). Feb, 2013  |   Pubmed ID: 23319294
• Electroresponsive Polymer-carbon Nanotube Hydrogel Hybrids for Pulsatile Drug Delivery in Vivo
  Advanced Healthcare Materials. Jun, 2013  |   Pubmed ID: 23184678
• Purified Graphene Oxide Dispersions Lack in Vitro Cytotoxicity and in Vivo Pathogenicity
  Advanced Healthcare Materials. Mar, 2013  |   Pubmed ID: 23184580
• Safety Considerations for Graphene: Lessons Learnt from Carbon Nanotubes
  Accounts of Chemical Research. Mar, 2013  |   Pubmed ID: 23163827
• The Effect of Artificial Lipid Envelopment of Adenovirus 5 (Ad5) on Liver De-targeting and Hepatotoxicity
  Biomaterials. Jan, 2013  |   Pubmed ID: 23146432
• A High Poly(ethylene Glycol) Density on Graphene Nanomaterials Reduces the Detachment of Lipid-poly(ethylene Glycol) and Macrophage Uptake
  Acta Biomaterialia. Jan, 2013  |   Pubmed ID: 22995407
• Lipid-peptide Vesicle Nanoscale Hybrids for Triggered Drug Release by Mild Hyperthermia in Vitro and in Vivo
  ACS Nano. Oct, 2012  |   Pubmed ID: 22857653
• Liposome-gold Nanorod Hybrids for High-resolution Visualization Deep in Tissues
  Journal of the American Chemical Society. Aug, 2012  |   Pubmed ID: 22852749
• In Vivo Degradation of Functionalized Carbon Nanotubes After Stereotactic Administration in the Brain Cortex
  Nanomedicine (London, England). Oct, 2012  |   Pubmed ID: 22712575
• Degree of Chemical Functionalization of Carbon Nanotubes Determines Tissue Distribution and Excretion Profile
  Angewandte Chemie (International Ed. in English). Jun, 2012  |   Pubmed ID: 22623333
• Application of Carbon Nanotubes in Neurology: Clinical Perspectives and Toxicological Risks
  Archives of Toxicology. Jul, 2012  |   Pubmed ID: 22547313
• Therapeutics, Imaging and Toxicity of Nanomaterials in the Central Nervous System
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Jul, 2012  |   Pubmed ID: 22512901
• Pharmacokinetics & Tissue Distribution of Temperature-sensitive Liposomal Doxorubicin in Tumor-bearing Mice Triggered with Mild Hyperthermia
  Biomaterials. Jun, 2012  |   Pubmed ID: 22459195
• Targeting Carbon Nanotubes Against Cancer
  Chemical Communications (Cambridge, England). Apr, 2012  |   Pubmed ID: 22428156
• Translocation Mechanisms of Chemically Functionalised Carbon Nanotubes Across Plasma Membranes
  Biomaterials. Apr, 2012  |   Pubmed ID: 22289266
• Carbon Nanotube-mediated Wireless Cell Permeabilization: Drug and Gene Uptake
  Nanomedicine (London, England). Dec, 2011  |   Pubmed ID: 22122583
• Diameter and Rigidity of Multiwalled Carbon Nanotubes Are Critical Factors in Mesothelial Injury and Carcinogenesis
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011  |   Pubmed ID: 22084097
• Cellular Uptake and Cytotoxic Impact of Chemically Functionalized and Polymer-coated Carbon Nanotubes
  Small (Weinheim an Der Bergstrasse, Germany). Nov, 2011  |   Pubmed ID: 21919194
• Liposomes: from a Clinically Established Drug Delivery System to a Nanoparticle Platform for Theranostic Nanomedicine
  Accounts of Chemical Research. Oct, 2011  |   Pubmed ID: 21812415
• Making Carbon Nanotubes Biocompatible and Biodegradable
  Chemical Communications (Cambridge, England). Oct, 2011  |   Pubmed ID: 21776531
• Functional Motor Recovery from Brain Ischemic Insult by Carbon Nanotube-mediated SiRNA Silencing
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2011  |   Pubmed ID: 21690348
