Kristina Broliden Department of Medicine Solna, Center for Molecular Medicine, Karolinska University Hospital Karolinska Institutet Biography Publications Institution JoVE Articles Kristina Broliden has not added a biography. If you are Kristina Broliden and would like to personalize this page please email our Author Liaison for assistance. Publications Human IgM Monoclonal Antibodies Block HIV-transmission to Immune Cells in Cervico-vaginal Tissues and Across Polarized Epithelial Cells in Vitro Scientific Reports. Jul, 2018 | Pubmed ID: 29977063 Experiences and Consequences of Living with Extended-spectrum β-lactamase-producing Bacteria: A Qualitative Study American Journal of Infection Control. Jun, 2018 | Pubmed ID: 29934204 The Vaginal Microbiome Amplifies Sex Hormone-associated Cyclic Changes in Cervicovaginal Inflammation and Epithelial Barrier Disruption American Journal of Reproductive Immunology (New York, N.Y. : 1989). Jul, 2018 | Pubmed ID: 29709092 Human Immunodeficiency Virus-Infected Women Have High Numbers of CD103-CD8+ T Cells Residing Close to the Basal Membrane of the Ectocervical Epithelium The Journal of Infectious Diseases. Jul, 2018 | Pubmed ID: 29272532 Seminal Plasma Induces Inflammation and Enhances HIV-1 Replication in Human Cervical Tissue Explants PLoS Pathogens. May, 2017 | Pubmed ID: 28542587 Genital Injury Signatures and Microbiome Alterations Associated With Depot Medroxyprogesterone Acetate Usage and Intravaginal Drying Practices The Journal of Infectious Diseases. 02, 2017 | Pubmed ID: 28011908 MAIT Cells Reside in the Female Genital Mucosa and Are Biased Towards IL-17 and IL-22 Production in Response to Bacterial Stimulation Mucosal Immunology. 01, 2017 | Pubmed ID: 27049062 Acquisition of Extended Spectrum β-lactamases During Travel Abroad-A Qualitative Study Among Swedish Travellers Examining Their Knowledge, Risk Assessment, and Behaviour International Journal of Qualitative Studies on Health and Well-being. 2016 | Pubmed ID: 27806830 Blood Pressure Regulation by CD4 Lymphocytes Expressing Choline Acetyltransferase Nature Biotechnology. Oct, 2016 | Pubmed ID: 27617738 Innate Invariant NKT Cell Recognition of HIV-1-Infected Dendritic Cells Is an Early Detection Mechanism Targeted by Viral Immune Evasion Journal of Immunology (Baltimore, Md. : 1950). Sep, 2016 | Pubmed ID: 27481843 Frequent Respiratory Viral Infections in Children with Febrile Neutropenia - A Prospective Follow-Up Study PloS One. 2016 | Pubmed ID: 27309354 Improving Adherence to Post-Cervical Biopsy Sexual Abstinence in Kenyan Female Sex Workers American Journal of Reproductive Immunology (New York, N.Y. : 1989). 07, 2016 | Pubmed ID: 27221472 In Situ Staining and Laser Capture Microdissection of Lymph Node Residing SIV Gag-Specific CD8+ T Cells--A Tool to Interrogate a Functional Immune Response Ex Vivo PloS One. 2016 | Pubmed ID: 26986062 Staff Experiences of Caring for Patients with Extended-spectrum β-lactamase-producing Bacteria: A Qualitative Study American Journal of Infection Control. Dec, 2015 | Pubmed ID: 26293998 Non-Cationic Proteins Are Associated with HIV Neutralizing Activity in Genital Secretions of Female Sex Workers PloS One. 2015 | Pubmed ID: 26090884 Respiratory Viruses Associated with Community-acquired Pneumonia in Children: Matched Case-control Study Thorax. Sep, 2015 | Pubmed ID: 26077969 Comparable MRNA Expression of Inflammatory Markers but Lower Claudin-1 MRNA Levels in Foreskin Tissue of HSV-2 Seropositive Versus Seronegative Asymptomatic Kenyan Young Men BMJ Open. Feb, 2015 | Pubmed ID: 25694458 Depot Medroxyprogesterone Acetate Use Is Associated With Elevated Innate Immune Effector Molecules in Cervicovaginal Secretions of HIV-1-Uninfected Women Journal of Acquired Immune Deficiency Syndromes (1999). May, 2015 | Pubmed ID: 25622059 Progesterone-based Intrauterine Device Use is Associated with a Thinner Apical Layer of the Human Ectocervical Epithelium and a Lower ZO-1 MRNA Expression Biology of