• Length-dependent Retention of Carbon Nanotubes in the Pleural Space of Mice Initiates Sustained Inflammation and Progressive Fibrosis on the Parietal Pleura
  The American Journal of Pathology. Jun, 2011  |   Pubmed ID: 21641383
• Antibody Covalent Immobilization on Carbon Nanotubes and Assessment of Antigen Binding
  Small (Weinheim an Der Bergstrasse, Germany). Aug, 2011  |   Pubmed ID: 21608125
• Cellular Uptake Mechanisms of Functionalised Multi-walled Carbon Nanotubes by 3D Electron Tomography Imaging
  Nanoscale. Jun, 2011  |   Pubmed ID: 21603701
• Cytotoxic Assessment of Carbon Nanotube Interaction with Cell Cultures
  Methods in Molecular Biology (Clifton, N.J.). 2011  |   Pubmed ID: 21424457
• Doxorubicin-loaded Lipid-quantum Dot Hybrids: Surface Topography and Release Properties
  International Journal of Pharmaceutics. Sep, 2011  |   Pubmed ID: 21315141
• Intracellular Trafficking and Gene Expression of PH-sensitive, Artificially Enveloped Adenoviruses in Vitro and in Vivo
  Biomaterials. Apr, 2011  |   Pubmed ID: 21269689
• The Alluring Potential of Functionalized Carbon Nanotubes in Drug Discovery
  Expert Opinion on Drug Discovery. Jul, 2010  |   Pubmed ID: 22823208
• Physiologically Based Pharmacokinetic Modeling of Nanoparticles
  ACS Nano. Nov, 2010  |   Pubmed ID: 20945925
• Hybrid Polymer-grafted Multiwalled Carbon Nanotubes for in Vitro Gene Delivery
  Small (Weinheim an Der Bergstrasse, Germany). Oct, 2010  |   Pubmed ID: 20878655
• Carbon Nanotubes: Fibrillar Pharmacology
  Nature Materials. Oct, 2010  |   Pubmed ID: 20864939
• Efficient Receptor-independent Intracellular Translocation of Aptamers Mediated by Conjugation to Carbon Nanotubes
  Chemical Communications (Cambridge, England). Oct, 2010  |   Pubmed ID: 20830345
• Filled and Glycosylated Carbon Nanotubes for in Vivo Radioemitter Localization and Imaging
  Nature Materials. Jun, 2010  |   Pubmed ID: 20473287
• Assessment of Cellular Uptake and Cytotoxicity of Carbon Nanotubes Using Flow Cytometry
  Methods in Molecular Biology (Clifton, N.J.). 2010  |   Pubmed ID: 20422386
• Nanorobots for Medicine: How Close Are We?
  Nanomedicine (London, England). Apr, 2010  |   Pubmed ID: 20394527
• Functionalized Carbon Nanotubes for Probing and Modulating Molecular Functions
  Chemistry & Biology. Feb, 2010  |   Pubmed ID: 20189101
• Enhanced Anticancer Activity of Multi-walled Carbon Nanotube-methotrexate Conjugates Using Cleavable Linkers
  Chemical Communications (Cambridge, England). Mar, 2010  |   Pubmed ID: 20162159
• Systemic Antiangiogenic Activity of Cationic Poly-L-lysine Dendrimer Delays Tumor Growth
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010  |   Pubmed ID: 20150514
• Nanoparticles Functionalized with Recombinant Single Chain Fv Antibody Fragments (scFv) for the Magnetic Resonance Imaging of Cancer Cells
  Biomaterials. Feb, 2010  |   Pubmed ID: 19889453
• Chapter 17 - Engineering Cationic Liposome SiRNA Complexes for in Vitro and in Vivo Delivery
  Methods in Enzymology. 2009  |   Pubmed ID: 19903563
• Tumor Targeting of Functionalized Quantum Dot-liposome Hybrids by Intravenous Administration
  Molecular Pharmaceutics. Mar-Apr, 2009  |   Pubmed ID: 19718803
• Blood Circulation and Tissue Biodistribution of Lipid--quantum Dot (L-QD) Hybrid Vesicles Intravenously Administered in Mice
  Bioconjugate Chemistry. Sep, 2009  |   Pubmed ID: 19655725
• Synthesis and Characterization of a Carbon Nanotube-dendron Series for Efficient SiRNA Delivery
  Journal of the American Chemical Society. Jul, 2009  |   Pubmed ID: 19555104
• Antitumor Activity and Prolonged Survival by Carbon-nanotube-mediated Therapeutic SiRNA Silencing in a Human Lung Xenograft Model
  Small (Weinheim an Der Bergstrasse, Germany). May, 2009  |   Pubmed ID: 19306454
• Designer Adenoviruses for Nanomedicine and Nanodiagnostics
  Trends in Biotechnology. Apr, 2009  |   Pubmed ID: 19251331
• Synthesis and Analysis of Novel Glycerolipids for the Treatment of Metabolic Syndrome
  Journal of Medicinal Chemistry. Feb, 2009  |   Pubmed ID: 19175322
• Lipid-quantum Dot Bilayer Vesicles Enhance Tumor Cell Uptake and Retention in Vitro and in Vivo
  ACS Nano. Mar, 2008  |   Pubmed ID: 19206564
• Nanoengineering Artificial Lipid Envelopes Around Adenovirus by Self-assembly
  ACS Nano. May, 2008  |   Pubmed ID: 19206502
• Functionalized-quantum-dot-liposome Hybrids As Multimodal Nanoparticles for Cancer
  Small (Weinheim an Der Bergstrasse, Germany). Sep, 2008  |   Pubmed ID: 18711753
• Carbon-nanotube Shape and Individualization Critical for Renal Excretion
  Small (Weinheim an Der Bergstrasse, Germany). Aug, 2008  |   Pubmed ID: 18666166
• The Long and Short of Carbon Nanotube Toxicity
  Nature Biotechnology. Jul, 2008  |   Pubmed ID: 18612299
• Artificial Envelopment of Nonenveloped Viruses: Enhancing Adenovirus Tumor Targeting in Vivo
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2008  |   Pubmed ID: 18556649
• Hype Around Nanotubes Creates Unrealistic Hopes
  Nature. May, 2008  |   Pubmed ID: 18480788
• Tissue Histology and Physiology Following Intravenous Administration of Different Types of Functionalized Multiwalled Carbon Nanotubes
  Nanomedicine (London, England). Apr, 2008  |   Pubmed ID: 18373422
• Opportunities and Challenges of Carbon-based Nanomaterials for Cancer Therapy
  Expert Opinion on Drug Delivery. Mar, 2008  |   Pubmed ID: 18318654
• Multiwalled Carbon Nanotube-doxorubicin Supramolecular Complexes for Cancer Therapeutics
  Chemical Communications (Cambridge, England). Jan, 2008  |   Pubmed ID: 18188467
• Functionalized Carbon Nanotubes in Drug Design and Discovery
  Accounts of Chemical Research. Jan, 2008  |   Pubmed ID: 17867649
• Cellular Uptake of Functionalized Carbon Nanotubes is Independent of Functional Group and Cell Type
  Nature Nanotechnology. Feb, 2007  |   Pubmed ID: 18654229
• Multifunctionalised Cationic Fullerene Adducts for Gene Transfer: Design, Synthesis and DNA Complexation
  Chemical Communications (Cambridge, England). Sep, 2007  |   Pubmed ID: 17851620
• Liposome-nanoparticle Hybrids for Multimodal Diagnostic and Therapeutic Applications
  Nanomedicine (London, England). Feb, 2007  |   Pubmed ID: 17716195
• Single-cell Dosimetry for Radioimmunotherapy of B-cell Lymphoma Patients with Special Reference to Leukemic Spread
  Cancer Biotherapy & Radiopharmaceuticals. Jun, 2007  |   Pubmed ID: 17651041
• Construction of Nanoscale Multicompartment Liposomes for Combinatory Drug Delivery
  International Journal of Pharmaceutics. Mar, 2007  |   Pubmed ID: 17223294
• The Emergence of Nanomedicine: a Field in the Making
  Nanomedicine (London, England). Jun, 2006  |   Pubmed ID: 17716200