Reproduction. Mar, 2015 | Pubmed ID: 25588510 HIV Acquisition is Associated with Increased Antimicrobial Peptides and Reduced HIV Neutralizing IgA in the Foreskin Prepuce of Uncircumcised Men PLoS Pathogens. Oct, 2014 | Pubmed ID: 25275513 Expression Profiles of Antimicrobial Peptides in the Genital Tract of Women Using Progesterone Intrauterine Devices Versus Combined Oral Contraceptives American Journal of Reproductive Immunology (New York, N.Y. : 1989). Nov, 2014 | Pubmed ID: 25087845 A Comparative Proteomic Analysis of the Soluble Immune Factor Environment of Rectal and Oral Mucosa PloS One. 2014 | Pubmed ID: 24978053 Presence of CD8+ T Cells in the Ectocervical Mucosa Correlates with Genital Viral Shedding in HIV-infected Women Despite a Low Prevalence of HIV RNA-expressing Cells in the Tissue Journal of Immunology (Baltimore, Md. : 1950). Apr, 2014 | Pubmed ID: 24639358 Clinical Utility of PCR for Common Viruses in Acute Respiratory Illness Pediatrics. Mar, 2014 | Pubmed ID: 24567027 Stable CD4 Expression and Local Immune Activation in the Ectocervical Mucosa of HIV-infected Women Journal of Immunology (Baltimore, Md. : 1950). Oct, 2013 | Pubmed ID: 24006463 A Systems Biology Examination of the Human Female Genital Tract Shows Compartmentalization of Immune Factor Expression Journal of Virology. May, 2013 | Pubmed ID: 23449785 Bacteremia in Swedish Hematological Patients with Febrile Neutropenia: Bacterial Spectrum and Antimicrobial Resistance Patterns Scandinavian Journal of Infectious Diseases. Apr, 2013 | Pubmed ID: 23113817 Cervicovaginal HIV-1-neutralizing Immunoglobulin A Detected Among HIV-1-exposed Seronegative Female Partners in HIV-1-discordant Couples AIDS (London, England). Nov, 2012 | Pubmed ID: 22948273 A Genetic Polymorphism of FREM1 is Associated with Resistance Against HIV Infection in the Pumwani Sex Worker Cohort Journal of Virology. Nov, 2012 | Pubmed ID: 22915813 No Difference in Keratin Thickness Between Inner and Outer Foreskins from Elective Male Circumcisions in Rakai, Uganda PloS One. 2012 | Pubmed ID: 22815984 Viral Findings in Adult Hematological Patients with Neutropenia PloS One. 2012 | Pubmed ID: 22570724 HIV-neutralizing Activity of Cationic Polypeptides in Cervicovaginal Secretions of Women in HIV-serodiscordant Relationships PloS One. 2012 | Pubmed ID: 22389677 Mannose-binding Lectin 2 Polymorphisms Do Not Influence Frequency or Type of Infection in Adults with Chemotherapy Induced Neutropaenia PloS One. 2012 | Pubmed ID: 22363494 In Situ Distribution of HIV-binding CCR5 and C-type Lectin Receptors in the Human Endocervical Mucosa PloS One. 2011 | Pubmed ID: 21984929 Detection of Intraepithelial and Stromal Langerin and CCR5 Positive Cells in the Human Endometrium: Potential Targets for HIV Infection PloS One. 2011 | Pubmed ID: 21738639 Flocked Nasal Swab Versus Nasopharyngeal Aspirate for Detection of Respiratory Tract Viruses in Immunocompromised Adults: a Matched Comparative Study BMC Infectious Diseases. Nov, 2010 | Pubmed ID: 21110854 Innate Molecular and Anatomic Mucosal Barriers Against HIV Infection in the Genital Tract of HIV‐exposed Seronegative Individuals The Journal of Infectious Diseases. Nov, 2010 | Pubmed ID: 20887223 HIV-1 Exposed Uninfected Men Who Have Sex with Men Have Increased Levels of Salivary CC-chemokines Associated with Sexual Behavior AIDS (London, England). Jun, 2010 | Pubmed ID: 20549845 Induction of Systemic HIV-1-specific Cellular Immune Responses by Oral Exposure in the Uninfected Partner of Discordant Couples AIDS (London, England). Apr, 2010 | Pubmed ID: 20397304 Abundant Expression of HIV Target Cells and C-type Lectin Receptors in the Foreskin Tissue of Young Kenyan Men The American Journal of Pathology. Jun, 2010 | Pubmed ID: 20395432 Respiratory Viruses, a Common Microbiological Finding in Neutropenic Children with Fever Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology. Mar, 2010 | Pubmed ID: 20056482 Abundant and Superficial Expression of C-type Lectin Receptors in Ectocervix of Women at Risk of HIV Infection Journal of Acquired Immune Deficiency Syndromes (1999). Jul, 2009 | Pubmed ID: 19363450 Parvovirus B19 Infection Seminars in Fetal & Neonatal Medicine. Aug, 2009 | Pubmed ID: 19231308 Levels of Innate Immune Factors in Genital Fluids: Association of Alpha Defensins and LL-37 with Genital Infections and Increased HIV Acquisition AIDS (London, England). Jan, 2009 | Pubmed ID: 19114868 Oral HIV-exposure Elicits Mucosal HIV-neutralizing Antibodies in Uninfected Men Who Have Sex with Men AIDS (London, England). Jan, 2009 | Pubmed ID: 19114861 Persistence of Human Parvovirus B19 in Multipotent Mesenchymal Stromal Cells Expressing the Erythrocyte P Antigen: Implications for Transplantation Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Oct, 2008 | Pubmed ID: 18804048 HIV-neutralizing Immunoglobulin A and HIV-specific Proliferation Are Independently Associated with Reduced HIV Acquisition in Kenyan Sex Workers AIDS (London, England). Mar, 2008 | Pubmed ID: 18356602 HIV-1 Neutralizing Activity is Correlated with Increased Levels of Chemokines in Saliva of HIV-1-exposed Uninfected Individuals Current HIV Research. Jan, 2008 | Pubmed ID: 18288972 The Antimicrobial Peptide LL-37 Inhibits HIV-1 Replication Current HIV Research. Jul, 2007 | Pubmed ID: 17627504 Plasma and Mucosal Fluid from HIV Type 1-infected Patients but Not from HIV Type 1-exposed Uninfected Subjects Prevent HIV Type 1-exposed DC from Infecting Other Target Cells AIDS Research and Human Retroviruses. Jan, 2007 | Pubmed ID: 17263639 Aberrant Cellular Immune Responses in Humans Infected Persistently with Parvovirus B19 Journal of Medical Virology. Jan, 2006 | Pubmed ID: 16299714 Prolonged Activation of Virus-specific CD8+T Cells After Acute B19 Infection PLoS Medicine. Dec, 2005 | Pubmed ID: 16253012 Slow Clearance of Human Parvovirus B19 Viremia Following Acute Infection Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Oct, 2005 | Pubmed ID: 16163641 Sustained CD8+ T-cell Responses Induced After Acute Parvovirus B19 Infection in Humans Journal of Virology. Sep, 2005 | Pubmed ID: 16140790 Non-hydropic Intrauterine Fetal Death More Than 5 Months After Primary Parvovirus B19 Infection Journal of Perinatal Medicine. 2005 | Pubmed ID: 15843271 Detection of Parvovirus B19, Cytomegalovirus and Enterovirus Infections in Cases of Intrauterine Fetal Death Journal of Perinatal Medicine. 2004 | Pubmed ID: 15576274 Parvovirus B19 Capsid Protein VP2 Inhibits Hematopoiesis in Vitro and in Vivo: Implications for Therapeutic Use Experimental Hematology. Nov, 2004 | Pubmed ID: 15539086 Human Parvovirus B19 DNA is Not Detected in Guthrie Cards from Children Who Have Developed Acute Lymphoblastic Leukemia Pediatric Blood & Cancer. Apr, 2004 | Pubmed ID: 14966833 Detection of Human Parvovirus B19 Infection in First-trimester Fetal Loss Obstetrics and Gynecology. May, 2002 | Pubmed ID: 11978289 Ex Vivo Infección de la Mucosa Genital tejido linfoide humano y mujer con Virus de inmunodeficiencia humana 1 y Histoculture Andrea Introini1,2, Christophe Vanpouille2, Wendy Fitzgerald2, Kristina Broliden1, Leonid Margolis2 1Department of Medicine Solna, Center for Molecular Medicine, Karolinska University Hospital, Karolinska Institutet, 2Section of Intercellular Interactions, Eunice Shriver National Institute of Child Health and Human Development, National Institutes of Health JoVE 57013 Immunology and Infection
Ex Vivo Infección de la Mucosa Genital tejido linfoide humano y mujer con Virus de inmunodeficiencia humana 1 y Histoculture Andrea Introini1,2, Christophe Vanpouille2, Wendy Fitzgerald2, Kristina Broliden1, Leonid Margolis2 1Department of Medicine Solna, Center for Molecular Medicine, Karolinska University Hospital, Karolinska Institutet, 2Section of Intercellular Interactions, Eunice Shriver National Institute of Child Health and Human Development, National Institutes of Health JoVE 57013 Immunology and Infection