• Establishing Nanomedicine
  Nanomedicine (London, England). Oct, 2006  |   Pubmed ID: 17716156
• Carbon Nanotubes As Nanomedicines: from Toxicology to Pharmacology
  Advanced Drug Delivery Reviews. Dec, 2006  |   Pubmed ID: 17113677
• Double Functionalization of Carbon Nanotubes for Multimodal Drug Delivery
  Chemical Communications (Cambridge, England). Mar, 2006  |   Pubmed ID: 16518484
• Tissue Biodistribution and Blood Clearance Rates of Intravenously Administered Carbon Nanotube Radiotracers
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2006  |   Pubmed ID: 16492781
• Functionalized Carbon Nanotubes As Emerging Nanovectors for the Delivery of Therapeutics
  Biochimica Et Biophysica Acta. Mar, 2006  |   Pubmed ID: 16307724
• Carbon Nanotubes: on the Road to Deliver
  Current Drug Delivery. Jul, 2005  |   Pubmed ID: 16305427
• What Role Can Chemistry Play in Cationic Liposome-Based Gene Therapy Research Today?
  Advances in Genetics. 2005  |   Pubmed ID: 16243061
• What Role Can Chemistry Play in Cationic Liposome-based Gene Therapy Research Today?
  Advances in Genetics. 2005  |   Pubmed ID: 16240991
• Synthetic, Self-assembly ABCD Nanoparticles; a Structural Paradigm for Viable Synthetic Non-viral Vectors
  Chemical Society Reviews. Nov, 2005  |   Pubmed ID: 16239997
• Applications of Carbon Nanotubes in Drug Delivery
  Current Opinion in Chemical Biology. Dec, 2005  |   Pubmed ID: 16233988
• Engineering Lipid Vesicles of Enhanced Intratumoral Transport Capabilities: Correlating Liposome Characteristics with Penetration into Human Prostate Tumor Spheroids
  Journal of Liposome Research. 2005  |   Pubmed ID: 16194925
• Synthesis and Application of Integrin Targeting Lipopeptides in Targeted Gene Delivery
  Chembiochem : a European Journal of Chemical Biology. Jul, 2005  |   Pubmed ID: 15937988
• Internal Microdosimetry for Single Cells in Radioimmunotherapy of B-cell Lymphoma
  Cancer Biotherapy & Radiopharmaceuticals. Apr, 2005  |   Pubmed ID: 15869460
• Binding and Condensation of Plasmid DNA Onto Functionalized Carbon Nanotubes: Toward the Construction of Nanotube-based Gene Delivery Vectors
  Journal of the American Chemical Society. Mar, 2005  |   Pubmed ID: 15783221
• Biomedical Applications of Functionalised Carbon Nanotubes
  Chemical Communications (Cambridge, England). Feb, 2005  |   Pubmed ID: 15672140
• Light-sensitive Fusion Between Polymer-coated Liposomes Following Physical Anchoring of Polymerisable Polymers Onto Lipid Bilayers by Self-assembly
  Faraday Discussions. 2005  |   Pubmed ID: 15658785
• Liposome-mediated Radiotherapeutics Within Avascular Tumor Spheroids: Comparative Dosimetry Study for Various Radionuclides, Liposome Systems, and a Targeting Antibody
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jan, 2005  |   Pubmed ID: 15632038
• Functionalized Carbon Nanotubes for Plasmid DNA Gene Delivery
  Angewandte Chemie (International Ed. in English). Oct, 2004  |   Pubmed ID: 15455428
• Binding and Interstitial Penetration of Liposomes Within Avascular Tumor Spheroids
  International Journal of Cancer. Journal International Du Cancer. Nov, 2004  |   Pubmed ID: 15382056
• Rational Design and Engineering of Delivery Systems for Therapeutics: Biomedical Exercises in Colloid and Surface Science
  Advances in Colloid and Interface Science. Dec, 2003  |   Pubmed ID: 14672846